Science Links Japan | Japanese Pharmacology & Therapeutics

List of Jounal Titles

A to Z index of Journal Title. Choose a letter.

A/ B/ C/ D/ E/ F/ G/ H/ I/ J/ K/ L/ M/ N/ O/ P/ Q/ R/ S/ T/ U/ V/ W/ X/ Y/ Z/ 0/ 1/ 2/ 3/ 4/ 5/ 6/ 7/ 8/ 9

Japanese Pharmacology & Therapeutics

Suppl.4

New Histamine H2-Receptor Antagonist Pibutidine Hydrochloride. Phase I Clinical Study of Pibutidine Hydrochloride.
New Histamine H2-Receptor Antagonist Pibutidine Hydrochloride. Clinical Study of Pibutidine Hydrochloride(IT-066) on Peptic Ulcer: Early Dose Finding by Open Study.
New Histamine H2-Receptor Antagonist Pibutidine Hydrochloride. Dose finding study of pibutidine hydrochloride on peptic ulcer.
New Histamine H2-Receptor Antagonist Pibutidine Hydrochloride. Clinical Study of Pibutidine Hydrochloride(IT-066) in the Treatment of Peptic Ulcer: A Multicenter Double-Blind Comparative Study with Famotidine.
New Histamine H2-Receptor Antagonist Pibutidine Hydrochloride. Clinical Effect of Pibutidine Hydrochloride on Recurrent Ulcer after Gastric Surgery.
New Histamine H2-Receptor Antagonist Pibutidine Hydrochloride. Clinical Effect of Pibutidine Hydrochloride on Endocrine Function and Healing in Patients with Gastric Ulcer.
New Histamine H2-Receptor Antagonist Pibutidine Hydrochloride. Clinical Evaluation of Pibutidine Hydrochloride on Reflux Esophagitis: Comparison of 20mg Daily and 40mg Daily.
New Histamine H2-Receptor Antagonist Pibutidine Hydrochloride. Effect of IT-066(Pibutidine Hydrochloride) on Gastric acid Secretion(First report): Dose Finding with 24 Hours Gastric Juice.
New Histamine H2-Receptor Antagonist Pibutidine Hydrochloride. Effect of IT-066(Pibutidine Hydrochloride) on Gastric Acid Secretion(Second Report): Comparative Study on UID Evening Dose and BID Evening and Morning Dose with 24 hours Gastric Juice.
New Histamine H2-Receptor Antagonist Pibutidine Hydrochloride. Acid Suppression Profile of Pibutidine Hydrochloride with 24-hour Intragastric pH Monitoring: Comparison of Treatment Regimens of 40mg Once Daily and 20mg Twice Daily.
Suppl.5
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). Pharmacokinetic Studies of (.+-.)-5-methoxy-2-{[(4-methoxy-3,5-dimethylpyrid-2-yl)methyl]sulfinyl}-1H-imidazo[4,5-b]pyridine(TU-199). (VIII). Metabolism of TU-199 in Human.
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). Phase I Study of TU-199: Safety, Pharmacology and Pharmacokinetics with Single and Multiple Dosing.
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). Gastric Acid Secretion-inhibitory Effect of TU-199 by 24-hour Intragastric pH Monitoring: A Trial of Clinical Pharmacology with Healthy Volunteers.
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). A Pharmacokinetic Study of TU-199 in Aged Healthy Volunteers.
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). Clinical Evaluation of TU-199(Benatoprazole) in Patients with Gastric or Duodenal Ulcer: Early Phase II Study.
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). Dose Finding Study of the New Anti-ulcer Agent TU-199(Benatoprazole) on Gastric and Duodenal Ulcers: Clinical Late Phase II Study.
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). Clinical Evaluation of Bed-time Treatment with a New Proton Pump Inhibitor TU-199(Benatoprazole) in Peptic Ulcers.
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). Clinical Study of TU-199(Benatoprazole), a New Proton Pump Inhibitor: Effect on Endocrine Function and Healing in Patients with Gastric and Duodenal Ulcer.
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). Effects of the New Anti-ulcer Agent TU-199(Benatoprazole) on Stomal Ulcers.
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). Clinical Usefulness of TU-199(Benatoprazole), a New Proton Pump Inhibitor on Reflux Esophagitis.
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). Clinical Evaluation of TU-199(Benatoprazole) in Reflux Esophagitis.
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). Zollinger-Ellison Syndrome Successfully Treated with a New Proton Pump Inhibitor TU-199: Report of a Case.
Clinical Evaluations of a New Proton Pump Inhibitor Benatoprazole(TU-199). Treatment of TU-199 on Zollinger-Ellison Syndrome: A Case Report.
Suppl.1
Acute Intravenous Toxicity Study of Amrubicin Hydrochloride(SM-5887) in Rats.
Single Intravenous Toxicity Study of Amrubicin Hydrochloride(SM-5887) in Dogs.
Four-week Intravenous Toxicity Study on Amrubicin Hydrochloride(SM-5887) in Rats.
Ninety-day Intravenous Toxicity Study of Amrubicin Hydrochloride(SM-5887) in Rats Followed by 90-day Recovery Study.
Four-week Intravenous Toxicity Study of Amrubicin Hydrochloride(SM-5887) in Dogs.
Five-day Intravenous Comparative Toxicity Study on Amrubicin Hydrochloride(SM-5887) and Doxorubicin Hydrochloride(DXR) in Male Rats.
A Repeated Dose Toxicity Study of Amrubicin Hydrochloride(SM-5887) Administered Intravesically to Beagle Dogs for 2 Weeks Followed by a 3 Week Recovery Period.
Six-month Intravenous Toxicity Study of Amrubicin Hydrochloride(SM-5887) in Rats Followed by 6-month Recovery Study.
Six-month Intravenous Toxicity Study of Amrubicin Hydrochloride(SM-5887) in Beagle Dogs followed by 6-month Recovery Study.
Reproductive and Developmental Toxicity Studies of Amrubicin Hydrochloride(SM-5887) (1)-Fertility Study in Rats.
Reproductive and Developmental Toxicity Studies of Amrubicin Hydrochloride(SM-5887) (2)-Teratogenicity Study by Intravenous Administration in Rats.
Reproductive and Developmental Toxicity Studies of Amrubicin Hydrochloride(SM-5887) (3)-Teratogenicity Study in Rabbits.
Reproductive and Developmental Toxicity Studies of Amrubicin Hydrochloride(SM-5887) (4)-Perinatal and Postnatal Study in Rats.
Antigenicity Study on Amrubicin Hydrochloride(SM-5887).
Reverse Mutation Test of Amrubicin Hydrochloride(SM-5887) in Bacterial Systems.
In vitro Chromosomal Aberration Test on Amrubicin Hydrochloride(SM-5887) in Chinese Hamster Ovary Cells(CHO-K1).
Micronucleus Test on Amrubicin Hydrochloride(SM-5887) in CD-1 Mice.
Vascular Irritation Study of Amrubicin Hydrochloride(SM-5887) in Rabbits.
Studies on the Metabolic Fate of Amrubicin Hydrochloride(SM-5887), a Novel Antitumor Agent (5)-Placental Transfer and Excretion into Milk.
Studies on the Metabolic Fate of Amrubicin Hydrochloride(SM-5887), a Novel Antitumor Agent (6)-Pharmacokinetic Studies of Amrubicinol, the Major Bioactive Metabolite of Amrubicin, in Rats.
Studies on the Metabolic Fate of Amrubicin Hydrochloride(SM-5887), a Novel Antitumor Agent (7)-Effect of SM-5887 on Drug Metabolizing Enzyme System in Rats.
Studies on the Metabolic Fate of Amrubicin Hydrochloride(SM-5887), a Novel Antitumor Agent (8)-Drug-drug Interactions of SM-5887 in Protein Binding.
Studies on the Metabolic Fate of Amrubicin Hydrochloride(SM-5887), a Novel Antitumor Agent (9)-In Vivo Chiral Conversion of SM-5887 and Stereoselectivity of Reduction of the Carbonyl Group at the C-13 Position.
Suppl.2
Single-dose Percutaneous Toxicity Study of OCT in Rats.
Single-dose Percutaneous Toxicity Study of OCT in Dogs.
One-month Percutaneous Toxicity of OCT in Rats.
One-month Percutaneous Toxicity of OCT in Dogs.
Six-month Percutaneous Toxicity Study of OCT in Rats.
Six-month Percutaneous Toxicity Study of OCT in Dogs.
Twelve-month Percutaneous Toxicity Study of OCT in Dogs.
Fertility Study of OCT in Rats by Percutaneous Administration.
Study for Effects on Embryo-fetal Development in Rats Treated Percutaneously with OCT.
Study for Effects of OCT Administered Percutaneously on Embryo-fetal Development in Rabbits.
Dermatotoxicity Studies of OCT Ointment in Guinea Pigs. Skin Sensitization Test, Phototoxicity Test and Photosensitization Test.
Suppl.6
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Dai-saiko-to (TJ-8).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Sho-saiko-to (TJ-9).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Saiboku-to (TJ-96).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Sairei-to (TJ-114).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Hochu-ekki-to (TJ-41).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Rikkunshi-to (TJ-43).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Choto-san (TJ-47).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Shakuyaku-kanzo-to (TJ-68).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Gosha-jinki-gan (TJ-107).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Kami-shoyo-san (TJ-24).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Hachimi-jio-gan (TJ-7).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Toki-shakuyaku-san (TJ-23).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Sho-seiryu-to (TJ-19).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Keishi-bukuryo-gan (TJ-25).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Saiko-keishi-to (TJ-10).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Saiko-ka-ryukotsu-borei-to (TJ-12).
Toxicological Studies of Kampo Extract Preparations (2)-Mutagenicity Study. Mutagenicity Studies of Oren-gedoku-to (TJ-15).
Suppl.3
Significance of Laparoscopic Findings for Evaluating Clinical Features in Patients with Idiopathic Portal Hypertension.
What is PET Image Using C15O2 Inhalation Steady State Method? Association with H215O Bolus Injection Dynamic PET Study.
Portal Blood Velocity with Doppler Ultrasonography in Patients with Chronic Liver Disease.
A Study of Liver Hemodynamics in Alcoholic Liver Diseases. Comparison of Color Doppler Portal Blood Flow Measurements and Hepatic Blood Flow Scintigraphy.
Splenomegaly in Liver Cirrhosis.
Clinical Significance of T1-weighted MRI Hyperintensity of Globus Pallidus in Patients with Chronic Liver Disease.
Assessment of Liver Cirrhosis by the Magnetization Transfer Contrast Technique in the Brain of Patients.
Altered Hepatocyte Tight Junction in Rat Model of Inflammatory Bowel Disease.
Altered Tight Junctions of Hepatocytes and Biliary Epithelial Cells in a Rat Model of Graft-versus-host Disease.
Formation of Gap Junction(GJ) and its Biological Significance in Human and Rat Liver with Hepatocellular Carcinoma. In Comparison with the Development of GJ during Ontogenesis.
Gender Differemces of Hepatic Injury and Cytokine Production in Concanavalin A Induced Hepatitis in Mice.
Nitric Oxide and Interleukin-10 Production during Endotoxemia.
Effects of Nitric Oxide on the Liver in vivo. An Electron Spin Resonance Study.
Vitamin A Reduces Hepatic Fibrosis in Rats Induced by Dimethylnitrosamine or Pig Serum.
Induction of Apoptotic Cell Death in Human Hepatocellular Carcinoma SK-HEP-1 cells by a Polyamine Synthesis Inhibitor, Methylglyoxal bis(cyclopentylamidinohydrazone)(MGBCP).
Effect of Cysteine on the Rat Cultured Hepatocyte. Interation with Ursodeoxycholic Acid when Intracellular Glutathione Levels were Depleted.
Clinical Assessment of Nutritional Therapy Using the Branched Chain Amino Acids/Tyrosine Ratio.
Expression of Vascular Endothelial Growth Factor in Hepatocytes of Regenerating Rat Liver.
Gene Analysis of Hydroxymethylbilane Synthase in Two Japanese Families of Acute Intermittent Porphyria-a Founder Effect.
A Case Report of Idiopathic Hemochromatosis without HFE Gene Mutations, C282Y and H63D.
A Japanese Family with Compound Heterozygote of Wilson's Disease Gene.
Mutation Analysis of a Family with Alagille Syndrome.
Genetic Basis of Fasting Hyperbilirubinemia.
Heterozygous Missense Mutations of the Bilirubin UDP-glycosyltransferase Gene and the Activities of the Enzyme.
A Splice Mutation in the Human Canalicular Multispecific Organic Anion Transporter Gene Causes Dubin-Johnson Syndrome.
A Case of Dubin Johnson Syndrome.
A New Enzymatic Assay for Measuring Serum Conjugated Bilirubin and Its Clinical Relevance.
Usefulness of Measuring Conjugated Bilirubin Concentration in Hepatobiliary Disorders. In Comparison with Total Bilirubin, Direct Bilirubin and Total Bile Acid Concentrations.
Diagnostic Criteria of Gilbert's Syndrome.
Different Paracellular Routes for Bile Regurgitation in Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis.
Effect of Phalloidin on Fatty Acid Composition of Hepatocyte.
Effects of Conjugated Bile Acids and BSP on Biliary Excretion of Taurochenodeoxycholate-3-sulfate.
Induction of the Expression of Transporters (Mrp3/MLP-2,P-gp) and P450 Isozymes in the Rat Hepatocytes.
The Characterization of Relationship between Chemical Structure of Bile Acids and Recognition Properties by Canalicular Bile Acid Transporter(cbat).
Analysis of Drug-Drug Interaction in Biliary Excretion. Effect of Several Drugs on Biliary Excretion of Anticancer Agent, Irinotecan Hydrochloride (CPT-11), and its Active Metabolite (SN-38).
Transport of Organic Anions Across the Hepatocyte Canalicular Membrane.
Suppl.7
Suicide Gene Therapy of Hepatocellular Carcinoma Using EBV-based Episomal Vector/Dendrimer Complex in vitro.
Analysis of Intrahepatic Invasion and Metastasis of Hepatocellular Carcinoma in Normal and Cirrhotic Livers Using Fluorescent Dye-labeled Hepatocellular Carcinoma Cells.
Protective Effect of Very Low Dose-LPS Pre-treatment on Experimental Acute Hepatic Injury.
Gender-associated Differences in Concanavalin A-induced Hepatitis in Mice.
Effect of Nitric Oxide on Hepatic Cytochrome P450 in Endotoxemia.
Nitric Oxide-induced Inhibition of Cytochrome P450.
Distribution of Proliferative Sinusoidal Endothelial Cells in Liver Regeneration after Partial Hepatectomy in Rats.
Quantitative Demonstration of Porto-systemic Shunt by Alterd 201 Thallium Chloride Portal Scintigraphy in Patients with Chronic Liver Disease.
Stimulatory Effect of Central Thyrotropin-releasing Hormone on Hepatic Blood Flow.
Serum Matrix Metalloproteinase-2 and Liver Fibrosis.
Significance of Serum Thioredoxin in Patients with Hepatitis C Virus-related Chronic Liver Diseases.
Cysteine Catabolism in Rat Hepatocytes after Short-term Culture.
Heterogeneity of Gap Junctional Channels in Hepatic Lobule.
Perticipation of IL-18 in Human Cholestatic Cirrhosis and Acute Rejection. Analysis in Living Donor Liver Transplantation.
Effect of Immunosuppressants on Bile Acid Kinetics. Comparative Study of Cyclosporine with Tacrolimus.
Analysis of Bilirubin and Bile Acid Fractions in Serum and Bile Juice after Living Related Liver Transplantation.
Coagulopathy after Bilirubin Adsorption in a Living Related Partial Liver Transplant Recipient.
Primary Sclerosing Cholangitis. 3 Cases Report.
Living Donor Liver Transplantation for Alagille's Syndrome.
Living Related Liver Transplantation in 2 Families of Byler's Disease.
Induction of Heme Oxygenase-1 Attenuates Hepatobiliary Dysfunction Elicited by Cold Ischemia and Reperfusion in the Rat Liver. Role of Bilirubin.
Effects of UDCA on Unusual Trihydroxy Bile Acids in the Urine of Patients with Liver Diseases.
Effects of Phalloidin on Biliary Excretion of Cholephilic Compounds.
Effect of Obstructive Cholestasis on Liver Plasma Membrane Fluidity. Relation to Phospholipid Molecular Species of Lipid Bilayers.
Effects of Bilirubin Ditaurate on Liver Canalicular Membrane Fluidity and Lipid Composition.
Effect of Enzyme Induction on Biliary Excretion of Irinotecan Hydrochloride (CPT-11), and its Active Metabolite (SN-38).
Prediction for drug interaction via hepatic transporters.
cMOAT Mutations in Two Patients with Dubin-Johnson Syndrome(DJS).
Inhibitory Effect of Quinidine and Quinine on the Oatp1- and Oatp2-Mediated Transport.
Analysis of the Mechanism for the Induction of MRP3.
Characterization the Mechanism for the Biliary Excretion of Bile Acids Across the Canalicular Membrane.
Clinical Usefulness of Conjugated Bilirubin Measurement.
Bilirubin for a Laboratory Test.
1
Trial case under new GCP. Present state of medical institutions. Function of trial case management room.
Trial case under new GCP. Present state of medical institutions. Challenge of national university hospitals 1.
Trial case under new GCP. Present state of medical institutions. Challenge of national university hospitals 2.
Trial case under new GCP. Present state of medical institutions. Challenge of private university hospitals.
Trial case under new GCP. Present state of medical institutions. Practice of CRC/SC (nurse) business.
Trial case under new GCP. Present state of medical institutions. Practice of CRC (pharmacist) business.
Effect of Ca2+ Channel Blocker Cilnidipine in Comparison with that of Amlodipine and Nifedipine on Insulin Resistance in Dahl-S Rats.
Effect of the Combined Use of EPA-E and a Ca2+ Channel Blocker on Insulin Resistance in Dahl-S Rats.
Effect of Naftopidil, a New .ALPHA.1-adrenoceptor Blocking Agent, on the Contractile Response of Isolated Rat Thoracic Aortas and Portal Veins as well as Blood Pressure Responses to Tilting in Conscious Rabbits.
Effects of Human Growth Hormone in Hypercholesterolemic Hamsters.
Improving Effect of Gastrointestinal-prokinetic Agent, Itopride Hydrochloride on Drug-induced Gastric Dysmotility in Conscious Dogs.
A Case Report of an Acute Hemorrhaging Gastric Ulcer Effectively Treated with H2-blocker, Proton Pump Inhibitor and Ecabet Sodium.
2
The Role of the Clinical Research Associate(CRA) in Japan's Clinical Research Studies.
Fibrin-dependent Plasminogen Activation, Binding Affinity to Fibrin and Fibrinolytic Activity of Lanoteplase (SUN 9216).
Thrombolytic Activity in Jugular Vein Thrombosis and Bleeding Potential of Lanoteplase (SUN 9216) in Rabbits.
Effect of Lanoteplase (SUN 9216) on Plasma on Hemostatic Parameters, Platelet Aggregation and Gastric Hemorrhage Induced by Aspirin.
Potent Vasodilative Action of Cilnidipine on Glomerular Arterioles in Rat Hydronehrotic Kidney.
Suppressive Effects of FPF1100 (Selegiline Hydrochloride) on Tyramine Uptake are Independent of Its Inhibitory Activity to Monoamine Oxidase-type B.
Comparison Study of Antiulcer Drug (Maalox Dry Suspension Granule) in Rat about the Drug Suspended and not Suspended.
Sticking Grade and Dispersity of Antiulcer Drug (Maalox Dry Suspension Granule) in Dog's Stomach: Comparison Study about the Drug Suspended and not Suspended.
Effect of Pure Lactulose (Piarle Dry Syrup) on Growth of Intestinal Bifidobacterium in Rats.
Inhibitory Effect of a Novel Eyewash Agent EWJ on Ocular Irritation Induced by Chlorine in Rabbits.
Safe and Effective Treatment of Pirmenol to Suppress Ventricular Premature Contractions(VPCs) in Patients with Underlying Heart Disease.
Experience in Use of Solcoseryl Ointment in Elderly Patients Suffering from Decubitus.
Studies on Contrast Effect and Safety of Ioversol in Intravenous Urography.
3
Effect of Pibutidine Hydrochloride, a Histamine H2-receptor Antagonist, on Gastric Acid Secretion and Ulcer Formation-induced by Various Experimental Model in Rats.
Anti-secretory and Anti-ulcer Effect of Pibutidine Hydrochloride, Histamine H2-receptor Antagonist, in Rats.
Effect of Pibutidine, Histamine H2-receptor Antagonist, on [14C]Aminopyrine Accumulation in Rabbit Isolated Parietal Cells.
Protective Effect of Pibutidine Hydrochloride on the Gastric Mucosal Lesions in Rats.
Effect of a Histamine H2-receptor Antagonist Pibutidine Hydrochloride on the Healing of Acetic Acid-induced Gastric Ulcer.
Involvement of Nitric Oxide in the Curative Effect of a Histamine H2-receptor Antagonist Pibutidine Hydrochloride on the Acetic Acid-induced Gastric Ulcer in Rats.
Effect of a Histamine H2-receptor Antagonist Pibutidine Hydrochloride on the Mitogenic Activity and Epidermal Growth Factor Content in the rat Gastric Juice.
Single Dose Toxicity Studies of 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride (Pibutidine Hydrochloride) in Mice, Rats and Dogs.
Repeated Dose Toxicity Study of 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride (Pibutidine Hydrochloride) in Rats. (1). 13-Week Oral Toxicity Study with 4-Week Recovery Test.
Repeated Dose Toxicity Study of 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride (Pibutidine Hydrochloride) in Rats. (2). 52-Week Oral Toxicity Study in Rats with 5-Week Recovery Test.
Reproductive and Developmental Toxicity Studies of 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride (Pibutidine Hydrochloride). (1). Fertility Study in Rats.
Reproductive and Developmental Toxicity Studies of 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride (Pibutidine Hydrochloride). (2). Teratogenicity Study in Rats.
Reproductive and Developmental Toxicity Studies of 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride (Pibutidine Hydrochloride). (3). Teratogenicity Study in Rabbits.
Reproductive and Developmental Toxicity Studies of 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride (Pibutidine Hydrochloride). (4). Prenatal and Postnatal Study in Rats.
Antigenicity Study of 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride (Pibutidine Hydrochloride).
Mutagenicity Studies of 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride (Pibutidine Hydrochloride).
Effects of Rafutidine on Development of Mucosal Lesions and Changes in Transmucosal Potential Difference Induced by Monochloramine in Rat Stomachs.
Phase I Safety Study of Interferon Alfacon-1 in Healthy Volunteers. Pharmacodynamic Response.
Clinical Efficacy and Safety of Pirmenol in Patients of Arrhythmia with Organic Heart Diseases.
Late Phase II Study of Sepimonstat Mesilate (FUT-187) in Postgastrectomy Reflux Esophagitis. Clinical Optimum Dose in a Double Blind Study (Revised Report).
Clinical Evaluation of the OTC Product K98-01 (KINKAN) on the Shoulder Stiffness, Backache, Confusion, Sprain.
4
A Report on SMO for Clinical Research in USA.
Cardiovascular Effects of a Histamine H2-receptor Antagonist Pibutidine Hydrochloride and its Metabolite M-8.
General Pharmacological Studies of a Histamine H2-receptor Antagonist Pibutidine Hydrochloride and its Metabolites, M-5 and M-8.
Disposition of Pibutidine Hydrochloride, 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride(IT-066) (1): Absorption, Distribution and Excretion after Single Administration to Rats.
Disposition of Pibutidine Hydrochloride, 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride(IT-066) (2): Transfer into Fetus and Milk after Single Oral Administration, and Absorption, Distribution and Excretion after Repeated Oral Administration to Rats.
Disposition of Pibutidine Hydrochloride, 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride(IT-066) (3): Absorption and Excretion after Single Administration to Dogs.
Disposition of Pibutidine Hydrochloride, 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride(IT-066) (4): Metabolism in Dogs.
Disposition of Pibutidine Hydrochloride, 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride(IT-066) (5): Metabolism in Rats.
Disposition of Pibutidine Hydrochloride, 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride(IT-066) (6): Absorption, Distribution and Excretion after Single Administration of 14C-IT-066(C) in Rats.
Disposition of Pibutidine Hydrochloride, 3-amino-4-[[(Z)-4-[[4-(piperidinomethyl)-2-pyridyl]oxy]-2-butenyl]amino]-3-cyclobutene-1,2-dione monohydrochloride(IT-066) (7): Metabolism of 14C-IT-066(C) in Rats.
Effect of Glycyrrhizin on Monoamine Dynamics in the Rat Brain.
A Newly Developed Wound Dressing Made of Alginate Fiber Containing Zeolite Substituted by Silver and Zinc: Fundamental Study.
Effect of Proton Pump Inhibitor, Rabeprazole, on Gastric Acid Secretion: Inhibitory Effect on Gastrin-stimulated Acid Secretion by 10mg Dosing of Rabeprazole in Healthy Male Volunteers.
Development of Newly Formulated Antimicrobial Wound Dressing(Non Woven Sheet of Ag-Zn Zeolite Impregnated Ca Alginate Fiber): A Multi-centric Clinical Study.
Economic Evaluation of Cholesterol-lowering Therapy for Hypercholesterolemia, Cost-Effectiveness of HMG-CoA Reductase Inhibitors.
5
Effects of Granulocyte-colony Stimulating Factor(G-CSF) on the Function of Neutrophils.
Studies on the Sleep-inducing Effect of Diphenhydramine Hydrochloride.
Oral 3-month Repeated-dose Toxicity Study of Treated Water by Electro Clean in Rats.
Analgesic and Ulcerogenic Activities of Mofezolac. A Comparative Study with Other Non-steroidal Anti-inflammatory Drugs.
The Combined Administration of Cilnidipine, an L-type and N-type Ca2+ Channel Blocker, and Alacepril, an Angiotensin-converting Enzyme Inhibitor, Reduces Renal Nerve Stimulation-induced Noradrenaline Release in Anesthetized Dogs.
Effect of Ginseng Vinegar Drinks Supplemented with Xylooligosaccharide on Defecation Frequency and Fecal Conditions.
Clinical Evaluation of TO-020 in Orthopaedic field.
Clinical Evaluation of TO-020 on Osteoarthritis on the Knee.
Effectiveness and Safety of Banabamin Tablet Containing Extract from Banaba in Patients with Mild Type 2 Diabetes.
Clinical Evaluation of Egualen Sodium in the Treatment of Gastric Ulcer(A Revised Edition). A Multicenter Double-blind Comparative Study with Cetraxate Hydrochloride.
Combined Therapy with Egualen Sodium and Cimetidine for Patients with Gastric Ulcer First Article of a Report(A Revised Edition): Clinical Evaluation of Initial Treatment. A Multicenter Controlled Study in Comparison with Cimetidine Alone.
Combined Therapy with Egualen Sodium and Cimetidine for Patients with Gastric Ulcer. Second Article of a Report(A Revised Edition): Clinical Evaluation for the Prevention of Gastric Ulcer Relapse. A Maintenance Study in Comparison with Cimetidine Alone.
6
A Single Oral Dose Toxicity Study of Ipecac Fluidextract in Rats.
A Single Oral Dose Toxicity Study of Ipecac Fluidextract in Infant Rats.
A Single Oral Dose Toxicity Study of Ipecac Fluidextract in Beagle Dogs.
A Single Oral Dose Toxicity Study of Ipecac Fluidextract in Infant Beagle Dogs.
A Four-week Repeated Oral Dose Toxicity Study of Ipecac Fluidextract in Rats Followed by a Four-week Recovery Period.
A Four-week Repeated Oral Dose Toxicity Study of Ipecac Fluidextract in Infant Rats Followed by a Four-week Recovery Period.
A Four-week Repeated Oral Dose Toxicity Study of Ipecac Fluidextract in Beagle Dogs Followed by a Four-week Recovery Period.
A Four-week Repeated Oral Dose Toxicity Study of Ipecac Fluidextract in Infant Beagle Dogs Followed by a Four-week Recovery Period.
Mutagenicity Studies of Ipecac Fluidextract.
Single-dose Intravenous Toxicity Study of Rituximab(IDEC-C2B8) in Cynomolgus Monkeys.
Single Oral Dose Toxicity Study of Glucosol in Rats.
Glucosol Effect on Blood Glucose in Rats.
Anti-secretory Effect of Pibutidine Hydrochloride on Histamine-induced Gastric Acid Secretion in Heidenhain Pouch Dogs.
Comparison of Nateplase with Monteplase in Fibrin Selective Properties.
Studies on the Metabolic Fate of Egualen Sodium, Absorption, Metabolism and Excretion after Administration to Rats, Mice and Dogs.
Experience of Immediate Beta Blocker Bisoprolol Therapy Following Interventional Treatment in Patients with Acute Myocardial Infarction.
A Case in which Nicorandil was Remarkably Effective in Suppressing an Attack of Vasospastic Angina that was Resistant to the Treatment with Diltiazem and Nitrate.
New Method for Investigation of Direct Effect of Gastrointestinal Drugs Using Endoscopy.
Recent Progress in the Research and Therapy of CIDP(included MMN).
7
Two-generation Reproduction Study with Teratology Test of .EPSILON.-poly-L-lysine by Dietary Administration in Rats.
Effect of Zaltoprofen, a Non-steroidal Anti-inflammatory Drug, on the Healing of Acetic Acid-induced Gastric Ulcer in Mice.
Investigation of the Effect of Loxoprofen-Na in Experimental Adjuvant-induced Arthritis in Rats Using Digital Microradiography, Macro-, and Microautoradiography.
A 13-week Repeated Oral Dose Toxicity Study of AY4166 in Beagle Dogs(Revised Report).
A 12-month Repeated Oral Dose Toxicity Study of AY4166 in Rats. Revised Report.
A 12-month Repeated Oral Dose Toxicity Study of AY4166 in Beagle Dogs. Revised Report.
Reproductive and Developmental Toxicity Study of AY4166 in Rats Administered Orally Prior to and in the Early Stages of Pregnancy. (Seg.I). Revised Report.
Reproductive and Developmental Toxicity Study of AY4166 in Rats Administered Orally during Fetal Organogenesis. (Seg.II). Revised Report.
Reproductive and Developmental Toxicity Study of AY4166 in Rats Administered Orally during the Perinatal and Lactation Period. (Seg.III). Revised Report.
8
Monitoring of the trial case and present state of the audit and problem. With the aim of new drug examination system in the twenty-first century.
Monitoring of the trial case and present state of the audit and problem. Present state and problem of the acceptance in the medical institution.
Monitoring of the trial case and present state of the audit and problem. Present state and problem of the acceptance in the medical institution. Present state of the medical institution ( from the trial case responsibility doctor ).
Monitoring of the trial case and present state of the audit and problem. Present state and problem from the viewpoint of the enterprise. From the enterprise in Japan.
Monitoring of the trial case and present state of the audit and problem. Present state and problem from the viewpoint of the enterprise. From the foreign-affiliated company.
Monitoring of the trial case and present state of the audit and problem. The summary of Ministry of Health and Welfare research team.
Comparison of Pharmacological Effects of Anti-inflammatory and Analgesic Transdemal Therapeutic Flurbiprofen Plaster with Ketoprofen and Indomethacin Plasters.
Effects of Butyric Acid Bacteria on the Loose Stools of the Helicobacter pylori Eradication.
Oral Mucosa Irritation Studies of Hamsters and Gastric Mucosa Irritation Studies of Rats.
Stereoselective Pharmacokinetics of Esonarimod(KE-298), A Newly Developed Antirheumatic Drug, in Rats.
Pharmacokinetics of the Antiviral Agent, Famciclovir.
Study on Potential Interactions of Famciclovir with Methotrexate and 5-Fluorouracil.
Study on Potential Interactions of Famciclovir with Anticancer Agents.
Clinical Evaluation TY-14(Excive 100) Spray in Treating Tinea Pedis and Tinea Glabrosa.
Clinical Evaluation of TY-14(Excive 100) Solution in Treating Tinea Pedis and Tinea Glabrosa.
Clinical Evaluation of TY-14(Excive 100) Spray in Treating Tinea Pedis and Tinea Glabrosa.
Clinical Evaluation of TY-14(Excive 100) Spray in Treating Tinea Pedis and Tinea Glabrosa.
Clinical Evaluation of Excive 100 Solution in Treating Tinea Pedis and Tinea Glabrosa.
9
Single Dose Oral Toxicity, and Oral Mucous Irritation Study of Green Tea Extract.
Comparison of Oral Administration Schedule on the Antitumor Activity of Orally Administered CPT-11 Against L1210 Leukemia and Meth A Fibrosarcoma in Mice.
Effect of Anchu-san and Shakuyaku-kanzo-to Extract on Helicobacter pylori-induced Gastric Mucosal Inflammation and Delayed Ulcer Healing in Mongolian Gerbils.
The Binding Affinity of Azasetron Hydrochloride for Various Kinds of Receptors.
Inhibitory Effects of Alminoprofen on a Febrile Response to Yeast and on a Response to Interleukin-1.BETA. in Rats.
Effects of Lysophosphatidylcholine on Renal Hemodynamics in Isolated Perfused Rat Kidney, and Dilazep Attenuates the Effects Induced by Lysophosphatidylcholine.
A Pharmacokinetic Study of Aminofluid, a New Peripheral Parenteral Nutrition Solution: Distribution and Excretion of 14C-Glucose and 14C-Amino Acids by Peripheral Administration in Normal Rats.
Effect of Sodium Prasterone Sulfate on the Cardiovascular System in Anesthetized Female Beagle Dogs.
Effects of Injection Rate on Plasma Concentration of Prasterone Sulfate in Anesthetized Dogs.
Safety and Efficacy of Fasudil Hydrochloride in Combination with Sodium Ozagrel on Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage.
The Long-term Study on the Optimal Dosage and Effectiveness of Pilsicainide Hydrochloride in Patients with Premature Ventricular Contractions and Renal Dysfunction.
The Clinical Effect of Misoprostol on the Wide-spread Lesion of Oral, Gastrointestinal and Colonal Mucosa in Four Cases.
10
Test for Skin Sensitization Potential of Green Tea Extract.
Effects of Efonidipine Hydrochloride on the Glomerular Hemodynamics.
Identification of Human Cytochrome P450 Isoforms Involved in the Metabolism of Lomerizine Hydrochloride.
Diuretic Effects of Manidipine in Isolated Perfused Rat Kidney.
Antiinflammatory and Analgesic Activities of Felbinac Patch (SELSPOT).
Skin Irritability of Felbinac Patch (SELSPOT). Clinical Comparative Study versus Commercially Available Patch.
Clinical Study of SP-02 in Treatment of Gastritis.
Clinical Evaluation of Felbinac Patch (SELSPOT) on Osteoarthritis of the Knee. Clinical Comparative Study versus Commercially Available Patch.
Clinical Evaluation of Felbinac Patch (SELSPOT) on Post-Traumatic Disease. Clinical Comparative Study versus Commercially Available Patch.
Clinical Evaluation of Methylmethionine Sulfonium Chloride (MMSC) on Gastric Ulcer.
11
Repeated Dose Toxicity Study of Green Tea Extract in Rat.
Influence of Israpafant on Airway Clearance.
Efficacy of a Novel Ophthalmic Solution, SMA-AG1 on Experimental Models of Allergic Conjunctivitis.
Effects of Carbocisteine in Combination with Bromhexine HCl on Mucus Composition, Plumonary Surfactant and Mucociliary Transport in Experimental Airway Disease Models.
Pharmacological Studies of Juzentaihoto Extract Oral Liquid (KJ).
Anti-androgen Effect of Ingredient in Hair Regrowth Preparation.
Effectiveness and Safety of Long-term Ingestion of Soup Containing Wheat-albumin (Glucodesign) in NIDDM Patients.
12
Oral Absorption of Dequalinium Chloride in Dogs.
The Origin of Anti-atherosclerotic Effects of Elastase.
Questionnaire for Early Detection of Occult Anemia.
Safety and Growth-promoting Effect of Human Growth Hormone (JR-8810) on the Short Stature in Turner's Syndrome (A Revised Edition). Effects of Two Years of Growth Hormone Treatment.