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List of Jounal Titles
A to Z index of Journal Title. Choose a letter.
Jpn J Pharmacol
97
- Regulatory mechanisms of synaptic transmission in the neural circuit
- Arterial aging in apparent health promotes arterial diseases
- Ghrelin: Discovery and physiological significance
- Cardiac adrenoceptors: Physiological and pathophysiological relevance
- Glia-neuron networks: A new target for neuropharmacology
- Cellular and molecular responses to cerebral hypoxia: Involvement of ER in neuronal death
- Pharmacology by a gleaner: Pharmacotherapeutics for the diseases due to tissue-generated angiotensin II
- Targets to correct contractility defects in heart failure
- Cellular mechanisms of immunomodulation by Ganoderma lucidum polysaccharides
- Multiple roles of mitochondrion during experimental endotoxemia
- Prediction of drug metabolism parameters in humans: in vitro and in silico insights
- Cardiac myocyte Ca'2+' and Na'+' regulation in normal and failing hearts
- Neuropharmacology of light, gas and gene
- Progress in chloride pharmacology in brain
- Regulations of the peripheral vascular tone by newly emerging Ca'2+' entry channels and endothelial cells
- New approach to cardiac tissue engineering
- Role of NCX, SR Ca'2+' ATPase and SR Ca'2+' leak in reducing SR Ca'2+' load in heart failure
- Molecular mechanism of vascular dysfunction in the insulin-resistant state
- Considerations for translational research for biologics
- Promotion of translational research-from the standpoint of pharmaceutical companies-
- Establishment of institutional GMP is mandatory for the development of translational research in cell therapy
- Translational research for evidence-based symptom management in palliative medicine
- Translational research in development of PET probes for early diagnosis of Alzheimer's disease
- Drug induced QT interval prolongation and safety pharmacology studies/ICH strategy
- Predisposing and aggravating factors in drug-induced long QT syndrome
- Pharmacokinetic/pharmacodynamic aspects of drug-induced long QT syndrome
- Cellular and ionic basis for acquired form of long QT syndrome
- Drug block of hERG channels: Reconciling pharmacophore and receptophore models
- In silico prediction of long QT intervals caused by drugs
- Role of drug transporters in the intestine and renal tubules
- Pharmacological and physiological roles of organic anion transporters in normal and cancer cells
- Role of drug transporters in the blood-brain barrier and blood-CSF barrier
- Na'+'-dependent antiporters: Molecular organization and therapeutic potential
- The normal homeostasis of phosphorus and its role in pathologic process
- Amino acid transporter inhibitors: Their therapeutic potential
- Effects of bisphosphonates on the differentiation and activity of osteoclasts
- Osteoclast differentiation regulated by glycosphingolipids
- Ectopic bone formation induced by mechanical stress
- Genes derived from ligament cells of OPLL patients during osteoblastic differentiation
- Regulatory mechanisms operating in adult bone formation
- Sodium channels and sudden death
- Protein modification of cardiac potassium channels and lethal arrhythmias
- Involvement of Ca'2+' regulatory proteins in lethal arrhythmias
- Pharmacological modification of spiral-type reentry
- Angiopoietin-1 promotes wound healing in diabetic mice and restores erectile function in atherosclerotic rat
- Non-hematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction
- Molecular mechanism of angiogenesis: Isolation and characterization of an endothelium-derived novel angiogenesis inhibitor
- Regulation of myosin phosphorylation in smooth muscle contraction
- Physiological and pathophysiological roles of local Ca'2+' transients in the regulation of cell excitability and contraction in smooth muscle cells
- Origin and proliferation of smooth muscle cells
- Role of ion channels in vascular smooth muscle cell apoptosis
- Intestinal inflammation evokes motility disorder by suppression of CPI-17 expression in smooth muscle cells: Involvement of interleukin-1.BETA.
- Hip/hop of chemogenomics
- Chemical biology of gene expression and cell differentiation
- Chemical-genomic network for integrating bioinformatics and chemoinformatics
- Chemical genomics of molecular imaging
- Chemogenomics and pharmacogenomics
- New challenges for acetylcholinesterase inhibitors as anti-Alzheimer's drugs
- A novel strategy for treatment of Alzheimer's disease through suppression of Abeta aggregation
- F-1, a natural compound, improves impairment of memory and inhibits beta-amyloid accumulation
- A role for glucagon-like peptide-1 in neurons and glias: The perspective as an useful tool in Alzheimer's disease studies
- Risk factors of Alzheimer's disease: Is preventive intervention possible?
- Properties and functional roles of T-type Ca'2+' channels in cardiac pacemaker cells
- Expression of T-type Ca'2+' channels in fetal and diseased hearts
- NRSE-NRSF regulates the transcription of fetal type cardiac ion channels
- Pharmacology of T-type Ca'2+' channel blockers
- Role of T-type Ca'2+' channels in renal microcirculation
- Promotion of banking system of human tissue in providing medical institution
- Human material for research and its remote: Authentication and privacy protection
- Establishment of public resource bank of human hepatocytes for research use
- Human muscle repository-from diagnosis to reserach
- New synaptic mechanisms revealed by synaptic transmission imaging
- Functions and plasticity of dendritic spines
- Spatio-temporal dynamics of intracellular dynamics
- Multiple function of PKC revealed by imaging techniques
- Functional analysis of Aurora A mitotic kinase by cell imaging
- Discovery research of oxacephem antibacterial agents
- From discovery of the first statin to the development of pravastatin
- Discovery of immunosuppressant Tacrolimus (Tac, FK506)
- Drug discovery in the fields of urology: Tamsulosin and solifenacin
- The research and development of donepezil, a therapeutic drug for Alzheimer's disease, and its future perspective
- Angiotensin II receptor blocker: Candesartan cilexetil
- SgIGSF: A new mast-cell adhesion molecule that mediates interaction with nerves
- A novel type of chronic allergic inflammation mediated by IgE/Fc.EPSILON.RI
- Mouse allergic dermatitis model and effects of tacrolimus on the dermatitis
- Diverse mechanisms of allergic itch
- Introduction: Current status, characteristics and potentials of ion channel drug discovery
- Pharmacological regulation of ATP-sensitive potassium channels
- TRP channels and novel calcium antagonists
- Fluorescent and electrophysiological high-throughput screening technologies for exploratory research on voltage-dependent ion channels
- Exploration of target genes and drugs: Fundamental technology for evaluation
- A new high-throughput electrophysiology platform using voltage clamp noise analysis
- Roles and significance of C-type natriuretic polypeptide (CNP) induced by PACAP
- The role of PACAP in the regulation of energy balance
- Effect of PACAP on the differentiation of neural stem cells into glial cells
- A link between up-regulation of pituitary adenylate cyclase-activating polypeptide and induction of neuropathic pain following nerve injury
- Role of PACAP in receptive relaxation of the mouse stomach
- PACAP knockout phenotypes: Functional changes in the CNS and platelets
- Stromal inflammatory signaling and tumor-associated angiogenesis
- Search for anti-angiogenic agents from the marine organisms
- Molecular mechanisms of retinal angiogenesis and treatment perspectives for diabetic retinopathy
- Therapeutic angiogenesis by bone marrow endothelial stem cells and cardiomyogenesis by cardiac-derived multipotent stem cells
- Use of genetically engineered mice for lymphatic vascular biology
- Molecular mechanisms of lymphangiogenesis in diseases and possible therapy for lymph node metastasis
- Pathological roles of microsomal prostaglandin E synthase-1
- Roles of leukotriene B4 receptor BLT1 in immunological reactions
- Roles of thromboxane A2 and prostacyclin in the development of atherosclerosis in apoE-deficient mice
- Roles of the prostanoids in the cardiovascular diseases
- Roles of lipid mediators in the chronic pain mechanism
- Kampo medicine - It's present role and future perspectives
- Globalization of Kampo medicine: Challenges and opportunities
- Economic evaluation for Kanpo medicine
- Aquaporins provide new insights into the molecular mechanisms to maintain water homeostasis, as a shared target of Oriental and Western medicines
- Evaluation of the effects by Kampo medicine by gene chip system
- Molecular mechanism for the regulation of Ca'2+' signaling and its failure in the heart
- Molecular basis of ryanodine receptor dysfunction in heart failure
- Pathophysiological analysis of aldosterone in heart failure
- Heart failure and cell cycle
- How to apply genomic science for new treatment of chronic heart failure: A new finding of the involvement of ER stress
- Pharmacogenomic approaches to individualization of warfarin therapy across different populations
- Pharmacogenomics in PPI-based H. pylori eradication therapy
- Personalized tacrolimus therapy for organ transplant patients focusing on detoxication factors
- What is needed to deliver the promise of pharmacogenomics? Discussing the challenges
- Appropriate pharmacogenomic approaches in clinical trials for regulatory submission
- Stress and the raphe nuclei
- Early postnatal stress and the serotonergic system
- Functional regulation of serotonin transporter, a key molecule for controlling stress and anxiety disorder
- Serotonergic mechanisms in acute and chronic stress
- Involvement of dysfunction of glutamatergic neuron in schizophrenia
- The involvement of polymorphism in 5-HT2A receptor gene in impulsive behavior
- The function of ATP in pain signalling: Involvement of microglia
- Role of platelet-activating factor in the transduction of pain signal in the spinal cord
- Leptin receptor and brain-immune function
- Implication of the cell-cell communication by the long-lasting activation of neuronal PKC in the development of morphine dependence
- Regulatory mechanisms of histamine H1 receptor signaling by changing the expression level of histamine H1 receptor
- Proteins that bind to the C-terminal tails of histamine receptors
- Identification of histamine receptors, and role of the histamine H3 receptor in obesity
- Differentiation and maturation of mast cells mediated by histamine
- Organic cation transporters as a histamine transporter and histamine metabolism
- Feeding regulation by NPY and recently discovered peptides
- Role of NPY/Y1 receptor axis in the hyperphagic response to T3-induced thyrotoxicosis
- Ghrelin-neuropeptide Y axis in the regulation of appetite and gastrointestinal motility
- Development of anorectic NPY antagonists
- Regulation of hypothalamic neuropeptide expression and feeding behavior in NPY-Y5 knockout (KO) mice
- A novel mechanism of mechanical stress-induced AT1 receptor activation
- Peripheral-type benzodiazepine receptor as a biological marker for stress disorders
- Functional analysis of muscarinic acetylcholine receptors using knockout mice
- Pharmacome analysis of muscarinic acetylcholine receptors by tissue segment binding method
- In vivo analysis of drug-receptor binding characteristics in drug discovery
- NMDA-receptor-mediated modulation of heterosynaptic plasticity
- The role of tyrosine phosphorylation of NMDA receptors in higher brain functions
- Enhanced susceptibility to seizure in hippocampal CA3 region-specific NMDA receptor knockout mice
- Critical roles of NMDA receptors in eyeblink classical conditioning
- Molecular mechanisms of cognitive deficits associated with N-methyl-D-aspartate receptor dysfunction
- Schizophrenia and glycine site agonists of the NMDA receptor
- Physiological role of angiotensin II induced oxidative stress in renal medulla
- Reno-protective effects of aldosterone blockade
- The role of NF-.KAPPA.B activation in the development of renal fibrosis
- Rho-kinase inhibitor in hypertensive glomerulosclerosis
- Rho kinase as a determinant of progressive renal injury
- Inhibitors of Na'+'/Ca'2+' exchanger
- The role of Na'+'/Ca'2+' exchanger system in cardiac triggered activity
- Modulation mechanism of Na'+'/Ca'2+' exchanger mRNA stability
- Modulatory mechanism of the cardiac Na'+'/Ca'2+' exchanger
- Responses of Na'+'/Ca'2+' exchanger to interferon-.GAMMA. and nitric oxide in cultured microglia
- Involvement of Na'+'/Ca'2+' exchanger (NCX) in vasodilator-induced vasorelaxation
- Role of vascular Na'+'/Ca'2+' exchanger-1 in salt-sensitive hypertension
- Role of endomorphin-1 on the process of learning and memory in the water-finding test in mice.
- Neuroprotective effects of intrastriatal grafting of encapsulated GDNF-producing cell on slowly progressive brain damage related to memory impairment following hypoxia-ischemic insult in neonatal rats
- Inhibitors of cyclooxygenases attenuate the action of NC-1900, a novel vasopressin fragment analog, on the step-through passive avoidance task in mice
- Effect of clozapine on cognitive dysfunction in chronic phencyslidine-treated mice
- Behavioral expressions to emotional stimuli in the rat experienced with traumatic events during periadolescence
- Sex differences in anxiety and aggression induced by long-term social isolation in mice
- Endocannabinoid system in the amygdala and nucleus accumbens: Role in relapse to methamphetamine seeking
- Studies on drug dependence (Rept. 402): Role of orexin neurons in the brain rewarding system
- Detection of protein-derived radicals by immunochemical technique
- AT1 receptor mediates isoproterenol-induced cardiac hypertrophy and oxidative stress
- Nox1, a catalytic subunit of NADPH oxidase mediates angiotensin II-induced hypertension
- The vasopressin V1a receptor is involved in the maintenance of resting blood pressure
- Flow-induced Ca'2+' transients regulate calpain-mediated changes in morphology in bovine aortic endothelial cells
- Mechanism for hypotonically induced contraction in canine basilar arteries
- Comparative effects of microplasmin and tissue-type plasminogen activator on cerebral hemorrhage in a middle cerebral artery occlusion model in mice
- Endothelial dysfunction of the pulmonary artery changes the neuro-cardio-endocrine axis after subarachnoid hemorrhage
- Investigation of blood components that cause acute or chronic vasopasm in rat model of experimental SAH
- Involvement of caldesmon phosphorylation mediated by Rho kinase-activated PKC.DELTA. in development of canine cerebral vasospasm after subarachnoid hemorrhage
- Characterization of transplanted skeletal myoblasts (SkM) to dilated cardiomyopathy (DCM) hamsters
- Effect of KMI-429, a novel .BETA.-secretase inhibitor, on A.BETA. production in the hippocampus of APP-transgenic Tg2576 and wild-type mice
- Facilitated effects of IL-1.BETA. on the biosynthesis of substance P in rat sensory neuron
- NT3 activates TrkC to enhance glial migration through Rac1/Cdc42/JNK
- Thermo-sensation in the mice lacking TRPV4 and in KJR mice, resistant to hot-plate hyperalgesia
- Effect of VDM11, a specific anandamide membrane transporter inhibitor, on capsaicin-induced coughs in mice
- Mechanisms underlying protection of oxidative-stress-induced damage of astrcoytes by extracellular ATP via P2Y1 receptors
- Thrombin-induced delayed neuronal death in cerebrocortical slice cultures
- GABAC receptor/PKA complex regulates neuronal apoptosis
- Neuroprotective effect of pramipexole against H2O2-induced PC12 cell death
- Neuroprotective effect of activity-dependent neurotrophic factor, ADNF, against toxicity by familial amyotrophic lateral sclerosis-linked mutant SOD1 in vitro and in vivo
- Skeletal muscle-specific expression of an .EPSILON.-sarcoglycan transgene prevents muscular dystrophy in a mouse model for limb-girdle muscular dystrophy 2D
- Origin and dynamics of smooth muscle cells in murine carotid allografts
- Expression and function of .ALPHA.1-adrenoceptor subtypes in rat anococcygeal muscles
- Effects of monensin on high K'+'-induced contraction in guinea pig urinary bladder
- Effects of papaverine on carbachol-induced contraction in bovine tracheal smooth muscle
- Receptor subtype responsible for the nicotine-induced vasodilatation via nitrergic nerve stimulation in canine cerebral artery
- Impairment of endothelium-dependent relaxation of rabbit cerebral artery after long-term in vivo administration of nitroglycerin
- Characteristics of vasorelaxation via the nitric oxide/cyclic guanosine monophosphate pathway in SHR/NDmcr-cp (cp/cp) rats, a model of metabolic syndrome
- Mechanisms underlying enhanced vasodilation following endothelium removal in rat mesenteric resistance vessels: involvement of the second messengers
- Histamine induces constriction and relaxation mediated by perivascular nerves in rat mesenteric resistance arteries without endothelium
- Identification of the isoforms of Ca'2+'/calmodulin-dependent protein kinase II and expression of BDNF mRNAs in the substantia nigra
- Alteration of substance P levels in various regions of mouse brain caused by cathepsin E-deficiency
- Protein kinase C.GAMMA.(.GAMMA.PKC) mutants found in spinocerebellar ataxia (SCA) preferably aggregate in the cytoplasm
- Capsazepine is a novel activator of the .DELTA. subunit of the human epithelial Na'+' channel
- Carboxy terminal region regulates the expression of human norepinephrine transporter splicing variants
- Regulation by NMDA signals of proliferative activity in neural progenitor cells
- Brain phospholipase C/diacylglycerol lipase is involved in the bombesin BB2 receptor-mediated activation of sympatho-adrenomedullary outflow in rats
- Iinhibition of leptin-induced signaling by 2-aminopurine
- Coadministration of sulpiride and fluvoxamine increases selectively in vivo dopamine release in rat prefrontal cortex
- Pharmacome study of intracellular muscarinic receptors in rat brain cortex
- Ca'2+' sensing transgenic mice: Postsynaptic signaling in smooth muscle
- Weakened interdomain interactions within RyR1 underlie the stimulated Ca'2+' release in malignant hyperthermia
- The functional analyses of ryanodine receptor type 2 (RyR2) in excitation-contraction coupling using urinary bladder smooth muscle of RyR2 heterozygous KO mouse
- Role of M2 and M3 receptor subtypes in the activation of muscarinic receptor-operated cationic channels in mouse intestinal smooth muscle cells
- Different glibenclamide-sensitivity of urethral ATP-sensitive K'+' currents using different patch-clamp recording methods
- Transcriptome analysis on an antidepressant drug, imipramine by zebrafish DNA microarray
- EPRIL-derived RNAi library: a new tool for comprehensive screening of functional genes
- "Piment" and "Macaroni": nervous system protein database
- NGF upregulates gicerin gene expression via cAMP response element
- PACAP-Reg signaling inhibits diabetes-induced islet hyperplasia
- Developmental change in the calcium channel subtypes involved in the excitatory synaptic transmission onto cholinergic neurons in the rat basal forebrain
- Long-term exposure of cerebrocortical neurons to a 1,5-benzodiazepine (clobazam) induces up-regulation of L-type high voltage-gated calcium channels (HVCCs)
- Mg'2+' modulates evoked inhibitory post-synaptic current in rat MNTB neurons
- Down-regulation of CICR gene expression by carbamazepine, via stimulation of CICR associated monoamine exocytosis
- Membrane-anchored CD14 is required for LPS-induced TLR4 endocytosis
- Cathepsin E is important for endosomal/lysosomal systems in macrophages against a bacterial infection
- Beta2-adrenergic receptor agonist induces IL-18 production without IL-12 production
- Effect of ciprofloxacin-induced PGE2 on IL-18-treated monocytes
- Roles of tyrosine kinases in p38MAPK activation, superoxide production and chemotaxis in FMLP-stimulated rat neutrophils
- Enhanced mechanism of insulin receptor signaling by chronic nicotine treatment
- Desensitization by G protein coupled receptor kinase 4 (GRK4) of the GABAB receptor-mediated signaling
- Sir2.ALPHA., an NAD-dependent histon deacetylase, is a nucleo-cytoplasmic shuttling protein
- Nuclear export and import mechanism of DGK.ALPHA.
- Development and characterization of membrane-permeable fluorescent cGMP-indicators
- The medial amygdala is involved in activation of angiotensin systems in the anterior hypothalamic area
- Generation of constitutively active calcineurin in mouse brain ischemia and its potential role in the neuronal death
- Comparative study of the mechanisms on endoplasmic reticulum stress-induced neuronal death in cultured rat hippocampal neurons and cerebellar granule neurons
- Age-related astrogliogenesis due to cortical .DELTA.-opioid receptor dysfunction
- Therapeutic application of neprilysin-mediated amyloid-.BETA. peptide-degrading system in Alzheimer's disease
- Molecular mechanisms of aggravated inflammation by dual infection of gram negative and positive bacteria via toll-like receptor 2 up-regulation in mice atrium
- Prostaglandin E1-initiated immune regulation in human mixed lymphocyte reaction
- Mechanisms of the development of anti-prolactin autoantibodies in patients with macroprolactinemia
- Complement-mediated cytotoxicity of rituximab to CD20 positive myeloma cell line MC/CAR
- Cremophor EL, a non-ionic surfactant, promotes Ca'2+'-dependent process of cell death in rat thymocytes
- Non-genomic regulation of cardiac ion currents by testosterone
- Assessment of the roles of predisposing factors in the onset of sparfloxacin-induced long QT syndrome
- The mechanisms of cardioprotection induced by a novel opener of large conductance Ca'2+'-activated K'+' channels
- Effect of propranolol on epinephrine-induced left ventricular dysfunction in primate using real-time three-dimensional echocardiography
- Angiotensin receptor blocker improves diastolic heart failure even on the end stage by the inhibition of oxidative stress and inflammation
- Gene expression of histamine H1 receptor and histidine decarboxylase in starved rats
- Differences of mRNA expression for histamine H3 receptor isoforms in rat hypothalamus according to gender, strain and starvation
- Effect of caffeine on neuropeptide gene expression in mouse brain
- Role of hypothalamic glutamate on radiation-induced emesis in rats
- Identification of agonists for a putative Caenorhabditis elegans G-protein-coupled receptor, C06H5.7
- Inhibitory mechanisms of salivary secretion by benzodiazepines-Characteristics of Ca'2+' influx induced by benzodiazepines in rat parotid acinar cells-
- Characterization of the rat Ca'2+'-activated Cl'-' channel OLGA expressed in ductal cells of rat salivary glands
- The role of PPAR.DELTA. in osteoclast differentiation
- The role of protein kinase C in osteoclast differentiation
- Analysis of PADI4 gene polymorphisms in rheumatoid arthritis
- Impairment of PI3-K/Akt pathway underlies attenuated endothelium-mediated relaxation and NO production in aorta of type 2 diabetic mouse model
- Up-regulation of angiotensin II type 2 receptor and endothelial nitric oxide synthase in aortas of mice with two-kidney, one-clip hypertension
- Effect of long-term administration of nitroglycerin on endothelium-dependent relaxation in rabbit intrapulmonary vein
- Roles for hydrogen sulfide, a novel endogenous gasomessenger, in modulation of the motility in isolated rat arterial tissues
- Detection of protein-derived radicals by immunochemical technique
- Phospho-dependent modulation of GABAA receptor by PRIP-1
- Phosphorylation of tau by CaM kinase II in neuronal soma
- Translocation of cPLA'2'.ALPHA. in cultured cerebellar Purkinje cells
- Concomitant translocation of Pur.ALPHA. with its binding proteins (PurBPs) from nuclei to cytoplasma during neuronal development
- Expression and molecular interaction of contactin associated protein (Caspr) 4 in central nervous system
- Selective down-regulation of insulin receptor substrate-2 by immunophilin ligands: involvement of calcineurin inhibition
- Identification of regulatory site of phopshorylation of neuronal nitric-oxide synthase at threonine1296
- Isoliquiritigenin enhances the hypoxic induction of HIF-1
- Functional proteomic screens reveal an essential extracellular role for hsp90.ALPHA. in cancer cell invasiveness
- Paradoxical reversal of Hsp90 inhibitor-induced BCR-ABL degradation by the BCR-ABL inhibitor
- Effects of memantine and donepezil on A.BETA.1-40-induced memory impairment in 3-lever operant task
- Effect of nilvadipine on the experimentally induced learning and memory disturbances in rats
- Behavioral pharmacology of plant-derived substances (14): Interaction between menthol and nicotine on ambulation in mice
- Circadian oscillation of Ca'2+'/calmodulin-dependent protein kinase II activity in the hamster suprachiasmatic nucleus
- The effect of music on calcium and dopamine-dependent blood pressure regulation in brain
- Hydrogen sulfide may play an important role in inhibition of insulin secretion
- Suppression by endogenous islet ghrelin of glucose-induced insulin release via inhibition of Ca'2+' signaling in rat pancreatic .BETA.-cells
- 1'st' phase of glucose-stimulated insulin secretion (GSIS) consists of KATP channel-dependent and -independent pathways
- Parathyroid cells express functional alpha 1C subunit of L-type calcium channel (CAGNA1C)
- Characterization of the expression and localization of stathmin in human endometrium
- Modified VEGF adenovirus vectors for angiogenesis gene therapy
- Chymase accelerates angiogenesis in hamster hindlimb ischemia model
- Estrogen receptor subtype involved in the coronary angiogenic pathway in female mouse hearts
- The novel transcript of NOX1, a catalytic subunit of NADPH oxidase is expressed under phenotypic modulation of vascular smooth muscle cells
- Thyroid hormone regulates vascular smooth muscle calcification
- Viability of neurons in ventral and dorsal horns of neonatal and adult mice spinal cord slices to ischemic insult
- Injured and non-injured primary sensory neurons produce monocyte chemoattractant protein-1 in neuropathic pain model rats
- Induction of cyclooxygenase-2 by bradykinin in rat dorsal root ganglion cells
- Potentiation of vanilloid receptor-mediated responses by 5-hydroxytryptamine in rat primary sensory neurons
- Facilitatory effect of adrenomedullin on redistribution of perivascular nerves in the rat mesenteric artery
- Relationship between MDR-1 polymorphisms and blood-brain barrier permeability of fexofenadine in human brain in vivo
- Effects of pentosan polysulfate (PPS) for Creutzfeldt-Jakob disease and a new drug designed by modification of PPS to sufficiently deliver into the brain
- Studies on drug dependence (Rept. 403): Implication of cyclin-dependent kinase 5 in the rewarding effect of morphine
- Studies on drug dependence (Rept. 405): Involvement of neuronal migrating regulator in the development of tolerance to morphine-induced antinociception
- De novo ceramide synthesis is involved in nephrotoxicity induced by radiographic contrast medium
- Effect of edaravone on renal tubulointerstitial injury caused by unilateral ureteral obstruction in rats
- Preventive effects of cyclohexenonic long-chain fatty alcohol on diabetic neuropathy in the rat bladder
- Effects of mineralocorticoid receptor (MR) blockade on albumin-induced monocyte chemoattractant protein-1 (MCP-1) expression in human proximal tubular cells (HPTCs)
- Pravastatin ameliorates suppressed bone formation in rats with adynamic bone disease induced by kidney disease
- The role of tyrosine kinase in cerebral vasospasm after subarachnoid hemorrhage
- Proteinase-activated receptor-1 antagonist prevented hyper-contractile response to thrombin in rabbit subarachnoid hemorrhage model
- Microplasmin reduces ischemic brain damage and improves neurological function in a rat stroke model monitored with magnetic resonance imaging monitoring
- Temperature elevation of coronary artery plaques is associated with the upregulation of the proinflammatory cytokine, IL-1.BETA.
- Role of cation channels in insulinotropic response to hyposmotic challenge in rat pancreatic .BETA.-cells
- The role of mitochondria in the regulation of glucose-induced insulin secretion by nitric oxide
- Endoplasmic reticulum stress-induced apoptosis in calmodulin-overexpressing pancreatic .BETA. cells
- Effect of progesterone on the expression of membrane-associated prostaglandin E2 synthase in ovarian granulosa cells
- Obesity in female histidine decarboxylase knockout mice
- The regulation of MMP/TIMP system on the sensitization induced by methamphetamine through the dopamine signaling in the rat
- Effect of antisense against organic cation transporter-3 on locomotor activity induced by methamphetamine
- Endocannabinoid system in the amygdala and nucleus accumbens: role in relapse to methamphetamine seeking
- Role of endomorphin-1 on the process of learning and memory in the water-finding test in mice
- Attentional function in male juvenile SHRSP, an animal model for AD/HD
- Comparison of monophasic action potential durations between at the sinus rhythm and during the fixed ventricular rate: Which rate-correcting formula for QT interval is the most reliable?
- Newly developed QT analysis system based on the ICH guideline
- Characterization of the conscious dogs as a model for assessing of the drug-induced QT prolongation
- Anti-atrial fibrillatory and electrophysiological effects of transdermal patch containing pilsicainide
- Conductivity of action potentials and Ca waves in Ca-overloaded ventricular muscles
- TRPM8 protein localization in trigeminal ganglion and taste papillae
- Pharmacological characterization of the cold sensitive TRP channel
- Effects of green tea extracts on blue light with Rose Bengal induced lipid peroxidation in porcine retinal homogenate
- Effect of herbal extracts and minerals on aquaporin-mediated water transport across plasma membrane
- Neuroprotective effects of intrastriatal grafting of encapsulated GDNF-producing cell on slowly progressive brain damage related to memory impairment following hypoxia-ischemic insult in neonatal rats
- Personalized treatment of Parkinson's disease-Effects of meal, grapefruit juice and domperidon on the pharmacokinetics of antiparkinsonian drugs-
- The relationship between nitric oxide, neuronal nitric oxide synthase, seizures, and cerebellar atrophy
- Dosing time-dependent disruptive effect of dexamethasone on biological rhythm in mice
- Studies on drug dependence (Rept. 401): The metabotropic glutamate receptor 5 (mGluR5) is critical for the development of tolerance to morphine-induced antinociception
- C-terminal dependent activation of vascular receptor-operated Ca'2+' entry channel TRPC6
- A putative mechanism for stimulatory effects of Mg'2+' on cardiac ryanodine receptor RyR2
- Long-term administration of amiodarone decreased the proarrhythmic substrates of the chronic atrioventricular block dogs
- Effects of KATP channel modulation on transmural dispersion of action potential duration in canine left ventricle
- Bepridil, an antiarrhythmic drug, activates mitochondrial ATP-sensitive K'+' channels and confers cardioprotection
- Distribution and functional roles of 5-HT2A and 5-HT7 receptors in porcine uterus
- Hormonal regulation of large conductance Ca'2+'-activated K'+' channel expression in rat vas deferens
- Possible contribution of TRPM7 to proliferative potential control of human leukemia K562 cells
- ACE inhibitor and AT1-R antagonist suppress tumor growth in a mouse model
- Role of nitric oxide in the synthesis of plasma fibrinogen in mice
- Effects of loperamide on tachykinin NK2/NK3 receptors-mediated serotonin release from guinea-pig colonic mucosa
- Experimental model of irritable bowel syndrome using conditioned fear response and the effectiveness of 5-HT3 receptor antagonist ramosetron in the model
- Nitric oxide mediated suppressive effect of .ALPHA.-lactalbumin on interleukin-6 release after intestinal ischemia/reperfusion in rat
- Intracellular signaling for prostaglandin E2 production caused by activation of the thrombin receptor, PAR-1, in the rat gastric mucosal epithelial cells
- Dexamethasone produces damage in the stomach but not small intestine under inhibition of cyclooxygenase (COX)-1
- Histaminergic involvement in the wake-promoting effect of modafinil: in comparison with methylphenidate
- Effects of histamine H1 receptor antagonists on the sleep-wakefulness cycle in sleep-disturbed rats
- Involvement of the histaminergic system in the spermine-induced pain-related behaviors in the mouse spinal cord
- The role of brain monoamine systems in the development of emotional resistance to stress stimuli mediated by 5-HT1A receptors in mice
- Behavioral expressions to emotional stimuli in the rat experienced with traumatic events during periadolescence
- Involvement of LOX-1 in endothelial dysfunction under hyperlipidemia
- Activation of proteinase-activated receptor-4 induces Ca'2+'-independent NO production in cultured bovine aortic endothelial cells
- Protein kinase C.DELTA. mediates induction of NOX1, a catalytic subunit of NADPH oxidase in vascular smooth muscle cells
- Pathophysiological role of chymase in the development of abdominal aortic aneurysm
- Elevation of chymase in monocrotaline-induced pulmonary hypertension in rat
- Establishment and analyses of a mouse asthma model induced by Dermatophagoides farinae (Der. f.)
- Pharmacological analyses of early (EAR) and late asthmatic response (LAR) in mice
- Evaluation of intranasal specific immunotherapy (SIT) for allergic rhinitis in guinea pigs
- A novel inflammation model using human lung tissue and its pharmacological application
- Prostanoid DP1 receptor agonist inhibits the pruritic activity in NC/Nga mice with atopic dermatitis
- A model for electrical pace-making activity by functional coupling between cloned ryanodine receptor and small-conductance Ca'2+'-activated K'+' channel
- Noninvasive and simple breath test using '13'C-acetic acid to evaluate gastric emptying in conscious rats
- Distinctive mechanism of acid-induced HCO3'-' secretion in rat stomach in comparison with duodenum
- Cholinergically stimulated gastric acid secretion is mediated by M3 and M5, but not M1, muscarinic acetylcholine receptors in mice
- Preclinical profile of AZD0865, a novel, selective, potassium-competitive acid blocker (P-Cab)
- Cadherin activity is required for activity-induced spine remodering
- Control of synaptic connection by glutamate receptor .DELTA.2 in the mature cerebellum
- Repeated exposure to addictive drug elicits synaptic adaptation in rat mesolimbic slice culture
- Effects of single and repeated treatments with milnacipran on synaptic plasticity in the hippocampo-medial prefrontal cortex pathways of anesthetized rat
- Secretion of a novel molecule that stimulates glycine-binding site to potentiate NMDA receptor-mediated responses by microglia
- The contribution of sympathetic nerve terminals to local cooling-induced reduction of skin blood flow in rats
- Effects of tea containing Hihatsu (Piper longum) extract on cold constitution
- Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice
- Contractile effects of perfluorooctanesulfonate (PFOS) in isolated rat arteries
- The Ca'2+' refilling to the sarcoplasmic reticulum is important for the agonist-induced tonic contraction in the porcine coronary artery
- CaM Kinase II activation is involved in Alzheimer's drug nefiracetam-induced long-term potentiation in the rat hippocampal slice
- Visualization of the range of nitric oxide signaling involved in synapse-specific plasticity in the mouse cerebellum
- Development of a novel fluorescent glutamate indicator for visualization of the synaptic transmission
- Development of novel PET imaging agent for amyloid plaques
- Visualization of extracellular ATP dynamics in the brain slice
- PPAR.GAMMA. antagonists induce anoikis in head and neck squamous cell carcinoma cells
- The effect of basic fibroblast growth factor on cell growth in nifedipine responder and non-responder
- Differentiation-inducing factor-1 induced cyclin D1 degradation through the phosphorylation on Thr'286' in squamous cell carcinoma
- Cyclic stretching and eicosapentaenoic acid synergistically inhibit adipocyte differentiation of 3T3-L1 cells
- Non steroidal anti-inflammatory drugs (NSAIDs) aggravate 1-methyl-4-phenylpyridinium (MPP'+')-induced cell toxicity via blockade of multidrug resistance proteins (MRPs) in PC12 cells
- Vasodilator prostaglandins increase fundus blood flow of tetrodotoxin-treated rats
- Effects of sarpogrelate, an inhibitor of 5-hydroxytryptamine (5-HT)2A receptor, and M-1, a major metabolite of sarpogrelate, on the 5-HT-induced vasoconstriction in isolated human internal thoracic artery and radial artery
- Mechanisms of human urotensin II-induced contraction in rat aortas
- Effects of a wine vinegar beverage on the renin-angiotensin system in vivo
- The mechanism of the antihypertensive effect of sesamin
- Regulation of renal urate transporter URAT1 transport function by PDZ domain protein PDZK1
- Identification and characterization of a novel mouse organic anion transporter (OAT10)
- HDAC inhibitor activates adult stem cell in kidney and prevents progression of glomerulonephritis
- Roles of chymase in the pathogenesis of arteriovenous fistula stenosis
- Sp1/Sp3 regulates expression of aquaporin-5 during the transdifferentiation of alveolar type II cells into type I cells
- Lung metastasis of cancer cells suppressed in p38.ALPHA. mitogen activated protein kinase knockout mice
- Pentostatin, an adenosine deaminase inhibitor, potentiates the anti-tumor effect of cordycepin on mouse B16-BL6 melanoma and Lewis lung carcinoma cells
- Identification of dominant-negative RAMP1 mutant able to inhibit CGRP1 receptor function
- Binding of mastoparan to gangliosides in lipid rafts affects intracellular signal transductions by changing the localization of signaling molecules
- The vasopressin V1a receptor is involved in the maintenance of resting blood pressure
- Effect of hyperglycemia on vascular responseveness in pithed rats
- Up-regulation of ATP-induced response through P2X4 receptors by interferon-.GAMMA. in endothelial cells
- Involvement of the central prostaglandin E2 in cardiovascular regulation in anesthetized rats
- The analysis of the pathophysiolosical significance of C-type natriuretic peptide (CNP) induced by pituitary adenylate cyclase activating peptide (PACAP) in rat astrocytes
- A canine urinary disturbance model in association with benign prostatic hyperplasia and combination treatment with propiverine plus tamsulosin
- Renal effects of a new member of adrenomedullin family, adrenomedullin2, in rats
- Effect of progressive renal failure in 5/6 nephrectomized rats
- Effect of postischemic treatment with FK409, an NO donor, on renal ischemia/ reperfusion injury
- BAD detects coincidence of G2/M phase and growth factor deprivation to regulate apoptosis
- Involvement of effector-caspase activation in the subcellular organelle to the apoptotic pathway
- Inhibition of irinotecan-induced apoptosis by increased p-glycoprotein in human hepatocellular carcinoma cells
- A selective M3 muscarinic receptor antagonist suppresses Colon 38 tumors in mice
- Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120
- Role of the prostaglandin I2-IP system in liver regeneration
- Protective action of prostacyclin/IP receptors against ischemia/reperfusion-induced gastric mucosal injury in mice
- Prostagtandin E2-EP1 signaling suppresses myoelectrical activity of gastric smooth muscle and inhibits gastric emptying
- A novel murine model of Graves' disease by in vivo electroporation expressing thyroid-stimulating hormone receptor
- Significance of M3 muscarinic acetylcholine receptor (mAChR) in Ca'2+' signaling to mAChR agonist in human leukemic T cell line CCRF-CEM (CEM) by reduction of response in small interfering RNA (siRNA)-treated cells
- Role of oxidative stress in aldosterone-induced cardiac injury
- PAR-1-mediated cell growth and PKC activation in rat cardiomyocytes
- AngiotensinII antagonizes insulin-mediated PI(3,4,5)P3 signaling in native cardiomyocytes via Ca'2+' dependent rather than PKC pathway
- Cardiac mitochondrial nitric oxide (NO)-cGMP pathway induces cytochorome c release via mitochondrial kinase pathway
- A novel cardiac-specific MAP kinase, TNNI3K, promotes cardiac differentiation and myogenesis in a pluripotent P19CL6 cell model
- 5-HT1A receptor is involved in amphetamine-induced paradoxical calming effect in PACAP-deficient mice
- The functional change in the 5-HT1A receptor induced by stress and the role of the 5-HT1A receptor in neuroprotection
- Upregulation of prostaglandin D synthase in oligodendrocytes by sleep deprivation stress
- The role of tissue plasminogen activator(tPA)in the rewarding effects of methamphetamine
- Hyper-responsibility of wide dynamic range(WDR)neurons in sural nerve ligation model of neuropathic pain and its suppression by gabapentin in mice
- Requirement of the transmembrane semaphorin Sema4C for myogenic differentiation
- Taurine transporter is transcriptionally regulated through MEF2 during skeletal muscle differentiation
- Cell-cell repulsion regulated by Ca'2+'-dependent translocation of PYK2 to focal adhesion
- Neurite extension induced by an intrinsic gicerin/CD146 in nerve cells
- Simulation analysis of intracellular signaling in nerve growth
- Organellar Ca'2+' dynamics underlying Ca'2+' oscillations
- Depolarization-induced Ca'2+' release (DICR) involves minor CICR in 1B5 myotubes expressing frog ryanodine receptors
- Microtubule depolymerization inhibits mast cell degranulation by decrease in Ca'2+' influx
- The mechanism of up-regulated CFTR trafficking by curcumin
- Expression of tight junction proteins (TJs) as adhesion structure in endothelial/epithelial cells and transendothelial electrical resistance (TEER)
- Large-conductance Ca'2+'-activated K'+' channel .BETA.1 subunit in cardiac mitochondria and cardioprotective effects of 17.BETA.-estradiol
- Combination therapy with angiotensin receptor blocker(ARB)and Ca channel blocker(CCB)exerts cardiovascular protection through inhibition of reactive oxygen species
- Endothelial apoptosis induced by cerivastatin may worsen myocardial contractile function during ischemia/reperfusion in dogs
- Effects of new quaternary ammonium compounds, TA375 and TA380, on stunned myocardium in dogs
- Apelin is a novel angiogenic factor
- Opioid analgesics-induced P-glycoprotein ATPase activation and analgesic effect
- Cannabidiol prevents cerebral infarction via the non-CB1 cannabinoid receptor mechanism
- Studies on drug dependence (Rept. 399): Involvement of astrocyte-released factors in the development of methamphetamine-induced rewarding effect in mice
- Studies on drug dependence (Rept.400): Molecular mechanisms underlying methylphenidate-induced psychostimulus effects
- Receptor dimerization of the .MU.-opioid and cannabinoid CB1 receptors
- High-throughput selection of effective short hairpin RNA(shRNA) constructs from RNAi library
- Overexpression of regucalcin suppresses proliferation in cloned rat hepatoma cells
- Sir2.ALPHA., an NAD-dependent histone deacetylase, is regulated by Notch1 signaling
- Regulation of Na'+' channel density by glycogen synthase kinase-3.BETA.: up-regulation by insulin-like growth factor-I, LiCl and valproic acid
- Knockdown of small conductance Ca'2+'-activated K'+' channel(SK2) suppressed the positive feedback regulation of intracellular Ca'2+' in t-BBEC 117
- A knock-in mouse model for dilated cardiomyopathy caused by .DELTA.K210 mutation in cardiac troponin T
- Drastic Ca'2+'-sensitizing effects of the mutations in human cardiac troponin I that causes restrictive cardiomyopathy
- Calpain activation is involved in the pressure overload-induced hypertrophy in the mouse heart
- Role of G.ALPHA.12/13 in pressure overload-induced cardiac hypertrophy
- The effects of olmesartan on in vitro model of cardiac hypertrophy of neonatal rat cardiomyocytes
- Role of orexin and co-transmitters in the defense response against stress
- Spinal .ALPHA.2-adrenergic and muscarinic receptors mediate the antiallodynic effect of supraspinally administered gabapentin
- Studies on pain control system(Rept.34): Involvement of spinal thrombin/platelet-derived growth factor(PDGF) pathway in the development of neuropathic pain-like state in mice
- Studies on pain control system(Rept.36): Possible mechanism of the suppression of the neuropathic pain-like state by gabapentin in mice
- Contribution of GABAergic systems on the pain-related behaviors in the mouse spinal cord
- Inhibitory effects of steroid hormones on DNA synthesis and proliferation in primary cultures of adult rat hepatocytes
- Identification of CD98 binding proteins and elucidate its physiological role in vivo
- Cdc42 and mDia3 regulate microtubule attachment to kinetochores
- Cross-linking CD98-mediates integrin signaling and tumorigenesis
- Cadherin expression in human liver cell line with 3D Radial- Flow culture system
- Reduction of mTOR activity by inhibited LAT1, the neutral amino acid transporter
- Role of C-terminus of the heterodimeric amino acid transporter family (SLC7) in membrane targeting
- A series of novel peptide-mimetic PAR-2 antagonists: inhibition of PAR-2-mediated signal transduction in human keratinocytes
- Glycogen synthase kinase-3.BETA.: molecular switch that directs up- and down-regulation of insulin receptor cell surface expression
- PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells
- Physiological significance of oligomerization of two thromboxane A2 receptor isoforms
- Phospholipid-protein interaction on the membrane determines a physiological mode of action of RGS proteins
- Diffrential coupling of .BETA.2-selective agonists with Gs, Gi and G16 proteins
- .BETA.-Arrestin2 enhances .BETA.2-adrenergic receptor-mediated nuclear translocation of ERK
- Adenosine A2A receptors localize in lipid rafts
- Stimulation of A1 receptor induces ATP release via an Ins(1,4,5)P3 sensitive-Ca'2+' pathway in MDCK cells
- Regulation of cytosolic phospholipase A2 activity by sphingolipids
- Spatial microenvironment defines Ca'2+' entry by muscarinic receptor stimulation in parotid acinar and duct cells
- Inhibition of UTP-induced inward currents by U-73122, 2APB and Xestospongin C in rat small pulmonary artery smooth muscle cells
- Involvement of chloride in apoptotic cell death induced by activation of P2X7 purinoceptor
- C-terminal splicing enhances physical interactions of cytoplasmic carboxy-termini of P2X receptors
- Effects of ACAT inhibitors and antioxidant on apoptosis/necrosis and lipid accumulation in foam cells exposed to oxidative stress
- Fenofibrate induces apoptosis in cultured human hepatocytes by inhibiting Akt phosphorylation
- Wogonin prevents dexamethasone-induced thymocyte apoptosis with no change in an antiimflammatory action
- Wogonin potentiates etoposide-induced apoptotic cell death in the tumor cells but not in the normal cells
- Involvement of glutathione-sensitive p38 MAPK activation in satratoxin H-induced apoptosis in PC12 cells
- Involvement of Bad on rotenone-induced apoptosis
- Caspase cascade proceeds rapidly at late stage in TNF-.ALPHA.-induced cell death machinery
- Application of semiempirical method for estimation of iron chelation and cytotoxic acitivty
- Cytotoxic activity of azulenequinones against human oral tumor cell lines
- Induction of tumor-specific cytotoxicity by doxorubicin, and relation to the expression of mdr1 mRNA
- Cytotoxic effects of tricyclic antidepressants on human colon adenocarcinoma cells in culture
- Differentiation-inducing factor-3 degrades cyclin D1 through the activation of glycogen synthase kinase-3.BETA. in HeLa cells
- Cell cycle regulation by novel nuclear protein Amida
- Induction mechanisms of angiogenesis stimulated by intercellular adhesion molecule-1 cross-linking
- An improved method for measuring acetylcholine(ACh), choline(Ch), phosphocholine(PhoCh), glycerophosphocholine(GlyCh) and phosphatidylcholine(PtdCh) in the same tissue sample by HPLC-ECD
- A lipid peroxidation product 4-hydroxynonenal modulates long-term potentiation in vitro and induces cell death via L-type Ca'2+' channel activation in the rat dentate gyrus
- NMDA receptor-dependent synaptic plasticity in amygdalo-hippocampal CA1 pathway in vivo
- Involvement of L-type Ca'2+' channel and Ca'2+'/calmodulin-dependent protein kinase II in the induction of long-term potentiation in the basolateral amygdala-dentate gyrus pathway of anesthetized rats
- Dual effects of hydrogen peroxide (H2O2) on hippocampal long-term potentiation; a study using a multichannel recording method
- Crocetin purified from Gardenia fruit prevents benzodiazepine-induced impairment of long-term potentiation in amygdalo-hippocampal synapses of anesthetized rat
- Basolateral amygdala 5-HT2C receptor modulates the induction of long-term potentiation in the dentate gyrus of anesthetized rats
- Serotonergic modulation of cocaine-induced behavioral sensitization in mice
- Analysis of serotonin neuron-specific gene expression induced by murine serotonin transporter promoter
- Mice strain differences in immobility time in the forced swimming test: involvement of serotonergic and noradrenergic neurons
- Serotonin 2 receptor is involved in increased immobility in the forced swim test in PACAP-deficient mice
- Methamphetamine-induced hyperthermia and lethality in dopamine and/or serotonin transporter knockout mice
- Edaravone, induced head-twitch response, altered central monoamine contents
- Effect of zotepine on extracellular monoamine levels in rat prefrontal cortex
- An animal model of depression: Influence of chronic infusion of dexamethasone on serotonin release in the amygdala and circadian rhythm of activity in rats
- Involvement of .ALPHA.1-adrenoceptor in the antidepressant-like effect of chlorpheniramine in the mouse tail suspension test
- New animal model of depression
- Facilitation of glutamate release by antidepressant drugs in rat locus coeruleus
- Effects of chronic administration of citalopram, a SSRI, on the noradrenaline release in the amygdala and the locus coeruleus
- Effects of SSRIs on immobility time in the forced swimming test: Studies using DBA/2 mice
- Effects of the serotonin2 receptor antagonists on anti-immobility effects of the dopamine reuptake inhibitor in mice
- Effects of chronic paroxetine treatment on serotonin transporters (SERT) in mouse brain
- Effect of antisense against organic cation transporter-3 on the forced swimming test in mice
- Inhibition by clorgyline, a monoamine oxidase A inhibitor, of methamphetamine-induced hyperlocomotion in mice through alteration of the serotonin turnover in the striatum
- Clorgyline, a monoamine oxidase A inhibitor, inhibits methamphetamine-induced behavioral sensitization in mice
- Effects of monoamine oxidase inhibitors on methamphetamine-induced stereotypies in mice
- Influence of amantadine and its related compounds on rat brain MAO activity and pharmacological behaviors in mice
- The differences between Wistar and Long-Evans rats in methamphetamine-induced locomotor activity and the expression organic cation trasporter-3
- Effects of dopamine- and serotonin-related compounds on methamphetamine-induced self-injurious behavior in mice
- The effects of antidepressants on hyper-emotionality of olfactory bulbectomized (O.B.) rats and their anxiety behaviors in the elevated plus-maze
- Weak power electromagnetic irradiation: Methodology for antidepressive effect study which used model rats
- The effect of paroxetine on enhanced contextual freezing induced by single prolonged stress (SPS) in rats
- Alterations in the serotonergic system in pre-pubertal mice with protein malnutrition
- Effects of early life stress on synaptic plasticity in the hippocampus of adult rats
- Early postnatal stress alters the emotional susceptibility to stress at postadolescent period of rats
- The mechanism for males recognizing females by olfaction
- The roles of histamine H3 receptors in methamphetamine sensitization
- Study of anti-inflammatory activity of H1 and H2 receptor gene knockout mice in formalin-induced nociceptive response
- Central three histamine receptors regulate cardiovascular function revealed by H1 and H2 receptors gene knockout mice
- Histamine H1 receptor gene knockout (H1KO) mice attenuates social isolation-induced disruption of prepulse inhibition (PPI)
- The different role of the histaminergic system for the regulatory mechanism of feeding by orexigenic peptides
- Changes of the feeding behavior and feeding-related neuropeptides mRNA in the NPY Y5R-KO mice
- The mesencephalic trigeminal nucleus is involved in the control of feeding and exploratory behavior
- The influences of long term feeding of high cholesterol diet on central nervous system in mice
- Involvement of TRPV4 in the central regulation of water intake
- Changes in emotional behavior of mice after olfactory bulbectomy in the hole-board test
- Anxiolytic- and antistress-like effects of rose oil contained aroma tape in the elevated plus maze test and the hole-board test in mice
- Effect of the anxiolytic tandospirone on sleep latency in rats
- Anxiolytic- and antidepressant-like effects of novel and potent nonpeptide antagonists of melanin-concentrating hormone receptor 1: ATC0065 and ATC0175
- ATC0065 and ATC0175: Novel and potent nonpeptide antagonists of melanin-concentrating hormone receptor 1
- Effects of glucagon-like peptide-2 on concussive brain injury-induced memory impairment
- Neuromedin U improves lipopolysaccharide-induced memory impairment in mice
- Repeated exposure to water impaired learning and memory in mice
- Effects of thioperamide and donepezil on learning and mnemonic deficits induced by pentylenetetrazol in weanling mice
- Regulation of dopamine/DARPP-32 signaling by glutamate in neostriatal neurons
- Effect of Ginkgo biloba extract on memory deficits of rats induced by some drugs in radial maze performance
- Effects of metabotropic glutamate receptor agonists on short-term memory impairment induced by domoic acid, an amnesic shellfish poison, in mice
- Effects of theanine injected into hippocampus on the learning to a negative patterning discrimination task in rats
- Nociceptin ameliorates learning and memory impairment by acting on ORL1 receptor-independent mechanisms
- Relationship between impairment of memory-related behavior and dopaminergic function in olfactory bulbectomized mice
- Thermogenetic mechanism of thyrotropin-releasing hormone (TRH) in Syrian hamsters: Roles of central TRH and dopamine system
- Role of monoamine re-uptake by cognate monoamine transporter
- Adaptation of pre- and post-synaptic dopaminergic signaling in methamphetamine-sensitized rats
- Specific inhibitory effect of antisense oligodeoxynucleotide against D2 dopamine receptor (D2R) on the dopamine receptor (DA R) mRNA expression in the striatum
- Dopamine D2 receptor-mediated stimulation of ['35'S]GTP.GAMMA.S binding in rat striatal membranes: Effects of dopaminergic agonists
- Chondroitin sulfate glycosaminoglycan E promotes the neurite outgrowth of dopaminergic neurons
- Effects of levodopa combined with a dopamine agonist on levodopa-induced apoptosis in 6-hydroxidopamine-lesioned mice
- Effect of 1-benzyl-1,2,3,4-tetrahydroisoquinoline on the striatal dopamine release in rat
- Possibility of nerve regeneration therapy on eating disorder
- Extrahypothalamic CRF activates the hypothalamic-pituitary-adrenal axis by activation of the noradrenergic system originated from locus coeruleus in rats
- Cholinergic oscillation in hippocampus of tottering calcium channel mutant mice
- Changes in the transcription factor activator protein-1 by drug-induced hearing loss in the guinea pig cochlea
- Gastric H'+',K'+'-ATPase expressed in cochlear lateral wall is critically involved in formation of endocochlear potential
- Substance P increases Ca'2+' sensitivity of pig iris sphincter muscle (ISM)
- The effects of antiglaucoma drugs on the function of ionotropic glutamate receptors
- Stimulation of corneal epithelial migration by a peptide corresponding to the PHSRN sequence of fibronectin
- The effects of gabapentin on K'+'-induced calcium influx in IMR32 human neuroblastoma cells, and the various types of neuropathic pain models in rats
- Anti-allodynic effect of FR140423, an orally active pyrazole derivative, in a rat model of postoperative pain: Role of .DELTA.-opioid receptors
- Changes of matrix metalloproteinase activities in spontaneously hypertensive hyperlipidemic rats
- Suppression by .BETA.-neurexin of VAMP2-EGFP accumulation in axon terminals of olfactory sensory neurons
- Analysis of desensitization and inactivation-like mechanism observed in channel pore mutants of P2X2 receptor
- Change of nicotinic receptor expression on an antigen-presenting cell (APC) line during the cell maturation
- Characterization of a single exocytotic event in digitonin-permeabilized adrenal chromaffin cells
- Stimulation of mitogen-activated protein kinase by environmental estrogenic pollutants through an estrogen receptor-independent pathway
- Involvement of peripheral glutamate receptor in nociception
- Amitriptyline improves the reduction of Kv3.3 mRNA in dorsal root ganglion of peripheral nerve-axotomized rats
- Roles of endothelin and its receptor subtypes in skin cancer pain in mice
- Spinal sensitization mechanism in streptozotocin-induced hyperalgesia in mice
- Functional analysis of purinoceptors in pain transmission with the Neurometer
- Beneficial actions of MM-101 on diabetic hypoalgesia and neuropathic pain
- Effect of oxycodone on thermal allodynia in diabetic mice
- The molecular mechanism of cold temparature recognition system
- Effect of daidzein on catecholamine synthesis in adrenal medulla
- Effect of resveratrol on catecholamine secretion in adrenal medullary cells
- Effects of protein tyrosine kinase inhibitors on catecholamine release in bovine adrenal chromaffin cells
- The value of local anesthetics on half-maximum inhibiting concentrations (IC50) of ACh-evoked or veratridine-evoked secretion of catecholamines from bovine adrenal chromaffin cells
- Distribution of NK-1, mu-opioid and NMDA receptors in laryngeal motoneurons in guinea pigs
- Comparative study of the response between naloxone and tetanic stimulation on isolated guinea-pig ileum followed by long exposure to morphine and bestatin
- Role of K'+' channels in prostanoid EP3 and TP receptors-mediated inhibition of noradrenaline release from the rat stomach
- Nitric oxide synthase (NOS) inhibition facilitates adrenergic neurotransmission in rat mesenteric resistance arteries
- Effects of AF-DX116 and other muscarinic receptor antagonists on orthostatic hypotension in the SART-stressed rats
- Increae in peripheral blood flow and production of parasympathetic predominance by the application of steam thermal sheets to the hips
- Effect of inhalation of cedrol on the autonomic activities (III)
- Effect of a selective ETA receptor antagonist YM598 on endothelin-1-induced bone formation
- Long-term observation of replanted rat molars pretreated with alendronate
- Studies on the application of a bisphosphonate, TRK-530, for periodontitis
- rhIL-11 does not affect the progression of tumor-induced osteolysis caused by bone metastases
- Expression of NK-1 receptors in synovial fibroblasts obtained from patients with rheumatoid arthritis
- PD-1 deficiency increases the potency of T cells to inhibit osteoclastogenesis
- ATP-stimulated interleukin-6 synthesis through P2Y receptors on human osteoblasts
- Proliferative response of human osteoblastic cells to interleukin-1.BETA.
- Expression of cystine/glutamate antiporter in primary cultured osteoclasts.
- Microfocus X-ray computer tomography analysis of microstructure in bone of nephrectomized rat
- Effects of mechanical strain on synovial cells
- Rise in the intracellular calcium concentration and proliferation of Gin-1 cells by isradipine
- Inhibition of angiotensin II- and endothelin-1-induced proliferation by EGF receptor kinase inhibitor in cultured rabbit gingival fibroblast
- Differential signaling pathways of EGF and FGF receptors regulate branching morphogenesis of fetal mouse submandibular glands
- Glycosphingolipids regulate osteoclastgenesis mediated by lipopolysaccharide
- Effects of indomethacin, prednisolone and methotrexate on the gene expression of inflammatory and osteoclastic differential inhibitory cytokines on type II collagen-induced arthritic rats
- Effect of celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, on bone loss of adjuvant-induced arthritic rats
- Effect of combined administration of menatetrenone and alendronate on bone mineral density in long-term phenytoin treated rats
- Inhibition of cartilage development by glutamate
- Expression of serine racemase in cultured rat costal chondrocytes
- Effects of prostaglandin D2 on blood pressure and heart rate
- Effect of .ALPHA.-adrenoceptor stimulation on Ca'2+' transients and Ca'2+' sensitivity in mouse ventricular cardiomyocytes
- EGCg, a major polyphenol in green tea, binds to cardiac troponin C and desensitizes cardiac muscle contraction to Ca'2+'
- Reduced beta-adrenergic response in the mouse whole hearts lacking PDK1
- Modified sympathetic response of cardiac muscle in mice lacking the voltage-dependent Ca'2+' channel .BETA.3 subunit
- Characterization of cardiac functions in transgenic mice overexpressing cardiac NCX1.1
- Gender-dependent difference in hypertensive phenotype in V1b receptor-deficient mice
- The effect of angiotensin II on endothelial nitric oxide synthase-deficient mice
- Establishment of the new experimental model of hot flushes and evaluation of the effect of serotonin reuptake inhibitor in ovariectomized mice
- Ovariectomy aggravates sildenafil-induced flushing of tail skin in mice
- Age-related changes in vasorelaxing effect of polyphenol compounds in rat aorta
- Urotensin II-stimulated production of prostaglandins and nitric oxide in coronary arteries of aged rats
- Effects of aging and elevated level of plasma triglyceride on blood pressure
- Beneficial effect of the AT1 receptor antagonist olmesartan on monocrotaline-induced pulmonary hypertension in rats
- Accumulated endogenous NOS inhibitors and accelerated arginase activity are involved in impairing the NO production in pulmonary hypertensive rats
- Effects of diesel exhaust exposure on natriuretic peptides and cytokines mRNA expressions in hearts of aged spontaneously hypertensive rats
- Beneficial effects of voluntary long-term exercise on blood pressure and vascular inflammation in stroke-prone SHR
- Improvement of impaired endothelial function by tetrahydrobiopterin infusion in stroke-prone spontaneously hypertensive rats
- Antihypertensive action mechanism of astaxanthin in SHR
- Involvement of AP-1 on the down regulation of catecholamine synthetic pathway by Rho kinase inhibitor in spontaneously hypertensive rats (SHR)
- Dosing-time-dependent effect of temocapril on the survival of stroke-prone spontaneously hypertensive rats
- Involvement of endothelin ETB receptor in gender differences of deoxycorticosterone acetate-salt-induced hypertension
- Participation of oxidative stress as a cardiovascular risk factor in rats with metabolic syndrome
- The changes of the protein expression in aorta of high fat diet loading spontaneously hypertensive hyperlipidemic rats with and sucrose-induced diabetes
- Effects of Ginkgo biloba extract in SHR/NDmcr-cp (cp/cp) rats
- Combined effects of a factor Xa inhibitor YM466 and a GPIIb/IIIa antagonist YM128 on thrombosis and neointima formation in mice
- Pharmacological properties of YM-254890, a specific G.ALPHA.q/11 inhibitor, on thrombosis and neointima formation in mice
- Biological properties of a specific G.ALPHA.q/11 inhibitor, YM-254890, on platelet functions and thrombus formation under high-shear stress
- Increase in plasma fibrinogen in spontaneously hypertensive rats (SHR) and hyperlipidemic rats (HLR)
- Effects of anti-Oketu drugs on platelet aggregation in normal human volnteer
- Study on anti-thrombotic activity of aspirin using ferric chloride-induced arterial thrombosis and tail resection models in rats
- BS-1417, a novel .ALPHA.v.BETA.3 integrin antagonist suppresses neointima formation after balloon injury in rats
- A kinetic analysis of neointima formation in rat balloon injury model: The active role of .ALPHA.v.BETA.3 integrin and the preventive role of endothelial cells regeneration
- A role of TNF-.ALPHA. for N'.EPSILON.'-(carboxymethyl)lysine-facilitated neovascularization of cultured choroidal explants in aged rat
- TGF-.BETA.1 enhances vascular tube formation of neural stem cells in three-dimensional culture
- Effects of lysophosphatidic acid on the migration and proliferation of vascular smooth muscle cells from porcine coronary artery
- Calcification in cultured rat aortic smooth muscle cells induced by calcification medium
- Anti-atherosclerotic effect of cilostazol in ApoE knockout mice
- Role of endogenous estrogen coexistent with apolipoprotein-E in the development of atherosclerosis under hypoxia
- Estrogen deficiency enhances NO-mediate response through increased activity of eNOS subsequent to a decrease in caveolin-1 and from induction of iNOS
- Enhanced intimal hyperplasia after ovariectomy (OVX) is effectively improved by estrogen replacement therapy (ERT) in the rat
- Ovariectomized female rats show more favorable response to atorvastatin than male rats against balloon injury
- Determination of epoxyeicosatrienoic acids in rabbit artery by LC/MS/MS method
- Nicardipine, a calcium antagonist, does not aggravate intracerebral hemorrhage in an intracerebral hemorrhage model in rats
- Cerebral ischemia decreases levels of tight junction proteins occludin and ZO-1, and enhances tyrosine phosphorylation of occludin in the cerebral microvessels
- A common index for quantifying gait disturbance induced by peripheral arterial insufficiency and arthritis in rats
- Protective effects of SAE0400 (SAE), a selective Na'+'-Ca'2+' exchange (NCE) inhibitor, on mitochondrial Na'+' or Ca'2+' uptake in relation to mitochondrial permeability transition pores (MPTP) and ischemia-reperfusion guinea-pig myocardial injury
- Protective effects of nicorandil against cardiac function and apoptosis in ischemia-reperfusion guinea-pig myocardial injury
- Protective effects of fluvoxamine, selective serotonin reuptake inhibitor (SSRI), against ischemia-reperfusion injury in guinea-pig hearts
- Effect of landiolol on myocardial dysfunction induced by ischemia/reperfusion of rats
- Preventice effect of Rho-kinase inhibitor Y-27632 on underperfusion-reperfusion injuries in diabetic rat hearts
- Comparison of protective effect of N-acetylcysteine on rat myocardial reperfusion injury by different treatment
- Effects of edaravone on the production of tumor necrosis factor alpha in myocardium and the release of adhesion molecules from myocardium after ischemia-reperfusion in isolated rat hearts
- Effects of ACEI and ARB on an increase in myocardial calpain of the rat with chronic heart failure following AMI
- The evaluation of cardiopathy by biochemical findings and the ultrasound diagnostic system in the myocardial infarction model rat
- Protective effect of taurine against doxorubicin-induced cardiotoxicity in mice
- Effects of taurine on adriamycin-induced heart failure
- Roles of prostanoids in pressure overload-induced cardiomyocyte hypertrophy and cardiac fibrosis in mice
- Dual role of endogenous nitric oxide (NO) in development of dextran sodium sulfate (DSS)-induced colitis in rats
- Roles of endogenous nitric oxide (NO) and prostaglandins (PGs) in alteration of gastric mucosal integrity in portal hypertensive rats
- The role of Helicobacter pylori infection and high salt diet in glandular stomach carcinogenesis and effect of eradication by lansoprazole in Mongolian gerbils
- Oxidative stress and its prevention by Terminalia catappa in galactosamine/lipopolysaccharide-treated iver of rats
- Effect of orange juice on expression of transporters in rat small intestine and liver
- Inhibitory effect of rugosa rose (Rosa rugosa Thunb.) extract on digestion of carbohydrates
- Anti-ulcer drug irsogladine prevents ischemia-reperfusion-induced gastric mucosal injury in rats
- Effect of milk whey culture with Propionibacterium freudenreichii ET-3 on the dextran sulfate-induced colitis in rats
- Effects of zinc supplementation on collagen and cell accumulation in pig serum-induced rat hepatic fibrosis
- Effect of capsaicin on gastric HCO3'-' secretion via primary afferent neurons and vanilloid receptors in rats and mice
- The preventive effect of Dai-kenchu-to on the postoperative adhesive intestinal obstruction in rats
- Mechanisms of Dai-kenchu-to in isolated guinea pig ileum: comparison with capsaicin
- Bitter taste transduction in the rat stomach
- Nitric oxide generation by ghrelin in the rat stomach
- Involvement of the down regulation of protease activated receptor-2 in the gastro-intestinal dysmotility of inflammatory bowel disease
- Modulation of visceral pain by PAR-2: antinociceptive/protective roles during pancreatitis and involvement in delayed colonic hyperalgesia
- The potent PAR-2 agonist 2-furoly-LIGRL-amide is a powerful and orally available gastric mucosal protective agent
- Pharmacological study on the autonomic innervation of the gastric and colonic muscularis mucosae isolated from human
- Muscarinic receptor subtype responsible for parasympathetic control of pancreatic exocrine secretion
- Effects of angiotensin II on liver regeneration
- Histopathological analysis for proliferative changes in upper digestive tract of rats given a single dose of alloxan
- FK506 ameliorates both steroid responsive and refractory colitis in IL-10 knockout mice
- Exogenous histamine stimulates colon cancer implant growth via immunosuppression in mice
- Relationship between gastrointestinal muscularis inflammation and dysmotility: Analysis in hapten-induced colitis model rat
- Role of PGD2/CRTH2 in LPS-inducible iNOS gene expression in ileal muscularis resident macrophages
- Intestinal dysmotility in a spontaneous Crohn's disease model mouse SAMP1/Yit
- Microarray analysis of clock-controlled gene in the mouse digestive organ
- Mode of action of AZD0865, a proton pump selective, potassium-competitive acid blocker (P-CAB)
- Functional characterization and tissue localization of SLC22 organic anion transporter OAT7
- Calcium-dependent and -independent signaling pathways are involved in thromboxane A2-induced fibroblast contraction in wound healing
- UV-induced ketoprofen radical and reactive oxygen species generation involved in photocontact deamatitis of topical ketoprofen
- Effect of apple polyphenols on pruritus behavior and IL-8 expression in pinna cells in ICR mice by inducing acidophil leukocyte permeation
- PPAR.GAMMA. ligand activity of ginkgolic acid-related compounds
- Enhanced adenosine-mediated inhibition of excitatory transmission in the central amygdala in the animal models of the neuropathic pain
- Spinal and peripheral analgesic action of the anticonvulsant zonisamide in the formalin test in mice
- Temporal and spatial patterns of microglia activation in the dorsal horn of neuropathic rats
- The analyses of the antinociceptive and rewarding effects of buprenorphine and tramadol in .MU.-opioid receptor knockout mice
- Supraspinal effects of pituitary adenylate cyclase-activating polypeptide (PACAP) on nociceptive transmission in mice
- Hyperglycemia in spinal cord contributes to mechanical hyperalgesia
- Studies on vasopressin receptors in nociceptive perception using vasopressin receptor deficient mice
- Antiallodynic effect and mechanism of Neurotropin in L5 spinal nerve ligation model of neuropathic pain
- Both spinal nitric oxide-cGMP pathway and free radicals mediate maintenance of neuropathic pain in mice
- Enhanced C-fiber-mediated wind-up following painful diabetic neuropathy in mice
- Antinociceptive effect of shakuyaku-kanzo-to in diabetic mice
- Studies on pain control system (Rept. 35): Neuropathic pain-like state increases anxiety-related behavior in mice
- Descending serotonergic and noradrenergic mechanisms mediate taltirelin-induced analgesic effects on acute thermal and mechanical nociception, respectively
- Spinal Ih channels mediate neuropathic pain
- Mechanisms of the antiallodynic effect of fluvoxamine in neuropathic pain mice
- Studies on pain control system (Rept. 37): Involvement of spinal interleukin-6 in the development of neuropathic, but not inflammatory, pain in mice
- Involvement of heme oxygenase in the protection of neuronal HT22 cells from oxidative stress
- Neuroprotective effect of minocycline on the cell death of retinal ganglion cells
- Glial-derived neurotrophic factor inhibits threo-hydroxyaspartate-induced motor neuron death in organotypic spinal cord slice culture from G93A SOD1 transgenic mice
- Hydrogen sulfide enhances the activity of K'+' and Cl'-' channels to protect cells from oxidative stress
- Oxidative neuronal death caused by glutamate uptake inhibition in cultured hippocampal neurons
- Role of PI3K-Akt pathway in response to endoplasmic reticulum stress-induced cell death
- Role of casein kinase 2 on endoplasmic reticulum stress responses
- Involvement of MAP kinase activation for the induction of Bip by 6-hydroxydopamine in human neuroblastoma SH-SY5Y cells
- Attenuation of neuronal damage by trimethyltin (TMT) in mice lacking PACAP (PACAP-KO)
- Behavioral changes by trimethyltin-induced dentate neural damage in mice
- Enhanced expression of DJ-1 by trimethyltin-induced dentate neural damage in mice
- Enhanced expression of doublecortin by TMT-induced dentate neural damage in mice
- Phosphorylation of ERK is involved in the protective effect of hepatocyte growth factor against neuronal cell death in the hippocampus after transient forebrain ischemia
- Roscovitine, a cyclin-dependent kinase inhibitor, reduces neuronal cell death induced by ischemia-reperfusion in the rat retina
- Effects of pentosan polysulphate on the ischemia-related neuronal death in the hippocampus
- Cortical hypoperfusion and its possible mechanisms in an animal model for attention-deficit/hyperactivity disorder
- Assessment of hyper accumulation around the lesion by FDG PET in primate thromboembolic stroke
- A monkey model of chronic stroke: Effects of rehabilitation
- Long-term effect of edaravone, a neuroprotective agent, on the functional outcome in a non-human primate model of stroke
- Neuroprotective effects of KCL-440, a new poly(ADP-ribose)polymerase inhibitor, on a rat model of middle cerebral artery occlusion
- Screening for control genes in rat global cerebral ischemia using GeneChip system
- Screening of control genes in mouse hippocampus after transient forebrain ischemia using high-density oligonucleotide array
- Relationship between angiogenesis and cell proliferation after transient forbrain ischemia in adult hippocampus
- Acetyl-L-carnitine transport in rat astrocytes is mediated by the organic cation/carnitine transporter OCTN2
- Effects of GLP-1 on LPS-induced cytokine expression in cultured astrocytes from the rat's cortex
- Effect of dibutyryl cyclic AMP on hydrogen peroxide-induced thymidine incorporation into cultured astrocytes
- Effects of bifemelane hydrochloride on the intracellular Ca'2+' level and ATP release of human origin clonal astrocytes
- Differential assembly of inwardly rectifying K'+' channel subunits, Kir4.1 and Kir5.1, in brain astrocytes
- Single channel analyses of the inhibition of 5-HT-induced currents by cloperastine
- The brain pericyte-derived transforming growth factor-beta (TGF-.BETA.) upregulates the blood-brain barrier function
- Cyclosporin A induces dysfunction of the blood-brain barrier by inhibiting adrenomedullin signal transduction in mouse brain endothelial cells
- Increase in aquaporin 1 expression by glucocorticoid in rat brain microvascular endothelial cells
- Manganese complexes of curcumin and diacetylcurcumin suppress NO production in the rat hippocampus: a microdialysis study
- Effects of nicotine on nucleotides release from hippocampus in ovariectomized rats
- Effects of selegiline on antioxidant enzymes in the nigrostriatum in rat
- Effect of edaravone on mitochondrial permeability transition pore in isolated rat brain mitochondria
- T-817MA, a neurotrophic compound, protects against sodium nitroprusside-induced toxicity in rat primary cultured neurons
- Altered level of glucocorticoid receptor within mitochondria by dexamethasone in murine brain
- Strain-dependent susceptibility to mitochondrial complex I inhibitors in mouse mesencephalic cultures
- Influences of the mRNA expression of amyloid precurser protein and the related factors in primaly cultured cortex cells
- F-1 isolated from a citrus fruit provides protection from memory impairment in Alzheimer's disease model rats
- Protective effect of donepezil against amyloid-beta neurotoxicity in rat septal neurons
- Effects of non-steroidal anti-inflamatory drugs on low-dose amyloid .BETA.-induced neurotoxicity in cultured rat hippocampal neurons
- ([Cl'-']i)-dependent amyloid .BETA. protein-induced glutamate neurotoxicity
- Protective effects of dihydrohonokiol-B against amyloid .BETA. protein-induced inhibition of neuronal Cl'-'-ATPase activity
- Amyloid .BETA. (25-35)/glutamate induced apoptosis via PI3K/GSK-3 signaling pathway in human neuroblastoma cell line
- Search for calcineurin B binding proteins by yeast two-hybrid system
- Automated, highly sensitive and quantitative in situ hybridization system for mRNA expressed in a single glial cell
- Analysis of MeCP2 expression in the central nervous system
- Neuronal expression of cFos protein in the sensory and motor pathways of spermine synthase deficient mice
- V-1 regulation of actin dynamics via an inhibition of actin capping activity by association between and CapZ in PC12D cells
- Drebrin A inhibits the actinbinding activity of caldesmon
- Effects of PKC and its related kinase, PKN on tau degradation
- RTAs, monoclonal antibodies to tau protein block tau aggregation
- Impaired cerebellar foliation of mice lacking kinase domain of FAK in nervous system
- Expression of histone deacetylase Sir2.ALPHA. in neural stem cells of adult mouse brain
- Differential effects of stromal cells on neural differentiation of embryonic stem (ES) cells
- p38 MAPK associates stereoselective priming by grepafloxacin on O2'-' production in neutrophils
- Comparison of the antioxidant activity of roasted tea with green, oolong, and black teas
- Effect of the dosing time on ticlopidine-induced hepatotoxicity in male, female and ovariectomized mice
- Evaluation of various drugs in a rat hyperlipemia model using the diagnostic ultrasound system
- Recombinant human histidine rich glycoprotein domains expressed in E. coli
- Human histidine rich glycoprotein binds to heme to inhibit the erythrolysis
- Hetero-oligomerization between purinergic receptors present in platelet membranes
- Effect of cilostazol on expression of CD40L and CD40 on activated platelet surface
- Nonsense-mediated mRNA decay of the intron-retained splice variant of GM-CSF receptor beta chain
- Inhibitory action of daunorubicin on iNOS expression in macrophages
- Distinction of sneeze and cough in guinea-pigs
- A newly developed late asthmatic response-model in mice
- A new method to quantify the airway mucin content in bronchio-alveolar lavage fluid
- Study on chronic obstructive pulmonary disease: Changes of the pulmonary function and lung histopathology in rats by cigarette smoke exposure
- Development of cigarette smoke solution (CSS) and lipopolysaccharide (LPS)-induced emphysema in guinea pigs
- Effects of various drugs on the electrically evoked cough reflex in conscious dogs
- YM-58483, a selective CRAC channel inhibitor, prevents late-phase asthmatic responses through Th2 cytokine inhibition in animal models
- Ovariectomy aggravates hypersensitivity reactions to paclitaxel in rats
- Pharmacological studies on the respiratory tract (Rept. 266): Transcriptional factors involved in the bronchial smooth muscle hyperresponsiveness in rat allergic asthma
- Pharmacological studies on the respiratory tract (Rept. 267): Contribution of NO to leukotriene D4-induced venodilation of nasal septal mucosa in nasal hyperresponsive rats
- Pharmacological studies on the respiratory tract (Rept. 269): New method for measuring venous response in mice nasal septal mucosa in vivo by stereomicroscopy
- Effects of new developed Chinese medicine on anti-asthma treatment in rats
- Effects of terpene alcohols, bisabolol and menthol, on the tracheal smooth muscle
- Regulation of K'+'channel expression and K'+' current by hypoxia in alveolar epithelial cells
- The roles of mast cells in compound 48/80 induced asthmatic respose
- Involvemant of Rho signaling in PAR-2-mediated increase in neutrophil adhesion to alveolar epithelial cells
- Induction of apoptosis and phosphorylation of H2B histone by the extracts of Sea buckthorn (Hippophae rhamnoides) seeds in Jurkat & HL-60 cells
- Possible correlation between MUC1 and TLR5
- Cellular signaling and induction of cyclooxygenase-2 caused by proteinase-activated receptor-2 (PAR-2) activation in human lung epithelial cells
- Crystalographic and pharmacological characterrization of HQL-79 as an orally active inhibitor for human hematopoietic prostaglandin D synthase
- Cytokine regulation of CysLT1 and CysLT2 receptor expression in the human monocytic leukemia cell line THP-1 cells
- Suppression of IgE-mediated TNF-.ALPHA. mRNA expression in heme oxygenase-1-induced RBL-2H3 cells
- Stimulatory effects of growth hormone on the differentiation of mouse B-lymphoid precursors
- Effect of tributyrin on oral tolerance
- M1 and M4, active components of ginseng saponin metabolites, promote maturation of dendritic cells and drive a potent Th1 polarization in vitro
- Characterization of mouse chymase
- Maintenance of cultured rat peritoneal mast cells via kit signal
- Heterologous autonomic regulation of histamine H1 receptor signaling
- Expression of COX-2 in dendritic cells of draining lymph nodes in rat carrageenin-induced pleurisy
- Inhibitory action of ethanol on ERK-mediated COX-2 expression in rat alveolar macrophages
- Phorbol 12-myristate-13-acetate (PMA) increases choline acetyltransferase (ChAT) activity in human leukemic T cell line MOLT-3
- Studies on regulation of lymphocytic cholinergic activity via DP receptor (DPR)-mediated pathways in MOLT-3 cells, using BW245C and ONO-PM-182
- Murine antigen-presenting cells express various subtypes of muscarinic and nicotinic acetylcholine receptor genes
- Effects of chronic nicotine (Nc) exposure on antibody production and nAChR .ALPHA.7 subunit gene expression in mononuclear leukocytes (MNLs) of BALB/c mice
- Lymphocytic cholinergic activity in senescence-accelerated mouse (SAM) with immune deficiency
- Potent inhibition of B cell receptor calcium signaling by novel pyrazole derivatives
- Physiological role and activation mechanism of the oxidative stress-susceptible TRPM2 Ca'2+' channel in immunocytes
- Analysis of BCR-induced calcium signaling in TRPC3-deficient DT40 cells
- Comparison study between the mechanisms of allergic asthma amelioration by a cysLT1R antagonist and steroid
- The beneficial or detrimental effects of an inducible NO synthase (iNOS) inhibitor on allergic airway inflammation depending on its administration schedule
- Cytoprotective effect of nitric oxide against hydrogen peroxide toxicity is mediated through the induction of catalase in RAW264 cells
- Activation of p38 MAP kinase induces conformational change of Bax in hydrogen peroxide-induced apoptosis in RAW264 cells
- Inhibition by Moxa smoke of prostaglandin E2 production in the activated macrophage-like cell line
- GLP (Good Laboratory Practice) for new drug application in Japan
- Modelling of the voltage-dependent inactivation process of L-type Ca'2+' channel
- Role of gonadal steroids on calcium currents for sex differences in guinea pig cardiac muscles
- The R(-)-enantiomer of efonidipine blocks T-type but not L-type calcium current in guinea-pig ventricular myocardium
- Effects of isoflurane on ATP-sensitive K'+' channels reconstituted in HEK293 cells
- Phosphorytation-independent modulation of a heart potassium channel by the A kinase-anchoring protein Yotiao
- Famotidine neither inhibits HERG K'+' current nor affects action potential parameters
- NIP-142 inhibits human GIRK1/4 current more potently than HERG current
- Investigation of the block and facilitation effects by nifekalant in a HERG channel
- Effects of changes in extracellular pH and potassium concentration on hERG current
- Difference of inhibitory effects on HERG potassium channel transfected in HEK 293 and CHO-K1 cells
- The inter-cell-line reproducibility of hERG assay using the whole-cell patch-clamping
- Determination of IC50 values for hERG blockers using an automated patch-clamp screening system
- Compound adsorption and the prevention measure in the automated patch-clamp assay
- Molecular identification and functional analysis of small-conductance Ca'2+'-activated K'+' channel in rat heart
- Identification of a novel specifec modulator of the L-type Ca'2+' channel Cav1.2
- TRPC5 is activated by endogenous NO through direct cystein oxidation
- Up-reguration of TRP channels in hypertrophied myocardium
- Genomic organization and functional analysis of murine PKD2L1
- Inhibitory effect of a novel benzyloxyphenyl derivative, SN-6 on Na'+'/Ca'2+' exchange current in single guinea-pig cardiac ventricular myocytes
- Involvement of Rho-GTPase in Na'+'/Ca'2+' exchanger mRNA stability in H9c2 cells
- Molecular cloning of the protein interacting with heart-restricted leucine-rich repeat protein, HRLRRP
- New evaluation of cardiac function in primate by real-time three-dimensional echocardiography as novel tools and methods for drug development
- Ex vivo application of ESR spectroscopy in Langendorff guinea-pig heart preparations
- A new monophasic action potential (MAP) recording system for the Langendorff-perfused heart
- Accurate evaluation of QT interval in conscious cynomolgus monkeys by use of telemetry ECG
- Monophasic action potential (MAP) recording with ventricular pacing is more reliable method than QTc measurement for the risk prediction of drug-induced QT prolongation in vivo
- Chronic atrioventricular block dogs as a model for predicting drug-induced torsades de pointes
- Characterization of halothane-anesthetized guinea pigs as a model to assay the drug-induced QT prolongation
- A Further study on evaluation of drugs inducing QT-interval prolongation by ECG recorded from the isolated guinea-pig perfused heart paced at the constant heart rate.
- Recording mono-phasic action potentials (MAP) from the surface of the anesthetized guinea-pig heart to evaluate drugs inducing QT-interval prolongation
- Anti-atrial fibrillatory profile of NIP-151, a novel agent that selectively prolongs atrial effective refractory period
- Effects of SEA0400, a novel sodium-calcium exchange inhibitor, on ouabain-induced arrhythmias in guinea pigs
- Blebbistatin blocks PDGF-induced migration of vascular smooth muscle cells
- Effect of non-kinase activity of myosin light chain kinase (MLCK) on smooth muscle myosin and its fragment
- High-level expression of a soluble and active form of full-length smooth muscle MLCK using cold-shock vector in Escherichia coli
- Identification of gap-junction in rat smooth muscle tissues
- A conceivable role in ATP release evoked by neurokinin A via Ins(1,4,5)P3 sensitive-Ca'2+' signaling from taenia coli smooth muscle cells
- A smooth muscle relaxant extracted from Physarum polycephalum
- Distribution of histamine H2-receptor and its participation in contraction in rat blood vessels
- The effects of aging on .ALPHA.1-adrenoceptor mechanisms in isolated mouse aortic preparation
- Relaxant effects of docosahexaenoic acid (DHA) on the vascular contractions in rat and guinea-pig arteries
- Forskolin-induced vasorelaxation involves Na'+'/Ca'2+' exchanger in mouse aorta
- Effects of an AMP-activated protein kinase (AMPK) activator on glucose uptake and lipid utilization in normal and Zucker-fatty rat hindlimb perfusion
- PAR-1 pepducins (intracellular agonist and antagonist): Distinct activity in multiple cells/tissues
- A novel peptide-mimetic PAR-2 antagonist K-14585: inhibition of PAR-2-agonist-mediated relaxation on isolated rat artery and increased vascular permeability in guinea pigs
- Hyper-contraction by the arachidonic acid of vascular smooth muscle
- Involvement of Rho/Rho-kinase pathway in endothelin-induced contraction in rat aorta and trachea
- Local Ca'2+' control and Ca'2+' wave during E-C coupling in mouse urinary bladder smooth muscle cells
- Changes in the mechanism of smooth muscle contraction in aged rat urinary bladders
- Capsaicin-induced, vanilloid receptor-independent relaxation in the guinea-pig ileum
- In vitro development of intestine-like tissue demonstrating rhythmic motility from embryonic mouse intestinal cells: role of bFGF
- Electrophysiological properties of isoforms of T-type Ca'2+' channel Cav3.2 expressed in human uterus
- Involvement of the endogenous prostaglandins in regulation of spontaneous contraction in non-pregnant porcine uterus
- Effects of Th1/2 cytokines on the contractility of airway smooth muscle cells
- .BETA.3-adrenoceptor mediating airway smooth muscle relaxation
- Pharmacological evidence that noradrenaline (NA)-elicited relaxation of tracheal smooth muscle is mediated through .BETA.-adrenoceptor (.BETA.-AR) subtypes distinct from established .BETA.1-3
- SP600125-sensitive pathway modulates airway smooth muscle contraction in guinea pigs
- Pharmacological studies on the respiratory tract (Rept. 268): Airway inflammation and bronchial smooth muscle hyperresponsiveness induced by chronic exposure to cigarette smoke
- Vanilloid receptor subtype 1 expressed in rat skeletal muscle
- Intracellular localization of Dysferlin in skeletal muscle
- Expression and characterization of full length myosin II
- .ZETA.-Sarcoglycan can replace .GAMMA.-sarcoglycan in the sarcoglycan complex formation
- Metabolic acidosis enhances the fibrate-induced myopathy
- Gene expression analysis of skeletal muscle from caveolin-3 knockout mice
- Herb derived substances, lignans are protecive against reactive oxygen species in murine skeletal muscle C2C12 cells
- A possible role of adrenomedullin during pregnancy in the rat
- Loss of body weight in mice lacking of taurine transporter
- Preparation and application of the mice model for studying urinary disturbances after cerebral infarction
- Prostaglandin receptors EP2, EP3, and IP mediate exudate formation in carrageenin-induced mouse pleurisy
- Influence of caffeine on the mRNA expression of type Ill iodothyronine deiodinase and thyroid hormone receptor in BeWo cell culture and rat placenta
- Influence of hypothermia on the pharmacokinetics and pharmacodynamics of propofol during cardiopulmonary bypass
- Effects of low concentration of tetrabromobisphenole A on cultured rat embryos
- Effects of continuous ingestion of herbal teas on midazolam pharmacokinetics in rats
- Response to endogenous and exogenous vasopressin V2 receptor stimulation is intact in mice lacking V1a or V1b receptors
- Endothelins participates the generation of pre-micturition contractions in rats with bladder outlet obstruction
- The effects of ET-1 and YM598, a novel selective endothelin ETA receptor antagonist, on the lower urinary tract
- The potency of a selective ETA receptor antagonist YM598 as a drug for renal diseases
- Effect of tamsulosin on involuntary bladder contractions in conscious rats with bladder outlet obstruction
- Effects of solifenacin succinate on voiding function in the experimental cerebral infarcted rats
- Tissue-selectivity of solifenacin succinate for urinary bladder over salivary gland in rats
- Bladder selectivity of anticholinergic drugs to treat overactive bladder by in vivo measurement of muscarinic receptors (mAChR) in mouse tissues
- Residual urinary concentrating ability in a rat models for chronic renal failure: Response to water restriction or subcutaneous dDAVP infusion
- Measurements of bladder function by conscious and unrestrained cystometry in the dysuria model rat
- Effect of methoctramine (Met) on urinary bladder contraction induced by the electrical stimulation (ES) of the pelvic nerve (PLN) in anesthetized rat
- The effects of flavoxate hydrochloride on the voltage-dependent L-type Ca'2+' currents in the human urinary bladder
- The channel pore protein of KATP channels in the human detrusor is mainly composed of Kir6.2
- A role of nitric oxide synthase in the gender difference of ischemic acute renal failure
- Preventive effect of moxonidine on ischemic acute renal failure in rats
- Mechanisms underlying chronic glomerular injury. Involvement of proteasome in disposal of aggregated protein in glomeruli
- Involvement of hyperglycemia with deposition of aggregated bovine serum albumin and processing in renal glomeruli Effects of alpha-glucosidase inhibitor
- Relationship between plasma mycophenolic acid and its glucuronide concentrations, and adverse effects in renal transplant patients
- Identification and functional characterization of a novel organic anion transporter OAT9
- Identification of the intracellular binding protein with proton-coupled oligopeptide transporter PEPT2 using yeast two-hybrid assay
- Gene expression profile in experimental mesangial proliferative glomerulonephritis
- Nuclear speckle localization of AGN-1 gene that is up-regulated in glomerulonephritis
- Expression and role of multi-drug resistant protein 1 (mdr1) in rat prostate
- Selective ETA receptor antagonist YM598 inhibits ET-1-induced cell signaling and cell growth in hormone refractory human prostate cancer cell line, PPC-1
- Overexpression of LAT1 and 4F2hc in clear cell RCCs and clinicopathological relevance LAT1
- Hepatocyte growth factor prevents NMDA-induced cell death through an ERK-dependent pathway in cultured hippocampal neurons
- NMDA-receptor prestimulation in the absence of extracellular calcium potentiates calcium influx-dependent neuronal cell death
- Modulation of NR1/NR2B-subtype NMDA receptor channels by SAP-102
- Effects of cyanide on synaptic transmission in rat hippocampal slices
- The protein kinase CK2 modulates the threshold of NMDA receptor-dependent synaptic plasticity
- Intra-arterial injection of microglia protects electrophysiological and morphological properties of hippcampal CA1 neurons against global ischemia
- Neuropharmacological characterization of HON0001, an orally active NMDA receptor NR2B subunit antagonist
- Involvement of brain arginine increase in glufosinate ammonium-induced delayed convulsion
- MK-801 upregulates the gene expression of D-serine-related enzymes in rat brain
- Roles of neuropeptides and peptidases in MK-801-treated schizophrenic model rat brain; effect of neuroleptics
- Chronic treatment with dibutyryl cAMP promotes L-glutamate-stimulated lactate release from cultured rat cortical astrocytes
- Mechanism of glutamate-induced neuronal cell death-Degradation of p27 by calpain and cell cycle reentry-
- Effects of LPS on glutamine transporter expressed in cultured cortical astrocytes
- Effect of AMPA receptor antagonist YM872 on cerebral hematoma size and neurological recovery in the intracerebral hemorrhage rat model
- Selective expression of heteromeric AMPA receptors
- Structural analysis of ATP-bindinq site of P2X receptor
- P2Y1 receptor-mediated Ca'2+' propagation in the hippocampus
- Pericyte-to-astrocyte communication via extracellular ATP
- Retinoic acid upregulates P2X4 receptor expression in microglia
- Role of fibronectin in the expression of P2X4 receptors in microglia and in pain signaling
- The physiological function of P2Y6 receptor in rat microglial cells
- The involvement of .BETA.1 integrin in microglial chemotaxis and proliferation on fibronectin: Regulation by P2Y12/13 receptor
- PLC-independent cation permeability activated by P2Y1 receptor in inhibitory interneurons in the rat hippocampus
- Nitric oxide downregulates lipopolysaccharide-induced expression of microsomal prostaglandin E2 synthase-1 in rat microglia
- Visualization of microglia in Iba1-EGFP transgenic mice
- Activation of rat nicotinic cholinergic system in the prelimbic cortex attenuates reinstatement of methamphetamine-seeking behavior
- Changes of nicotine and cotinine levels after cigarette smoke in the brain of spontaneously hypertenshive rats
- Effects of nicotine on stress stimulation: in vitro experiments
- Effects of nicotine on neural development and plasticity in the hippocampus
- Alkaloids indolizidine 235B' and (-)-pictamine block neuronal .ALPHA.4.BETA.2 nicotinic acetylcholine receptors
- PKC inhibits the deactivation of nicotinic acetylcholine receptor .ALPHA.4.BETA.2 subtype
- Role of acetylcholine and .ALPHA.-adrenergic receptors in the nucleus accumbens shell in rat turning behaviour
- Effects of allopregnanolone microinjected into the commissural subnucleus of the nucleus tractus solitarius on the chemoreceptor reflex in rat
- Effects of codeine on EPSCs in second-order neurons of the nucleus tractus solitarius in guinea pig brainstem slices
- Timing of synaphin/complexin binding to SNARE complex was probed by caged binding-site peptide
- Presynaptic TrkB receptors regulate short-term plasticity at the hippocampal CA3-CA1 synapses
- Disinhibition of hippocampal CA3 pyramidal cells due to proteolytic degradation of glutamate decarboxylase in cathepsin D-deficient mice
- Role of GABAA receptors in the substantia nigra pars reticulata in rat turning behaviour
- Effects of intrathecal baclofen on anemic decerebrate ridigity in rats
- Effect of diabetes on the zolpidem-induced sedation in mice
- Zonisamide at clinically relevant concentrations inhibits evoked EPSP but not presynaptic fiber volley in rat frontal cortex
- Sub-convolusive dosage of picrotoxin is ineffective for the diazepam-induced respiratory inhibition
- Constitutive secretion of BDNF leads to increase in presynaptic GAD65
- Alterations in expression of BDNF and plasma corticosterone level in the olfactory bulbecomized rats
- Repeated electroconvulsive stimuli increases brain-derived neurotrophic factor in ACTH-treated rats
- (-)-BPAP upregulates the expression of neurotrophins and bcl-2 in mesencephalic slice cultures
- Effect of (-)-1-(benzofuran-2-yl)-2-propylaminopentane on the expression of neurotrophins and superoxide dismutase 1 activity in midbrain slice cultures
- Studies on drug dependence (Rept. 404): Implication of brain-derived neurotrophic factor in methamphetamine-induced discriminative stimulant effect and hyperlocomotion in mice
- Effects of methamphetamine on neurogenesis in the adult mouse hippocampus
- A possibility of Leu-Ile as a novel therapeutic agent for methamphetamine-induced dependence
- Behaviral sensitization regimen with low doses of methamphetamine induces neurotoxic changes in the medial prefrontal cortex in rats
- The analysis of electrocardiogram with telemetry system in the rat: The effect of methamphetamine and thioperamide
- Effects of inhalation anesthetics and temperature on electron spin resonance spectra of spin labels in liposome
- The effects of general anesthetics on ESR spectra of spin labels located in different position in loposome
- Alterations in neuropeptide Y, CGRP and adrenomedullin receptor binding sites in animal model of schizophrenia
- A small hydrophobic dipeptide increases GDNF expression via transcription factor CREB in primary cultured neuron
- Cholecystokinin depolarizes orexin neurons via a CCKA receptor
- The effects on food intake of intracerebroventricular administration of neuropeptide B under surgical stress condition in mice
- Spinal substance P is involved in the vasopressin-induced central activation of adrenomedullary outflow in rats
- Contribution to nitric oxide and cyclooxygenases in substance P- or NMDA-induced nociceptive response
- Microglia-specific expression of microsomal prostaglandin E2 synthase-1 contributes to lipopolysaccharide-induced prostaglandin E2 production
- Prostaglandin E2 modulates midbrain dopaminergic system via its receptor EP1
- Naloxone-reversible anti-nociception produced by the injection of veratridine into rat brain
- Effects of opioid .DELTA.-receptor antagonist against emotional changes produced by stress stimuli
- Involvement of spinal nitric oxide in big dynorphin-induced nociceptive behavior
- Central mechanisms of natriuresis in different models
- Antipsychotics seen from computer chemistry
- A structure-activity relationship study for the effect of LSIGRL-NH2, a PAR-2-inactive control peptide, as a secretagogue for tear
- Effects of chlorinated oxidants on the conversion of xanthine dehydrogenase (XD) to oxidase (XO) in rat liver
- Effects of free fatty acids and fatty acyl-CoA esters on the activities of cyclooxygenase-1 and -2
- Glycogen synthase kinase-3: Up- and down-regulation of insulin receptor substrate-1/-2 expression
- Subcellular distribution of ACh-synthesizing activities in bamboo shoot (Phyllostachys bambusoides)
- Augmentation of neurotransmitter release resulted from the interaction of human alpha-1A adrenoceptor (HuA) with snapin
- The carboxy-terminus of the histamine H3 receptor interacts directly with a member of the intracellular chloride channel family
- Translocation of AQP5 and CLC-K2 in the interlobular ducts of rat parotid glands stimulated by M3 muscarinic receptors
- Effects of IP3 and heparin on the fluorescence ratio of the IP3 biosensor "LIBRA"
- Antitumor effect of amlodipine, a dihydropyridine Ca2+ channel blocker, on human epidermoid carcinoma A431 cells in vitro and in vivo
- Effect of bile acids on apoptosis induced by endoplasmic reticulum stress on isolated rat hepatocytes
- Partial purification of novel lectins from the dorsal spines of the reef stonefish, Synanceia verrucosa
- Establishment of ELISAs to quantify guinea pig total IgE and ovalbumin (OVA)-specific IgE
- Role of clock gene in cholesterol/cholic acid-induced changing in CYP7a gene expression in the mouse liver
- Pharmacokinetics of paroxetine and genotype of CYP2D6 polymorphisms in the Japanese patients with dose escalation
- CysLT2 signaling induces pro-apoptotic genes and apoptosis
- A NDN/MAGE-like gene in dictyostelium discoideum
- Identification of a splicing variant of rat Toll-like receptor 3 gene
- cDNA cloning and characterization of rat GPR120
- Gene expression analysis of short- and long-acting .BETA.2 adrenergic receptor agonists
- Gene expression profiling in rat liver treated with omeprazole-analysis of the data in the toxicogenomics project in Japan-
- Functional characterization of a novel cationic amino acid transporter (CAT5)
- Reconstitution into liposome of organic anion transporters
- Functional analysis of genetic variants of the human organic anion transporter, OAT (SLC22A6)
- Identification of a novel organic anion transporter OAT6 mediating carnitine transport in mouse liver and kidney
- Identification of a novel SLC7 family member Asc-2-like transporter in kidney
- Identification of a testis-type organic anion transporter 1 (TOAT1)
- Mechanism of substrate selectivity of human organic anion transporter 1
- Role of cysteine residues in the organic anion transporter mOAT1
- Promotor analysis of human carnitine transporter (OCTN2) gene
- A novel upregulator of carnitine transporter, OCTN2
- Identification of a novel brain-type organic anion transporter 1 (BOAT1)
- Association of TRPM2 channel with a novel EF-hand protein, EFHC1
- Purkinje cell-specific gene recombination mouse line generated from C57BL/6 strain ES cells
- Novel single nucleotide polymorphisms of .ALPHA.7 nicotinic receptor gene in Japanese schizophrenic patients
- E-cadherin is required for the gastrulation and the mophogenesis in zebrafish
- Curcumin induces glutathione S-transferase P1 via antioxidant response element
- Photochemical model of intrauterine growth retardation in pregnant mice
- Species-specific expression of microsomal prostaglandin E synthase-1 and cyclooxygenases in male monkey reproductive organs
- Stimulatory effects of eicosanoids on ovarian angiogenesis in early luteal phase in cyclooxygenase-II inhibitor-treated rats
- Inhibitory effects of amino compounds on wortmannin activities
- Evidence for paracrine modulation of voltage-dependent calcium channels in adrenal chromaffin cells
- Stimulatory effect of dehydroepiandrosterone sulfate ester on catecholamine secretion from bovine adrenal chromaffin cells
- Analysis for functional roles of vasopressin receptors in releasing adrenal hormones
- Analysis of vasopressin and oxytocin receptors in secreting glucagon from mouse pancreatic islets
- Preservation of .BETA.-cell function by DPP-IV inhibitor in ZDF rats
- Antidiabetic action of Bofu-tsusho-san in genetically diabetic mice (C57BL/KsJ-db/db mice)
- Effect of plant-derived essential oil, component and kampo prescriptions on plasma ACTH, catecholamine and LH levels in experimental menopausal rats
- ACTH releasing activity of KP-102 in rats is mainly mediated via release of CRF
- Adenylyl cyclase-cAMP system inhibits thrombin-induced HSP27 in vascular smooth muscle cells
- Transduction of Rac1/Cdc42-inhibitory protein down-regulated proteinase-activated receptor-1 and attenuated responsiveness to thrombin in human coronary artery smooth muscle cells
- Involvement of K+ and P450 metabolites but not H2O2 in decreasing the perfusion pressure with carbachol (CCh) in the rat hind limb
- Thrombin and trypsin potentiate myofilament Ca2+ sensitivity and induce contraction in pulmonary artery
- Mechanism decreasing peripheral vascular resistance with blackcurrant concentrate (BC)
- Mechanisms for vasodilating actions induced by quercetin in rat aorta
- Nucleotides release are related to an action of carvedilol in porcine coronary artery
- Characteristics of contraction-relaxation cycle of renal artery in ovariectomized rats
- Membrane depolarization-induced contraction and RhoA activation of rat caudal arterial smooth muscle involve genistein-sensitive tyrosine kinase
- Influence of endotoxemia on endothelium-dependen relaxation induced by acetylcholine and A-23187 in rat mesenteric arteries
- Calcium-independent PKC-DG kinase pathway is involved in a high glucose-induced dysfunction of mouse portal vein
- Alteration of mouse mesenteric artery contraction under high glucose condition
- Effect of blood pressure on Ephedra herb (Mao)-induced contracting and relaxing action in rat mesenteric artery
- Neural regulation of longitudinal smooth muscle in chicken posterior mesenteric artery
- Electrophysiological properties of excitatory junctional potentials in longitudinal smooth muscle of chicken anterior mesenteric artery
- Rho/Rho-kinase signaling-mediated contraction in aorta from apolipoprotein-E-deficient mice
- Relaxant effects of Y-27632 are more potent in K+ contraction than in norepinephrine contraction in the carotid artery from spontaneously hypertensive rats (SHR)
- Regional difference in the relaxant effects of Y-27632 on K+-contracted strips of femoral arteries from spontaneously hypertensive rats (SHR)
- Involvement of cysLT and LTB4 in vasopressin-induced contraction of rat basilar artery
- Influence of experimental SAH on effects of PLA2 and PLC inhibitors in nicotine-induced endothelium-dependent contraction (EDC) in rat basilar artery
- Enhanced reactivity of vasopressin in rat basilar arteries after subarachnoid hemorrhage
- Changes in K-channel and electrogenic sodium pump activities of rat basilar artery after SAH-induction
- Effects of cyclohexenonic long-chain fatty alcohol on STZ-induced diabetic rat aorta
- Possible involvement of angiotensin II in enhanced norepinephrine response in high-dose insulin treatment diabetic aorta
- Characterization of vasomotor activity in mesenteric artery from STZ-induced diabetic and cholesterol-fed mice
- Functional changes in adenylyl cyclases and associated decreases in relaxation responses in mesenteric arteries from diabetic rats
- Impaired vasomotor activity in isolated basilar artery from type II diabetic rats
- Attenuation of the cardiac function and calcium handling in streptozotocin (STZ)-induced diabetic mice
- Cardiovascular effects of mitiglinide calcium dehydrate: Comparison with glibenclamide and glimepiride (sulfonylureas)
- Effects of specific signal transduction inhibitors on increased permeability induced by neuropeptide Y or VEGF
- The interaction between nitric oxide and thromboxane A2 in cultured porcine basilar arterial endothelial cells
- Ca2+ response of endothelial cell at various regions in renal artery induced by shear stress in the presence of lysophosphatidic acid
- The effect of laminar shear stress on CYP1A1 expression and activity in vascular endothelial cells
- The membrane trafficking plays an important role in maintaining the surface expression of proteinase-activated receptor-1 in vascular smooth muscle cells
- RhoA plays a key role in regulating NO production in in situ endothelial cells
- Inhibition of RhoA expression by TGF.BETA.1 in bovine aortic endothelial cells
- Involvement of prostanoid(s) produced via the COX-1 pathway in NO-induced vasodilation of the rat eyegrounds
- Antagonizing effect of plasmin on the thrombin-induced endothelium-dependent relaxation in coronary artery
- Neuropeptide Y-induced potentiation of serotonin-mediated contraction in the porcine coronary artery: involvement of endothelium-generated thromboxane A2
- Neuropeptide Y-induced contraction and synergistic action in cerebral arteries and ciliary arteries
- NO-dependent cGMP production is downregulated through a type I angiotensin II receptor (AT1R)-mediated increase in superoxide production in rabbit mesenteric artery after long-term in vivo administration of nitroglycerine
- Chronic nitroglycerine administration reduces endothelial nitric oxide production in rabbit mesenteric resistance artery
- Vasoconstrictor rote and mRNA expression of each .ALPHA.1-AR subtype in mouse vessels
- Pharmacome analysis of .ALPHA.1L-adrenoceptor in rabbit ear artery
- Apelin-induced chemotaxic migration of retinal endothelial cells
1
- Amyloid Pathology and Protein Kinase C (PKC): Possible Therapeutics Effects of PKC Activators
- Physiology and Pathophysiology of Proteinase-Activated Receptors (PARs): Proteinases as Hormone-Like Signal Messengers: PARs and More
- Physiology and Pathophysiology of Proteinase-Activated Receptors (PARs): Role of Tryptase/PAR-2 in Vascular Endothelial Barrier Function
- Physiology and Pathophysiology of Proteinase-Activated Receptors (PARs): PARs in the Respiratory System: Cellular Signaling and Physiological/Pathological Roles
- Physiology and Pathophysiology of Proteinase-Activated Receptors (PARs): PAR-2-Mediated Proliferation of Colon Cancer Cell
- Physiology and Pathophysiology of Proteinase-Activated Receptors (PARs): Regulation of the Expression of PARs
- Physiology and Pathophysiology of Proteinase-Activated Receptors (PARs): PAR-2 as a Potential Therapeutic Target
- Transcription Factor Nrf2 Regulates Promoter Activity of Mouse Aldose Reductase (AKR1B3) Gene
- SCH00013, a Novel Ca2+ Sensitizer With Positive Inotropic and No Chronotropic Action in Heart Failure
- The Different Roles of 5-HT2 and 5-HT3 Receptors on Antinociceptive Effect of Paroxetine in Chemical Stimuli in Mice
- Lafutidine-Induced Increase in Intracellular Ca2+ Concentrations in PC12 and Endothelial Cells
- The N-Methyl-D-aspartate Receptor Antagonist Dizocilpine Inhibits Associative Antinociceptive Tolerance to Morphine in Mice: Relation With Memory
- Utilization of Human Liver Microsomes to Explain Individual Differences in Paclitaxel Metabolism by CYP2C8 and CYP3A4
- Participation of ATP in Nonadrenergic, Noncholinergic Relaxation of Longitudinal Muscle of Wistar Rat Jejunum
- The Antipsychotic and Antiemetic Drug Prochlorperazine Delays the Ventricular Repolarization of the In Situ Canine Heart
- Potentiation of T Cell Function by a Marine Algae-Derived Sulfated Polymannuroguluronate: In Vitro Analysis of Novel Mechanisms
- Exogenous Histamine Stimulates Colorectal Cancer Implant Growth via Immunosuppression in Mice
- Effect of Crude Saponin of Korean Red Ginseng on High-Fat Diet-Induced Obesity in the Rat
- Increased Excretion of Urinary 20-HETE in Rats With Cyclosporine-Induced Nephrotoxicity
- Induction of Apoptosis by Korean Medicine Gagam-whanglyun-haedoktang Through Activation of Caspase-3 in Human Leukemia Cell Line, HL-60 Cells
- Ability of Fourteen Chemical Agents Used in Dental Practice to Induce Chromosome Aberrations in Syrian Hamster Embryo Cells
- Monitoring Expression of Cytochrome P450 Genes During Postischemic Rat Liver Reperfusion Using DNA Microarrays
2
- Drug Dependence, Synaptic Plasticity, and Tissue Plasminogen Activator
- Nuclear Receptors as Targets for Drug Development: Molecular Mechanisms for Regulation of Obesity and Insulin Resistance by Peroxisome Proliferator-Activated Receptor .GAMMA., CREB-Binding Protein, and Adiponectin
- Nuclear Receptors as Targets for Drug Development: The Role of Nuclear Receptors During Neural Stem Cell Proliferation and Differentiation
- Nuclear Receptors as Targets for Drug Development: Regulation of Cholesterol and Bile Acid Metabolism by Nuclear Receptors
- Nuclear Receptors as Targets for Drug Development: Crosstalk Between Peroxisome Proliferator-Activated Receptor .GAMMA. and Cytokines in Bone Marrow-Derived Mesenchymal Stem Cells
- Nuclear Receptors as Targets for Drug Development: Peroxisome Proliferator-Activated Receptor .GAMMA. in Mast Cells: Its Roles in Proliferation and Differentiation
- Enhanced Wind-Up of the C-Fiber-Mediated Nociceptive Flexor Reflex Movement Following Painful Diabetic Neuropathy in Mice
- Proteasome Inhibitors Protect Against Degeneration of Nigral Dopaminergic Neurons in Hemiparkinsonian Rats
- Ca2+-Dependent Induction of Intracellular Ca2+ Oscillation in Hippocampal Astrocytes During Metabotropic Glutamate Receptor Activation
- Sargassum hemiphyllum Inhibits Atopic Allergic Reaction via the Regulation of Inflammatory Mediators
- A New Technique With Calcium Phosphate Precipitate Enhances Efficiency of In Vivo Plasmid DNA Gene Transfer
- Nephrin and Podocin Expression Around the Onset of Puromycin Aminonucleoside Nephrosis
- A Potent Apoptosis-Inducing Activity of a Sesquiterpene Lactone, Arucanolide, in HL60 Cells: a Crucial Role of Apoptosis-Inducing Factor
- Chinese Herbal Medicine, Shengmai San, Is Effective for Improving Circulatory Shock and Oxidative Damage in the Brain During Heatstroke
- Effects of First- and Second-Generation Histamine-H1-Receptor Antagonists on the Pentobarbital-Induced Loss of the Righting Reflex in Streptozotocin-Induced Diabetic Mice
- Comparison of Toxicity and Toxicokinetics/Pharmacokinetics of an .ALPHA.1L-Adrenoceptor Agonist in Rats and Rhesus Monkeys
- An Improved and Reliable Method for the Induction of Colitis in Rats Using 2,4,6-Trinitrobenzene Sulfonic Acid
- Recovery of Focal Brain Ischemia-Induced Behavioral Dysfunction by Intracerebroventricular Injection of Microglia
- Cytotoxic Effect of the Her-2/Her-1 Inhibitor PKI-166 on Renal Cancer Cells Expressing the Connexin 32 Gene
- Reduction of GTP Cyclohydrolase I Feedback Regulating Protein Expression by Hydrogen Peroxide in Vascular Endothelial Cells
3
- Roles of the Receptor for Advanced Glycation Endproducts in Diabetes-Induced Vascular Injury
- Mitochondrial Dysfunction, Endoplasmic Reticulum Stress, and Apoptosis in Alzheimer's Disease
- The Role of Sigma Receptors in Depression
- Functional Proteins Involved in Regulation of Intracellular Ca2+ for Drug Development: Pharmacology of SEA0400, a Specific Inhibitor of the Na+-Ca2+ Exchanger
- Functional Proteins Involved in Regulation of Intracellular Ca2+ for Drug Development: Chronic Nicotine Treatment Upregulates L-Type High Voltage-Gated Calcium Channels
- Functional Proteins Involved in Regulation of Intracellular Ca2+ for Drug Development: Desensitization of N-Methyl-D-aspartate Receptor Channels
- Functional Proteins Involved in Regulation of Intracellular Ca2+ for Drug Development: Role of Calcium/Calmodulin-Dependent Protein Kinases in Ischemic Neuronal Death
- Functional Proteins Involved in Regulation of Intracellular Ca2+ for Drug Development: The Extracellular Calcium Receptor and an Innovative Medical Approach to Control Secondary Hyperparathyroidism by Calcimimetics
- Simultaneous Real-Time Detection of Initiator- and Effector-Caspase Activation by Double Fluorescence Resonance Energy Transfer Analysis
- Nitric Oxide Induces Apoptosis in Mouse C2C12 Myoblast Cells
- CB1 Cannabinoid Receptor Stimulation Modulates Transient Receptor Potential Vanilloid Receptor 1 Activities in Calcium Influx and Substance P Release in Cultured Rat Dorsal Root Ganglion Cells
- Effects of AF-DX116 and Other Muscarinic Receptor Antagonists on Orthostatic Hypotension in Autonomic Imbalanced (SART-Stressed) Rats
- Antiarrhythmic Properties of a Prior Oral Loading of Amiodarone in In Vivo Canine Coronary Ligation/Reperfusion-Induced Arrhythmia Model: Comparison With Other Class III Antiarrhythmic Drugs
- Changes in pH Increase Perfusion Pressure of Coronary Arteries in the Rat
- Effects of Growth Hormone on the Differentiation of Mouse B-Lymphoid Precursors
- Receptor Subtypes Mediating the Inotropic Effects and Ca2+ Signaling Induced by Endothelin-1 Through Crosstalk With Norepinephrine in Canine Ventricular Myocardium
- Mechanisms of Analgesic Action of Neurotropin on Chronic Pain in Adjuvant-Induced Arthritic Rat: Roles of Descending Noradrenergic and Serotonergic Systems
- Ameliorative and Exacerbating Effects of [pGlu4,Cyt6]AVP(4-9) on Impairment of Step-Through Passive Avoidance Task Performance by Group II Metabotropic Glutamate Receptor-Related Drugs in Mice
- Study on Action Mode of Sphingosine 1-Phosphate in Rat Hepatocytes
- Effect of Antibodies Against Intercellular Adhesion Molecule-1, B7, and CD40 on Interleukin-18-Treated Human Mixed Lymphocyte Reaction
- Characterization of N6-Cyclohexyladenosine-Induced Hypothermia in Syrian Hamsters
- Proteasome Function and Pathological Proteins in the Pathogenesis of Parkinson's Disease
- Does Proteosome Inhibition Decrease or Accelerate Toxin-Induced Dopaminergic Neurodegeneration?
4
- Pathophysiological Roles of Amyloidogenic Carboxy-Terminal Fragments of the .BETA.-Amyloid Precursor Protein in Alzheimer's Disease
- Clinical and Experimental Evidence for Prevention of Acute Renal Failure Induced by Radiographic Contrast Media
- A Theoretical Method for Normalizing Total Serum Valproic Acid Concentration in Hypoalbuminemic Patients
- Roles of SIRT1 and Phosphoinositide 3-OH Kinase/Protein Kinase C Pathways in Evodiamine-Induced Human Melanoma A375-S2 Cell Death
- Involvement of Adenosine A2a Receptor in Intraocular Pressure Decrease Induced by 2-(1-Octyn-1-yl)adenosine or 2-(6-Cyano-1-hexyn-1-yl)adenosine
- Characterization of Forskolin-Induced Ca'2+' Signals in Rat Olfactory Receptor Neurons
- Naltrexone Protects Against Hypotension, Hyperthermia, and .BETA.-Endorphin Overproduction During Heatstroke in the Rat
- Altered Brain Penetration of Diclofenac and Mefenamic Acid, but Not Acetaminophen, in Shiga-Like Toxin II-Treated Mice
- Angiogenesis Inhibitor Z24 Induces Endothelial Cell Apoptosis and Suppresses Tumor Growth and Metastasis
- Hepatoprotective Effect of Tectoridin and Tectorigenin on tert-Butyl Hyperoxide-Induced Liver Injury
Supplement 1
98
- Shengmai San, a Chinese Herbal Medicine Protects Against Rat Heat Stroke by Reducing Inflammatory Cytokines and Nitric Oxide Formation
- Effects of a Novel Cyclohexane Dicarboximide Derivative, ST-6, on Reperfusion-Induced Arrhythmia in Rats
- (+)-Catechin, an Ingredient of Green Tea, Protects Murine Microglia From Oxidative Stress-Induced DNA Damage and Cell Cycle Arrest
- Modification of .KAPPA.-Opioid Receptor Agonist-Induced Antinociception by Diabetes in the Mouse Brain and Spinal Cord
- Atria Selective Prolongation by NIP-142, an Antiarrhythmic Agent, of Refractory Period and Action Potential Duration in Guinea Pig Myocardium
- Pepsin-Digested Bovine Lactoferrin Induces Apoptotic Cell Death With JNK/SAPK Activation in Oral Cancer Cells
- Cephaloridine Induces Translocation of Protein Kinase C .DELTA. Into Mitochondria and Enhances Mitochondrial Generation of Free Radicals in the Kidney Cortex of Rats Causing Renal Dysfunction
- Corymine Potentiates NMDA-Induced Currents in Xenopus Oocytes Expressing NR1a/NR2B Glutamate Receptors
- Detailed Pharmacological Characterization of 5-HT1A-Receptor-Mediated ['35'S]GTP.GAMMA.S Binding in Rat Hippocampal Membranes
- The Cannabinoid Receptor Agonist WIN 55212-2 Inhibits Neurogenic Inflammations in Airway Tissues
- Differences in .ALPHA.1-Adrenoceptor Subtype-Mediated Vasoconstriction by Tyramine and Nerve Stimulation in Canine Splenic Artery
- Prostaglandin D2 Inhibits IgE-Mediated Scratching by Suppressing Histamine Release From Mast Cells
- Effect of L-NAME on the Synthesis of Plasma Fibrinogen in Mice
- Abrogation of Bronchial Eosinophilic Inflammation and Attenuated Eotaxin Content in Protease-Activated Receptor 2-Deficient Mice
- Inhibitory Action of 5-HT1A Agonist MKC-242 on Triazolam-Induced Phase Advances in Hamster Circadian Activity Rhythms
2
- Butorphanol: Effects of a Prototypical Agonist-Antagonist Analgesic on .KAPPA.-Opioid Receptors
- Nitric Oxide-Induced Nitrative Stress Involved in Microbial Pathogenesis
- A Novel Src Kinase Inhibitor, M475271, Inhibits VEGF-Induced Human Umbilical Vein Endothelial Cell Proliferation and Migration
- Cytoprotective Effect of 3-[2-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole Dihydrochloride 3.5 Hydrate (DY-9760e) Against Ischemia/Reperfusion-Induced Injury in Rat Heart Involves Inhibition of Fodrin Breakdown and Protein Tyrosine Nitration
- Nitric Oxide Inhibits the Bradykinin B2 Receptor-Mediated Adrenomedullary Catecholamine Release but Has No Effect on Adrenal Blood Flow Response In Vivo
- Effects of Rikkunshi-to, a Traditional Japanese Medicine, on the Delay of Gastric Emptying Induced by N'G'-Nitro-
L -arginine - Caveolae-Independent Activation of Protein Kinase A in Rat Neonatal Myocytes
- Loperamide Inhibits Tachykinin NK3-Receptor-Triggered Serotonin Release Without Affecting NK2-Receptor-Triggered Serotonin Release From Guinea Pig Colonic Mucosa
- Mechanisms Involved in the Contraction of Intrahepatic Portal Vein Branches by Clomipramine and Oxethazaine in Isolated Perfused Rat Livers
- Baicalein Prevents 6-Hydroxydopamine-Induced Dopaminergic Dysfunction and Lipid Peroxidation in Mice
3
- Hippocampus-Dependent Memory Formation: Do Memory Type-Specific Mechanisms Exist?
- Transcriptional Regulation of Neuronal Genes and Its Effect on Neural Functions: Preface
- Transcriptional Regulation of Neuronal Genes and Its Effect on Neural Functions: NAD-Dependent Histone Deacetylase SIRT1 (Sir2.ALPHA.)
- Transcriptional Regulation of Neuronal Genes and Its Effect on Neural Functions: Expression and Function of Forkhead Transcription Factors in Neurons
- Transcriptional Regulation of Neuronal Genes and Its Effect on Neural Functions: Cumulative mRNA Expression of PACAP and BDNF Genes Controlled by Calcium and cAMP Signals in Neurons
- Transcriptional Regulation of Neuronal Genes and Its Effect on Neural Functions: Gene Expression in Response to Static Magnetism in Cultured Rat Hippocampal Neurons
- Transcriptional Regulation of Neuronal Genes and Its Effect on Neural Functions: Transcriptional Regulation of Neuropeptide Y Gene by Leptin and Its Effect on Feeding
- Long-Term Effects of High Doses of Nicotine on Feeding Behavior and Brain Nitric Oxide Synthase Activity in Female Mice
- Spatial Learning of Mice Lacking a Neuron-Specific Epidermal Growth Factor Family Protein, NELL2
- Upregulation of Phospholipase D Expression and Activation in Ventricular Pressure-Overload Hypertrophy
- The Effect of Herbal Medicine Toki-shakuyaku-san on Blood Pressure in an N'.OMEGA.'-Nitro-
L -Arginine Methyl Ester-Induced Pre-eclampsia Rat Model During Pregnancy and the Postpartum Period - Mediators Involved in Decreasing Peripheral Vascular Resistance With Carbachol in the Rat Hind Limb Perfusion Model
- Inhibitory Mechanism of Papaverine on Carbachol-Induced Contraction in Bovine Trachea
- Angiotensin Blockade Inhibits Osteopontin Expression in Non-infarcted Myocardium After Myocardial Infarction
- Establishment of Rat Model of Drug-Induced Gingival Overgrowth Induced by Continuous Administration of Phenytoin
- SKI306X Suppresses Cartilage Destruction and Inhibits the Production of Matrix Metalloproteinase in Rabbit Joint Cartilage Explant Culture
- Enhanced Learning of Normal Adult Rodents by Repeated Oral Administration of Soybean Transphosphatidylated Phosphatidylserine
- A Simple In Vivo Atrial Fibrillation Model of Rat Induced by Transesophageal Atrial Burst Pacing
- Molecular Cloning of Monkey Histamine H4 Receptor
- Forced Exercise-Induced Flushing of Tail Skin in Ovariectomized Mice, as a New Experimental Model of Menopausal Hot Flushes
- Ephedorae herba Decreases Lipopolysaccharide-Induced Cyclooxgenase-2 Protein Expression and NF-.KAPPA.B-Dependent Transcription in C6 Rat Glioma Cells
4
- Quantifying Receptor Properties: the Tissue Segment Binding Method - a Powerful Tool for the Pharmacome Analysis of Native Receptors
- The High Atherosclerotic Risk Among Epileptics: the Atheroprotective Role of Multivitamins
- Noise-Stress-Induced Brain Neurotransmitter Changes and the Effect of Ocimum sanctum (Linn) Treatment in Albino Rats
- Activation of Phosphoinositide 3-Kinase, Protein Kinase C, and Extracellular Signal-Regulated Kinase Is Required for Oridonin-Enhanced Phagocytosis of Apoptotic Bodies in Human Macrophage-Like U937 Cells
- Beneficial Effect of Candesartan on Rat Diastolic Heart Failure
- Effect of Oral Immunotherapy on Nasal Blockage in Experimental Allergic Rhinitis
- Simple and Noninvasive Breath Test Using '13'C-Acetic Acid to Evaluate Gastric Emptying in Conscious Rats and Its Validation by Metoclopramide
- Antiemetic Activity of FK1052, a 5-HT3- and 5-HT4-Receptor Antagonist, in Suncus murinus and Ferrets
- Effects of KB-R9032, a new Na'+'/H'+' Exchange Inhibitor, on Canine Coronary Occlusion/Reperfusion-Induced Ventricular Arrhythmias
- Novelty Stress Increases Fecal Pellet Output in Mongolian Gerbils: Effects of Several Drugs
- Effects of 5-HT1A-Receptor Agonist, 8-OH-DPAT, and GABAB-Receptor Agonist, Baclofen, on Lordosis in Female Rats With Lesions in Either the Dorsal Raphe Nucleus or Septum
- Facilitation of L-type Ca'2+' Currents by Fluid Flow in Rabbit Cerebral Artery Myocytes
- Thromboxane A2 Up-Regulates Neutrophil Elastase Release in Syrian Hamsters With Trinitrobenzene Sulfonic Acid-Induced Colitis
- Effects of [5-(2-Methoxy-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32560), a Novel Sodium/Hydrogen Exchanger-1 Inhibitor, on Myocardial Infarct Size and Ventricular Arrhythmias in a Rat Model of Ischemia/Reperfusion Heart Injury
- Mast Cell Tryptase Stimulates DLD-1 Carcinoma Through Prostaglandin- and MAP Kinase-Dependent Manners
- Maternal Alcohol Administration Suppresses Expression of Nitric Oxide Synthase in the Hippocampus of Offspring Rats
- Nafamostat Mesilate Induces Production of Interleukin-12 and -18 in Human Peripheral Blood Mononuclear Cells
- The mRNA Expression Differences of RNA Editing Enzymes in Differentiated and Undifferentiated NG108-15 Cells
1
99
- Genetic Approaches to the Molecular/Neuronal Mechanisms Underlying Learning and Memory in the Mouse
- The Kallikrein-Kinin System: Current and Future Pharmacological Targets
- Antifungal Activities of Propolis Collected by Different Races of Honeybees Against Yeasts Isolated From Patients With Superficial Mycoses
- Granulocyte-Colony Stimulating Factor Augments Neovascularization Induced by Bone Marrow Transplantation in Rat Hindlimb Ischemia
- Involvement of Supraspinal Imidazoline Receptors and Descending Monoaminergic Pathways in Tizanidine-Induced Inhibition of Rat Spinal Reflexes
- Augmentation of .ALPHA.1-Adrenoceptor-Mediated Contraction by Warming Without Increased Phosphorylation of Myosin in Rat Caudal Arterial Smooth Muscle
- Selective Inhibition of Inducible Nitric Oxide Synthase Attenuates Renal Ischemia and Damage in Experimental Heatstroke
- Mechanisms of Capsaicin- and Citric-Acid-Induced Cough Reflexes in Guinea Pigs
- Antipruritic Effect of Ginsenoside Rb1 and Compound K in Scratching Behavior Mouse Models
- Effect of Etidronate on Aortic Calcification and Bone Metabolism in Calcitoriol-Treated Rats With Subtotal Nephrectomy
- Preferable Anesthetic Conditions for Echocardiographic Determination of Murine Cardiac Function
- Evidence for a Specific Intracellular Localization of an Antisense Oligonucleotide in K562 Cells
- Aminophylline Pretreatment Modulates the Nitric Oxide System of the Isolated Rat Diaphragm: the Role of Frequency of the Electrical Stimulation
- Docosahexaenoic Acid Enhances Cyclooxygenase-2 Induction by Facilitating p44/42, but Not p38, Mitogen-Activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells
- Growth Hormone Releaser Attenuates .BETA.-Amyloid (1 - 42)-Induced Memory Impairment in Mice
2
- Regulated Expression and Function of the Somatodendritic Catecholamine Neurotransmitter Transporters
- New Twist on Neuronal Insulin Receptor Signaling in Health, Disease, and Therapeutics
- Cellular and Molecular Mechanisms of Immuno-modulation by Ganoderma lucidum
- Perospirone, a Novel Antipsychotic Drug, Inhibits Marble-Burying Behavior via 5-HT1A Receptor in Mice: Implications for Obsessive-Compulsive Disorder
- Sphingosylphosphorylcholine Antagonizes Proton-Sensing Ovarian Cancer G-Protein-Coupled Receptor 1 (OGR1)-Mediated Inositol Phosphate Production and cAMP Accumulation
- Underlying Mechanism of Combined Effect of Methamphetamine and Morphine on Lethality in Mice and Therapeutic Potential of Cooling
- Inhibitory Effect of Thiopental on Ultra-rapid Delayed Rectifier K'+' Current in H9c2 Cells
- Halothane Sensitizes the Guinea-Pig Heart to Pharmacological IKr Blockade: Comparison With Urethane Anesthesia
- Dehydroepiandrosterone Sulfate Reduces Acoustic Injury of the Guinea-Pig Cochlea
3
- Pathophysiological Significance of T-type Ca'2+' Channels: Preface
- Pathophysiological Significance of T-type Ca'2+' Channels: Properties and Functional Roles of T-type Ca'2+' Channels in Cardiac Pacemaking
- Pathophysiological Significance of T-type Ca'2+' Channels: Expression of T-type Ca'2+' Channels in Fetal and Diseased Heart
- Pathophysiological Significance of T-type Ca'2+' Channels: Transcriptional Regulation of T-type Ca'2+' Channel - Regulation of CACNA1H by Neuron-Restrictive Silencer Factor
- Pathophysiological Significance of T-type Ca'2+' Channels: T-type Ca'2+' Channels and Drug Development
- Pathophysiological Significance of T-type Ca'2+' Channels: Role of T-type Ca'2+' Channels in Renal Microcirculation
- Tachykinin Agonists Modulate Cholinergic Neurotransmission at Guinea-Pig Intracardiac Ganglia
- Identification and Expression of Frizzled-3 Protein in Rat Frontal Cortex After Antidepressant and Electroconvulsive Treatment
- A Newly Derived Protein From Bacillus subtilis natto With Both Antithrombotic and Fibrinolytic Effects
- Thrombin-Induced Force Development in Vascular Endothelial Cells: Contribution to Alteration of Permeability Mediated by Calcium-Dependent and -Independent Pathways
- Effect of Adrenomedullin on Adrenergic Vasoconstriction in Mesenteric Resistance Arteries of the Rat
- Comparative Effects of Indomethacin and Nabumetone on Urine and Electrolyte Output in Conscious Rats
- Effects of Anti-Nerve Growth Factor Antibody on Symptoms in the NC/Nga Mouse, an Atopic Dermatitis Model
- Increase in the Deposition of Aggregated Protein in the Glomeruli of Spontaneously Diabetic Mice
- Reduction of Atherosclerosis in Cholesterol-Fed Rabbits and Decrease of Expressions of Intracellular Adhesion Molecule-1 and Vascular Endothelial Growth Factor in Foam Cells by a Water-Soluble Fraction of Polygonum multiflorum
4
- Transcriptional Factors in the Cochlea Within the Inner Ear
- Lithium: Potential Therapeutics Against Acute Brain Injuries and Chronic Neurodegenerative Diseases
- Effect of Antiepileptic Drugs on the Urinary Excretion of Porphyrins in Non-porphyric Subjects
- Milk Whey Culture With Propionibacterium freudenreichii ET-3 Is Effective on the Colitis Induced by 2,4,6-Trinitrobenzene Sulfonic Acid in Rats
- Cell-Cycle-Dependent Pharmacology of Methotrexate in HL-60
- FK614, a Novel Peroxisome Proliferator-Activated Receptor .GAMMA. Modulator, Induces Differential Transactivation Through a Unique Ligand-Specific Interaction With Transcriptional Coactivators
- Sclerosing Effect of OC-108, a Novel Agent for Hemorrhoids, Is Associated With Granulomatous Inflammation Induced by Aluminum
- Inhibitory Action of Daunorubicin on Lipopolysaccharide-Stimulated Inducible-Type Nitric Oxide Synthase Induction in Alveolar Macrophages
- Antinociceptive Effect of Shakuyakukanzoto, a Kampo Medicine, in Diabetic Mice
- Pharmacokinetic Interaction of Paeoniflorin and Sinomenine: Pharmacokinetic Parameters and Tissue Distribution Characteristics in Rats and Protein Binding Ability In Vitro
- Elucidating the Inhibitory Mechanisms of Magnolol on Rat Smooth Muscle Cell Proliferation
- The Protective Effect of H2-Receptor Activation Against the Duration of Myocardial Hypoxia/Reoxygenation-Induced Ventricular Fibrillation in Sensitized Guinea-Pig Hearts
- Activation of Spinal Anti-analgesic System Following Electroacupuncture Stimulation in Rats
- Facilitative Effect of a Glutamate Transporter Inhibitor (2S,3S)-3-{3-[4-(Trifluoromethyl)benzoylamino]benzyloxy}aspartate on the Expression of Methamphetamine-Induced Behavioral Sensitization in Rats
- Variable Neurotransmission Within Intrinsic Cardiac Ganglia
5
- QT PRODACT: A Multi-site Study of In Vitro Action Potential Assays on 21 Compounds in Isolated Guinea-Pig Papillary Muscles
- QT PRODACT: Inter- and Intra-facility Variability of the Action Potential Assay Using Isolated Guinea-Pig Papillary Muscles
- QT PRODACT: Evaluation of the Potential of Compounds to Cause QT Interval Prolongation by Action Potential Assays Using Guinea-Pig Papillary Muscles
- QT PRODACT: In Vivo QT Assay in the Conscious Dog for Assessing the Potential for QT Interval Prolongation by Human Pharmaceuticals
- QT PRODACT: In Vivo QT Assay in Anesthetized Dog for Detecting the Potential for QT Interval Prolongation by Human Pharmaceuticals
- QT PRODACT: In Vivo QT Assay With a Conscious Monkey for Assessment of the Potential for Drug-Induced QT Interval Prolongation
- QT PRODACT: Usability of Miniature Pigs in Safety Pharmacology Studies: Assessment for Drug-Induced QT Interval Prolongation
- QT PRODACT: Inter-facility Variability in Electrocardiographic and Hemodynamic Parameters in Conscious Dogs and Monkeys
- QT PRODACT: Sensitivity and Specificity of the Canine Telemetry Assay for Detecting Drug-Induced QT Interval Prolongation
- QT PRODACT: Comparison of Non-clinical Studies for Drug-Induced Delay in Ventricular Repolarization and Their Role in Safety Evaluation in Humans
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