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List of Jounal Titles
A to Z index of Journal Title. Choose a letter.
Jpn J Pharmacol
100
- Molecular Basis of Muscular Dystrophy and Therapeutic Strategies
- Glutamate receptors-dynamic structure and subunit-specific signaling
- Prostanoid receptors; from cDNA cloning to translational research
- Pharmacogenomics of opioid drugs
- Metabolic syndrome-pathogenesis and treatment strategy
- Self-renewal of neural stem cells and CNS-repair
- GABAB receptor-structure and function in alimentary tract
- Pharmacological basis of traditional medicine as curative polypharmacy in the 21st century
- Do drugs suppress lethal arrhythmias?
- In search of new chemotherapy for cancer using mouse models
- Schizophrenia and the mode of functions of the risk factors in neurons
- Structural and physiological plasticity of hippocampal mossy fibers
- Mitochondrial dysfunction and apoptosis in neurodegenerative diseases
- Visualization of intracellular Ca'2+' signaling
- Functional analysis of DISC1 and DYSBINDIN-candidate genes for schizophrenia-
- Susceptibility genes for schizophrenia and intermediate phenotype
- PACAP knockout mice: A new model for psychomotor dysfunction
- Investigating signal transduction and genes-to-behaviors pathways in psychiatric diseases
- Animal models of schizophrenia for the development of new therapies
- RNAi library using EPRIL technology
- Biochemical characterization of RNAi and miRNA pathways in drosophila
- Recent progress in RNAi drug discovery
- Selection of highly effective and target specific siRNA sequences for mammalian RNAi
- Recent advances in SLC22 organic anion transporters
- Effect of Pregnane X Receptor ligand on expression of organic cation transporter OCT1
- Functional analysis of human ABCC4/MRP4 transporter by multichannel LC-MS/MS
- Hepatic and intestinal transporters as drug targets
- Functional roles of nitrergic nerve innervating cerebral artery
- S-glutathiolation in nitric oxide signaling
- Mechanisms of nitric oxide production from dietary nitrite
- Rational design of novel fluorescence probes for various reactive nitrogen species
- Generation and functional evaluation of mice lacking all nitric oxide synthase isoforms
- Identification and characterization of putative species-specific transcripts and promoters using full-length cDNA resources
- Reverse proteomics based on the ORFeome construction in the fission yeast Schizosaccharomyces pombe
- University compound project
- Development of basal techniques for identification of specific binding proteins using affinity resins bearing bioactive compounds
- Development of an integrated database of drug sensitivity and gene expression for the molecular pharmacology of cancer
- System identification based on genome resources, genome information and high-throughput transfection technology
- Adenosine A2A receptor antagonists as novel non-dopaminergic therapy for Parkinson's disease: a potential mechanism of theanti-parkinsonian action
- Astrocyte-to-pericytes interaction mediated by P2 receptors; regulation of microcirculation in the CNS?
- Brain chemokine production through the glial purinergic receptor activation
- Role of factors upregulating P2X4 expression in the pathogenesis of neuropathic pain
- Purinoceptor modulation of potentiated synaptic transmission in the central amygdala of the rat with neuropathic pain
- Endocrine disruptors and LD/ADHD/autism spectrum disorders; PCBs and other environmental chemicals are possible causal factors of the developmental disorders through disruption of gene expressions
- Effect of environemntal chemicals on neurobehavioral functions-experimental and field approaches
- Effects of organo-arsinic compounds on central nervous systems
- DES may have a definitive time window for producing brain disrupting actions in mice
- Dynamic changes in dopaminergic neurotransmission induced by a low concentration of bisphenol-A in neurons and astrocytes
- Influences of environmental estrogenic chemicals on catecholamine synthesis
- Regulation of histamine signaling-related gene expression in allergy
- Regulation of allergic airway inflammation through toll like receptor 4-mediated modification of mast cell function
- Signal regulation for distinct mast cell responses through Fc .EPSILON. RI
- Systemic approach to mast cell biology in allergic diseases
- The role of histamine in allergic reactions from the study of histidine decarboxylase gene-knockout mice
- The role of histamine in goblet cell hyperplasia in the murine asthma model
- New fluorescent probes and new perspectives in pharmacological science
- Toward functional imaging of whole living organisms
- Functional analysis of cell-cell repulsion using surface reflection interference contrast (SRIC) and total internal reflection fluorescence (TIRF) microscopy
- Development of new technique for imaging living mice using fluorescent proteins
- Evaluation of the effect of hypnotics in a new sleep-disturbed rats
- Novel model mice for sleep disorders and their applications
- Juvenile SHRSP/Ezo, an animal model for AD/HD
- Altered amygdala neuronal circuits and enhanced fear response in dystrophin-deficient mice
- Novel therapeutic targets for antidepressants: a study on olfactory bulbectomized rats
- Identification of susceptibility genes for bipolar disorder and its potential applications
- Approach of in vitro study to evaluate the efficacy and safety of medicines
- Assessment of antioxidant property of drugs using electron spin resonance (ESR) spectroscopy
- Evaluation of neuroprotective drugs by electron spin resonance (ESR)
- Advantages and limitations of a new coculture system using small intestine- and liver-derived cells
- Current status of in vitro methods for safety evaluation of a chemical by industries
- Effects of medicine on rat cultured embryos
- Microglial contribution in neuropathic pain: Involvement of ATP receptors
- Regulatory role of prostaglandin terminal synthases in upper airway inflammation
- Roles of lymphocytic cholinergic system in regulation of lymphocyte function
- Regulation of innate immune response by inducible histamine: Analysis on mouse hepatitis model
- Development of anti-allergic drug by collaboration between the NPO BioGrid and SOSHO projects
- New generation of the in-silico screening method
- An in silico prediction system of the risk of drug-induced cardiac arrhythmia
- Biosimulation-assisted prediction of different outcomes of anti-platelet reagents and its demonstration in vivo
- Surveillance from the viewpoint of gender differences about the actual use of prescription drugs
- Sex-related difference of cytochrome P450 and its molecular mechanism
- Hormonal regulation of cytodifferention of branching morphogenesis and expression of retinoic acid receptor in fetal mouse submandibular glands
- Gender differences in allergic reactions
- Gender medicine and kanpo
- Plants as unique model systems to evaluate drug efficacy and to search new pharmacological targets
- Genetic dissection of neurodegenerative signals in Drosophila
- Analysis on the mechanisms of reproductive organ formation; model systems as mice, fish and chick embryos
- Behavioral genetics in C. elegans- the roles for the insulin/PI 3-kinase pathway in behavioral plasticity
- Molecular analysis of higher brain formation using ferrets
- Regulatory mechanism of Ca'2+'/calmodulin-dependent protein kinase I .BETA. 2
- Involvement of CaM kinase II in pathophysiology of Alzheimer's disease
- The role of Ca'2+'/calmodulin-dependent protein kinase II in epilepsy
- Expression and functional significance of Ca'2+'/calmodulin-dependent protein kinase I during neuronal development
- Regulation of the ASK1-p38 MAP kinase pathway by calcium signaling and its involvement in neuronal diseases
- Animal experiments recommented by Japanese Pharmacological Society (evaluation and decrease of pain) 1) Introduction
- Pharmacology of pains
- Evaluation and standard of pain, distress, and euthanasia
- Animal experiment ethics committee in Showa University
- Research animal facility inspection by the third party
- Regulatory mechanisms of alternative splicing of viral RNA identified by reverse chemical genetics
- Chemical biology on histone deacetylases
- Chemical probes which convert cellular biological events to chemical output
- In vivo molecular science toward new biofunctions and drug discovery
- Molecular mechanistic insights into the intramembrane proteolysis by .GAMMA.-secretase
- Development of chemical biology utilizing a screening system of affinity purification with nano size beads
- Chemical biology of retinoids: their structures and functions
- ODN-based molecular therapy for vascular diseases
- Self-regulatory system of angiogenesis in vascular endothelium
- Modulation of RLP-induced vascular inflammation during atherosclerosis
- Roles of the prostanoids in the cardiovascular system
- Roles of Na'+'/Ca'2+' exchanger NCX1 in cardiovascular diseases
- The essential role of membrane raft and its associated protein, Fyn, in Ca'2+'-sensitization of vascular smooth muscle contraction
- Role of G .ALPHA.12/13 in the development of heart failure
- Ligand identification and functional analysis for orphan GPCR GPR120
- Prostanoid receptors; Analyses of their functions by using the animal disease models
- Toward the development of new medicinal leads with selectivity for protein kinase C isozymes
- Diacylglycerol kinase as a target of drugs for anti-diabetic renal dysfunction
- Nuclear IkB proteins regulate activity of innate immunity and intestinal inflammation
- TNF .ALPHA. directly suppresses smooth muscle contractility through CPI-17 down-regulation in intestinal inflammation
- Structure and function of capsaicin receptor TRPV1, and its involvement in gastrointestinal hyperalgesia
- Physiology and pathophysiology of proteinase-activated receptors (PARs) in the gastrointestinal tract
- Increased gastrointestinal toxicity of non-steroidal anti-inflammatory drugs (NSAIDs) in arthritic animals
- The role of Semaphorin in axon guidance and dendritic growth and spine morphogenesis
- Dynamism and regulation of synaptic assembly in vivo
- mTOR-mediated mechanism of local activation of translation in dendrites: Its implication for neural plasticity
- Dynamics of PSD molecules in glutamatergic synapses
- Formation and dynamics of neural networks in the hippocampal formation
- PPAR .GAMMA. ligand pioglitazone as a therapeutic strategy in nonalcoholic steatohepatitis
- PPAR .DELTA. and metabolic syndrome
- Decreased PPARs activity mediated inability of cell adhesion and invasion in colorectal carcinoma cells
- KATP channel-independent pathways involved in glucose-induced insulin secretion
- L-cysteine metabolism and hydrogen sulfide (H2S); a new signal pathway for inhibition of insulin release
- Sox6 attenuates glucose stimulated insulin secretion by repressing pdx1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice
- Intractable progressive neural diseases; Recent studies and therapeutic strategies
- ALS research: Fruit and perspective
- Multiple sclerosis: Pathogenesis and therapeutic strategy
- Molecular targeted therapy for polyglutamine disease with special reference to SBMA
- Progress in the research and neurotherapeutics for Parkinson's disease
- Metabolism of amyloid-.BETA. peptide and Alzheimer's disease
- Cyclic ADPR as a second messenger in peptide signal transduction
- Roles of calcitonin gene related peptide in maintenance of gastric mucosal integrity and healing process of ulcer
- Central feeding regulation by using mice lacking for NPY receptor subclasses
- Role of insulin signalings as a modulator of neurogenesis and neuroprotection: Regulatory mechanism of Na'+' channel expression by insulin
- Cardioprotective effects of kallikrein-kinin system
- Human sleep disorders and clock genes
- Chronopharmacological findings of antitumor drugs
- Role of biological clock in cardiovascular diseases
- Bronchial asthma and the function of human clock genes
- Role of circadian clock on hypercholesterolemia, obesity and diabetes
- Pharmacogenomics in drug metabolizing enzymes
- Interindividual variability of drug transporters
- Pharmacogenomics for pharmacodynamics, analysis of the inter-individual variability
- Individual differences based on adverse effects-related genes: Genomic analyses in clinical and non-clinical studies
- Use of animal models for genomic drug discovery
- Comparative pharmacogenomics of human disease model animal
- Translational control of .GAMMA.-secretase activity, augmenting amyloid-.BETA. production
- Endoplasmic reticulum (ER) stress and ischemic neuronal cell death
- Regulation of glutamate neurotoxicity by serofendic acid, a low molecular weight neuroprotective substance
- Nobiletin, a citrus flavonoid activating a PKA/ERK/CREB-dependent signaling pathway, rescues A .BETA.-induced memory impairment in Alzheimer's disease animal model
- Effects of Chotosan to related vascular dementia
- Current progress in the diagnosis and treatment of dementia
- Dysfunction of AQP5 in parotid of diabetes
- Diabetic stress and protective function in salivary gland
- Drug excretion in salivary glands: Clinical pharmacokinetic application and involvement of transporters
- Electrolyte transport and evaluation of secretory function in salivary glands
- Marker protein of salivary glands and functional diagnosis
- Molecular imaging of free radical reactions in small animals using Overhauserenhanced MRI and ESRI
- Molecular imaging of drug targets
- Development of PET probes for in vivo amyloid imaging and its clinical application
- Molecular imaging studies in rodents with PET
- Early postnatal stress alters the serotonergic function underlying regulation of emotional stress at postadolescent periods of rats
- Effect of Ginkgo biloba extracts on activation of ERK/MAP kinase in the rat hypothalamus after forced swimming test
- Possible involvement of the cortical GABAergic system in hippocampal synaptic responses in juvenile stress model of rats
- Effects of diabetes on freezing behavior and 5-HT release in the mPFCx under stressful condition in mice
- 5-HT7 receptors play a critical role in fear conditioning in mice: possible involvement of amygdaloid ERK pathway
- Balloon injury up-regulates the expression of proteinase-activated receptors and induces vasospasm at the injury site in rabbit femoral artery
- Pharmacological properties of T-7461, a new dual AT1 receptor and L-type calcium channel blocker
- Differential contribution of Rhokinase and protein kinase C isoforms to pressure-induced myogenic constriction in rat posterior cerebral arteries
- Mechanisms underlying the impaired EDHF-type relaxation in mesenteric arteries from diabetic rats
- Relaxin relaxes rat myometrium by decreasing Ca'2+' sensitivity of contractile apparatus via a cAMP/PKA signaling pathway
- Role of membrane phospholipids in the intracellular trafficking of CFTR
- Investigation of mechanisms mediated by PPAR .GAMMA.-inhibition on anti-tumor effect in various carcinoma cell lines
- Lipid metabolism of ICR background Clock mutant mouse under high fat diet
- Regulation of insulin receptor substrate-2 expression by calcineurin activity
- The enhancement of chemotherapy sensitivity by cathepsin E
- Behavioral pharmacology of plant-derived substances (15): Effects of menthol on extracellular dopamine, serotonine, norepinephrine and their metabolites in mouse striatum. Comparison with effects of bupropion, methylphenidate and caffeine.
- A possible involvement of non-enzymatic metabolites of DOPA in DOPAergic responses
- Tyrosine hydroxylase in dopaminergic nerve terminals projecting to the lateral region of the striatum is the most sensitive to tetrahydrobiopterin insufficiency
- Effects of repeated administration of rotenone and MPTP on CNS dopaminergic system in mice
- Deprenyl protected neural damage partially but showed marked attenuation of parkinsonism in MPTP-treated common marmosets
- Osteopontin has a prominent role in the intracellular signaling in osteoclast migration and fusion
- Involvement of glycosphingolipids in LPS mediated survival of mature osteoclasts
- Changes in bone density and metallothionein mRNA expression in the tibiae of ovariectomized rats
- Effect of PDGF on restoration of the support function of healing periodontal ligament in replanted rat teeth
- 18 .ALPHA.-glycyrrhetinic acid inhibits the growth of nifedipine responder cell
- Supraspinal pituitary adenylate cyclase-activating polypeptide (PACAP) exhibits antinociception mediated by the noradrenergic neurons in the central nervous system
- Possible mechanisms of induction and maintenance of intrathecal ATP-elicited long-lasting allodynia in rats
- Modulation of nociceptive transmission by mevalonate in the mouse spinal cord
- Activation of cytosolic phospholipase A2 in sensory neurons of a neuropathic pain model
- The role of ATP receptor subtypes on the painful diabetic neuropathy in mice
- Differential mechanisms of bradykinin-induced vasodilation in retinal and peripheral blood vessels of rats
- Transplantation of angiotensin type 1a knock out bone marrow cells inhibit tumor-associated angiogenesis and tumor growth
- Recruitment of a prostaglandin E receptor subtype, EP3-expressing bone marrow cells is crucial in wound healing and angiogenesis
- M-1, a major metabolite of sarpogrelate, has an inhibitory effect on not only 5-hydroxytryptamine (5-HT)'2A' but also 5-HT'1B' receptors-mediated vasoconstriction in isolated human radial artery and saphenous vein
- Difference in mechanisms of 5-hydroxytryptamine- and U46619-induced vasoconstrictions
- Regulational analysis and its signalling pathway of the mouse gicerin gene
- Involvement of endoplasmic reticulum stress in neuronal death after transient forebrain ischemia in gerbils
- Ketamine inhibits desensitization of GABAB receptor-mediated signaling through interaction with GRK4
- Physiological increase in extracellular calcium concentration evokes an increase in cytoplasmic calcium concentration via L-type calcium channels in human hyperparathyroid cells
- Analysis of the target gene encoding in zebrafish S100A1 for heart disease
- Studies on drug dependence (Rept. 419): Role of orexin neuron located in ventral tegmental area in the morphine-induced rewarding effect
- Study of neuropathic pain mechanisms I-preemptive analgesia by morphine
- Studies on pain control system (Rept. 51): Chronic pain-induced emotional dysfunction is associated with cortical .DELTA.-opioid receptor dysfunction-dependent astrogliosis
- The chronic morphine treatment increases the contents of D-serine in rat brain by regulating the mRNA and protein expressions of serine racemase and D-amino acid oxidase
- Involvement of the endogenous opioid peptide on the antinociception induced by endomorphin-2 in the mouse spinal site
- Development of novel tooth bleaching agent using electron spin resonance (ESR) spectroscopy
- Nitrogen-containg bisphosphonate, YM529 inhibits RANKL expression in bone marrow stromal cell line ST2
- The role of cathepsin E in tumor progression
- Application of software to simulate pharmacokinetics in practical training of pharmacology for undergraduate dental students
- Imaging of extracellular glutamate dynamics in brain slices
- Role of 5-HT1A receptors in fluvoxamine-induced suppression of marble-burying behavior in mice
- Foxy Methoxy, N,N-diisopropyl-5-methoxytryptamine, a selective inhibitor of serotonin transporter
- Muscarinic agonists enhance DNA synthesis via endoplasmic M1 receptor
- Metabotropic glutamate receptor-mediated postsynaptic inositol 1,4,5-trisphosphate signaling is required for the maintenance of presynaptic function of parallel fiber-Purkinje cell synapses
- High glucose-induced enhancement of endothelial cell permeability is involved in an increase of endothelial cell contraction
- Leukemia inhibitory factor induces endothelial differentiation in cardiac Sca-1+ stem cells
- Organization of cultured smooth muscle cells into vessel-like structure by endothelium-derived factor(s)
- Mechanisms underlying enhanced vasodilator responses to various vasodilator agents following endothelium removal in rat mesenteric resistance arteries
- Eplerenone, a selective mineralocorticoid receptor antagonist, inhibits cyclic stretch-induced NADPH activation through Nox1 in rat aortic smooth muscle cells
- Engineering of ligand-binding domain of the FRET-based prove LIBRA for tuning affinity for inositol 1,4,5-trisphosphate
- Different Ca'2+' dependence of CICR activity in ventricular and atrial muscles from swine
- Involvement of inositol 1,4,5-trisphosphate signaling in glucose-induced Ca'2+' responses in INS-1 .BETA.-cells
- Ca'2+' mobilization via ryanodine receptor type 2 in urinary bladder smooth muscle
- Roles of ryanodin receptor in rate capability of beating ventricular myocytes in culture
- Inward rectifier K'+' channel regulates cell death in bovine capillary endothelial cells
- The role of TARP .GAMMA.-8 (DVCC .GAMMA.-8) in AMPA receptor localization and function in hippocampus
- Effects of glutamate receptor antagonists on radiation- or chemotherapy-induced emesis
- Altered desensitization profiles of the .ALPHA. 7 nicotinic receptor with G423S mutation identified in a patient with schizophrenia
- Developmental change in the calcium channel subtypes involved in the excitatory and inhibitory synaptic transmission onto cholinergic neurons in the rat basal forebrain
- Effects of iNOS inhibitors on asthma depending on administration schedules
- The mechanism for the inhibitory effect of H3 agonist, Sch50971 on nasal symptoms of chronic rhinitis model in mice
- Protection against bleomycin-induced lung injury by p38 .ALPHA. knockout mice
- Integration of in vivo safety pharmacology core battery studies
- The role of PGD2 in sneezing and nasal rubbing induced by histamine in rats
- Serofendic acid protects nigrostriatal dopaminergic neurons in 6-hydroxy-dopamine rats
- Effect of glutamate receptor and dopamine receptor on place aversion induced by naloxone in single-dose morphine-treated rats
- Studies on drug dependence (Rept. 416): Site specific modulation of astrocyte-related soluble factors in the development of rewarding effects induced by drugs of abuse
- Chondroitin sulfate E promotes the neurite outgrowth of dopaminergic neurons through phospholipase C-mediated signaling
- Effects of dopamine receptor ligands on locomotor activity of mutant mice lacking NMDA receptors selectively in the neostriatum
- Infarct size-limiting effect of adrenomedullin is mediated by the opening of mitochondrial Ca'2+'-activated K'+' channels
- Anti-sympathetic property of L/N-type Ca'2+' channel blocker cilnidipine assessed in the halothane-anesthetized canine model
- Spatiotemporal analysis of shear stress-induced calpain activations in cultured human umbilical vein endothelial cells
- Roles of Na'+'/Ca'2+' exchanger in the regulation of myogenic tone in mice
- Conducted calcium responses to local KCl application in terminal arterioles from rat mesentery
- .BETA. 2-adrenergic regulation of the phosphorylation of ERK in human osteoblasts
- Differentiation-inducing factor-1 suppresses alkaline phosphatase gene promoter through the TCF/LEF binding site in SaOS-2 cells
- Establishment and characterization of clonal cell lines derived from miniature swine periodontal ligament
- Regulation of human osteoblast differentiation by vitamin D
- Effects of extracellular ATP on cultured fibroblast-like cells from human cervical ligamentum flavum
- Tissue-type plasminogen activator enhanced the permeability of blood brain barrier
- Assessment of antioxidant property of intravenous anesthetics using electron spin resonance (ESR) spectroscopy
- An oligodendrocytes-specific marker, monoclonal antibody Rip, recognizes 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase)
- Identification and characterization of a novel FK506 binding protein that interacts with Plexin-A4
- Analysis for molecular interaction of contactin associated protein (Caspr)2 in central nervous system
- Involvements of muscarinic receptors in electrical field stimulation-induced contraction of the mouse ileum
- The functional interaction between SK2 channel and nicotinic ACh receptor in enteric neurons of guinea pig ileum
- Prophylactic effect of Lactobacillus casei strain Shirota on NSAID-induced small intestinal damage
- Regulatory mechanism of capsaicin-induced gastric HCO3'-' secretion: Involvement of sensory neurons, nitric oxide (NO) and prostaglandins (PGs)
- Identification of prostaglandin E receptor subtypes relevant to gastric mucosal protection; a study using intravital microscopy
- CCKergic activation of orexin neurons via the CCKA receptor
- Modanifil activates the histaminergic system through the orexinergic system
- Effect of pituitary adenylate cyclase activating polypeptide (PACAP) on the tight junctions of the blood-brain barrier (BBB)
- Adrenal A and NA cells and celiac sympathetic neurons were separately controlled by centrally administered arginine-vasopressin (AVP) and corticotropin-releasing factor (CRF) in rats
- Antidepressant-like effect of .KAPPA.-opioid receptor agonist on learned helplessness model of depression in mice
- A mechanism of sex-related differences in QT intervals: HERG channel blockade by estrogen
- Inhibition of aldose reductase improves myocardial reperfusion injury by a dual mechanism
- Cardiac expression of mineralo-corticoid receptor contributes to cardiac remodeling after myocardial infarction
- Application of the first principle analysis to evaluate cardiac adenylyl cyclase stimulators
- The functional significance and mechanisms of nucleo-cytoplasmic shuttling of SIRT1 in failing hearts
- Role of hydrogen sulfide as a novel endogenous nociceptive messenger
- Immunohistochemical study of the GABAergic system in the mechanism of salivary secretion
- Facilitatory effect of hepatocyte growth factor (HGF) on redistribution of perivascular nerves in the rat mesenteric artery
- A potential therapeutic target and drug for de-myelinating disease in the peripheral nervous system
- Chronopharmacological treatment with dexamethasone and salbutamol using nebulizing resets the circadian change of clock gene in OVA-sensitized asthmatic mice
- Targeted DNA transfection into the mouse central nervous system using nanosecond pulsed laser-induced stress wave
- Neuronal circuits involved in the sensorimotor gating in mice
- Abnormal anxiety-related behavior in GPR7-deficient mice
- Generation of adenosine A3 receptor functionally humanized mice for the evaluation of the human antagonists
- Development of an in vivo animal model to monitor the extracellular neural amino acid in brain during behavior disorder at acute liver failure
- Inhibitory effects of statins on catecholamine secretion from adrenal chromaffin cells
- Role of Rho kinase in aldosterone-induced renal injury
- Role of reactive oxygen species and ERK in injury of LLC-PK, cells exposed to cisplatin
- Altered nitric oxide synthase (NOS), arginase and ornthine decarboxylase (ODC) activities and polyamine biosynthesis in response to ischemia of rabbit detrusor
- Effect of propiverine on neurogenic detrusor overactivity in spinal cord-injured rats
- Neuroprotective effects of a novel vasoactive intestinal peptide derivation on ischemic cerebellar granule cell cultures with astrocytes
- Molecular mechanisms of selective dopaminergic neuronal loss caused by mutation of PINK1, a causative protein in autosomal recessive Parkinsonism
- FKHR is dephosphorylated by calcineurin in mouse brain ischemia and its potential role in the neuronal death
- Altered gene expressions in rat hippocampus after kainic acid injection with or without manganese complexes of curcumin and diacetylcurcumin
- Hepatocyte growth factor protected hippocampal neurons after transient fore-brain ischemia by preventing translocation of apoptosis-inducing factor into the nucleus
- Determination of the prostaglandin F2.ALPHA.-response element in the promoter region of the NOX1 gene
- Chymase inhibition prevents the progression of abdominal aortic aneurysm in dogs
- Human cardiac failure model of zebrafish
- .ALPHA.-Lipoic acid reduces neointima formation after balloon injury in carotid artery of rats
- Cordycepin (3'-deoxyadenosine) inhibits platelet aggregation by stimulating adenosine receptors
- PGE2 receptor EP1 enhance Th1 differentiation
- Deficiency of c-Jun N-Terminal Kinase-1 enhances IL-10 production in macrophages
- The physiological significance of diacylglycerol-activated TRPC3 channels in B cell receptor signalling
- Anti-heat shock protein 70 anti-body production in sera of patients with rheumatoid arthritis
- Carrier effect of p47'phox' and p40'phox' in activation of Nox2
- Differential identification of mast cells and basophils increased in the lung in a murine model of asthma
- Changes of nasal blood vessels in thromboxane (TX) A2 mimetic, U46619-induced nasal blockage in a guinea pig model of allergic rhinitis
- Contribution of anaphylatoxin C5a to allergic inflammation in human lungs
- Suppression of allergic inflammation by the prostaglandin E receptor subtype EP3
- Identification of the regulatory elements involved in the intracellular localization of TLR3 and TLR7
- Neuroprotective effects of acetyl-cholinesterase inhibitors used in treatment of Alzheimer's disease against glutamate-induced apoptosis via nicotinic acetylcholine receptors
- Involvement of the cortical dysfunction of dopaminergic and glutamatergic signaling in the impairment of latent learning in mice treated with phencyclidine repeatedly
- Effect of Colivelin on Alzheimer's disease-relevant insults
- Angiotensin II Type 2 receptor stimulation enhances neural differentiation and attenuates cognitive decline after focal cerebral ischemia through MMS2-induction
- Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse
- Can natural vanadium-containing Mt. Fuji ground water improve glucose intolerance?: morphological and molecular experiments using KK-A'y' mice
- Amelioration of STZ-Induced diabetic rat nephropathy by n-hexacosanol
- Involvement of increase in intra-cellular calcium concentration and PKC .ALPHA. activation in LLC-PK1 cell injury induced by zinc
- Molecular identification and functional characterization of a novel Organic Anion Transporter OAT9 that is expressed in brain and kidney
- Inhibitory effect of adiponectin on PDGF-induced migration and proliferation in rat mesangial cells
- Study of neuropathic pain mechanisms III-Lysophosphatidic acid (LPA)-induced demyelination in explant culture and its mechanisms
- The role of prostacyclin receptor in mouse collagen-induced arthritis
- The activation of TP thromboxane A2 receptors induces itch-associated responses in mice
- Involvement of enteric glial COX-PGE2 pathway in responses of cultured rat myenteric neurons to bradykinin
- Regulatory mechanism of gastric hyperemic response after barrier disruption: roles of prostaglandin (PG)/EP receptor subtypes and sensory neurons
- Influence of cytokines on CD20 expression and Rituximab-induced CDC on MC/CAR myeloma cells
- SLURP-1 and SLURP-2 gene expression patterns in C57BL/6J mice
- Autoantibody epitope mapping on human prolactin (PRL) molecule in macroprolactinemia
- Effect of statins on immune response in monocytes
- Hyperhomocyseinemia (Hcy) increases the expression of inflammatory cytokines in retina of streptozocine (STZ)-induced diabetic rats
- Fibronectin upregulates expression of P2X4 receptors in microglia
- GABAB2 receptor subunit in heterodimerized GABAB receptors selectively transduces signal via the GABAB2 receptor-associated G proteins
- Differential roles of Ca'2+'/calmodulin-dependent protein kinase I and IV on the dendritic development of hippocampal neurons
- Redox regulation of the calcium/calmodulin-dependent protein kinase
- Calcium imaging of neurons with an improved G-CaMP
- MAP kinases activated by stimulation of endoplasmic M1 muscarinic acetylcholine receptors (mAChRs)
- The degradation of NFAT5 is induced by doxorubicin and impairs cell viability in cardiomyocytes
- Epigallocatechin gallate, a major polyphenol in green tea, binds to cardiac troponin C and desensitizes cardiac muscle contraction to Ca'2+'
- A knock-in mouse model for dilated cardiomyopathy caused by .DELTA. K210 mutation in cardiac troponin T and its pathogenic mechanism
- Disordered-coagulation-associated gene silencing in septic rabbits using small interfering RNA (siRNA)
- Caveolae-dependent signaling pathway induced by endothelin but not angiotensin II receptors
- Activation of matrix metalloproteinase-9 by chymase after myocardial infarcion in hamsters
- Vascular esponses of yolk-derived peptides in rat mesenteric arteries
- Pitavastatin improves vascular dysfunction in insulin-resistant state by inhibiting NAD (P) H oxidase activity and uncoupled eNOS-dependent superoxide production
- Role of angiotensin II on superoxide production in rabbit cerebral resistance arteries following chronic administration of nitroglycerin in vivo
- Effect of TS-022, a newly developed prostanoid DP1 receptor agonist, on experimental pruritis, cutaneous barrier disruption and atopic dermatitis models in mice
- A new chronic itch model accompanied by skin lesions in hairless mice
- Effects of Kujin-Plus, a novel formula of traditional Chinese herbal medicine, on severe atopic dermatitis in 64 patients
- Ethanol intake aggravates itch-related scratching in special diet-fed hairless mice via indirect potentiation of peripheral itching sensation
- Interferon-.GAMMA. increases extracellular ATP hydrolysis through up-regulation of ecto-nucleoside triphosphate diphosphohydrolase 1 in J774 murine macrophages
- Effect of inhibitors of tetrahydrobiopterin (BH4) biosynthesis on vascular cell adhesion molecule-I (VCAM-I) expression
- TXA2 receptor blockade confers cerebroprotective effects through suppression of cerebrovascular inflammation
- Chronic nitroglycerine administration reduces hyperpolarization in endothelial cells of rabbit aortic valve
- Prevention of hyper-contractile response to thrombin by proteinase-activated receptor-1 antagonist in rabbit double subarachnoid hemorrhage model
- Comprison of polyglutamine-, tunicamycin- and thapsigargin-induced ER stress in PC12 cells
- The regulation of CaMKII .DELTA. autophosphorylation in progression of cardiac hypertrophy in ovariectomized rats
- Oxidized LDL receptor LOX-1 is involved in diet-induced acute lipid-deposition in mesenteric artery of SHR-SP
- Effect of pioglitazone on the high density lipoprotein expression in plasma of sucrose and high fat diet loaded spontaneously hypertensive hyperlipidemic rats
- Modification of medial cell dynamics by cyclosporine A and everolimus in murine carotid allografts
- Reversal of cardiac disease in CryAB R120G cardiomyopathy
- Cognitive enhancer nefiracetam recovered learning and memory functions through activation of CaM kinase II and PKC in the olfactory bulbectomized mice
- Effects of endomorphin-1 (EM-1) on impairment of learning and/or memory after blockade of glutamatergic system in mice
- CaM kinase I mediates hippocampal LTP via CREB and myosin light chain phosphorylation
- Frequency-dependent long-term potentiation of excitatory synapses in the mouse cerebellum regulated by nitric oxide signaling
- Facilitated cerebellar LTD and OKR adaptation in mice lacking Delphilin
- Vascular response induced by a SOD mimetic, tempol, in rat mesenteric resistance arteries
- A phytosterol saponin of ginseng root (ginsenonside) is a mechanism-specific activator of sex steroid receptors
- A critical amino acid residue responsible for calmodulin-dependent kinase II (CAMKII)-mediated activation of vascular receptor-operated Ca'2+' entry channel TRPC6
- Store-operated Ca'2+' entry in 3T3-L1 preadipocytes is not affected by cytoskeltal structure.
- Effects of 4 .ALPHA.-phorbol 12,13-didecanoate, a potent activator of Trpv4, on intracellular Ca'2+' concentration and membrane currents in rat aortic myocytes
- Analysis of gene expression in rat aortic smooth muscle cells after exposure to calcification medium
- Doxorubicin induces atrogin-1, a muscle-specific ubiquitin ligase through FOXO pathway
- Decreased intracellular Ca'2+' transients in cardiomyocytes from transgenic mice overexpressing cardiac Na'+'/Ca'2+' exchangers
- Identification and characterization of a novel renal prostaglandin-specific organic anion transporter (OAT-PG) structurally distinct from PGT
- Taurine/taurine transporter system contributes to cytoprotection and normal development in skeletal muscles
- Centrally administered histamine evokes the release of noradrenaline and adrenaline from adrenal medulla by brain thromboxane A2-and cyclooxygenase-1-mediated mechanisms in rats
- Assessment of the sensitivity to an antidepressant in calcium/calmodulin-dependent protein kinase IV-deficient mice
- The role of p38 in epileptic seizure
- Effects of antiepileptics on the changes of visual evoked potential induced by the lateral geniculate kindling in rats
- Effects of exposure of sexual hormones during suckling period on the emotional and sexual behaviors in mice
- Studies on pain control system (Rept. 47): Role of increased intracellular Ca'2+' observed in the spinal cord in the development of a neuropathic pain in mice
- Studies on pain control system (Rept. 50): Involvement of microglia in the ethanol-induced neuropathic pain-like state in rats
- Involvement of noradrenaline transmission within the bed nucleus of the stria terminalis in negative affective component of pain in rats
- Interaction of the endocannabinoid and glutamatergic system underlies relapse to methamphetamine seeking in rats
- Studies on drug dependence (Rept. 418): Implication of Neuronal Wiskott-Aldrich Syndrome Protein (N-WASP) in the methamphetamine-induced rewarding effect
- Mechanisms of pressor response induced by nitric oxide synthase inhibitor L-NAME in rats
- Alterations of intracellular calcium concentration and NO production in rabbit pulmonary artery endothelium after subarachnoid hemorrhage
- Are nitrite and nitrosothiols significantly involved in physiological regulation of hemodynamics?
- Inhibitory effect of endothelium-derived relaxing factors (EDRF) on agonist-induced excess vasoconstriction and the effect of aging in rat mesenteric resistance arteries
- Mechanisms of hypertention in 5/6 nephrectomized rats: possibile therapeutics
- The regulation of large conductance Ca'2+'-activated K'+' channel expressions brings spontaneous contractions in vas deference from castrated-rat
- Functional role of ATP-sensitive K'+' channels in nodal cells during hypoxia: reevaluation using Kir6.2-null mice
- Molecular properties of channel pore regions in native smooth muscle-type ATP-sensitive K'+' channels
- Effects of nicorandil on the transmural conduction slowing during ischemia in canine left ventricles
- Effects of novel compounds derived from DiCDHA on the human BK channel
- Semaphorin3A selectively facilitates the axonal transport of its receptor and intracellular signaling molecules
- Molecular analysis of the EphA1/ephrin system
- Regulation of insulin receptor cell surface expression by glycogen synthase kinase-3 .BETA. activity
- Roles of spontaneous Ca'2+' signals in astrocytes in neurite outgrowth
- Regulation of insulin receptor substrate-1/-2 expression by glycogen synthase kinase-3 .BETA. activity
- The involvement of endocannabinoid system in MDMA-seeking behavior ("craving to MDMA") in rats
- Studies on pain control system (Rept. 49): Changes in cortical .BETA.-aminobutyric acid (GABA) ergic system under the neuropathic pain-like state in mice
- Methamphetamine (METH) upregulates L-type high voltage-gated calcium channels (HVCCs) through ryanodine receptor activation in the mouse brains
- Studies on pain control system (Rept. 48): Involvement of a spinal JAK/STAT pathway in the development and maintenance of a neuropathic pain-like state in mice
- Inhibitory mechanisms of codeine on the excitatory synaptic transmission in second-order neurons of the nucleus tractus solitarius in guinea pig brainstem slices
- Role of eNOS and NADPH oxidase in development of diastolic heart failure (DHF)
- Effects of antihypertensive drugs on enhanced nitric oxide production in aortas of SHR/NDmcr-cp (cp/cp) rats, a new animal model of metabolic syndrome
- Ethanol rapidly increases endothelial nitric oxide
- Reversal by oligonol, an oligomerized plant polyphenol, of high glucose-reduced nitric oxide release in endothenal cells
- ODQ suppresses myocardial apoptosis induced by hypoxia-reoxygenation
- Passive stretching produces Akt- and MAPK-dependent augmentations of GLUT4 translocation and glucose uptake in skeletal muscles of mice: A novel pharmacological strategy for controlling glucose metabolism
- Membrane potential and current responses to carbachol in longitudinal smooth muscle cells of mice ileum genetically lacking M2 or M3 subtype of muscarinic receptors
- Calcium sensitization and myosin light chain kinase activation in smooth muscle contraction
- Down-regulation of intermediate conductance Ca'2+' activated K'+' channel in smooth muscle of voltage dependent Ca'2+' channel .BETA.3 subunit deficient mouse
- Cyclohexenonic long-chain fatty alcohol reverses diabetic induced dysfunction of ileum in the rat
- Desensitization of the GABAB receptors by GRK4 and GRK5
- Functional analysis of novel growth suppressor Amida
- Functions of the cytoplasmic tails (C-tails) of the human receptor activity-modifying protein (RAMP) components of CGRP and adrenomedullin (AM) receptors
- Exploring novel drug targets through the comprehensive analysis of human protein-drug interactions
- Differential mechanisms of various beta adrenergic receptor antagonists by pharmacogenomics and pharmacoinformatics study
- Involvement of adenosine in depression of spinal reflex activity during hypercapnic acidosis in isolated spinal cord of neonatal rat
- Calpastatin degradation through caspase-3 activation mediates neuronal death following microsphere embolism in rats
- Hydrogen sulfide protects neurons from oxidative stress
- Characterization of sulfur in the brain released as hydrogen sulfide
- The pH sensitivity of the human HCN3 channel
- Roles of cardiac .ALPHA. 1B-adrenoceptor on contractile functions: studies in .ALPHA. 1B-AR-deficient mice
- Synergistic interaction of neuropeptide Y-Y1 receptor and .ALPHA.1A-adrenoceptor on the contractile response in rat arteries
- Clathrin is essential for activation of G protein-coupled receptor kinases 2 (GRK2)
- G protein .BETA. .GAMMA. subunit is critical for ATP-induced NFAT activation in cardiac fibroblasts
- Proton mediates nicotine-induced adrenergic nerve-dependent and CGRPergic vasodilation in rat mesenteric resistance artery
- Transport of nicotinate by human organic anion transporter hOAT2 and its possible interaction with transport of salicylate
- Role of intracellular C-terminal domain of the catalytic subunit of system b'0,+' for its trafficking and the protein-protein interaction
- The role of the C-terminal domain in mouse .BETA.3-adrenoceptor signalling
- Apoptosis-inducing effect of mevastatin on HL60 cells and its mechanism
- PI3K/Akt/FOXO3a/p27Kip1 pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes
- Pimaric acid modulate voltagegated K'+' channels by binding its activation gate
- .ALPHA.-1A adrenoceptor (.ALPHA.1A-AR)-induced Ca'2+' entry was augmented by a receptor-associated protein, snapin
- Interdomain interaction within type 1 ryanodine receptor involves dysfunction of Ca'2+' release channel in malignant hyperthermia
- The effects of GFP-tags on the ryanodine receptor type 1/Ca'2+' release channel in skeletal muscle
- Cell-cycle dependent regulation of small-conductance Ca'2+'-activated K'+' channel activity in Jurkat T-lymphocytes
- Effect of ferulic acid on oxidative stress-induced memory deficits in mice
- A free radical scavenger edaravone ameliorates anxiety-related behavior after cerebral ischemia/reperfusion in rats
- Colivelin prolongs survival of an ALS model mouse
- Suppressive effects of amyloid .BETA.(A.BETA.) fragments, A.BETA. 20-29 and A.BETA. 31-35 on A.BETA.-induced neurotoxicity
- CNTF receptor .ALPHA./WSX-1/gp130 complex-mediated neuroprotection from Alzheimer disease-related toxicity
- Role of Ca'2+' waves from pulmonary vein-left atrium junction in atrial arrythmogenesis
- Significance of the Ca'2+'-induced inactivation of L-type Ca'2+' channels in the phase 3 repolarization of cardiac action potential
- The beat-to-beat variability of ventricular repolarization as a marker for predicting proarrhythmic potential of QT-prolonging drugs, assessed in the chronic atrioventricular block dog model
- Molecular determinant of differences in the voltage-dependence between L-type Ca'2+' channel Cav 1.2 and Cav1.3
- The intracellular mechanisms for the cardioprotective effects of SEA0400, a novel Na'+'-Ca'2+' exchanger inhibitor
- Leptin inhibits orexin-producing neurons through opening of KATP channel
- Effect of lutein and pycnogenol on lipid peroxidation in porcine retinal homogenate
- Roles of PI3K in superoxide production and chemotaxis in FMLP-stimulated rat neutrophils
- Differentiation-inducing factors reduce both the protein and mRNA expression levels of cyclic D1 through the activation of glycogen synthase kinase-3.BETA.
- Cytotoxicity of lidocaine-Necrosis associated with cell shrinkage-
- Role of Prokineticin 2 Signaling on the Neurogenesis of Adult Olfactory Bulb
- The vulval precursor cells of C. elegans supply Nertrin/UNC-6 for the proper axon guidance of HSN neurons
- Opposite regulation of insulin receptor substrate-1/-2 by heat shock protein 90
- Dimerization and quality control of insulin-like growth factor-I receptor by heat shock protein 90
- Attenuated phosphorylation of heat shock protein 27 is correlated with tumor progression in patients with hepatocellular carcinoma
- IFN-.GAMMA. potentiates anti-cancer effects of hyperthermia and chemotherapeutics through Hsp27 down-regulation
- Natural drug extracts for a nutritive-tonic drink, promote induction of long-term potentiation in rat dentate gyrus in vivo
- Presynaptic I1-Imidazoline receptors reduce GABAergic synaptic transmission in the striatum
- Morphine regulates excitatory neurotransmission evoked by glutamate in the thalamus
- Functional suppression of neuronal nicotinic acetylcholine receptors by dehydroepiandrosterone and its sulfate ester
- Effect of milnacipran, a serotonin norepinephrine reuptake inhibitor, on catecholamine synthesis in cultured bovine adrenal medullary cells
- Pharmacological characterization of functional P2 receptors in cultured rat pericytes; regulation of contractile responses
- The relationship between nicotinic acetylcholine receptors and the hemodynamics changes of spontaneously hypertensive rats during chronic cigarette smoke
- Comparison of the inhibitory effects of donepezil and cloperastine on the G-protein coupled inwardly rectifying K'+' (GIRK) channel-activated currents in rat dorsal raphe neurons
- A novel in vitro screening method for sedative and non-sedative histamine H1 receptor antagonists by use of an intact cell binding
- Involvement of Ca'2+'-dependent mechanisms in down-regulation of Gq/11 protein-coupled/Ca'2+'-mobilizing histamine H1 receptors
- Visualization of synaptic transmission by optical glutamate imagin
- Effects of cloperastine on the 8-OH-DPAT-induced single K'+' channel currents
- Facilitated glycine release by metabolic disturbances in the motoneurons
- Self-rewriting networks: Ongoing modification of functional connectivity in hippocampal CA3 networks
- Serotonin 5-HT1A receptor agonist properties of several antipsychotics determined by ['35'S]GTP .GAMMA. S binding assay in rat hippocampal membranes
- Effects of nicotine on neurogenesis and plasticity in hippocampus
- Carboxy terminal region differently regulates the functional expression of human norepinephrine transporter splice variants
- Long-term administration of citalopram decreases the extracellular noradrenaline levels with remaining the function of .ALPHA. 2-adrenoceptors in rat brain
- The central neurotoxicity of 1-bromopropane (1-BP), a substitute for chlorofluorocarbons: Studies on the effects caused by direct and subchronic exposure to 1-BP on hippocampal function
- Effects of benzodiazepine hypnotics and antihistamines on the sleep-wake cycle in sleep-disturbed rats
- Pharmacological profiles of a novel potent serotonin 5-HT2C receptor antagonist FR260010 in animal models of anxiety
- Effects of systemic psilocin on serotonin release in rat brain
- Effect of coadministration of sulpiride and fluvoxamine on in vivo acetylcholine release in rat prefrontal cortex
- High performance fluorescent glutamate probes for visualization of synaptic transmission
- Sevoflurane excites the locus coeruleus neurons
- Decreased activity of brain neprilysin causes cognitive impairment through an increase insynapse-associated A.BETA. oligomers
- Impairment of auditory-cued fear conditioning in rats with permanent occlusion of bilateral common carotid arteries
- Cognitive dysfunction induced by sequential injection of amyloid .BETA. and ibotenate into the bilateral hippocampus; protection by memantine and MK-801
- Effects of antidepressants in the forced swimming test: Studies on sex differences in mice
- Mice strain differences in forced swimmint test: DBA/2 mice are useful animal model
- Effect of postnatal noise stress on emotional and anxiety-related behavior and spatial learning in juvenile mice
- Novel PET probes for in vivo imaging of tau pathology in Alzheimer's disease
- Intereukin-1 receptor antagonist effects on neural and behavioral development in mice
- The behavior-pharmacological research on the usefulness of flunarizine in the Alternating Hemiplegia of Childhood
- Alterations in cognitive function in prepubertal mice with protein malnutrition
- An animal model of depression: Recoveries from reduction of 5-HT release in the amygdala and disturbance of circadian rhythm of activity induced by the chronic dexamethasone infusion in rats
- Partial reversal of ketanserin on prepulse inhibition (PPI) deficits in a neurodevelopmental model of schizophrenia
- Influences of stress on the hippocampal synaptic function in the freely moving rat
- Behavioral effects of isatin, an endogenous monoamine oxidase inhibitor, in a rat model of attention-deficit/hyperactivity disorder
- Behavioral effects of the early postnatal stress on emotional expressions in male and female rats
- Effects of methylphenidate on hyperemotional behaviors in olfactory bulbectomized mice in the hole-board test
- Involvement of BDNF in long-lasting antidepressant-like effect of electroconvulsive stimuli in rats forced swim test
- Repeat dexamethasone treatment induced the dysfunction of HPA axis depending on the dosing-time
- Discrete metabolic changes in the STOP gene knock out mice, a model of schizophrenia
- Effect of memantine, a therapeutic drug for Alzheimer disease, and MK-801 on neuronal and glial activity in rat brain regions
- Raloxifene and EGb761 suppress stress-induced memory impairment in ovariectomized rats
- Rosmarinic acid protects against memory impairments induced by acute i.c.v. injection of A.BETA.25-35
- Behavioral and neurochemical studies on a new redent model of ADHD
- Anti-immobility effect of fluvoxamine depended on the 24-hr rhythm of serotonin transporter
- Time-dependent alteration of responses of clock genes in PVN for glucocortcoids
- Behavioral and neurochemical alterations in sleep deprived adolescent rats
- Effects of (Z)-3-hexenol, a major component of green odor, on anxiety-related behavior of the mouse in an elevated plusmaze test and biogenic amines and their metabolites in the brain
- Influence of stress-loaded conditions on the effects of nonylphenol in exploratory and emotional behaviors in mice
- Change of AP-1 in brain of dexamethasone infusion rats
- Mechanism for the imipramine-induced seizures in amygdala-kindled rats
- Tissue type plasminogen activator facilitates NMDA-receptor-mediated retinal apoptosis
- Involvement of endoplasmic reticulum stress in retinal cell death
- The role of Na'+'/Ca'2+' exchanger in retinal cell death induced by N-methyl-D-aspartate
- Cilnidipine reduces neuronal cell death induced by intravitreous injection of NMDA in the rat retina
- All-trans retinoic acid reduces neuronal cell death induced by intravitreous injection of NMDA in the rat retina
- Neuroprotective effects of sirtuinactivating polyphenols in mesencephalic slice cultures
- Nitric oxide protects microglia from hydrogen peroxide-induced apoptosis
- Characterization of 4-hydroxynonenal-induced cell death using various neuroprotective compounds in cerebellar granule neurons
- Distinct caspase is responsible for tunicamycin-induced ER stress in SK-N-SH and SH-SY5Y cells
- Involvement of caspases and DNase II in trimethyltin-induced damage of cortical neurons
- Zinc neurotoxicity and its relationship with calcium homeostasis
- Endoplasmic reticulum stress induces apoptosis through the activation of caspase-4 and -9 in human neuroblastoma SH-SY5Y cells
- Counteraction via P2Y1 receptor activation against the oxidative-stress-evoked death-inducing signaling in astrocytes
- Down-regulation of Cl'-' pump ClP55 subunit induced enhancement of glutamate neurotoxicity in cultured rat hippocampal neurons
- In vitro embryotoxicity assays by using mouse embryonic stem cells
- Facilitation of H2O2-induced A172 human glioblastoma cell death by stable expression of oxidative stress-sensitive TRPM2 channels
- Convulsions induced by glutamine synthetase inhibitors were inhibited by NMDA receptor antagonists and an nNOS inhibitor
- Neuroprotective effects of isoflavones as selective estrogen receptor modulators
- High mobility group box protein-1 enhances amyloid-.BETA. neurotoxicity
- Role of prokineticin-2 on kainic acid-induced excitotoxicity in mouse hippocampus
- Characterization of neurotoxicity induced by amyloid .BETA.-peptide and tunicamycin in organotypic hippocampal slice cultures
- Overexpression of megsin induces neuronal degeneration: Role of the endoplasmic reticulum (ER) stress
- The role of Na'+'/Ca'2+' exchanger (NCX) in seizure of mice
- Neuroprotective effects of dopamine D2 agonists on 6-hydroxydopamine-induced ER stress in the mouse brain
- Enhancement of sympathetic contraction by Sr-90 exposure in rat tail artery
- Effect of nicorandil on sympathetic neurotransmission in SHR/NDmcr-cp
- Inhibition of the serotonin-induced inward current by non-narcotic antitussives in rat nodose ganglion neurons
- Role of K'+' channels in prostanoid EP3 and TP receptors-mediated inhibition of noradrenaline release from the rat stomach
- Antinociceptive effect of camostat mesilate on pancreatitis-related pain in rodents
- Effects of SEA0400, a selective inhibitor of Na'+'/Ca'2+' exchanger, on Na'+'-dependent Ca'2+' uptake and catecholamine release in bovine adrenal chromaffin cells
- Occurrence and functional roles of estrogen receptors in the plasma membranes of bovine adrenal medulla
- Effect of simvastatin, a HMG-CoA reductase inhibitor, on catecholamine secretion in bovine adrenal medullary cells
- Pain is modulated by the interaction between the peripheral opioid and glutamate systems
- Atomic force microscopy revealed P2X2 receptor as a pore forming protein
- Effects of epigallocatechin-3 gallate, a green tea catechin, on the regulatory mechanisms of exocytosis in adrenal chromaffin cells
- Effects of local anesthetics on catecholamine secretion from bovine adrenal chromaffin cell
- Effects of various classes of inhibition of glycogen synthase kinase-3.BETA. on Semaphrion3A-induced facilitation of intraneuronal trafficking
- Cloning of the major quantitative trait locus underlying capsaicin resistance in mice
- Electrophysiological examination of analgesic action of capsaicin
- Inhibition of ATP-induced inward current by docosahexaenoic acid in rat nodose ganglion neurons
- Enhancement of parasympathetic activity by the application of heat- and steam-generating sheets to the eyes
- Effects of single and repeated administrations of KSS-694 (pilocarpine hydrochloride) on salivary secretion in MRL/lpr mice, a model for Sjogren's syndrome
- Difference in co-innervation rates of the esophageal striated muscle motor endplates: Does it mean different degrees of inhibition on vagally mediated contractions?
- Influence of enteric co-innervation on vagally mediated striated muscle contractions in mouse esophagus: Establishment of an in vitro investigation using sensory stiumulants
- Selective serotonin re-uptake inhibitors aggravate antral ulcers induced by indomethacin in rat stomachs
- Role of ion transporters on the recovery of wounds induced in gastric epithelial cells
- Establishment of highly purified chief cell cultures from the rat stomach
- Protective role of the endogenous gasomessenger hydrogen sulfide in rat gastric mucosa
- Inhibitory control of gastric acid secretion by vanilloid receptor TRPV1-expressing neurons in the mouse isolated stomach
- Effect of hydrogen sulfide, a gasomessenger, on gastric vascular tension and mucosal circulation in rats
- PACAP's role in the development of acute pancreatitis
- Protective effects of Kakkalide on ethanol-induced lethality and acute hepatic injury in mice
- Changes of inhibitor of apoptosis proteins (IAPs) expression during ischemia-reperfusion in rat liver
- comparison of mRNA levels of adult male-specific cytochrome P450 (CYP) isozymes in the liver of adult roof rats captured in environmentally distinct areas
- Bezafibrate improves non-alcholic steatohepatitis (NASH) in mice
- Zinc supplementation improves hepatic fibrosis induced by pig serum administration in rats
- Effect of dehydroepiandrosterone and aging on cytochrome P450 expression in rat liver
- Construction of a non-alcoholic steatohepatitis model induced by fatty liver and nitrite administration
- Angiotensin type 1 receptor antagonist accelerates liver regeneration by enhanced production of hepatocyte growth factor
- Tachykinin NK3 receptor-triggered serotonin release from guinea-pig distal colon
- 17.BETA.-estradiol induces gastrointestinal motility disorder by increasing Rho-family G-proteins, Rnds expression in ileal smooth muscle
- Effects of ghrelin peptides on contractility of isolated chicken gastrointestinal tracts
- Role of endogenous prostaglandins and cyclooxygenase isozymes in healing of indomethacin-induced small intestinal lesions
- Differential responses of the anal Inner sphincter and rectal smooth muscles to various drugs in the rat
- Fat absorption and postprandial hypertriglyceridemia of Spontaneously Diabetic Torii (SDT) rat
- The suppressing mechanism of interleukin-11 on radiation induced colitis in rats
- Effects of red wine vinegar beverage on the colonic tissue of rodents: Functional and biochemical analyses
- Orange juice decreases the expression of multidrug resistance-associated protein 2 in rat small intestine and liver
- Effect of folk medicine Bidens pilosa L. on hepatic drug metabolizing enzymes of rats
- Gastroprokinetic effects of Corydalis Tuber and its ingredients during the digestive state in mie
- Effect of Rikkunshito on gastric emptying in rats may be related to serotonergic nervous system
- The preventive effects of constituents of daikenchuto and its active components on the postoperative adhesive intestinal obstruction in rats
- A survey on medical education for Japanese traditional medicine (Kampo) in undergraduate curriculum: A student perspective
- Change of cytokines release by an antigen-presenting cell (APC) line during the cell maturation and nicotinic stimulation
- DU-176b, an oral and direct factor Xa inhibitor: In vitro pharmacological profile, pharmacodynamics, and antithrombotic effects
- Lineage-specific survivin induction by GM-CSF
- Rapid assay of mouse plasma catecholamine (CAs) by a simplified alumina-adosorption method using high-performance liquid chromatography with electrochemical detection
- GHHPH motif in histidine rich glycoprotein exerts anti-angiogenic effect independently of its binding to heparin
- Effect of reactive oxygen species (ROS) scavengers as (+)-catechin on methemoglobinemia
- Effects of Kurozu on risk factor of arteriosclerotic disease
- Binding of wortmannin to N.ALPHA.-acetyl lysine and N.ALPHA.-acetyl cysteine
- Effects of unpollished rice vinegar (Kurozu) on risk factor of life style diseases in human
- Possible roles of neuropeptide Y Y3 receptor in the rat aortic endothelial cell (RAEC) proliferation
- Transient ischemia induces structural damage of the rat retinal blood vessels
- Vascular tube formation of CD44+ CD90+ cells isolated from neurospheres
- Angiotensin type 2 receptor-dependent phosphorylation of eNOS in rat thoracic aorta after the abdominal aortic banding
- Angiotensin type 2 receptor stimulates eNOS production and phosphorylation in endothelial cells
- Region-specific impairment of endothelial function in rabbit cerebral arteries after long-term in vivo administration of nitroglycerin
- Regional differences in the production of epoxyeicosatrienoic acids among rabbit aortae, determined by LC/MS/MS
- Mechanisms underlying endothelium-dependent effects on the aorta of apolipoprotein-E-deficient mice
- New approach to estimate Ca'2+' response and vasoreaction of small artery employing real-time confocal microscopy
- Lipo-PGE1 accelerates ischemia-induced neovascularization in mouse hindlimbs
- Alteration of cell-to-cell connection under high-glucose condition in arterial endothelial cells
- Involvement of facilitated reendothelialization, decreased endogenous NOS inhibitor and restored NO generation with estrogen in improving the accelerated intimal hyperplasia following ovariectomy
- Effect of hyperglycemia without hyperinsulinemia on vascular responsiveness in pithed rats
- Basic fibroblast growth factor induces tetrahydrobiopterin synthesis through stimulation of Erk pathway in vascular endothelial cells
- Decrease in nitric oxide and increase in CYP2C9-derived arachidonic acid methabolites production in rabbit renal artery from short-term hypercholesterolemia
- Laminar shear stress induces cytochrome P4501A1 through the aryl hydrocarbon receptor-xenobiotic response element signaling pathway in vascular endothelial cells
- Nuclear factor-.KAPPA.B regulates endothelin-1 gene expression
- Effects of hypoxia on endothelin-1 production in cultured vascular endothelial cells
- Chronic nitroglycerine administration reduces endothelial nitric oxide production in rabbit mesenteric resistance artery
- Theaflavin-3,3-digallate inhibits tube formation
- Acute effect of elevated circulating free fatty acid levels on endothelial function in genetically obese rats
- Vascular dysfunction in the heritable hypertriglyceridemic rabbits
- Beneficial effects of cyclo-hexenonic long-chain fatty alcohol on STZ-induced diabetic rat aorta
- Detection of amyloidosis by BF-227, a ligand for amyloid A.BETA. fibrils
- Astaxanthin ameliorates features of metabolic syndrome in rat model SHR/NDmcr-cp (cp/cp)
- Relationship between PGE2 and VEGF on angiogenesis in human endothelial cells
- Adiponectin inhibits cell migration induced by insulin-like growth factor-1 in vascular smooth muscle cells
- Involvement of polyamine and proline pathway in initiation/development of intimal hyperplasia in premenopausal human uterine arteries
- NF-.KAPPA.B inactivation is involved in the mechanisms of sexual dimorphic response to atorvastatin against vascular injury
- Effect of condroitinase on the dermatan sulfate facilitated arginine amidase activity release from rabbit arteries
- Modification of Angiotensin II-induced contractions by bradykinin release via endothelial AT2 receptors in porcine basilar artery
- Apocynin normalize the abnormal vasomotor activities in mesenteric arteries from cholesterol-fed mice
- Possible involvement of Jak2-STAT pathway on the stimulation of tetrahydrobiopterin synthesis by hydrogen peroxide in vascular endothelial cells
- Bioimaging of caspase activation during ER stress-induced cell death
- Enhancement of sensitivity against cell death in mutated facal adhesion kinase transfected PC12 cells
- Induction of apoptosis and inhibition of telomerase activity by proposlis in U937 cells
- Modulation factors of tumor-specific cytotoxic activity of anthracyclines
- Application of semiempirical molecular orbital method for the estimation of structure and cytotoxic activity of butelinic acid derivatives
- Mechanism of apoptosis induced by rotenone
- Oligomerization of GAPDH via formation of the intermolecular disulfide is involved in irreversible inhibition of the activity by oxidative stresses
- Adenosine mediated signal transduction for the protection of apoptosis and the cell differentiation
- Implication of Phospolipase D1 in cell survival against pepsin-digested lactoferrin peptide(s)-induced apoptotic cell death in oral squamous cell carcinoma
- IP3 receptor-dependent Ca'2+' entry in DT40 cells
- Discovery of novel TRPC channel blockers
- Discovery of a novel modulator for insect ryanodine receptor
- Regulation of Ca'2+' mobilization by prolactin in mammary gland cells
- Differential intracellular signaling through cysLT2 receptor by cysteinyl leukotrienes
- Homophilic cell contact activated Rac1 and up-regulated p27'Kip1' transcription in vascular endothelial cells
- Identification of Par3 as a novel substrate of Rho-kinase
- Mastoparan inhibits Gs-mediated signal transduction through changing the localization of G.ALPHA.s in lipid rafts
- R9AP regulates RGS9-1 activity through its targeting to lipid rafts
- EGCG inhibits cancer cell growth through retinoblastoma protein
- Short time hypoxia stimulates cell growth in vitro
- The suppression of mTOR signaling pathway underlies the anti-tumor effects of LAT1 inhibitors
- Participation of hOat3 in acquirement of drug resistance against 5-FU
- U0126, a specific inhibitor of activation of extra cellular signal-regulated kinase, inhibited the proliferation of a human pancreastic cancer cell line, KP4
- Effects of branched-chain amino acids on DNA synthesis and proliferation in primary cultures of adult rat hepatocytes
- Increased expression of PAR-2 by bFGF in synovial fibroblasts derived from patients with rheumatoid arthritis
- Suboptimal amount of TNF-.ALPHA. potently suppresses osteoblast differentiation in slight acidosis
- Regulation of neurite extension mediated by neuronal calcium sensor-1 in nerve growth cone
- Anthraquinones suppress aryl hydrocarbon receptor transformation induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin
- Determination of histamine and '.TAU.'N-methylhistamine using HPLC-amperometry
- The regulatory mechanisms in cell surface expression of thromboxane A2 receptor
- Thromboxane A2 enhances IL-6 biosynthesis via CREB in 1321N1 human astrocytoma cells
- The role of N-terminal palmitoylation of Sonic hedgehog
- Mechanism of cPLA2.ALPHA. activation induced by tyrosine phosphorylation signal
- Comparative study of culture condition on CYP3A4 regulation in primary hepatocytes
- Development and application of a stable HeLa cell line capable of site-specific transgenesis by the Cre/mutant lox system-part I: Establishment and phenotype analysis of a human TNFRI knockdown cells
- Effects of polychlorinated biphenyls on cultured rat embryos
- Transport of methylmercury through the epithelial type amino acid transport system B'0'
- Structural determinants in the heavy chain subunits of heterodimeric amino acid transporters for recognition of light chains
- Increase of ADP uptake induced by 2-deoxyglucose in MDCK cells
- Effect of Boiogito on the cell membrane water permeability
- Opioid peptide evaluated from computational chemistry
- Characterization of brain cyclooxygenase involved in CRF-induced central activation of sympatho-adrenomedullary outflow in rats
- Central injection of hypertonic saline activates angiotensin II-sensitive neurons in the anterior hypothalamic area of rats
- Altered feeding behavior in mice lacking the V1a vasopressin receptor
- The localization of vasopressin V1B receptor in the mouse central nervous system
- Central NF-.KAPPA.B is involved in the CRF-induced central activation of sympatho-adrenomedullary outflow in rats
- Centrally applied GLP-1 activates the sympatho-adrenomedullary outflow by brain prostaglandin-mediated mechanisms in rats
- Effect of substance P(1-7) on the release of glutamate and nitric oxide evoked by intrathecal administration of capsaicin
- Molecular and pharmacological characterization of primate NK1 and NK3 tachykinin receptors in the central nervous system of the rhesus monkey
- Increase in galanin gene expression in hypothalamic dorsomedial nucleus by fasting
- Regulation of neuropeptide gene expression by fasting in NPY-Y1 receptor knock out mice
- Mapping of single amino acid residues required for G protein activation by the rat melanin-concentrating hormone receptor
- Studies on drug dependence (Rept. 417): Changes in .BETA.-endorphin (.BETA.-EP)-containing neurons in the process of less liability of morphine dependence under a neuropathic pain-like state
- Effects of lobeline on methamphetamine-induced stereotyped behaviors and brain monoamine turnover in mice
- Decreased striatal dopamine level accompanied by the increase in the duration of the stereotypy after treatment with 2-phenylethylamine in combination with l-deprenyl in mice
- Fluoxetine as a potential pharmacotherapy for methamphetamine dependence
- Effect of a selective 5-HT1A agonist tandospirone on abnormal involuntary movements in rat L-DOPA-induced dyskinesia model
- Proteomic study on brain disrupting actions caused by prenatal diethylstilbestrol exposure in mice
- Prostaglandin E2 potentiates D1R signaling via EP1
- Repeated exposure to methamphetamine elicits synaptic plasticity in rat mesolimbic slice culture
- Human dopamine transporter isoform produced by alternative splicing
- Non-enzymatic metabolites of DOPS can induce DOPAergic responses
- Amperometric detection and characterization of exocytotic events in single ventral midbrain dopaminergic neurons
- Activation of dopamine D4 receptors is protective against hypoxia-reoxygenation-induced cell death in HT22 cells
- The acute treatment of morphine augments the expression of serine racemase and D-amino acid oxidase mRNAs in rat brain
- Accumbal shell adrenoceptors differentially modulate dopamine and acethlcholine receptor-mediated turning behaviour
- Novel and potent poly (ADP-ribose) polymerase-1 inhibitors, quinazolinone and quinoxaline derivatives, ameliorate dopaminergic neuronal damage in mice models of Parkinson's disease
- Role of nitric oxide system in striatal hydroxyl radical production in carbon monoxide poisoned rats
- The role of histamine H3 receptors in reward and locomotor sensitization induced by psychostimulants in mice
- Effecf of nicotine on the priming stimulation effect of intracranial self-stimulation reward in rats
- Influence of amantadine and memantine on MAO activity, monoamine uptake and 5-HT-induced head-twitch response in mouse
- Double-transplantation of mouse embryonic stem cell-derived neurons and behavioral recovery in hemiparkinsonian rats
- The effect of entacapone, a catechole-O-methyltransferase inhibitor, on motor activity and striatal dopamine levels in a rat model of Parkinson disease induced by Japanese encephalitis virus
- The neuronal mechanism of ORL1 receptor agonist W-212393-induced nonphotic entrainment of circadian clock
- No effect of ORL1 receptor agonist W-212393 on light-induced phase shifts of circadian clock
- Role of serotonin2 receptors in methamphetamine-induced behavioral sensitization in mice
- Inhibition of D1-like dopamine receptor signaling by expression of the third intracellular loop domain of the D1 receptor
- SKF83959 regulates DARPP-32 phosphorylation by activating PLC-dependent and independent cascades
- Effect of cannabinoid receptor ligands on 3-nitropropionic acid-induced dopamine release in rat striatum
- Characterization of dopaminergic neurons in flatworm planarian and development to unique medicines
- Alteration of bradykinesia and striatal serotonin level in a rat model of Parkinson disease induced by Japanese encephalitis virus
- Role of DARPP-32 Thr34 phosphorylation in methamphetamine-induced behavioral sensitization
- Effects of thiotepa on the polyamine concentration in regional brain of rats
- P2Y6 receptor mediates the constitutive pinocytosis in astrocytes
- Modulation of P2 receptor-mediated signaling by lipopolysaccharide in rat astrocytes
- The identification of a microplatform that mediates K'+' and water transports in brain astrocytes
- Polysulfides induce calcium waves in rat hippocampal astrocytes
- Evaluation of pentosan polysulfate for the permeability of blood-brain barrier
- Inhibition of a glial K'+' channels by a tricyclic actidepressant, nortriptyline
- Protective effect of ATP on oxidative damage of astrocytes in rat hippocampal cultures
- Upregulation of microglial P2X4 receptors by retinoic acid
- .ALPHA.7 nicotinic acetylcholine receptors modulate microglial function via a phospholipase C/IP3 pathway
- Phosphorylation of MLC by Rho kinase is involved in lysophosphatidic acid-induced reversal of stellation in rat astrocytes
- Protection by antidiarrheic ingredients against cell death in cultured astrocytes
- Activation of microglia by subacute treatment with LPS leads to the decrine of NMDA receptors
- Effect of purine and pyrimidine nucleosides on basal and hydrogen peroxide-induced thymidine incorporation into cultured astrocytes
- Regulation of the blood brain barrier function with 17.BETA.-estradiol
- Glucose regulated blood-brain barrier transport of insulin: Pericyte-astrocyte-endothelial cell cross talk
- Quinidine blocks the astroglial inward-rectifier Kir4.1
- Hepatocyte growth factor (HGF) enhances barrier function of the blood-brain barrier (BBB)
- Nicotine improves short-term memory deficit induced by domoic acid, an amnesic shellfish poison, in mice
- Volatile female odors activate the accessory olfactory system of male mice without physical contact
- Participation in GABA neurons of the medial septal area on radial maze performance in rats
- Observation of drug-induced disruption of fine motor control in monkeys (2nd report)
- Effect of repeated valproate and diazepam treatment on contextual fear conditioning-induced behavioral changes in mice
- Safety pharmacological property of intrathecal baclofen in rats
- Behavioral characterization of the object location test in mice
- Antagonist of NMDA receptor attenuated jumping behaviors of PACAP-deficient mice
- Role of hippocampal extracellular signal-regulated kinase (ERK1/2) phosphorylation in spatial working memory
- Changes in cortical synaptic transmission during extinction of contextual fear in freely moving rats
- Role of Piccolo in long-term potentiation and spatial memory
- Vasopressin V1a receptor knock-out mice exhibit impairment of social behavior
- A possibility of cyclooxygenase participation in the NC-1900-induced improvement on learning and memory in mice
- Altered synaptic transmission in APPswe and PS1 double transgenic mice
- Mechanism of adenosine-induced hypothermia during entrance phase of hibernation in Syrian hamsters
- Inducible ablation of cerebellar granule cells by a CrePR-loxP recombination system
- Influences of epidermal growth factor (EGF) overexpression on mouse behavior
- Neurobiological basis of isolation induced-ultrasonic vocalization in a rat pup
- Fisetin, a flavonoid, facilitates the induction of long-term potentiation in the CA1 region of rat hippocampal slices and memory for object recognition in mice
- Effects of oral administration of crocetin on diazepam-induced impairment of amygdalo-hippocampal long-term potentiation and anti-convulsive action
- Mechanisms of enhanced excitation in mutant mice lacking NMDA receptors selectively in the hippocampal CA3 region
- Separation-induced ultrasonic vocalization in rat pups: Further pharmacological characterization
- Antidepressant and anxiolytic effects of a nonpeptidic MCH1R antagonist, ATC0218
- Effect of pyrilamine on the hippocampal theta wave during radial maze performance in rats
- Ameliorating effects of GLP-1 on lipopolysaccharide-induced memory impairment in mice
- Ethanol facilitates reconsolidation process in contextual fear memory
- Nobiletin with CRE-dependent transcription-stimulating activity improves MK-801-induced impairment of learning and memory in mice
- Role of NADPH oxidase in the pathogenesis of DOCA-salt-induced hyper-tension
- Augmentation of intrarenal angiotensin II levels in aldosterone-induced hypertensive rats
- Mechanism of the onset of diabetic nephropathy in type 2 diabetic db/db mice (1st report)
- Nephroprotective effect of Pioglitazone in Zucker fatty rats
- Changes of RhoA and RhoB proteins in ischemic acute renal failure
- Effect of agmatine in ischemic acute renal failure rats
- Preventive effect of moxonidine on ischemia/reperfusion-induced renal injury in rats
- Induction of the intestinal oligopeptide transporters in puromycin-induced nephrotic syndrome in rats
- Transdifferentiation of renal epithelial tubular cells induced by albumin-bound oleic acid
- Protective effect of cyclic AMP against cisplatin-induced nephrotoxicity
- Involvement of cholesterol in production of initial glycated amadori-protein
- Probenecid inhibits calcium oscillations in MDCK cells
- Roles of altered arginase activity and nNOS protein expression for the impaired neurogenic relaxation of carpus cavernosum in the aged rabbit
- Examination on benign prostatic hyperplasia in non-human primate
- Real-time monitoring of nitric oxide and blood flow during ischemia-reper-fusion in the rat testis
- Mechanism underlying the dimethyl sulfoxide (DMSO)-induced relaxation of the rabbit detrusor smooth muscle
- Temperature-dependent actions of flavoxate hydrochloride on voltage-dependent L-type Ca'2+' currents in human detrusor myocytes
- Actions of ZD0947, a novel ATP-sensitive K'+' channel opener, on membrane currents in human detrusor myocytes
- Urethral responses to electrical stimulation of pelvic nerve and capsaicin in male and female rats
- Investigation of conscious and unrestricted cystometry in mice
- The role of TRPV4 as a flow sensor in the fow-dependent K'+' secretion in the cortical collecting duct
- Transporter-mediated toxicity of cephaloridine and ochratoxin A assessed by DNA microarray analysis
- Inhibitory effect of resveratrol, a phytoestrogen, on catecholamine synthesis in cultured bovine adrenal medullary cells
- Effect of orchidectomy on sildenafil-induced flushing of tail skin in mice
- IGF binding protein-7 modulates steroidogenesis in ovarian granulosa cells
- Impaired glucose utilization in white adipose tissue of diet-induced obese mice and intervention using PPAR.GAMMA. agonist
- Expression of mRNA for APJ, an orphan GPCR, in adipose tissue of obesity-associated diabetic mice
- Mild electrical stimulation with hyperthermia up-regulates heat shock protein 72 expression and ameliorates hyper-glycemia in mice model of type 2 diabetic
- Analysis for functional roles of vasopressin receptors in releasing growth hormones
- Tissue distribution of L-cysteine-metabolizing enzymes possibly involved in the production of hydrogen sulfide
- A murine model of Graves' disease applicable to analysis for new anti-thyroid drugs and their evaluation
- Substrate recognition mechanisms of a novel cationic amino acid transporter CAT5
- Effects of angiotensin II receptor blockers on genetically diabetic mice
- Development of the simple and sensitive detection system for the estrogen-like substances used human cell culture
- Differential roles of 5-HT2 receptor subtypes on m-CPP-induced ejaculatory response in male rats
- Gestational changes in arginase activity for regulating myometrial contractions in the rat
- Participation of adenosine receptors in the ADP- and ATP-induced relaxations in the corpus cavernosum penis of rabbits
- Combination therapy of an ARB with a statin exerts additive cardioprotection through inhibition of reactive oxygen species in Dahl salt-sensitive rats
- In vitro and in vivo electrophysiological effects of D2 receptor antagonists in isolated ventricular myocytes and anesthetized guinea pigs
- Evaluation of effects of drugs regarding QT interval prolongation by ex vivo action potential duration assay
- Evaluation of Geldanamycin-induced blockade of hERG trafficking
- Geranylgeranylation of RhoB in Na'+'/Ca'2+' exchanger mRNA increase by lisophosphatidylcholine in H9c2 cells
- Olmesartan suppresses hypoxia-induced left ventricular remodeling in apolipoprotein E-knockout mice
- Effects of drugs affecting the QT-intervals on ECG recorded in dogs under anesthetic and conscious conditions
- Inhibitory effects of dronedarone and amiodarone on HERG+KvLQT1/minK currents
- Extracellular acidosis attenuates the ventricular repolarization delay by pharmacological IKr blockade assessed using the Langendorff-perfused guinea-pig heart
- Assessment of cardiac function using echocardiography in the rat
- Action potential properties of the myocardium from chronic AV block dogs (2): Atria and pulmonary vein
- Action potential properties of the myocardium from chronic AV block dogs (1): right ventricle and Purkinje fiber
- Effects of thiopental on muscarinic potassium currents in atrial cells from guineapig
- R(-)-efonidipine, a selective T-type calcium channel blocker, inhibits the progression of monocrotaline-induced right ventricular hypertrophy in rats
- Preventive effects of coenzyme Q10 against increased oxidative stress in rats with metabolic syndrome
- Modeling of the inactivation process of L-type Ca'2+' channel
- Reduction of myocardial infarct size by tetrahydrobiopterin: Possible involvement of mitochondrial KATP channels activation through nitric oxide production
- A novel monkey proarrhythmia model that can predict the drug-induced torsades de pointes in clinical practice
- Characterization of SN-6, a novel benzyloxyphenyl derivative Na/Ca exchange inhibitor
- Intracellular mechanisms for the endothelin-induced negative and positive inotropy in adult mouse ventricle
- Coassembly of KCNE1 alters the putative binding site of azimilide on KCNQ1 channels
- Cloning of novel isoforms of murine cardiac calcium channel .ALPHA.1 subunit and their different binding affinities with .BETA.2 subunit
- Facilitation of HERG channel can be induced by various HERG blockers
- Establishment of the cultivation system in sinoartrial node cells and maintenance of their genetic characters: Morphological changes and drug responsiveness
- Relationship between morphological change of the cardiomyocytes and intracellular calcium kinetics in doxorubicin-induced cardiomyopathy mouse model
- CaMKII and ERK activities mediate endothelin-1-induced cardiac hypertrophy in cultured rat cardiomyocytes
- Positive inotropic effect of EGCg, a green tea cathechin, in guinea pig hearts: The measurements of cellular Ca'2+' and NO release
- Protease activated receptor-1-mediated activation of focal adhesion kinase in rat cardiomyocytes
- S-nitrosylation of the slow activating delayed rectifier K'+' channel by nitric oxide
- Paradoxical effects of endothelin-1 on myofilament Ca'2+' sensitivity in twitch and tetanic contraction in mouse ventricular myocytes
- Crebanine inhibits the L-type calcium current (ICa,L) and the inwardly rectifying potassium current (IK1) in guinea pig ventricular myocytes: Relevance with antiarrhythmic action
- HTS screening of hERG blockers using 2nd-generation -automated patch-clamp system
- The effect of extracellular pH on the Ikr and its blockers
- In vitro safety pharmacology assay using guinea pig cardiac myocyte
- Effects of tanshinone VI on signal transduction in the facilitation of cardiac hypertrophy and fibrosis in vitro
- Modulation of hERG and potency of its blockers by lowering the extracellular potassium concentration
- Effects of imipramine on Ikr of hERG/HEK293,INa of isolated ventricular cells, and action potential of papillary muscle of the guinea pig
- Effect of freeze-dried red wine on the coronary circulation of rats with cholesterol-rich diet
- Effects of doxapram HCI on cardiac conduction system
- The usefulness of monophasic action potential and electrocardiogram measurement in the Langendorff-perfused guinea pig heart
- Involvement of voltage-dependent Ca'2+' channel .BETA.3 subunit in sympathetic regulation of heart rate and contractility
- Role of E-NTPDase1/CD39 in ATP-induced modulation of norepinephrine exocytosis in heart
- Analysis of the late asthmatic model animal using NC/Nga mice
- Development of alcohol-induced asthma model in mice
- Analysis of different allergic reactions between two strains of mice
- High sensitivity of mice by measurement of respiratory function using whole body plethysmography
- Pharmacological studies on a rat model of chronic obstructive pulmonary disease induced by cigarette smoke exposure
- Effects of codeine on capsaicin- or citric acid-induced coughs and sneezes in guinea-pigs
- Effect of serum thymic factor (FTS) on antigen induced early and late phase nasal blockage in a guinea pig model of allergic rhinitis
- Respiratory and lung changes by tobacco smoke exposure in mice
- Induction of apoptosis by the Asafoetida and its related compounds in Jurkat and HL-60 cells
- Nitric oxide decreases membrane water permeability and induces aquaporin-5 S-nitrosylation in lung epithelial cells
- Pharmacological studies on the respiratory tract (Rept. 276): Interleukin-13 induces upregulation of RhoA protein in the bronchial smooth muscle in human and mice
- Pharmacological studies on the respiratory tract (Rept. 278): mRNA expression of NO synthase subtypes and augmentation of responsiveness to NO of nasal mucosa from nasal hyperresponsive rats
- Pharmacological studies on the respiratory tract (Rept. 279): Effect of lovastatin on augmented bronchial smooth muscle contraction in antigen-induced airway hyperresponsive rats
- Pharmacological studies on the respiratory tract (Rept. 280): Upregulation of MMP12 in lungs of rats with allergic bronchial asthma
- Involvement of P2X receptor subtypes in ATP-induced enhancement of the cough reflex sensitivity
- Protease-activated receptor 4-mediated increase in [Ca'2+']i in cultured mouse lung epithelial cells
- PAR2 signaling for production of IL-8 and prostaglandin E2 in human lung epithelial cells
- Effects of short-term progesterone exposure on respiratory activity
- NMDA mechanisms in depolarization of augmenting expiratory neurons during the expulsive phase of fictive cough in decerebrate cats
- Effects of .OMEGA.1 subtype-selective hypnotic zolpidem on the activities in both hypoglossal and phrenic nerves in rabbits
- Effects of olmesartan, an AT1 receptor antagonist, on hypobaric hypoxia-induced activation of ERK1/2 and expression of IL-6 in mouse lung
- Hydrogen sulfide, a novel endogenous gasomessenger, causes relaxation in mouse bronchial smooth muscle
- Effects of phenol ethers, safrole and anethole, on the tracheal smooth muscle
- Effect of H-1152 on the force produced by muscarinic receptor stimulation in rat bronchial smooth muscle
- Y-27632 augments the inhibitory effect of propofol in rat ronchial smooth muscle contraction
- PPAR.GAMMA. partial agonist activity and PPAR.ALPHA. inverse agonist activity of capsaicin
- Pathophysiological role of mast cells in scleroderma
- Pharmacological studies on the pressure ulcer (Rept. 3): Changes in level of .ALPHA.1-acid glycoprotein and number of mast cells in pressure ulser of rats
- The development of new atopic dermatitis models in BALB/c mice
- TPA-induced mast cell degranulation and the activation of pro-MMP-9 in mice
- Crosstalk signaling between calcium-dependent and -independent pathways in thromboxane A2-induced fibroblast contraction in wound healing process
- Antinocieptive effect of spinally administered kyotorphin: Involvement of .DELTA.-opioid receptors
- Antinociceptive effects of YM-230888, a potent, selective and orally-active antagonist of type 1 metabotropic glutamate receptors, at chronic pain models
- Molecular cloning, functional characterization of the porcine TRPV1 (pTRPV1) and pharmacological comparison with endogenous pTRPV1
- Centrally-acting antitussives depress drug-induced hyperactivity in mice
- High frequency of ophthalmic malformation and altered thermal pain response in mice lacking apelin
- Triple histamine receptors genes knockout mice and their phenotypes
- Key roles of complement activation and prostaglandin I2 for exudate formation in zymosan-induced mouse pleurisy
- Osmotic homeostasis mediated through urine outflow regulation by TRPV4 in the central nervous system
- .BETA.-Neurexin selectively regulates synaptic vesicle accumulation in developing axon terminals of zebrafish olfactory sensory neurons in vivo
- Effects of geraniol, a herbal monoterpene alcohol, on cellular calcium mobilization
- Involvement of ubiquitin-proteasome system in the cytotoxic effect of mutant protein kinase C gamma found in spinocerebellar ataxia type 14
- A possible role of hydrogen sulfide as a synaptic modulator in rat hip-pocampal neurons
- Functions of histone deacetylase SIRT1 in undifferentiated neural cells
- Estrogen enhances BDNF release from DG granule cells via classical ER-independent and PKA-dependent mechanisms
- Hepatocyte growth factor attenuates the decreases in the number of synapses after NMDA-induced excitotoxicity
- Effects of lipopolysaccharide on aquaporin expression in retinal Mueller cells
- The localization and the dynamics of F-actin capping protein in hippocampal neurons
- Modulation of NR1/NR2A-subtype NMDA receptor channels by SAP102
- DISC1 interacts with RNA-binding proteins in messenger ribonucleoprotein complex
- Drebrin-A closslinks F-actin, and inhibits the activity of myosin-V in vitro
- Tributyltin-induced Ca'2+' mobilization via activation of L-type voltage-dependent Ca'2+' channels in PC 12 cells
- Cadherin activity is required for activity-induced spine remodeling
- Three kinds of modulations of P/Q-type (Cav2.1) Ca'2+' channel activity by metabotropic glutamate receptor subtype 1a (mGluR1a)
- Effect of HRD1 involved in endo-plasmic reticulum-associated degradation (ERAD) on degradation of amyloid precursor protein (APP) and suppression of beta amyloid (A.BETA.) production
- Stimulation of GABAc receptors activated PKA through AKAP220
- Phosphatidylinositol (PI) protects amyloid .BETA. protein-induced neuronal death in a transgenic mouse expressing V337M human tau
- .BETA. subunits of voltage-gated sodium channels are novel substrates of .BETA.-site amyloid precursor protein-cleaving enzyme (BACE1) and .GAMMA.-secretase
- Enhancement of glutamate cytotoxicity by A.BETA.25-35 via suppression of the PI3K/Akt pathway in differentiated PC-12 cells
- Mechanisms of endoplasmic reticulum stress-induced leptin resistant
- The NMDA receptor function is impaired by the disruption of actin binding protein drebrin A
- V-1, a novel regulatory protein of TH gene expression, serves as a cytoplasmic anchoring protein of CapZ to promote F-actin formation, resulting in the enhancement of maitotoxin-induced catecholamine secretion in PC12D cells
- Developmental expression of zebrafish glutamate receptor .DELTA.2
- Molecular cloning and expression patterns of zebrafish receptor protein tyrosine phosphatase .SIGMA.
- Molecular cloning and expression patterns of zebrafish SynCAM1 genes
- Molecular cloning and expression pattern of zebrafish TM4SF2 gene
- Impaired cerebellar climbing fiber innervation in the nervous system-specific FAK deficient mice
- Generation of TARP .GAMMA.-2 (stargazin) conditional knockout mouse
- Isolation of suppressor mutants from unc-51 and unc-14 mutants that have axon guidance defects
- Enhanced expression of RNase-L by glutamate in cultured cortical neurons
- Zebrafish GABAA receptor .ALPHA.6 subunit is expressed in three neural circuits showing characteristic cerebellum-like wiring
- Proteomic analysis of glutamate receptor .DELTA.2 mutant mice
- Distribution and protein levels of WASP family in brains of Alzheimer's disease
- Establishment of GluR .DELTA. 2-tTA mouse line expressing tetracycline-controlled transactivator (tTA) selectively in cerebellar Purkinje cells
- Effect of berberine on Alzheimer's amyloid A .BETA. peptide production in neuroglioma H4 cells
- Association of TRPM2 channel with a novel EF-hand protein, EFHC1
- Centrally mediated analgesic effects of the anticonvulsant zonisamide in inflammatory pain and painful diabetic neuropathy
- Pharmacological characterization of 7-hydroxymitragynine, an alkaloid from Thai medicinal plant Mitragyna speciosa, antinociception, tolerance and cross-tolerance to morphine in mice: Involvement of .MU.-opioid receptors
- Spinal cord injury enhances the 5-HT-induced inhibition of spinal monosynaptic reflex in rats
- Study of neuropathic pain mechanisms II: Phosphorylated ERK in various segments of spinal cord following somatic and visceral pain
- The relation of .KAPPA.-receptors to hyperalgesia in SART (repeated cold)-stressed mice
- Effects of fluvoxamine on allodynia- and anxiety-like behavior induced by sciatic nerve ligation in mice
- Contribution of capsaicin-sensitive fibers on spinal ventral root after-discharges evoked by nociceptive mechanical stimuli
- Opioid effects of indole alkaloids related to Thai narcotic herb Mitragyna speciosa
- Gastrointestinal transit inhibition by oxycodone and fentanyl is mediated by .MU.-opioid receptor
- Characterization of micturition-related single neuron activities and their distribution in periaqueductal gray matter (PAG) in anesthetized rats
- Modification by clorgyline, a monoamine oxidase-A inhibitor, of morphine-induced hyperlocomotion and antinociception in mice
- The intracerebroventricular administration of D-serine potentiates antinociceptive effect
- The intracerebroventricular administration of D-serine potentiates the antinociceptive effect of morphine on tail flick response in rats
- Analgesic action of intrathecal nicotine on the tibial nerve transection (TNT)-induced mechanical allodynia in rats
- Antinociceptive effect of McN-A-343 on noxious stimulation and mechanical allodynia
- Differential effects of N-peptidyl-O-acyl hydroxylamines on dynorphin-induced antinociception in the mouse capsaicin test
- Cellular distribution of peripheral benzodiazepine receptor in the brain injury produced by ethanol injection
- Relationships between individual differences in morphine analgesia and P-glycoprotein activity of brain capillary endothelial cells in mice
- Formalin-induced nociception alters expression of cation chloride cotransporters in the rat spinal cord
- Influences of hypothermia on anesthetic effect and pharmacodynamics of propofol in cardiopulmonary bypass patients and rats
- (-)-Pentazocine thermal and mechanical antinociception are eliminated and chemical antinociception reduced in .MU.-opioid receptor knockout mice
- .ALPHA.2-adrenergic and 5-HT2A receptors mediate the antiallodynic effect of fluoxetine in neuropathic pain mice
- Blockade of glycine transporter type 1 reduces neuropathic and inflammatory pain
- Antinociceptive effect of prostaglandins in neuropathic pain model rats
- Involvement of brain PKC in nitrous oxide (N2O)-induced antinociception in mice
- Gabapentin supraspinally accelerates spinal noradrenaline turnover in a murine neuropathic pain model
- Gabapentin reduces GABAergic synaptic transmission in locus coeruleus neurons following partial nerve injury in mice
- Mechanism of pain-related behavior evoked by intrathecal morphine-3-gluclonide
- BMP signaling induces transdifferentiation of microglia into functional neurons
- Induction of DNA double-strand breaks and repair proteins before neural progenitor cell differentiation
- Hyperexcitability arrests newly-born cells in the dentate hilus ex vivo
- Neuronal differentiation of ES cells grown on Matrigel, reconstituted basement membranes
- Effect of N-acetyl-L-cysteine on proliferation in neural progenitor cells of the hippocampus
- Possible enhancement of neurogenesis after neuronal injury in olfactory system of mice
- Effects of .ALPHA.1-adrenergic receptor agonist on the proliferation of embryonic neural progenitor cells in vitro
- Cerebral salt wasting after subarachnoid hemorrhage is directly proportional to the bleeding amount
- Mechanism of delayed neuronal death produced in SHRSP by transient forebrain ischemia
- SUN N8075, a novel neuroprotective agent, shows long-term neuroprotection in rats subjected to transient focal cerebral Ischemia
- SUN N8075, a neuroprotective agent, state-dependently blocks Na'+' and T-type Ca'2+' channels and Inhibits glutamate release during cerebral Ischemia in rats
- FK506 reduces hemorrhagic transformation produced by delayed t-PA treatment in the thrombotic focal cerebral ischemia in spontaneously hypertensive rats
- Protective effect of serofendic acid on ischemic damage induced by a middle cerebral artery occlusion in rats
- Prostaglandin E2 produced by microsomal prostaglandin E synthase-1 exacerbates ischemic brain injury
- Moduration of cell cycle reduces neuronal cell death observed after ischemia-reperfusion in the rat retina
- A behavioral method, circling behavior, for evaluating brain injury induced by hypoxia-ischemia in neonatal rats
- Analysis of genes whose expression is altered by brain temperature in rat forebrain ischemia model
- Screening for control genes in mouse hippocampus after transient forebrain ischemia using high-density oligonucleotide array
- Differential neuroprotective effects of delta9-tetrahydrocannabinol but not cannabidiol results in tolerance to the neuroprotective effects in mice subjected to middle cerebral artery occlusion
- Prostaglandin E2 aggravates ischemic injury via EP4 in a murine model of cerebral thrombosis
- Involvement of Na'+'/Ca'2+' exchanger-1 (NCX1) in reperfusion injury induced by middle cerebral artery occlusion in mice
- Exogenous microglia protect against focal brain ischemia in rats
- Increased endoplasmic reticulum stress in the hippocampus of apolipoprotein E-deficient mice after cerebral ischemia and reperfusion
- The effect of HGF on tight junction proteins after cerebral ischemia
- Effects of neuroprotective agents on focal ischemia-induced neuronal damage in mice
- Investigation for the effects of neuroprotective agents, cyclopentenone prostaglandin analogues in rat stroke model
- The actions of azelnidipine, a novel dihydropyridine-derivative Ca antagonist, on voltage-dependent Ba'2+' currents in guinea-pig vascular smooth muscle
- A smooth muscle relaxant extracted from Physarum polycephalum (2nd report)
- Arachidonic acid enhances the hydrolysis step of ATPase by way of conformation change of the smooth muscle myosin
- Effect of PDGF and sodium butyrate on growth, morphology, and properties of cultured vascular smooth muscle cell line AC01
- Physiological roles for .BETA.-adrenoceptor (.BETA.-AdR) and its subtypes in rat thoracic aorta
- Histamine-induced relaxation mediated by H2-receptor and its distribution in rat blood vessels
- Blebbistatin blocks PDGF-induced migration of vascular smooth muscle cell through inhibiting the ATPase activity of smooth muscle myosin II
- Effects of the extract from Nandina domestica Thunberg on the tracheal smooth muscle of the guinea pig
- Pharmacological studies on the respiratory tract (Rept. 277): Protein kinase C subtypes involved in acetylcholine-induced contraction of rat bronchial smooth muscle
- TRPV1-independent relaxant effects of capsaicin and resiniferatoxin on isolated ileum in guinea-pig
- Effect of LTD4 on decreasing acetylcholine induced contractions by H2O2 and AA861, an inhibitor of 5-lipoxygenase in guinea-pig ileum
- In vitro development of intestine-like tissue demonstrating rhythmic motility from embryonic mouse intestinal cells: Development of interstitial cells of Cajal
- Effects of distigmine on the motilities of guinea-pig detrusor and urethral smooth muscles
- Herb derived substances, lignans are protective against cell death via p38 MAPK by reactive oxygen species in C2C12 myoblast cells
- Immunochemical studies on migration and acin remodeling in vascular smooth muscle cells following sphingosylphosphorylcholine stimulation
- Characterization of recombinant full-length smooth-muscle myosin light chain kinase
- Intracellular release and the subsequent extracellular release of ATP evoked by bradykinin from cultured smooth muscle cells
- Expression and Characterization of Heavy mero-myosin (HMM) of Physarum polycepharum
- The distributions of miRNA from the differentiated and de-differentiated vasucular smooth muscle cells
- Effect of manipulating serum phosphorus with sevelamer hydrochloride, a phosphate binder, on circulating parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23) levels in rats with chronic renal insufficiency
- Inhibition by tranilast of nifedipine-induced proliferation of cultured human gingival fibroblasts
- Involvement of calcineurin in osteoclastogenesis mediated by RANKL
- Effect of cytokine on ESE-3 expression in human oral epithelial cells
- PPAR .DELTA.-regulated c-fos promoter activity contributes to RANKL-induced osteoclastogenesis
- Berberine inhibits RANKL-, TNF.ALPHA.-, LPS- and PGN-induced mature osteoclasts survival
- TNF receptor Type1 has a pivotal role for local bone resorption induced by LPS in vivo
- Molecular cloning and expression of a truncated isoform of CLCA in rat submandibular gland
- nrf2 expressed by bone and cartilage
- Effects of alendronate alone and in combination with MK-4 on bone mineral density in phenytoin induced osteopenia in growing rats
- Improvement of the bone quality by trehalose in ovariectomized mice
- Phenolic componds enriched in the traditional antidiarrheic inhibit ovariectomy-induced bone loss
- Effect of Boiogito on a rat osteoarthritis model
- The synergistic effect of atorvastatin and raloxifene on bone density in ovariectomized rats
- Contribution of TGF-.ALPHA. to EGF receptor transactivation leading to proliferative response of rabbit gingival fibroblasts to angiotensin II and endothelin-1
- Erk-1/2 signaling regulates cleft formation in submandibular gland branching morphogenesis
- Glutamatergic signaling machineries expressed by mesenchymal stem cells line C3H10T1/2 cells
- The effectiveness on gene expression profiling of cytokines in collagen-induced arthritis (CIA) model rats
- Differences in coupling interval-dependent effects of sotalol on infarcted and noninfarcted areas of dog hearts after myocardial infarction
- Protective effect of rosiglitazone on rat myocardial reperfusion injury: Difference according to administering method
- KP-102 (GHRP-2) attenuates ischemia/reperfusion injury in the isolated rat hearts
- Effect of aging on ischemia-reperfusion injury in siolated rat hearts
- Protective effects of EGCg against postischemic myocardial dysfunction in guinea pig hearts
- Effects of short-term Ginkgo biloba extract feeding on hypotensive action of nicardipine in rat
- Examination of a method for making the repetitive evaluation of respiratory functions in a cardiovascular study using monkeys
- Evaluation of drug-induced orthostatic Hypotension (OH) in a conscious dog using telemetry system
- Influence of .OMEGA.-3 fatty acid on platelet-leukocyte complex formation in patients undergoing cardiac surgery
- Accumulated endogenous NOS inhibitors and accelerated arginase activity in impaired NO production in pulmonary hypertensive rats
- Bloodborne factor from rat with common bile duct ligation causes blunted hypoxic pulmonary vasoconstriction via NO and KCa channel
- Angiontensin II leads to impairment of SERCA-dependent relaxation and enhancement of nitrotyrosine in diabetic rat aorta
- Inhibitory effect of lomerizine on TRP channel-mediated calcium influx
- The effects of antithrombotic drugs on coagulation time and thrombus formation in an AV-shunt model
- Anti-atherosclerotic effect of Pioglitazone in metabolic syndrome model rat
- Hyperfibrinogenemia in spontaneously hypertensive and hyperlipidemic rats is independent from IL6 pathway
- Pioglitazone improves matrix metalloproteinase-9 activity in plasma in a metabolic syndrome model rat
- Effect of angiotensin AT1 receptor antagonist on the vascular expression of eNOS and phosphorylated eNOS in spontaneously hypertensive rats
- Expression of Rho kinase and MYPT1 is increased in carotid arteries from spontaneously hypertensive rats (SHR)
- Rho kinase-mediated phosphorylation at Thr-850 of MYPT1 in the resting state of carotid arteries from spontaneously hypertensive rats (SHR)
- Pharmacokinetic characterization of celiprolol-grapefruit juice interaction in rats
- Higher sympathetic activity in standing related to lower parasympathetic activity in supine position
- Plasmin-induced endothelium-dependent relaxation in coronary artery
- Mechanisms underlying the impaired EDHF-type relaxations in the mesenteric artery from type 2 diabetic rats
- Rho-kinase phosphorylates eNOS at Thr495 in vascular endothelial cells, and inactivates it
- Proteinase-activated receptor (PAR)-1 activation potentiates myofilament Ca'2+' sensitivity and induces pulmonary artery contraction
- Inhibitory action of 1-stearoyl lysophosphatidic acid on the migration of smooth muscle cells from porcine coronary artery
- Alterations in contractile response in caudal arterial smooth muscle in type II diabetic Goto-Kakizaki (GK) rats
- Impaired function in rat mesenteric arteries treated with endotoxin
- Membrane depolarization-induced contraction of rat caudal arterial smooth muscle involves activation of Ca'2+' sensitization: Rho-associated kinase-mediated phosphorylation of MYPT1
- Characterization of histamine- and serotonin-induced contractions in porcine cerebral and ciliary arteries
- Analysis of relaxant responses to norepinephrine in swine coronary arteries
- Alteration of contractile responses in the first and the second branches of mouse mesenteric artery
- A crucial role of Rac1 in membrane targeting of thrombin receptor in vascular smooth muscle cells
- The importance of Fyn in sphingo-sylphosphorylcholine (SPC)-induced contraction of vascular smooth muscle cells
- Oxidative stress enhanced a trypsin-induced endothelium-dependent relaxation in the rat aorta
- Angiotensin II enhances contractile responses via PI3-kinase p110.DELTA. pathway in aortas from diabetic rats with systemic hyper-insulinemia
- Proteomic profiling of cultured human coronary smooth muscle cells stimulated with angiotensin II
- Inhibitory effect of azelnidipine, a long-acting dihydropyridine Ca'2+' channel antagonist, on in vivo and in vitro experimental coronary spasms
- Influence of experimental SAH on effects of levcromakalin, nifedipine and nicotinic acetylcholine receptor blockers in nicotine-induced endothelium-dependent contraction (EDC) in rat basilar artery
- Participation of arginine vasopressin and leukotrienes in development of cerebral vasospasm after subarachnoid hemorrhage
- Roles of chymase in the stenosis after polytetrafluoroethylene grafts implantation
- Neuronal nitric oxide inhibits the neurogenic norepinephrine release in rat mesenteric resistance arteries
- Effect of the phosphodiesterase IV inhibitor rolipram on allergic footpad swelling using various adjuvants
- Role for cyclic ADP-ribose in calcium signaling in human neutrophils
- Expression of choline acetyltransferase mRNA in mouse antigen-presenting cells
- Chloride channel 4 (CIC-4) expression on lipopolysaccaride (LPS) stimulation in human B leukemic cells
- Physiological role and activation mechanism of the oxidative stress-susceptible TRPM2 Ca'2+' channel in immunocytes
- Hydrogen peroxide at a low concentration protects RAW264 cells against hydrogen peroxide-induced apoptosis through the induction of catalase
- The mechanisms of catalase induction by nitric oxide and hydrogen peroxide
- MAPK-mediated down regulation of asparagine synthetase during TPA-induced differentiation of HL-60 cells
- Effects of chronic nicotine administration on antibody production in C57BL/6 mice
- Inhibitory effect of purine derivatives on histamine release in RBL-2H3 cells
- Participation of cytokine- and apoptosis-related genes to acute allograft rejection in rats
- Non-clinical safety and human subject protection during clinical trials of monoclonal antibodies and their analogs for human use
- Possible differential roles of COX-1 and COX-2 products on the later phase of an acute inflammatory model
- Expression of mRNA encoding prostaglandin D2 synthase and DP receptor in mononuclear leukocytes of C57BL/6J mice
- Regulation of inflammatory cells by protein transduction of intracellular molecules with inhibitory function
- Effect of phosoholipase C (PLC) and cytosolic phospholipaseA2 (cPLA2) in fMLP-induced eosinophil functions
- Enhancement of EAAC1-mediated glutamate transport activity by Arl6ip-1
- Age-related impairement of the responsiveness of AQP5 to muscarinic agonists in rat parotid glands
- Thioredoxin interacts with Ras and inhibits GTPase activity through reduction of cysteine oxidation
- Possible relation between endoplasmic reticulum (ER) stress and caspase dependent pathways in glycochenodeoxycholic acid (GCDCA) induced apoptosis in human hepatoma cell line, HepG2
- Novel surrogate ligands that stimulate human P2Y12 receptors were identified by in silico and in vitro fusion methods
- Amlodipine, a dihydropyridine Ca'2+' channel blocker, induces G1 cell-cycle arrest in human epidermoid carcinoma A431 cells
- N-acetyl-cysteine enhances growth in chronic myeloid leukemia oncoprotein, BCR-ABL-transformed cells
- Role of interaction between Filamin and CRMP2 in Semaphorin 3A signaling
- Isolation and identification of signal molecules interacting directly with endothelin receptors
- Isolation and preliminary characterization of a dorsal lectin from the redfin velvetfish, Hypodytes rubripinnis
- Selective allosteric ligand activation of the retinoid X receptor heterodimers of NGFI-B and Nurr1
- c-YES specific inhibition by ebselen: A target discovery through the comprehensive analysis of human protein-drug interactions
- Effects of reactive sulfur species on the conversion of xanthine dehydrogenase (XD) to oxidase (XO) in the liver
- Effects of endocrine disruptors on the formation of prostaglandin and arachidonoyl-CoA formed from arachidonic acid in kidney medulla microsomes
- Effects of cholesterol biosynthesis-associated compounds on HRD1 expression and protection against hypoxia-induced cell death
- Statistical estimation of drug-receptor model parameters
- Proteomic expression profiling of liver toxicity in rat in 28-day repeated dose study
- Molecular characterization of chicken neuromedin B and its receptor
- Duplicated .ALPHA.7 nicotinic receptor gene product directly interacts with .ALPHA.7 receptor in human SH-SY5Y neuroblastoma cells
- Renal specific chloride channel CIC-5 is regulated by the transcription factor HNF1.ALPHA.
- Effects of a nonsense-mediated mRNA decay inhibitor on a splice variant with PTCs
- Inducible expression of dominant-negative CREB by Tet-On system suppressed lens differentiation during zebrafish development
- Technology for high-throughput RNAi library construction
- Comprehensive analysis of bHLH-PAS proteins by using the wheat germ extract expression system and SPR biosensors
- Identification and characterization of novel ubiquitin ligases involved in ER-associated degradation (ERAD)
- A possibility as an anticancer agent using hTERT-regulating gene on human chromosome 10
- Caffeine perturbs mRNA expression of AP-1 transcription factors and iodide transporters in BeWo cell cultures and rat placenta
- Systematic multi genotyping for drug metabolizing enzyme and drug transporter in human in liver
1
- Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: Preface
- Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: Physiological Role of Angiotensin II-Induced Oxidative Stress in Renal Medulla
- Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: Renoprotective Effects of Aldosterone Blockade
- Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: The Role of Nuclear Factor .KAPPA.B Activation in the Development of Renal Fibrosis
- Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: Renoprotective Effect of Rho-Kinase Inhibitor in Hypertensive Glomerulosclerosis
- Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: Role of Rho-Kinase in the Development of Renal Injury
- Analysis of Vasoreactivity of Isolated Human Radial Artery
- Anti-arthritic Effects of Ephedra sinica S
TAPF Herb-Acupuncture: Inhibition of Lipopolysaccharide-Induced Inflammation and Adjuvant-Induced Polyarthritis - Regulation of Lipoprotein Lipase Expression by Effect of Hawthorn Flavonoids on Peroxisome Proliferator Response Element Pathway
- Effect of Clarithromycin on the Pharmacokinetics of Cabergoline in Healthy Controls and in Patients With Parkinson's Disease
- Relationship of Intracellular Calcium and Oxygen Radicals to Cisplatin-Related Renal Cell Injury
- Effect of Cyclosporin A on Immediate Early Gene in Rat Global Ischemia and Its Neuroprotection
- Lysophosphatidic Acid (LPA) Induces Plasma Exudation and Histamine Release in Mice via LPA Receptors
- Acute Hypokalemia May Not Be an Effective Way to Sensitize the In Situ Canine Heart for Sparfloxacin-Induced Long QT Syndrome
2
- The Sigma1 Protein as a Target for the Non-genomic Effects of Neuro(active)steroids: Molecular, Physiological, and Behavioral Aspects
- c-Jun N-terminal Kinase Contributes to Norepinephrine-Induced Contraction Through Phosphorylation of Caldesmon in Rat Aortic Smooth Muscle
- A Novel Effect of Bifemelane, a Nootropic Drug, on Intracellular Ca'2+' Levels in Rat Cerebral Astrocytes
- Inhibitory Mechanism of Monensin on High K'+'-Induced Contraction in Guniea-Pig Urinary Bladder
- Protective Effect of Zinc Against Ischemic Neuronal Injury in a Middle Cerebral Artery Occlusion Model
- Benidipine, a Calcium Channel Blocker, Regulates Proliferation and Phenotype of Vascular Smooth Muscle Cells
- Generalization of NMDA-Receptor Antagonists to the Discriminative Stimulus Effects of .KAPPA.-Opioid Receptor Agonists U-50,488H, but Not TRK-820 in Rats
- Induction of Heme Oxygenase-1 Inhibits Monocyte Chemoattractant Protein-1 mRNA Expression in U937 Cells
3
- Intrahepatic Flow Disturbance: Possibility of a Hidden Cause of Drug Toxicity
- Use of Ginseng in Medicine With Emphasis on Neurodegenerative Disorders
- Current Topics in Pharmacological Research on Bone Metabolism: Inhibitory Effects of Bisphosphonates on the Differentiation and Activity of Osteoclasts
- Current Topics in Pharmacological Research on Bone Metabolism: Osteoclast Differentiation Regulated by Glycosphingolipids
- Current Topics in Pharmacological Research on Bone Metabolism: Molecular Basis of Ectopic Bone Formation Induced by Mechanical Stress
- Current Topics in Pharmacological Research on Bone Metabolism: Promyelotic Leukemia Zinc Finger (PLZF) and Tumor Necrosis Factor-.ALPHA.-Stimulated Gene 6 (TSG-6) Identified by Gene Expression Analysis Play Roles in the Pathogenesis of Ossification of the Posterior Longitudinal Ligament
- Current Topics in Pharmacological Research on Bone Metabolism: Regulation of Bone Mass by the Function of Endogenous Modulators of Bone Morphogenetic Protein in Adult Stage
- Characterization of Muscarinic Receptor-Mediated Cationic Currents in Longitudinal Smooth Muscle Cells of Mouse Small Intestine
- The Effects of Ethosuximide on Amino Acids in Genetic Absence Epilepsy Rat Model
- Hypersensitivity to Hydroxyl Radicals in Rat Basilar Artery After Subarachnoid Hemorrhage
- Voltage-Dependent Ca'2+'-Channel Block by Openers of Intermediate and Small Conductance Ca'2+'-Activated K'+' Channels in Urinary Bladder Smooth Muscle Cells
4
- Pharmacological, Pharmacokinetic, and Clinical Properties of Benidipine Hydrochloride, a Novel, Long-Acting Calcium Channel Blocker
- Physiological Significance of Thromboxane A2 Receptor Dimerization
- Functional Arterial Baroreflex Attenuates the Effects of Antihypertensive Drugs in Conscious Rats
- Effects of Intra-arterial Urokinase on a Non-human Primate Thromboembolic Stroke Model
- Characteristics of Scratching Behavior Induced by Some Chemical Mediators in Hairless Mice
- Dimethylsphingosine Regulates Intracellular pH and Ca'2+' in Human Monocytes
- Role of Substance P on Histamine H3 Antagonist-Induced Scratching Behavior in Mice
- Effects of Dofetilide and EGIS-7229, an Antiarrhythmic Agent Possessing Class III, IV, and IB Activities, on Myocardial Refractoriness in Hyperkalemia, Hypokalemia, and During .BETA.-Adrenergic Activation in the Rabbit Papillary Muscle In Vitro
- Peripheral Antinociception by Carbamazepine in an Inflammatory Mechanical Hyperalgesia Model in the Rat: a New Target for Carbamazepine?
5
- Cardiac Myocytes Ca'2+' and Na'+' Regulation in Normal and Failing Hearts
- Cardiac Adrenoceptors: Physiological and Pathophysiological Relevance
- The Emergence of a General Theory of the Initiation and Strength of the Heartbeat
- A Missing Link Between a High Salt Intake and Blood Pressure Increase
- Tissue Angiotensin II Generating System by Angiotensin-Converting Enzyme and Chymase
- Biological, Physiological, and Pharmacological Aspects of Ghrelin
- Organic Anion Transporter Family: Current Knowledge
- Molecular Pathopharmacology of 5-HT2C Receptors and the RNA Editing in the Brain
- Molecular Mechanism of Neuronal Plasticity: Induction and Maintenance of Long-Term Potentiation in the Hippocampus
- How Do Acupuncture and Moxibustion Act? - Focusing on the Progress in Japanese Acupuncture Research -
- Brain Cytokines and Chemokines: Roles in Ischemic Injury and Pain
- Mechanisms of the Antinociceptive Action of Gabapentin
- A New Frontier in Epilepsy: Novel Antiepileptogenic Drugs
- Water Channels and Zymogen Granules in Salivary Glands
- Pharmacological Studies on Fullerene (C60), a Novel Carbon Allotrope, and Its Derivatives
- Calcium Ion as a Second Messenger With Special Reference to Excitation-Contraction Coupling
- Signal Transduction and Ca'2+' Signaling in Intact Myocardium
- Ca'2+'-Dependent Inositol 1,4,5-Trisphosphate and Nitric Oxide Signaling in Cerebellar Neurons
- Calcium Signals for Egg Activation in Mammals
Supplement 1
101
- The Role of Serotonin in Behaviour: from the Genesis of an Experimental Approach to Constitutive Activity
- Examining the Function of Serotonin in Brain: from Depression to Ecstasy
- 5-HT7 Receptors as a Pharmacological Target in Neuropsychiatric Disorders
- 5-HT7 and 5-ht5A Receptors: Their Emerging Roles in Brain Function and Available Pharmacological Tools
- Recent advances in the field of 5-HT7 receptor agents with 1-arylpiperazine structure
- The Role of Central 5-HT7 in the Control of Micturition and the Cardiovascular System
- Regulation of 5-HT1A Receptor Function in BDNF Deficient Mice
- Reciprocal Interaction of 5-HT and Neuronal Activity in Regulation of CRE-dependent Gene Expression
- SERTain Regulation of Serotonin Neurotransmission by BDNF
- Exploring Functional Interactions between SERT and BDNF in the Mediation of Emotional Behavior Using Mutant Mice
- Serotonergic drugs for the treatment of obesity
- Agonist Diversity in 5-HT2C Receptor-mediated Weight Control
- Promising Novel 5-HT6 Receptor Ligands to Treat Obesity
- Assessment of the Potential Efficacy and CNS side-effects of Novel Serotonergic Anti-obesity Agents in Phase 1 Clinical Studies
- Distinct Effects Mediated by Corticotropin-releasing Factor (CRF) Receptor Subtypes May Determine Opposing Coping Styles
- Microcircuitry of the Raphe and its Regulation by Stress
- Activity of presumed serotonin neurons: Are they all the same?
- Genetic Mechanisms directing Development of Serotonin-modulated Behaviors
- Cognitive Effects of Psilocybin, the Role of 5HT1 and 5HT2 Receptors in Cognition"
- Neural Substrates Underlying the Modulation of Decision-making and Error Processing by Psilocybin
- Effect of Estrogen on Serotonin-1A Receptor-mediated Disruption of Prepulse Inhibition
- Alterations of 5-HT1A and 5-HT2A Receptors and the 5-HT Transporter in Anorexia and Bulimia Nervosa: Results from PET Imaging Studies
- 5-HT1 receptors: Pharmacological Targets in the Cardiovascular System, from Migraine to Preeclampsia
- Receptor Mechanisms involved in the Cardiac Sympatho-inhibition Induced by ergotamine
- The Role of 5-HT1B/1D Receptors Mediating a Specific Inhibition on Capsaicin-induced Canine External Carotid Vasodilatation.
- Dual serotonergic regulation of the failing cardiac ventricle: Mechanisms and possible therapeutic consequences
- Mood Disorders and Serotonin-induced Calcium Mobilization
- Trait and State Marker, Serotonin Transporter Gene Expression
- Role of Serotonin in Prediction of Future Rewards-Toward Elucidation of Pathophysiology in Depression-
- Quantitative Imaging of Serotonin Transporter in Living Human Brain
- Multiple Serotonin Receptor Subtypes Contribute to the Effects of Serotonin in Rat Prefrontal Cortex
- Cell-type Specific Effects of Serotonin in Cortex
- Serotoninergic Modulation of Cortical Neuron Input Selectivity.
- Immunomodulatory Actions of Serotonin Enhancing Agents: Friend or Foe?
- Serotonin as a Modulator of Dendritic Cell Function: a Link to Asthmatic Airway Inflammation?
- Intracellular Serotonin Signaling: The Modulatory Role of Monoaminylation on G Protein Activity
- MATRICS: New Opportunities for Serotonin in Psychiatric Disorders
- The Galanin 3 Receptor and Serotonin Modulation
- Potential of 5-HT6 Antagonists for the Treatment of Cognitive Disorders
- ACP-103 a 5-HT2A Receptor Inverse Agonist, as an Adjunctive Therapy in Schizophrenia
- The Role of the C-terminus of the Human 5-HT3A Receptor Subunit
- Dynamic Behaviour of the 5-HT3 Receptor
- Serotonergic mechanisms and 5HT3 receptors in abnormal intestinal function
- Serotonergic Integration of Behavioral Input to the Mammalian Circadian Timing System
- Differential Effects of Arousal Procedures on Circadian Clock Resetting across Species: Role of Serotonin
- Role of 5-HT1a/ 5-HT7 receptors in central and peripheral circadian clocks
- Drug-induced phase shifts of SCN neuronal firing in vitro: Roles for 5HT1A, 5-HT5A and 5HT7 receptors
- Medicinal Chemistry approaches toward novel, selective 5-HT6 receptor ligands
- Increased Expression of 5HT6 Receptors in Rat Striatum Impairs Instrumental Learning
- Selective 5-HT6 Compounds as a Novel Approach to the Treatment of Alzheimer's Disease
- Selective 5-ht6 Ligands as a Novel Approach to the Treatment of Obesity and Related Metabolic Disorders
- Non-classical Modes of Signaling by 5HT2C Receptors
- PDZ-domain Proteins and 5-HT Signaling
- RSK2 Exerts a Tonic Brake on 5-HT2A Signaling
- Calmodulin Interacts with and Modulates 5-HT1a and 5-HT2a Receptors
- Antidepressant and Anti-anxiety Effects of the Neurotrophins BDNF and IGF-1 and their Dependence on Serotonergic Transmission
- Contribution of Hippocampal Neurogenesis to the Behavioral Effects of Antidepressants
- The Role of Serotonin in Behavioral and Cellular Changes in CREB Deficient Mice
- The Potential Role of 5-HT6 Receptor Stimulation in Antidepressant Drug Action and Neuronal Plasticity
- Serotonin (5-HT) Increases and Prolongs p38 MAPK Activation in Osteoclasts
- Functional expression of 5-HT2A receptors in mouse osteoblasts.-Activation of ERK pathway by 5-HT2A receptors on osteoblastic cell proliferation-
- Serotonergic system regulates cellular differentiation in mouse osteoblasts.
- Anti-inflammatory drugs inhibit a delayed increase of serotonin formation in rat ileum after cisplatin administration
- A 5-HT4 agonist mosapride enhances rectorectal and rectoanal reflexes in guinea pigs.
- Regulation of Gastrointestinal Pacemaker Activity Via 5-HT3 Induced Ca'2+' Influx
- Human Arterial Constrictor Serotonin Receptors
- Enhanced inhibitory effect of 5-hydroxytryptamine on interleukin-1.BETA.-induced nitric oxide production by vascular smooth muscle cells derived from stroke-prone spontaneously hypertensive rats.
- CNS5/Jab1 reduces L-type Ca'2+' current in cardiac myocyte.
- Induction of Functional Serotonin 5-HT2A and 5-HT4 Receptors in the Acute Failing Cardiac Ventricle
- Serotonin Responsiveness through 5-HT2A and 5-HT4 Receptors is differentially Regulated in Hypertrophic and Failing Rat Cardiac Ventricle
- Treatment with a 5-HT4 Serotonin Receptor Antagonist Improves Function of the Failing Heart
- The 5-HT4 receptor-a foetal gene reactivated in heart failure?
- 5-Ht1b/1d and 5-Ht7 Receptor-Mediated Vasodilatation in the Middle Meningeal Artery of Anesthetized Rats: Effect of Lesion of the Central 5-Ht System
- Potential Vascular Alpha1-adrenoceptor Blocking Properties of an Array of 5-HT Receptor Ligands in the Rat
- Pharmacological Identification of the Mechanisms Involved in the Inhibition Induced by Ergotamine on the Cardioaccelerator Sympathetic Outflow in Pithed Rat
- Modulation of maternal care by editing of the serotonin 2C receptor 5-HT2CR)
- Alterations in head-twitch response to a 5-HT2A agonist in thiamine deficient mice
- Involvement of the 5-HT2 receptor subtypes in anti-immobility effects of noradrenaline and dopamine reuptake inhibitors in mice
- 5-Hydroxytriptamine 2 receptors in dorsomedial medulla oblongata contribute to the onset of initial hyperventilatory response to acute hypoxia in mice
- Chronic treatment with SSRIs desensitizes both 5-HT2A and 5-HT2C receptor function
- Serotonin increases glial cell line-derived neurotrophic factor (GDNF) expression in C6 glioma cells: Implication in Src family-dependent fibroblast growth factor receptor (FGFR) transactivation
- Effect of nicotine cessation on wet-dog shakes mediated by 5-HT2A receptors in rats
- Effects of monoamine-related drugs on the model of 5-HT2A receptor hyperfunction induced by treatment of ACTH in rats.
- Ejaculatory response induced by a 5-HT receptor agonist m-CPP in rats; differential roles of 5-HT2 receptor subtypes
- Altered RNA Editing of the 2C-Subtype of Serotonin Receptor (5-HT2CR) Results in Paradoxical Alterations in Feeding Behavior and Growth in Mutant Mice
- Role of serotonin 5-HT2C receptor in aggressive behavior induced by social isolation in mice
- A possible Role for 5-HT2C Receptors in Postsynaptic Feedback Regulation of 5 HT Neurones
- RNA Editing and Short Variant of 5-HT2C Receptor in Neuronal Differentiated Cells
- Serotonergic interventions ameliorated the symptomatic abnormalities in an animal model for attention-deficit/hyperactivity disorder
- Dosing time dependent variance of anti-immobility effect of fluvoxamine in forced swimming test
- Nonuniform distribution of serotonin transporter in the hippocampus and neocortex of the mouse
- Buried Treasure? Is there a Function for the Esterase Activity of the Synaptic Protein that binds Paroxetine?
- Acute and Chronic Fluoxetine Treatments Differentially Modulate Cytoskeletal Microtubule Dynamics and Serotonin Metabolism in Rat Hippocampus.
- Changes in Tissue 5-HT and 5-HIAA Contents in Eleven Discrete Brain Regions after Four Days Treatment with Duloxetine, Venlafaxine, Milnacipran or Sertraline in Rats
- Altered Response to Selective Serotonin Reuptake Inhibitors in the Hippocampus of Adult BDNF Heterozygous .+-. Mice
- The effects of antidepressants on the phenotype specific neuronal differentiation in vitro
- Modulation of .ALPHA.2-adrenoceptors in the milinacipran-induced synaptic plasticity in the rat hippocampo-medial prefrontal cortex
- Influence of selective serotonin reuptake inhibitors (SSRIs) upon hamster circadian activity rhythms
- Measuring and manipulating tph2 transcript levels in the mouse brain
- Basolateral nucleus of the amygdala is the target brain site of the anxiolytic effect of citalopram, a selective serotonin reuptake inhibitor.
- Involvement of 5-HT2C receptors in conditioned fear-related responses
- The Mechanism of Action of Prozac (Fluoxetine) in C.elegans - Novel Pathways
- 5-HT1A Receptors in the Amygdala are Ivolved in the Regulation of Anxiety-like Behavior
- Involvement of 5-HT1A receptors in the lomomotor stimulant and sensitizing effects of methamphetamine in mice
- Effect of a selective 5-HT1A agonist tandospirone on abnormal involuntary movements in rat L-DOPA-induced dyskinesia model
- Learning and Memory Abilities of Mice Overexpressing the 5-ht1a Receptor in Dentate Gyrus and Cortex
- Effective Adjunctive Use of Tandospirone with Perospirone for Enhancing Verbal Memory and Quality of Life in Schizophrenia: Role of Serotonin1A Agonism in Cognitive Enhancement
- Amphetamine-induced attenuation of hyperactivity and prepulse inhibition deficits in mice lacking PACAP
- Effects of a Galanin-3 Receptor Antagonist on Neurite Outgrowth
- Electrophysiological and neurochemical characterization of milnacipran on the rat serotonergic and noradrenergic systems
- Effect of the stimulation of serotonin1A (5-HT1A) receptor on neurogenesis and neuroprotection
- The Carotid Vasodilator Responses to Capsaicin are Inhibited by Donitriptan, but not by Sumatriptan, via Stimulation of 5-HT1B Receptors in a Canine Model of Migraine
- Critical Role of the C-terminal Amino Acids of the Human 5-hYdroxytryptamine3A Receptor Subunit
- The Serotonin-Receptor Antagonist Ondansetron is able to Inhibit Proliferation of Acute Lymphoblastic Leukemia Cells, Putatively by Activation of a Pathway involving the inducible No-synthase (iNOS)
- 5-Hydroxytryptamine (5-HT) concentration in cisplatin-induced emesis
- The Human Hippocampus Displays the Potential to Express both Homomeric and Heteromeric 5-HT3 Receptors
- Paroxetine-induced emesis in suncus murinus
- Regulation of the Human 5-ht5A Receptor Cell Surface Expression by N-glycosylation
- PRX-07034, a Potent and Selective 5-HT6 Receptor Antagonist, Reduces Food Intake and Body Weight in Rats
- Influence of Median or Dorsal Raphe 5, 7-DHT Lesions on 5-ht6 Receptor Antagonist Activity in a Novel Object Discrimination Paradigm
- 5-HT6 Receptor Over-expression in the Striatum Decreases Autoshaped Learning
- An Investigation of 5-HT7 mRNA Expression in Hamster Brain during Aging
- Activation of Adenylyl Cyclase in HEK293 Cells by Endogenous Gs-coupled Receptors is attenuated by 5-HT7 Receptor Expression
- Rat Brain ex vivo Binding Method Allows for the Determination of CNS Penetrance and Potency of 5-HT7 Receptor Ligands
- Involvement of Spinal 5-Ht7, but not 5-Ht1a Receptors in the Systemic Morphine Antinociception
- Noradrenergic transmission within the central amygdaloid nucleus contributes to the negative affective component of visceral pain in rats
- Role of noradrenergic transmission within the bed nucleus of the stria terminals in visceral pain-related aversion in rats
- Role of noradrenergic transmission within the bed nucleus of the stria terminals in somatic pain-related aversion in rats
- 5-Hydroxytryptamine Potentiates Transient Receptor Potential V1 Functions in Rat Primary Sensory Neurons
- Serotonergic profile of a Parkinson disease model rat infected with Japanese encephalitis virus
- 5-HT Transporter Affinities for Pethidine and Norpethidine, and Their Role in Serotonin Syndrome
- Effects of co-administration of antidepressants and monoamine oxidase inhibitors on 5-HT-related behavior in rats.
- The Involvement of Serotonin in the Dorsal Hippocampus in Nmda Receptor Antagonist-Induced Locomotor Hyperactivity is Specific to Phencyclidine and not Mk-801
- Effects of serotonin on membrane potential of postnatal developing neurons of prefrontal cortex among Wistar rat substrains
- Involvement of Serotonergic System in Early Postnatal Stress-induced Emotional Susceptibility at Postadolescent Period of Rats
- A Possible model of depression: recoveries from reduction in 5-HT release in the amygdala and disturbance of circadian rhythm of activity induced by the chronic dexamethasone infusion in rats
- Change of AP-1 in brain of dexamethasone infusion rats
- Effects of diabetes on stress-induced 5-HT secretion in the medial prefrontal cortex and freezing behavior in mice
- Evidence for a Link between Brain Angiotensin, Serotonin and Behavior
- Behavioral stress and activated serotonergic neurotransmission induce XBP-1 splicing in the rat brain
- Effects of Fluoxetine and Imipramine on Behavioral, Neuroendocrine and Neurochemical Effects of Chronic Mild Stress in Mice
- Changes in emotional behavior of mice in the hole-board test after olfactory bulbectomy
- The Role of the CREB Pathway in Controlling 5-HT Neuron Activity and Emotional Behavior
- Effects of supplemental administration of 5-HT2 receptor antagonist on glucose metabolism in KK-A'y' mice treated with pioglitazone.
- Combination of sub-threshold doses of Aricept and PRX-07034, a novel 5-HT6 receptor antagonist, enhances Novel Object Discrimination (NOD) memory
1
- Recent Advances in Molecular Pharmacology of the Histamine Systems: Regulation of Histamine H1 Receptor Signaling by Changing Its Expression Level
- Recent Advances in Molecular Pharmacology of the Histamine Systems: Roles of C-terminal Tails of Histamine Receptors
- Recent Advances in Molecular Pharmacology of the Histamine Systems: Physiology and Pharmacology of Histamine H3 Receptor: Roles in Feeding Regulation and Therapeutic Potential for Metabolic Disorders
- Recent Advances in Molecular Pharmacology of the Histamine Systems: Immune Regulatory Roles of Histamine Produced by Leukocytes
- Recent Advances in Molecular Pharmacology of the Histamine Systems: Organic Cation Transporters as a Histamine Transporter and Histamine Metabolism
- Effects of Erythropoietin on Cardiac Remodeling After Myocardial Infarction
- Cyclic ADP-Ribose Requires FK506-Binding Protein to Regulate Intracellular Ca'2+' Dynamics and Catecholamine Release in Acetylcholine-Stimulated Bovine Adrenal Chromaffin Cells
- Screening for Control Genes in Mouse Hippocampus After Transient Forebrain Ischemia Using High-Density Oligonucleotide Array
- Development and Evaluation of a Direct Sandwich Enzyme-Linked Immunosorbent Assay for the Quantification of Guinea-Pig Immunoglobulin E
- A Critical Role of TRPM2 in Neuronal Cell Death by Hydrogen Peroxide
- Glucocorticoid Is Involved in Food-Entrainable Rhythm of .MU.-Opioid Receptor Expression in Mouse Brainstem and Analgesic Effect of Morphine
- The Mechanism of Endothelium-Independent Relaxation Induced by the Wine Polyphenol Resveratrol in Human Internal Mammary Artery
- Platelet Separation From Whole Blood in an Aqueous Two-Phase System With Water-Soluble Polymers
- Inhibitory Effect of Zacopride on Cisplatin-Induced Delayed Emesis in Ferrets
- Differential Expression of Platelet Glycoprotein Ia/IIa in Taiwan Chinese Corresponds to Glycoprotein Ia Gene Polymorphisms
2
- Mechanisms for the Anti-nociceptive Actions of the Descending Noradrenergic and Serotonergic Systems in the Spinal Cord
- Effects of Eppikahangeto, a Kampo Formula, and Ephedrae herba Against Citric Acid-Induced Laryngeal Cough in Guinea Pigs
- Nitric Oxide/cGMP Signaling Pathway Protects RAW264 Cells Against Nitric Oxide-Induced Apoptosis by Inhibiting the Activation of p38 Mitogen-Activated Protein Kinase
- Epidermal Growth Factor Induces Vasoconstriction Through the Phosphatidylinositol 3-Kinase-Mediated Mitogen-Activated Protein Kinase Pathway in Hypertensive Rats
- Heterotrimeric G Protein G.ALPHA.13-Induced Induction of Cytokine mRNAs Through Two Distinct Pathways in Cardiac Fibroblasts
- Doxorubicin Induces Apoptosis by Activation of Caspase-3 in Cultured Cardiomyocytes In Vitro and Rat Cardiac Ventricles In Vivo
- Long-Term Treatment With Imidapril but Not With Nifedipine Enhances Plasma NOx Concentration in Patients With Essential Hypertension
- The Antioxidative Effects of Astragalus Saponin I Protect Against Development of Early Diabetic Nephropathy
- Extracellular-Added ADP-Ribose Increases Intracellular Free Ca'2+' Concentration Through Ca'2+' Release From Stores, but Not Through TRPM2-Mediated Ca'2+' Entry, in Rat .BETA.-Cell Line RIN-5F
- New Therapeutic Application of Erythropoietin Against Ischemic Heart Diseases
3
- Control of Proliferation and Differentiation of Neural Precursor Cells: Focusing on the Developing Cerebellum
- Systemic Inflammatory Response Syndrome (SIRS): Molecular Pathophysiology and Gene Therapy
- Effects of Galantamine and Donepezil on Active and Passive Avoidance Tests in Rats With Induced Hypoxia
- Glycoprotein Isolated From Ulmus davidiana N
AKAI Protects Against Carbon Tetrachloride-Induced Liver Injury in the Mouse - Acetylcholine Inhibits the Hypoxia-Induced Reduction of Connexin43 Protein in Rat Cardiomyocytes
- Inhibition by Selenium Compounds of Catecholamine Secretion Due to Inhibition of Ca'2+' Influx in Cultured Bovine Adrenal Chromaffin Cells
- Augmentation of Oridonin-Induced Apoptosis Observed With Reduced Autophagy
- The Role of Nitric Oxide in the Electrical Field Stimulation-Induced Contractions of Sphincter of Oddi and Gallbladder Strips in Guinea Pigs
- Analysis of Cardioprotective Effects Using Purified Salvia miltiorrhiza Extract on Isolated Rat Hearts
- Administration of Xenobiotics With Anti-estrogenic Effects Results in mRNA Induction of Adult Male-Specific Cytochrome P450 Isozymes in the Livers of Adult Female Rats
- Anti-inflammatory Effect of Spironolactone on Human Peripheral Blood Mononuclear Cells
4
- Functional Role of Spliced Cytoplasmic Tails in P2X2-Receptor-Mediated Cellular Signaling
- MicroRNA: Biogenetic and Functional Mechanisms and Involvements in Cell Differentiation and Cancer
- Proteomic Modification by Nitric Oxide
- Disturbance of Response to Acute Thermal Pain in Naturally Occurring Cholecystokinin-A Receptor Gene Knockout Otsuka Long-Evans Tokushima Fatty (OLETF) Rats
- Effects of Subchronic Treatment With Selegiline on
L -DOPA-Induced Increase in Extracellular Dopamine Level in Rat Striatum - First Phase of Glucose-Stimulated Insulin Secretion From MIN 6 Cells Does Not Always Require Extracellular Calcium Influx
- Blockade by NIP-142, an Antiarrhythmic Agent, of Carbachol-Induced Atrial Action Potential Shortening and GIRK1/4 Channel
- The Novel Hypoglycemic Agent YM440 Improves Hepatic Insulin Resistance in Obese Zucker Fatty Rats
- Effects of Antiarrhythmic Drugs on Apoptotic Pathways in H9c2 Cardiac Cells
- Potentiation of Ethanol in Spatial Memory Deficits Induced by Some Benzodiazepines
- Vascular Reactivity to Various Vasoconstrictor Agents and Endothelium-Dependent Relaxations of Rat Thoracic Aorta in the Long-Term Period of Pinealectomy
- Protein Kinase C .BETA. Inhibitor LY333531 Attenuates Intercellular Adhesion Molecule-1 and Monocyte Chemotactic Protein-1 Expression in the Kidney in Diabetic Rats
- The Effects of HMG-CoA Reductase Inhibitor on Vascular Progenitor Cells
- A Late Cutaneous Response in Actively Sensitized Rats: a New Method for Evaluating the Efficacy of Antiallergic Drugs
- Quantitative Fluorescence Measurement of Cardiac Na'+'/Ca'2+' Exchanger Inhibition by Kinetic Analysis in Stably Transfected HEK293 Cells
Supplement 1
102
- Direct Interaction Between Nerves and Mast Cells Mediated by the SgIGSF/SynCAM Adhesion Molecule
- Topics on the Na'+'/Ca'2+' Exchanger: Pharmacological Characterization of Na'+'/Ca'2+' Exchanger Inhibitors
- Topics on the Na'+'/Ca'2+' Exchanger: Involvement of Na'+'/Ca'2+' Exchange System in Cardiac Triggered Activity
- Topics on the Na'+'/Ca'2+' Exchanger: Responses of Na'+'/Ca'2+' Exchanger to Interferon-.GAMMA. and Nitric Oxide in Cultured Microglia
- Topics on the Na'+'/Ca'2+' Exchanger: Involvement of Na'+'/Ca'2+' Exchanger in the Vasodilator-Induced Vasorelaxation
- Topics on the Na'+'/Ca'2+' Exchanger: Role of Vascular NCX1 in Salt-Dependent Hypertension
- Aldose Reductase Inhibitors Improve Myocardial Reperfusion Injury in Mice by a Dual Mechanism
- NMDA Receptor-Antagonistic Properties of Hyperforin, a Constituent of St. John's Wort
- Identification of Amino Acid Residues Important for Sarpogrelate Binding to the Human 5-Hydroxytryptamine2A Serotonin Receptor
- Inhibition of Protein Tyrosine Kinases Attenuated A.BETA.-Fiber-Evoked Synaptic Transmission in Spinal Dorsal Horn of Rats With Sciatic Nerve Transection
- Skin Tests of a Novel Nicotine Patch, PHK-301p, in Healthy Male Volunteers: Phase I, Placebo-Controlled Study
- Inhibition of Arachidonic Acid Release by Cytosolic Phospholipase A2 Is Involved in the Antiapoptotic Effect of FK506 and Cyclosporin A on Astrocytes Exposed to Simulated Ischemia In Vitro
- Inhibition by SEA0400, a Selective Inhibitor of Na'+'/Ca'2+' Exchanger, of Na'+'-Dependent Ca'2+' Uptake and Catecholamine Release in Bovine Adrenal Chromaffin Cells
- Effects of Treatment for Diabetes Mellitus on Circulating Vascular Progenitor Cells
- Calcium and Reactive Oxygen Species Mediated Zn'2+'-Induced Apoptosis in PC12 Cells
- The Novel Src Kinase Inhibitor M475271 Inhibits VEGF-Induced Vascular Endothelial-Cadherin and .BETA.-Catenin Phosphorylation but Increases Their Association
- Effects of Bifemelane on the Calcium Level and ATP Release of the Human Origin Astrocyte Clonal Cell
- Combined Treatment of Ionizing Radiation With Genistein on Cervical Cancer HeLa Cells
- Effect of d-Pseudoephedrine on Cough Reflex and Its Mode of Action in Guinea Pigs
- .ALPHA.7 Nicotinic Acetylcholine Receptor Stimulation Inhibits Lipopolysaccharide-Induced Interleukin-18 and -12 Production in Monocytes
2
- Development of Genetically Engineered Mice Lacking All Three Nitric Oxide Synthases
- Signaling Pathways Involved in the Cardioprotective Effects of Cannabinoids
- Beta-Blockers Show Inverse Agonism to a Novel Constitutively Active Mutant of .BETA.1-Adrenoceptor
- Insufficient Expression of Cyclooxygenase-2 Protein Is Associated With Retarded Degradation of Aggregated Protein in Diabetic Glomeruli
- Protective Effect of Prostaglandin EP4-Receptor Agonist on Anti-glomerular Basement Membrane Antibody-Associated Nephritis
- Inverse Agonist Activity of Sarpogrelate, a Selective 5-HT2A-Receptor Antagonist, at the Constitutively Active Human 5-HT2A Receptor
- Lig-8, a Bioactive Lignophenol Derivative From Bamboo Lignin, Protects Against Neuronal Damage In Vitro and In Vivo
- Pharmacological Profiles of the Novel Analgesic M58996 in Rat Models of Persistent and Neuropathic Pain
- The Elucidation of the Mechanism of Weight Gain and Glucose Tolerance Abnormalities Induced by Chlorpromazine
- Increase in Expression of .ALPHA.1 and .ALPHA.2/.DELTA.1 Subunits of L-Type High Voltage-Gated Calcium Channels After Sustained Ethanol Exposure in Cerebral Cortical Neurons
- Acrylamide Analog as a Novel Nitric Oxide-Independent Soluble Guanylyl Cyclase Activator
- Azelnidipine Down-Regulates Renal Angiotensin-Converting Enzyme and Mineralocorticoid Receptor mRNA in Diabetic Hypertensive Rats
- Distribution of DJ-1, Parkinson's Disease-Related Protein PARK7, and Its Alteration in 6-Hydroxydopamine-Treated Hemiparkinsonian Rat Brain
- Beneficial Action of 2,4,4-Trimethyl-3-(15-hydroxypentadecyl)-2-cyclohexen-1-one, a Novel Long-Chain Fatty Alcohol, on Diabetic Hypoalgesia and Neuropathic Hyperalgesia
3
- Roles of Voltage-Dependent Sodium Channels in Neuronal Development, Pain, and Neurodegeneration
- An Experimental Model of Prolonged Esophagitis With Sphincter Failure in the Rat and the Therapeutic Potential of Gastric Pentadecapeptide BPC 157
- Inhibition of G Protein-Activated Inwardly Rectifying K'+' Channels by the Antidepressant Paroxetine
- Aldosterone Synthesis and Cytokine Production in Human Peripheral Blood Mononuclear Cells
- Hydrogen Peroxide-Induced Thymidine Incorporation Into Cultured Rat Astrocytes
- Fibroblast Growth Factor-2 Suppresses Oridonin-Induced L929 Apoptosis Through Extracellular Signal-Regulated Kinase-Dependent and Phosphatidylinositol 3-Kinase-Independent Pathway
- Hemostatic Action of OC-108, a Novel Agent for Hemorrhoids, Is Associated With Regional Blood Flow Arrest Induced by Acute Inflammation
- Pharmacokinetics and Anti-asthmatic Potential of Non-parenterally Administered Recombinant Human Interleukin-1 Receptor Antagonist in Animal Models
- Localized Expression of Histamine H1 Receptors in Syncytiotrophoblast Cells of Human Placenta
- Blebbistatin Inhibits Sphingosylphosphorylcholine-Induced Contraction of Collagen-Gel Fiber Populated by Vascular Smooth-Muscle Cells
- Modulation of ATP-Induced Inward Currents by Docosahexaenoic Acid and Other Fatty Acids in Rat Nodose Ganglion Neurons
- Type of Electrical Stimulation Influences Diaphragm Response to Adrenoceptor and Calcium Channel Modulators: the Role of Extracellular and Intracellular Calcium Events
- Morphological Change by Overexpression of D385A Dominant Negative Presenilin 1 in Human Neuroblastoma SH-SY5Y Cells
4
- Short-Term and Long-Term FK506 Treatment Alters the Vascular Reactivity of Renal and Mesenteric Vascular Beds
- Contribution of Extracellular Signal-Regulated Kinase to UTP-Induced Interleukin-6 Biosynthesis in HaCaT Keratinocytes
- Changes in Emotional Behavior of Mice in the Hole-Board Test After Olfactory Bulbectomy
- Silibinin Protects Against Isoproterenol-Induced Rat Cardiac Myocyte Injury Through Mitochondrial Pathway After Up-regulation of SIRT1
- Comparison of Four Rate-Correction Algorisms for the Ventricular Repolarization Period in Assessing Net Effects of IKr Blockers in Dogs
- Open-Label Study of the Safety and Pharmacokinetics of Solifenacin in Subjects With Hepatic Impairment
- Single-Dose Intravenous Simvastatin Treatment Attenuates Renal Injury in an Experimental Model of Ischemia-Reperfusion in the Rat
- Lack of Enhanced Effect of Antipsychotics Combined With Fluvoxamine on Acetylcholine Release in Rat Prefrontal Cortex
1
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