|
List of Jounal Titles
A to Z index of Journal Title. Choose a letter.
Jpn J Pharmacol
85
- Isolation and Self-Renewal of Neural Stem Cells.
- Pharmacology and animal experimentation.
- Frontiers of human genome project and implications to pharmacology.
- Molecular mechanism of the death factor-induced apoptosis and its associated diseases.
- Current issues in clinical trials in Japan.
- Brain Drug Targeting Using Gene Technologies.
- A New Pharmacological Avenue to Antidepressants.
- Calcium regulation of striated muscle contraction and its genetic disorder.
- Studies on histamine with histidine decarboxylase as a probe: From purification to gene knockout.
- Mouse Models of Colon Cancer and Treatment.
- Functional alterations of astroglia on brain pathologies and their intracellular mechanisms.
- LOX-1, the endothelial oxidized LDL receptor: Identification and functional characterization.
- Functional analysis of calcineurin-mediated signalling pathway using fission yeast as a model system.
- Crystal structure analyses of membrane proteins; A case study for calcium pump from sarcoplasmic reticulum.
- Functional analysis of membrane proteins based on the tertiary structures.
- Activation of ATP-sensitive K+ channels by ADP and K+ channel openers; Homology model of Sulfonylurea receptor carboxyl-termini.
- Structures of transporters and drug design.
- Applications of Computer-Aided Drug Design Techniques to Studies of Transporters.
- PACAP-its present status and perspective.
- Regulation of pancreatic .BETA.-cell functions and glucose metabolism by PACAP.
- PACAP as an inhibitory neurotransmitter in gastrointestinal tract.
- PACAP as a regulatory factor in cardiovascular system.
- Generation of PACAP gene knockout mice and analysis of their brain functions.
- Genetic approaches to NF-.KAPPA.B signaling in innate immunity.
- Regulation of NF-.KAPPA.B pathway in response to several stresses in glial cells.
- Role of NF-.KAPPA.B in Rheumatic Disease.
- Possible role of a specific NF-.KAPPA.B inhibitor as anti-atherosclerosis agent.
- Gene Therapy of Glomerulosclerosis by Targeting NF-.KAPPA.B.
- Development of Microfabricated Histamine Biosensors.
- On-line analysis of histamine release from mast cels using a histamine sensor.
- Quantitative analysis of exocytosis visualized by video-microscopes in RBL-2H3 cells.
- Electrophysiological monitoring of mast cell functions.
- Allergen sensor.
- High Throughput Screening in the Japanese Pharmaceutical Industry.
- Feature of HTS and Assay Technologies.
- Pharmacological contribution to high throughput screening(HTS). Approach by low throughput screening.
- New approaches for high-throughput screening of drugs acting on ion channels.
- Reconstituted smooth muscle fibers as a tool for a tissue-based functional assay.
- Organ culture as a useful model for vascular proliferative disease.
- Prostaglandin E exerts a variety of actions via their receptors.
- Gastric Protection by Prostaglandin E: Relation to EP Receptor Subtypes.
- Pain, itch and EP receptors.
- A Significant Role of Prostaglandin E2-EP3 Receptor Signaling in Angiogenesis and Tumor Growth.
- Sickness behavior and EP receptors.
- Role of EP4 receptor in bone metabolism regulated by PGE.
- Development of selective compounds to four EP subtypes for prostanoid receptors and their expected clinical targets.
- The role of perivascular sympathetic nerve and regional differences in the features of sympathetic innervation.
- Direct observations of sympathetic cholinergic vasodilatation of in-vivo skeletal muscle small arteries.
- Purinergic modulation of vascular sympathetic neurotransmission.
- Presynaptic modulation of nitrergic neurogenic vasodilation in cerebral arteries.
- Regulation of vascular function by perivascular calcitonin gene-related peptide(CGRP)-containing nerves.
- Analyses of brain functions using GluR channel subunit knockout mice.
- Construction of transgenic mouse models for neurodegenerative deseases. Molecular mechanisms of neurodegeneration.
- RIKEN Mouse Full-Length cDNE Encyclopedia and its Application to Medical Research.
- A Large Scale Mouse ENU-Mutagenesis Project.
- Regulation of neural cell death and survival.
- Neuronal mechanism for death: Identification of the molecule that linksprotein aggregates to vacuolization and death.
- Self-renewal of Neural Stem Cells.
- A novel factor suppressing neuronal cell death by the wide spectrum of Alzheimer's disease genes.
- Brain Aging is a Multi-phase Process Characterized by Distinct Cellular and Molecular Mechanisms in Each Phase.
- Regulatory mechanism underlying Ca2+-induced Ca2+ release(CICR) in cardiac E-C coupling.
- Cardiac Na+-Ca2+ exchanger: Recent advances.
- Excitation-contraction properties of the mouse myocardium and their regulation.
- Regulation of cardiac Ca2+ signaling by cross talk of endothelin-1 and norepinephrine.
- Effects of Na+/H+ and Na+/Ca2+ exchange ingibitors on cardiac arrhythmias.
- Molecular Chaperones and its involvement in pathophysiology.
- Regulation of MHC class I antigen presentation by molecular chaperones and polyamines.
- A novel calnexin isoform for cystic fibrosis therapy.
- Chaperone inducers as a novel pharmacological approach for treatment of gastrointestinal and liver diseases.
- Function of heat shock proteins in the gluco-corticoid-mediated transcriptional regulation.
- Characterization of parchorin, a novel protein specifically expressed in water-secreting cells.
- Pharmacological modulation of transalveolar fluid absorption: New concepts in treatment of pulmonary edema.
- Aquaporin water channel in the eye: A promising ophthalmic drug target.
- Intracellular regulation of aquaporins: Insights from the analysis of hereditary nephrogenic diabetes insipidus.
- Role of NMDA receptor subunit and protein kinase C isoform in the development of morphine-induced rewarding effect.
- Drug dependence and cyclic AMP signal transduction cascade.
- Alterations in cerebral diazepam binding inhibitor(DBI) expression in drug dependence and its withdrawal.
- Neuroimaging approach to drug dependence-focused on chronic methamphetamine use.
- Drug Discovery in the 21st Century-Advantages and Disadvantages of Genome-based Research.
- Pharmacological evaluation of drug efficacy based on the mechanism of action.
- Mechanism-Based Evaluation of Drug Safety.
- Role of pharmacokinetic(PK) data for the evaluation of pharmacological effects of new drugs.
- An evaluation of non-clinical data from the point of view of a clinical pharmacologist.
- Asthma and atopic dermatitis: Models for genetic and genomic investigations of complex genetic diseases.
- Molecular classification by global gene expression profiling: Application on oncogenomic research.
- Functional genomic search of disease-related genes using microarrays with normalized rat cDNA library.
- Acute ischemic change of mRNA expression in the hippocampus by GeneChip array analysis: A starting point for post-genome strategy.
- Adrenomedullin in cardiovascular diseases.
- Adrenomedullin has multiple functions, binding the multitype receptors.
- Hemodynamic, Renal and Hormonal Effects of Adrenomedullin Infusion in Patients With Congestive Heart Failure.
- Pathophysiological assessment of adrenomedullin by mice gene engineering approach.
- Regulation of uterine contractility by adrenomedulin.
- Adrenomedullin in pregnancy.
- Mechanism of subtype-, stimulus- and cell-specific PKC translocation: A new target of drug.
- A cardioprotective agent, JIV519, attenuates post-ischemic myocardial injury through specific activation of .DELTA.-isoform of protein kinase C: Novel pharmacological effects that mimic ischemic preconditioning.
- Role of protein kinase C isozymes in interleukin 1 receptor signaling. With a special regard to expression of inducible nitric oxide synthase gene.
- Roles of protein kinase C isoforms in the development of vasospasm after subarachnoid hemorrhage.
- Interplay between protein kinase C isoforms and Rho/Rho kinase in the stretch-induced myosin light chain phosphorylation of canine cerebral artery.
- A role of protein kinase C isoform in insulin resistance.
- Chloride channels and transporters: Pharmacology and therapeutic application.
- Functional and molecular characteristics of the chloride channels in vascular smooth muscle.
- Regulation of chloride channel during the cell cycle.
- Regulations of Cl- channels by a scaffolding protein.
- Use of chloride blockers: A novel approach for cardioprotection against ischemia-reperfusion injury.
- Neural and Molecular Basis of Classical Eyeblink Conditioning.
- Appearance of clock-related genes-based circadian anticipation by timed feeding or injection of psychostimulant drug.
- Efficiency of hippocampal synaptic transmission during operant conditioning.
- The changes in synaptic efficacy in paralimbic structures accompanied with fear-related memories.
- Orexins and Orexin Receptors: From Reverse Pharmacology to Integrative Physiology.
- Hypocretin/Orexin and narcolepsy.
- Human dopamine receptor gene polymorphisms and their associations with clinical phenotypes.
- Paraneoplastic syndrome caused by mGluR1-blocking autoantibodies in Hodgkin's desease.
- TAK-779, a small molecule CCR5 antagonist with anti-HIV-1 activity.
- Molecular mechanism of leukocyte migration mediated by CCR2.
- The role of adrenergic receptors in the heart.
- Nociceptin receptor and its antagonists.
- Expression of exogenous opioid receptor as a target molecule for pain management. Concept for functional combination between drug and gene therapies.
- Analysis of Endocrine disrupting chemicals in food and biospecimen.
- Influence of the prenatal exprosed to bisphenol-A in the adaptation to the novel environment.
- The effect of fetal exposure to bisphenol A on the formation and maturation of the murine central nervous system.
- Effects of Bisphenol A on monoamine neurotransmitters.
- Effects of xenoestrogens on catecholamine synthesis, release and reuptake in cultured bovine adrenal medullary cells.
- Endocrine disruptors suppress peripheral nociception through metabotropic neurosteroid receptors.
- 13C-Breath tests.
- Urease: Diagnosis for Helicobacter pylori infection.
- Pancreatic enzymes.
- Hepatic phenylalanine hydroxylase activity.
- Pharmacological and clinical significance of cytochrome P450.
- Drug-food interaction concerning cytochrome P450(CYP) 3A4 and/or P-glycoprotein.
- Pharmacogenetic polymorphism and drug interactions.
- Clinical pharmacogenetics and its application to drug therapy.
- Hepatic cytochrome P450 isoenzymes and liver diseases.
- P-glycoprotein as blood-brain barrier and opioid-produced analgesia; Pharmacodynamic and pharmacokinetic studies.
- Effects of R-102444, an orally active 5-HT2 receptor antagonist, in rat models of peripheral arterial occlusive disease.
- The action of cyclosporin A, a P-glycoprotein inhibitor, on opioid-induced two central effects.
- Prevention of neurotoxicity of peripherally active drugs by efflux transporters at the blood-brain barrier.
- A New In Vitro Blood-Brain Barrier Model and Its Application for Transport Study.
- Peptide Drug Targeting Through the Blood-Brain Barrier.
- Genomic polymorphism of human organic anion transporter 1 gene.
- ABC transporters: Genetic diseases and its role in drug disposition.
- Polymorphism and neuropsychopharmacology of monoamine transporters.
- Genetic disorders caused by mutations of the heterodimeric amino acid transporter BAT1/rBAT.
- The polymorphism in the vitamin D-dependent calcium transport system in the small intestine.
- Isolation and distribution of endomorphins in the central nervous system.
- The antinociceptive properties of endomorphin-1 and endomorphin-2 in the mouse.
- Potentialities of mu-opioid receptor subtype by endomorphin-1 and -2.
- Molecular genetics of .MU. opioid receptor-gene mutant mice and analgesia, reward.
- The functional role of alternatively spliced .MU.-opioid receptor variants in the brain.
- Importance of genetic information for the improvement of individualized drug therapy.
- The contribution of basic pharmacology to drug information.
- Feedback of drug information to the society. A clinical pharmacologist's view.
- Drug information useful for avoiding side effects caused by drug-drug interactions.
- How to study the clinical trials for patient oriented in Japan.
- Pharmacology and advanced drug information.
- Mechanisms of ATP release from astrocytes.
- Ca2+ signalings evoked by ATP in cultured rat hippocampal astrocytes.
- ATP-induced chemotaxis of microglia.
- Mechanism of ATP-stimulated TNF-.ALPHA. release from rat microglia.
- ATP-induced IL-6 release from microglial cell line, MG-5.
- Itch and dermatitis. Clinical and therapeutic aspects.
- Human afferent C-fiber responses to itching induced by histamine.
- Evaluation for and mechanisms of itching in mice.
- Scratching behavior associated with allergic cutaneous reactions in mice.
- Identification of susceptibility genes for common bone and joint diseases.
- Molecular Mechanism of Vitamin D Actions.
- Role of bone-derived growth factors and their signaling pathways in bone metastasis.
- Signal Transduction in Osteoclasts.
- Signaling molecules in mechanical stress-induced osteogenesis.
- Modulation of bone metabolism related signaling by bone matrix proteins.
- A scientific point of view for the research on traditional Chino-Japanese and related herbal medicines.
- Present situation in the clinical assessment of the Kampo medicines.
- The development of natural medicine in the world.
- Assessment of Dihydro-honokiol and -magnolol as a Novel Type of Anxiolytic Agent.
- Behavioral Evaluation of the Anxiolytic-like and Side Effects of Dihydrogenated biphenyl compounds.
- Pharmacological characteristics of novel anti-depressive substance extracted from Perillae Herba.
- Ameliorative effect of paeoniflorin, a glycoside constituent of peony root, on spatial cognitive deficits and putative mechanisms of action.
- New direction of the effect of Kampo medicine: Molecular basis of the action of Bakumondo-to.
- Effects of constituent herbs and some ingredients of saiboku-to on histamine release from peritoneal mast cells in rats.
- The effects of Kampo medicines used for the climacteric disorders on CNS.
- Hepatoprotective Effect of Inchin-ko-to(ICKT).
- Cough and thromboxanes.
- On the mechanism of dry cough induced by an angiotensin-converting enzyme inhibitor.
- Antitussive mechanisms of .DELTA.-opioid receptor antagonist.
- The Rational Drug Design and Antitussive Effects of a Novel Opioid .DELTA.-Receptor Antagonist TRK-851.
- The action of antitussives in brain neuron level: Inhibition of 5-HT1A receptor activated.
- Role of pharmacological education for clinical trials. Present status and perspectives in Japan.
- The quality of Japanese clinical trials: Findings of GCP inspections.
- Current States and Issues of Japanese Clinical trials in view of the sponsor side.
- Current condition of clinical trials in Japan: From a physician's point of view.
- Pharmacogenetics and its clinical impact.
- Mechanisms of secretion of salivary proteins.
- Calcium dynamics and fluid secretion in salivary cells.
- Neuronal regulation of the function of membrane carrier protein in parotid glands.
- Expression of amino acid transporters in rat salivary glands.
- Functional analysis and transport system of antifungal protein in salivary glands.
- Role of the glutamatergic system in neuropathic pain.
- Characterization of the etiology of painful diabetic neuropathy and a therapeutic benefit of mexiletine and carbamazepine.
- Sciatic neualgia and prostanoids.
- Implications of brain-derived neurotrophic factor-mediated signaling pathway in thermal hyper-algesia induced by nerve injury in mice.
- Molecular mechanisms of neuropathic pain through Rho and Rho kinase.
- Summary of Cilostazol, a PDEIII Inhibitor.
- Cilostazol enhances nitric oxide production from the endothelium.
- Effect of cilostazol on local production of HGF(hepatocyte growth factor).
- Cilostazol suppresses intimal formation in dog grafted veins with reduction of angiotensin II-forming enzymes.
- Applications of hippocampal slice cultures to the analysis of excitotoxicity.
- Erythropoietin receptor mediated inhibition of exocytotic glutamate release and suppression of ischemic neuronal cell death in hippocampal slices.
- Regional difference of neuronal vulnerability in hippocampal slice cultures.
- Rat hippocampal organotypic culture as a potent tool for evaluation of parathyroid hormone neurotoxicity and its protective drugs.
- Circadian rhythm and clock genes.
- Biological rhythms and diseases.
- Pharmacokinetics of drugs and biological rhythm.
- Chronopharmacology of antibiotics.
- Chronopharmacological aspects of cardiovascular drugs.
- Chronopharmacology of antitumor drugs.
- Mechanisms of endothelium-dependent relaxation in carotid arteries from Watanabe heritable hyperlipidemic rabbits.
- Accelerated intimal hyperplasia with hyperglycemia and its modification by an aldose reductase inhibitor.
- Expression of inducible NO synthase by irradiation in vascular endothelial cells.
- Possible involvement of NF-.KAPPA.B in nitric oxide-induced inhibition of endothelin-1 production in cultured vascular endothelial cells.
- Involvement of endogenous NOS inhibitors in the impaired endothelium-dependent relaxation of pulmonary artery from the experimental SAH rabbit.
- Effects of hypergravity on endothelial functions.
- Chronic NO exposure downregulates EDHF-mediated relaxations in rat renal arteries.
- Comparison of the effects of endothelin ETA(J-112534) and ETA/ETB(J-104132) receptor antagonists on atherosclerosin in apolipoprotein E-defficient mice.
- Mechanisms underlying the reduced endothelium-dependent relaxation in human omental resistance artery in preeclampsia.
- Cyclic AMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells.
- Tissue kallikrein secretion from human endothelial cells.
- Stimulation of tetrahydrobiopterin synthesis by cyclosporine A in mouse brain microvascular endothelial cells.
- Hydrogen peroxide stimulates tetrahydro-biopterin synthesis in brain micerovascular endothelial cells.
- N.EPSILON.-(carboxymethyl)lysine-activated angiogenic potential of choroid suppressed angiogenesis of cultured retinal capillary in early stage of streptozotocin-diabetic rat.
- ATP released by hypotonic stimulation regulates cell volume via P2 purinergic receptor.
- Effect of ATP on angiogenesis induced by ischemia in mesenteric artery.
- The role of integrin .ALPHA.v.BETA.3 in PMN-induced angiogenesis.
- Regulation of PAR1 by trypsin in vascular endothelial cells.
- vascular Endothelial Growth Factor(VEGF) gene introduction as the promissing strategy in therapeutic postnatal neovascularization for ischemic tissue.
- Cytoprotective effects of Propofol on vascular endothelial cells.
- Endothelium-dependent hyperpolarization and relaxation are regulated by estrogen through the expression of gap-junctional protein connexin 43 in the rat mesenteric artery.
- Inhibitory effects of a specific chymase inhibitor in angiogenesis in hamster sponge granulomas.
- Alterations of Ca2+ mobilizing properties in migrating endothelial cells.
- Long-term effect of doxorubicin on endothelial function in organ cultured vascular tissue.
- Pharmacological characterization of tachykinin receptor mediating endothelium-dependent contraction and relaxation in rabbit intrapulmonary arteries.
- Effect of hydrogen peroxide on guinea pig nasal mucosa vasculature.
- Mechanisms of acetylcholine-induced vasorelaxation in high K+-stimulated rabbit renal arteries.
- Relation between ACh-induced relaxation and the Ca2+ responses in endothelial cells of rat aorta in situ.
- 15-deoxy-.DELTA.12,14-prostaglandin J2 inhibits endothelin-1 production in cultured vascular endothelial cells by inhibiting AP-1 activity.
- ATP-induced Ca2+ responses of mouse aortic endothelial cells using a multi-photon excitation fluorescence microscopic system.
- Local regulation of rear retractions by flow-induced Ca2+ transients in endothelial cells.
- On the mechanisms of activation of a non-selective cation channel by sphingosine-1-phosphate in human endothelial cells.
- Regulation via protein kinase G in fluid flow-induced ca2+ influx enhanced by lysophosphatidic acid in cultured endothelial cells.
- Differential involvement of endothelium-derived cyclooxygenase products in stretch- and ACh-induced contractions of rabbit pulmonary artery.
- The role of kinases for the endothelin-1-induced vasoconstriction.
- Effects of nucleotides on volume-regulated anion channel current.
- Further pharmacological characterization of nicotine-induced endothelium-dependent contraction in rat basilar artery.
- The interaction between components of the fibrinolytic system and GPIb/V/IX of platelets thrombus formation in mice.
- Temperature-dependent change in vascular endothelial function of the golden hamster during hibernation.
- Short term hypercholesterolemia enhances endothelium-derived hyperpolarizing factor-mediated relaxation to acetylcholine in rabbit renal artery.
- Biological effects of fullerence C60 derivatives: Inhibition of endothelium-derived relaxation in rabbit thoracic aorta.
- Pharmacological approaches for calcium mobilization by vitisin C, a novel plant oligostilbene from Vitis coignetiae in the endothelial cells from rat aorta.
- Effects of KB-R 7943 on ischemia/reperfusion arrhythmias in dogs.
- Contribution of .BETA.-adrenergic activity to the QTc prolongation induced by a selective Iks blocker L-768,673.
- Torsadegenic action of an antipsychotic drug sulpiride assessed by the canine chronic AV block model.
- Drug-induced ventricular arrhythmia in rabbit isoalted hearts with atrioventricular block.
- Effect of NIP-142, a novel anti-arrythmic agent on mouse cardiac action potential.
- Atrial selective prolongation by NIP-142 of refractory period and action potential duration in guinea-pig myocardium.
- Suppressive effect to AV nodal conduction of Ikr blocker Nifekalant in rat.
- Strategy for preclinical evaluation of the proarrhythmic risk.
- Expression of p22-phox and gp91-phox, essential components of NADPH oxidase, increases in infarcted sites of the left ventricle after myocardial infarction.
- Effects of quinapril on rats with chronic heart failure.
- Lithospermic acid B in Danshen water-extract improves angiotensin II-induced hyperplastic response in neonatal rat cardiac nonmyocytes.
- Suppression of cardiac chymase-dependent angiotensin II-generation after myocardial infarction in hamsters.
- Effects of chronic treatment with J-104132, a potent ETA/ETB antagonist, on heart failure in salt-loaded dahl salt-sensitive rats.
- Protective role of G.BETA..GAMMA. released from Gq.ALPHA. in .ALPHA.1-adrenergic receptor induced apoptosis in rat neonatal cardiomyocytes.
- Whole body hyperthermia induces expression of heat shock proteins and suppresses ischemic ventricular arrhythmias in rat heart.
- Role of Angiotensin converting enzyme(ACE) in Adriamycin-induced cardiomyopathy in hamster.
- Neutral endopeptidase inhibition enhances endogenous ANP-induced suppression of collagen synthesis in cultured cardiac fibroblasts.
- Alterations in .BETA.-adrenergic signal transduction of cardiomyocytes in rats with chronic heart failure.
- Protective effects of serotonin derivatives isolated from safflower against postischemic myocardial dysfunction.
- Cardioprotective effect of NPY-Y1 antagonist on global ischemia of rat isolated heart.
- Protective effects of sarpogrelate, a 5-HT2A antagonist, against postischemic myocardial dysfunction in guinea-pig hearts.
- Chronic therapy with trandolapril is associated with reduced expression of interleukin-1.BETA. protein in failing rat hearts.
- Endothelin-1 increases the LV inner layer flow rate in underperfused non- and diabetic rat hearts.
- Influences of antimalarial drugs on the acetyl-choline-receptor-operated potassium current in isolated guinea-pig atrial myocytes.
- Effect of a Na+/H+ exchange inhibitor SM-20550 on mitochondrial respiration in ischemic reperfused rat hearts.
- In vitro and in vivo pharmacology of a new Na-H exchange inhibitor, T-162559.
- Inhibitory effect of the HMG-CoA inhibitor, fluvastatin, on lysophosphatidylcholine induced non-selective cation current in guinea-pig ventricular myocytes.
- Physical association between the cytoplasmic domains of the Ca2+-ATPase of cardiac sarcoplasmic reticulum and phospholamban.
- Efffects of T-162559, a new Na-H exchange inhibitor, on myocardial infarct size and release of cardiac proteins in coronary artery occlusion -reperfusion dogs.
- Influlence of diabetes on the expression of cardiac K+ channels which are essential components of the transient outward current.
- Potent and long-lasting cardioprotective effects of T-162559, a new Na-H exchange inhibitor, in rats.
- Cardiac effects of Kampo extracts assessed in the canine isolated, blood-perfused heart preparations.
- Intracellular free calucium dynamics of cultured neonatal rat cardiocytes exposed to mechanical strech.
- Mechanical stretch stimulates taurine uptake and transport gene expression in cultured neonatal rat cardiomyocytes.
- Diabetes-induced alterations in protein and gene expression of the cardiac sarcoplasmic reticulum protein, phospholamban, and its phosphorylation.
- Ultrastructure of sarcolemma in cardiomyopathic(CM) hamsetr hearts.
- Physiological functional analyses of troponin T mutations that cause familial hypertrophic cardiomyopathy.
- Histamine H2-receptor mRNA expression in myocardial tissues of mammalian species including humans.
- Expression of green fluorescent proteins and cameleons in cultured hepatocytes and cardiomyocytes using improved adenoviral expression vectors.
- Analysis of roles of prostaglandin I2 and thromboxane A2 in cardiac ischemia/reperfusion injury using mice lacking each of their respective receptors.
- Improvement of ischemic/reperfusion injury by diazoxide is attributed to preservation of mitochondrial function during ischemia.
- Antiarrhythmic effects of FR 168888, a new Na+/H+ exchange inhibitor, on reperfusion ventricular arrhythmias in rat.
- Cardioprotection against ischemia-reperfusion injury by PAK-200, a dihydropyridine analogue with inhibitory effect on Cl- but not Ca2+ current.
- Nicorandil metabolism in rat myocardial mitochondria.
- Effect of sodium nitroprusside on rested state contraction of guinea-pig papillary muscle.
- Dual inotropic responses to endotheline-1 in the presence of high or low concentrations of norepinephrine involve differential regulation of Ca2+ signaling in aequorin-loaded canine right ventricular myocardium.
- Effect of mutations in human cardiac troponin T on the calcium-sensitive ATPase activity of myofibrils and actomyosin preparations.
- Mitoxantrone enhances Ca2+ release from the sarcoplasmic reticulum in isolated guinea pig hearts.
- Effects of mutations in troponin I found in familial hypertrophic cardiomyopathy on troponin C I-interaction.
- Increased susceptibility to myocardial ischemia/reperfusion injury in mice lacking the prostanoid EP3 and EP4 receptors.
- Cardioprotective effects of Okinawan medicinal herbs against ischemia-reperfusion injury in isolated perfused rat hearts.
- Stimulation of peroxisome proliferator-activated receptor-.ALPHA.(PPAR-.ALPHA.) decreases cardiac hypertrophy and endothelin-1 expression in rats both in vitro and in vivo.
- Dual effects of endothelin-1 on the twitch contraction of mouse right ventricle.
- Regulation of Ca2+ signaling induced by endothelin-1 in indo-1 loaded canine ventricular myocytes.
- Inhibitory effect of adrenomedullin on neurotransmission of calcitonin gene-related peptide(CGRP)-containing vasodilator nerves in the rat mesenteric resistance artery.
- 17 .BETA.-Estradiol regulates .BETA.-adrenoceptor-mediated vasorelaxation through cytochrome P450 system in female rat aorta.
- 17.BETA.-Estradiol attenuates isoprenaline-mediated vasorelaxation in male rats.
- Effect of neuropeptide Y on the contraction of various rat isolated blood vessels.
- Changes in density of calcitonin gene-related peptide(CGRP)-containing vasodilator nerve(CGRP nerves) fibers in SHR mesenteric artery and effect of long-term treatment with antihypertensive drugs.
- Altered cyclic AMP-mediated vasorelaxation in chronic hypoxia-induced pulmonary hypertensive rat.
- Effects of SK&F 96365 and LOE 908 on the mechanical responses to noradrenaline and thapsigargin in guinea-pig aorta.
- Endothelin-1-induced oscillatory chloride currents in smooth muscle cells of rat intact microvessels.
- Endothelin/endothelin receptor type A mediates closure of rat ductus arteriosus at birth.
- Decrease in phenylephrine-induced contraction in isolated thoracic aortae from SART(repeatedly cold)-stressed rats.
- Role of endothelin ETB receptor in neointima formation after balloon injury.
- Vascular proliferation induced by PDGF and vasocontractile peptides assessed by organ culture system.
- Effects of various receptor agonists on intracellular Ca2+ concentration in cultured vascular smooth muscle cells.
- Vascular responsiveness in mesenteric arteries of OLETF(Otsuka Long-Evans Tokushima Fatty) rats.
- Relaxant effects of several class I antiarrhythmic drugs on the isolated pig coronary artery smooth muscle.
- The difference in relaxant property exists between two phosphodiesterase type 5 inhibitors, sildenafil and T-1032, in the isolated rat aorta.
- Existence of .ALPHA.-adrenoceptor subtypes on isolated an perfused canine mandibular alveolar arteries.
- Intracellular localiation of histamine in the cultured smooth muscle cells from porcine coronary artery.
- Histamine potentiates the PDGF-induced proliferation of cultured smooth muscle cells from porcine coronary artery.
- A direct vasodilator effect of urocorutin on rat aortic smooth muscle.
- Effective inhibition of Na+-dependent elevation of intracellular Ca2+ concentration by KB-R7943 in rat carotid arterial cells.
- HNS-32, a novel azulene-1-carboxamidine derivative, inhibits nifedipine-sensitive and -insensitive contractions of the isolated rabbit aorta.
- Protein kinase C .DELTA. and .ALPHA. are involved in the development of cerebral vasospasm after subarachnoid hemorrhage.
- The expression of L type of voltage-operated Ca2+ channels(L-VOC) is down-regulated by MAP kinase pathway in the proliferating smooth muscle cells.
- A guanylyl cyclase inhibitor, ODQ, is a potent K+ channel blocker, also.
- Midkine accelerates Platelet Derived Growth Factor-induced migration of mouse vascular smooth muscle cell.
- Effect of Y27362 on the contraction in the bovine middle cerebral artery.
- Intracellular alkalinization activated a SKF96365-sensitive Ca2+ influx.
- Rho-kinase is involved in Ca2+ sensitization of vascular smooth muscle following protein kinase C activation.
- Contribution of sarcoplasmic reticulum(SR) Ca2+ to the activation of Ca2+-activated K+(KCa) channels in the resting state of arteries from spontaneously hypertensive rats(SHR).
- Ca2+ buffering functions of sarcoplasmic reticulum(SR) in the small mesenteric artery from spontaneously hypertensive rats(SHR).
- Mechanisms underlying bradykinin-induced vasoconstriction in rat mesenteric resistance arteries.
- Decreased contractile response of the aorta from fructose-induced hypertensive rats.
- Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells.
- Inhibitory Effects of Chloride Channel blockers on Acidic pH-induced Contraction in Rat Aorta.
- Effects of vasopressin on contraction in isolated rat basilar artery.
- Influence of blockade of CD11b by monoclonal antibody on neointimal formation in carotid artery of vitamin E deprived mice.
- Nitric oxide inhibits the expression of transcription factor ETS-1 and cell migration in rat aortic smooth muscle cells.
- Involvement of protein kinases in K'+'-induced contraction of rat caudal arterial smooth muscle.
- 15-deoxy-.DELTA.12,14-prostaglandin J2 induces re-differentiation of cultured human vascular smooth muscle cells.
- Heme oxygenase-1 gene induction as novel potential anti-cerebral vasospasm drug target.
- Lysophosphatidylcholine increases protein tyrosine phosphorylation and enhances vascular K+-induced contraction in the rat aorta.
- Effect of 5-HT on inducible NO synthase(iNOS) and cyclooxygenase-2(COX-2) induction in vascular smooth muscle cells from normotensive and genetically hypertensive rats.
- Positron emission tomography study on neuroprotective effect of TRA-418, an anti-platelet agent in a monkey model of stroke.
- Measurement of blood pressure and postnatal maturation of baroreflex regulation in newborn mice.
- Effect of cigarette smoke on cardiovascular function in spontaneously hypertensive rats.
- Contribution of endothelin-1 to progression of right-sided heart failure caused by pulmonary hypertension in rats.
- Nitric oxide metabolite(NOx) concentrations in serum of hypertensive patients at rest, and its meaning.
- Roles of endogenous NOS inhibitors and endothelin-1 in monocrotaline-induced pulmonary hypertensive rats.
- Cholinergic stimulation-induced pressor responses in the lateral septal area are mediated via central angiotensin receptors in rats.
- Central angiotensin receptor blockade inhibits pressor responses induced by forced immobilization in rats.
- Gene expression of kallikrein, kininogen and bradykinin receptor in the heart in mouse model of two-kidney one-clip hypertension.
- Effects of caffeine on resting membrane potential and action potential of esophageal striated muscle of rats. Comparison between preparations from normotensive and hypertensive rats.
- Spectral Power Measurements of Heart Rate and Systolic Blood Pressure Variability Suggest Biphasic Changes in Autonomic Activity with Hypertension Process and Age in Conscious Rats.
- Pharmacological properties of R-102444, a novel 5-HT2 receptor antagonist.
- Comparison of the contribution of NO and endothelium-derived hyperpolarizing factor(EDHF) to the depressor responses to platelet activating factor(PAF) in rats.
- Increased plasma PAI-1 concentration and accelerated neointimal formation following endothelial injury in hypercholesterolemic mice lacking ACAT-1.
- Reduction of Heparin-Induced Hemorrhage and Enhancement of Neuroprotection by Free Radical Scavenger in the Rabbit MCA Occlusion Model.
- Effects of cetirizine and astemizole on the ventricular activation, the effective refractory period and RT intervals in dogs hearts with myocardial infarction.
- Effect of docosahexaenoic acid on the urinary excretion of catecholamine in stroke-prone spontaneously hypertensive rats.
- Activation of neuronal NO synthase via glutamate receptors is involved in DOPA-induced depressor responses in the nucleus tractus solitarii of rats.
- Augmented contractile responses to phenylephrine of retinal arterioles in the streptozotosin-induced diabetic rat.
- Effect of long-term treatment with antihypertensive drugs on levels of Calcitonin Gene-Related Peptide(CGRP) mRNA in the Spontaneously Hypertensive Rat(SHR).
- Perindopril improves the mortality of stroke-prone hypertensive rats without hypotension.
- Possible Involvement of Nitric Oxide on Cyclosporine-induced Hypertension of Rats.
- An anti-diabetic compound FPFS-410 exerts anti-hyperlipidemic effects with LPL enhancing activity.
- Effect of Anti-platelet Drug on Mouse Whole Blood Aggregation by A Novel Whole Blood Aggregometer with Screen Filtration Pressure Method.
- Estimation of Anti-platelet Drugs on Platelet Aggregation with a Novel Whole Blood Aggregometer by a Screen Filtration Pressure Method.
- Nitrotyrosine content in LDL modified with aqueous extracts of cigarette smoke.
- Estimation of anti-platelet aggregation effects with screen filtration method and turbidimetric method.
- Stretch activates MAP kinases via angiotensin and endothelin systems in vascular smooth muscle cells.
- T-1032, a specific phosphodiesterase type 5 inhibitor, improves the survival rate in cardiomyopathic hamsters with heart failure.
- Effect of long-term combined treatment with FR172357, non-peptide bradykinin B2 receptor antagonist, and temocapril on periarterial nerve function in SHR.
- Effects of Y-39241, a new 5-HT2 antagonist, on peripheral obstructive disease models.
- Antiarrhythmic effects of SMP-300, a new Na+-H+ exchange inhibitor, on canine ventricular arrhythmias.
- Effect of insulin on vascular responses to spinal cord stimulation and vasoactive agents in pithed rats.
- Organ-protecting and life span-prolonging action of pranidipine in stroke-prone spontaneously hypertensive rats(SHR-SP).
- Effect of a chymase inhibitor in a hamster sponge implant model.
- Effects of captopril and thiorphan on bradykinin-induced biphasic response in isolated porcine basilar artery.
- Effect of 2-aminoethane sulfonic acid(Taurine) on lipid metabolism in hyperlipidemic syrian hamsters.
- Inhibitory effect of KT3-671 on angiotensin II-enhanced oxidized LDL uptake in macrophages.
- Effects of long term hesperidin and .ALPHA.-glucosyl-hesperidin administration to spontaneously hypertensive rats.
- Modulation by protease-activated receptors of gastrointestinal transit: Roles of apamin-sensitive potassium channels and L-type calcium channels.
- Inhibition of both COX-1 and COX-2 is required for NSAID-induced small intestinal ulceration in rats.
- Lack of Small Intestinal Ulcerogenecity of Nitric Oxide-Releasing Indomethacin(NCX-530) in rats.
- Failure of Parenteral Aspirin to Induce Damage in Rat Stomachs: Protective Action of Salicylic Acid.
- Evidence that endogenous nitric oxide inhibits substance P-ergic transmission in the hamster ileum.
- Interplay of nitrergic and peptidergic neurons in the hamster jejunum.
- Z-338 enhances acetylcholine release from the canine stomach by blocking muscarinic autoreceptors in vivo microdalysis.
- Effect of TAK-637 on the viscerosensory response caused by colorectal distension in rabbits.
- The effects of diphenidol on drug-induced emesis in the dog and ferret.
- Participation of reactive oxygen species in serotonin(5-HT) production of guinea-pig colonic mucosa.
- Tolerance to inhibitory action of ethanol on gallbladder contraction.
- Improved effect of Dai-kenchu-to on accelerated small intestinal movement.
- Roles of NF-.KAPPA.B activation and apoptosis on ischemia-reperfusion injury in the rat liver.
- Stimulatory effect of centrally injected dynorphin and nociceptin on gastric acid secretion in anesthetized rats.
- Effects of tropisetron, a 5-HT3 receptor antagonist, on delayed emesis induced by cisplatin in ferrets.
- Pharmacological properties of KF66854, a novel 5-HT4 receptor agnonist with quinazoline structure, in vitro.
- The effects of resiniferatoxin, an ultrapotent capsaicin analogue, on cisplatin- and apomorphine-induced emesis in the dog.
- Protease-activated receptor-2(PAR-2) in gastric mucosa: Distribution and modulation of acid output.
- Ulcerogenic influence of COX-2 inhibitors in the stomach of adjuvant-induced arthritic rats.
- Ghrelin stimulates gastric acid secretion and motility in rats.
- Gastroprotective action y Meiji Bulgaria Yogurt LB81 Plain against gastric lesions induced by HCl or EtOH in rats.
- Dietary iron overload accelerates progression in pig serum-induced liver fibrosis in rats.
- Adaptive cytoprotection by capsaicin is enhanced by sensitization of CGRP-containing sensory nerve by prostaglandin I.
- Evaluation of physiological significance of calcitonin gene-related peptide(CGRP) in gastric mucosa with water immersion and restraint stress(WRS)-induced gastric lesion model in rats. (II).
- The herbal medicine Dai-kenchu-to and its active component [6]-shogaol increase intestinal blood flow in rats.
- Bicarbonate Stimulatory Action of Nizatidine, A Histamine H2-Antagonist, in Rat Duodenums.
- Inhibition of concanavalin A-induced mice hepatitis by coumarin derivatives.
- PGE, receptor EP4 subtype in mucosal defense in dextran sodium sulfate-induced colitis of the mouse.
- Healing acceleration of Egualene sodium(Egualene) on H. pylori-infected acetic acid ulcer rats.
- Involvement of kallikrein-kinin system in development of experimental ulcerative colitis induced by dextran sulfate sodium in rats.
- Pathogenesis of histamine-induced gastric lesions in gastric artery-ligated rats.
- Hypertrophic gastropathy, resembling Menetrier's disease, in histamine H2 receptor-deficient mice.
- Histamine level in the rat portal vein blood: A study using microdialisis probe.
- Specific expression of small conductance Ca2+-activated K+ channel, SK3 in the interstitial cell of Cajal of rat gastrointestinal tract.
- 5-HT-induced extra-cellular potential changes mediated by 5-HT3, 5-HT4 and 5-HT1A receptors on isolated rat abdominal vagus nerve.
- Relationship between colonic motility and defecation in conscious guinea-pigs.
- Mechanism underlying orexin-induced contraction of guinea pig intestine.
- Involvement of intrinsic nerves in modulating neuromuscular transmission evoked by vagus nerve stimulation in the striated muscle esophagus of the golden hamster.
- Z-338 potentially antagonizes muscarinic M1 and M2 receptors expressed in Xenopus oocytes.
- Apamin, a selective SK channel blocker, enhances lower-gastrointestinal motility and transit in rats.
- Effect of TAK-637, a neurokinin-1(NK1) receptor antagonist, on stress-induced defecation in Mongolian gerbils.
- Increase in calcium influx by stannous chloride in MC3T3-E1 osteoblastic cells.
- Adrenergic stimulation of osteoclastogenesis mediated by osteoclast differentiation factor in bone marrow cells.
- The effects of bisphosphonates on tyrosine phosphatase activity of osteoblastic cell line, MC3T3-E1.
- In vivo stimulation of sympathetic nervous system modulate osteoblastic activity.
- Tooth and cranio-facial development in cathepsin K-deficient mice.
- A cyclic peptide inhibitor of the TNF-TNF receptor interaction can inhibit osteoclastogenesis by interrupting the RANKL-RANK interaction.
- Effect of phenytoin alone and in combination with alfacalcidol on the tibial metaphysis in growing rats.
- Signaling cascades which control the branching morphogenesis of fetal mouse submandibular gland.
- Evidence that an intracellular osteopontin associated with the CD44 is required for the cell fusion in osteoclasts.
- Comparison of the levels of vitamin K analogues in osteoporotic or osteoarthritis patient bone.
- Cbfa1 independent Osteogenic Action of Statins in MC3T3-E1.
- Molecular events caused by cyclic stretch in spinal ligament cells from patients with ossification of posterior longitudinal ligaments.
- Cyclic AMP stimulates the differentiation and mineralization of bone cells via ERK activation, as PTH does.
- Signal transduction pathway of calcitonin-receptor-ERK in bone forming cells.
- Inorganic phosphate drives nuclear export(not import) of Runx2/Cbfa1 and then induces Cbfa1-independent ossification of chondrocytic clone ATDC5.
- Changes in the concentrations of vitamin K analogues in bone after long-term administration of zonisamide, an antiepileptic agent, in growing rats.
- Effect of Menatetorenone(K2) on bone mineral density and bone atrength in Ca/Mg deficient rats.
- Evaluation of mouse scratching behavior using a new apparatus, MicroAct.
- Circadian changes of serum corticosterone, cytokine and locomotor activities in NC/Nga mice.
- Studies on immunosuppressive effects of auranofin.
- Effect of prednisolone ointment on perturbation in permeability barrier induced by irritant contact dermatitis.
- New allergic rhinitis model using local sensitized rat.
- Pharmacological Effects of Steroidal Medicines for External Application on Atopic Dermatitis Challenged with Picryl Chloride in NC/Nga Mice.
- Studies of experimental allergic dermatitis involving repeated active-sensitization and challenge in mice. (II).
- Effects of a cytokine suppressive agent, FR167653, on the early and late phases of the rat carrageenin-induced pleurisy.
- Suppression of ear swelling by NOS inhibitor in a contact dermatitis model of mice.
- Effect of heat exposure on activation of vascular permeability by lipopolysaccharide in mice.
- Different in vivo and in vitro effects of lipopolysaccharide(LPS) and lipoteichoic acid(LTA) on mouse tumor necrosis factor-alpha(TNF) release.
- LOX-1(lectin-like oxidized LDL receptor-1) is a proinflammatory componant of endotoxin shock.
- The lack of mucosal mast cells contribution to rat tracheal contraction: Functional heterogeneity of mast cells.
- Inhibitory effects of 2-aminoethoxydiphenyl borate(2APB) on store-operated calcium entry and degranulation in rat basophilic leukemia(RBL-2H3) cells.
- The role of mast cells in airway remodeling induced by repeated antigen challenge in mice.
- Novel cytoprotective action of calcitonin generelated peptide on ischemia/reperfusion injury of rat liver.
- Novel endogenous anti-inflammatory pathway mediated by PPAR .GAMMA. in intestinal ischemia-reperfusion injury.
- Clinicopathological and immunological studies on Nigella sativa oil in case of experimental STZ-induced diabetes mellitus in hamster.
- Studies on itching in toluene-2,4-diisocyanate(TDI)-induced experimental allergic dermatitis. VI. Development of an itching model induced by low concentrations of TDI in hairless mice.
- Studies on itching in toluence-2,4-diisocyanate(TDI)-induced experimental allergic dermatitis. VII. Development of an itching model in dry skin-hairless mice.
- Study of experimental late type rhinitis in guinea pigs and effect of Hyaluronic acid poly sulfated ester.
- Effects of acetaminophen on immune responses in mice. (II).
- Involvement of prostaglandin receptors IP and EP3 in the ednotoxin-induced enhancement of writhing responses.
- Effect of Hyaluronic acid poly sulfated ester on experimental allergic rhinitis in guinea pigs.
- Screening of novel potent IV .ALPHA.-cytosolic phospholipase A2 inhibitors and antiinflammatory activities.
- Involvement of an inducible prostaglandin E synthase in the exudation of rat carrgeenin-induced pleurisy.
- Selective prostaglandin biosynthesis inhibition of zaltoprofen in the inflammatory site.
- Effects of naturally occurring isoflavones on prostaglandin E2 production.
- Potential role of phosphodiesterase 7 in human T cell function: Comparative effects of two phosphodiesterase inhibitors.
- Modulation of muscarinic receptor gene expression in human mononuclear leukocytes(MNLs) stimulated by Staphylococcus aureus Cowan I strain(SAC), a B-cell activator.
- Expression of an inducible prostaglandin E synthase of rats in the LPS-stimulated macrophages and the exudate of the zymosan-induced pleurisy.
- Reduction of acetylcholine release by apelin, a novel immunologically active endogenous peptide, in MOLT-3 cells, a human leukemic T-cell line.
- A specific up-regulation of M5 muscarinic acetylcholine receptor (mAChR) subtype gene expression by phytohemagglutinin (PHA), a T-cell activator, in CEM cells, a human leukemic T-cell line.
- Reduction of intracellular acetylcholine content and release by ONO-DI-004, a novel EP1 receptor agonist, in MOLT-3 cells, a human leukemic T-cell line.
- A transient increase of intracellular free calcium ion concentration and up-regulation of .ALPHA. 7 nicotinic acetylcholine receptor subunit gene expression by nicotine in CEM, a human leukemic T-cell line.
- The modulatory action of histamine on the LPS-induced metallothionein-I mRNA expression in the mouse spleen via H2 receptors.
- Studies on itching in toluene-2,4-diisocyanate(TDI)-induced experimental allergic dermatitis. V. Effect of an antihistaminic on increase of scratching and biting behavior in guinea pigs.
- The Effect of Olopatadine hydrochloride, an Antiallergic Drug, on Experimental Ocular Allergic Reaction in Rats.
- Histamine is a potent inducer of IL-18 and IFN-.GAMMA. in human peripheral blood mononuclear cells.
- Role of histamine H3 receptor on peripheral tissue.
- Inhibitory effects of glucocorticoids on rat eosinophils in vitro.
- Mechanisms for histamine-induced VEGF production in the granulation tissue in rats.
- Cell proliferation and soluble mediators induced by IL-1.BETA. in human synovial fibroblasts.
- Cyclooxygenase-2 overexpression stimulates amyloid .BETA.-protein production in neuronal cells.
- Host kallikrein-kinin system facilitates angiogenesis and tumor growth.
- The effects of thiazolidinedione on the human basophilic leukemia cell line KU812, which is independent of peroxisome proliferator-activated receptor .GAMMA..
- Effects of indomethacin on the hypothermia in a parasitic nematode infection.
- Separation and purification of the endogenous substances inhibiting passive cutaneous anaphylaxis in the rat.
- Possible participation of intracellular platelet-activating factor in NF-.KAPPA.B activation in thapsigargin-stimulated rat peritoneal macrophages.
- Effect of aging on chronopharmacokinetics of aminoglycosides in rats.
- Study of polyamine level in various tissues of etoposide-treated rats.
- Study on the emetic response in pigeons (15): Antiemetic effect of dexamethasone on cisplatin-induced dual emesis.
- Tri-n-butyltin at environmentally-relevant concentrations facilitates synaptic transmission in rat brain neurons.
- The effects of methylazoxymethanol on the rat embryo using a whole embryo culture method.
- Reproductive Immunotoxicity of di-2-ethyl-hexylphthalate(DEHP) in Mice.
- Long-term intake of rapeseed oil as the sole dietary fat and altered membrane function in stroke prone spontaneously hypertensive rats.
- Estimation of in vivo toxicity of theophylline and its relation to drug level in plasma.
- Black tea extract, thearubigin fraction, counteracts the effect of tetanus toxin in mice.
- Effect of tri-n-butyltin on NMDA-induced currents in rat CNS neurons.
- Determination of QT prolongation induced by various drugs with microelectrode technique.
- Inhibitory effects of organotin compounds on voltage-dependent, tetrodotoxin-insensitive Na channel current in guinea-pig dorsal root ganglion cells.
- Effect of diphenhydramine on QT-interval in freely moving rats.
- Biodegradation of 2,3,7,8-tetrachlorodibenzo-p-dioxin(TCDD) in rat liver microsomes.
- The increase of Cd-induced hepatotoxicity by estrogenic endocrine disruptors, bisphenol A and its relation with the decrease of hepatic metallothionein synthesis.
- Flow Cytometric Estimation on Cytotoxic Activity of Leaf Extracts from Seashore Plants in Subtropical Japan.
- Cardiac toxicity of diesel exhaust particles(DEP).
- Influence of TCDD on endochondral ossification.
- The role of adrenomedullin in the regulation of bovine pupillary size.
- Pharmacodynamics of animals in the approval and licence of prescription drugs in Japan.
- Small molecular weight heat shock-related protein, HSP20, exhibits an anti-platelet activity by inhibiting receptor-mediated calcium influx.
- Adrenomedullin suppresses platelet-derived growth factor- or extracellular ATP-induced cell proliferation through activation of protein kinase A in human oligodendroglial KG-1C cells.
- Adrenomedullin receptors in rat choroid plexus.
- Differential contribution of protein kinase C isoforms of to insulin secretion in rat pancreatic .BETA.-cells.
- Phenotypic change of adrenomedullin receptor components in cultured rat vascular smooth muscle cells.
- Mechanism underlying the vasorelaxation induced by hydrogen peroxide in rabbit.
- Biological activities and chromatographic separations of the venom from the redfin velvetfish.
- Effect of long-term administration of Ninjin-yoei-to on free radical, lipid peroxidation and life-span in aged rats.
- Influences of the 5-HT2 receptor antagonist on effects of selective serotonin and noradrenaline reupkae inhibitors in forced swimming test.
- Involvement of 5-HT receptors in the tricyclic antidepressant clomipramine-induced hyperglycemia in mice.
- Involvement of dopamine in the 5-HT releasing drug p-chloroampehetamine(PCA)-induced hyperthermia in mice.
- Involvement of nitric oxide(NO) in hyperleptinemia induced by 5-hydroxytryptophan(5-HTP).
- Real time monitering of histamine release from mast cells using histamine microsensor.
- Angiotensin II and endothelin-1 contribute to the development of gingival overgrowth induced by phenytoin or nifedipine.
- Regulations of cytosolic Ca2+ concentration and insulin secretion by nitric oxide in rat pancreatic.
- Sodium nitroprusside protects RA W264 cells against nitric oxide-induced cell death.
- Isolation, sequence analysis and function of cDNAs endocoding ion channel blocking peptides from Honduran yellow-brown scorpion Centruroides margaritatus.
- Effect of anandamide on substance P release from cultured rat DRG cells.
- The endothelium-dependent vasodilator response of human urotensin II on the rat coronary circulation.
- Effects of a serotonin precursor 5-hydroxytryptophan(5-HTP) on serum leptin levels and expression of leptin mRNA in the white adipose tissue of mice.
- Upregulation of ACE-dependent and chymase-independent angiotensin system in canine cardiac sympathetic ganglia.
- Role of K+ channels in the PACAP-induced adrenal catecholamine secretion.
- Mechanism of prostaglandin D2-stimulated heat shock protein 27 induction in osteoblasts.
- Influence of aging on the prostacyclin synthesis in the rat heart.
- Dexamethazone inhibits catecholamine secretion from the isolated perfused rat adrenal gland.
- Effects of tetrahydrobiopterin on arachidonic acid metabolism in platelets and low density lipoprotein oxidation.
- Nitric oxide has differential modulatory functions in the activities of cyclooxygenase-1 and -2.
- .ALPHA.2-Adrenoceptor antagonistic property of OPC-28326, a selective hindlimb vasodilator.
- State-dependent inhibition of L-type Ca2+-channels in A7r5 cells by structurally-related dihydropyridine derivatives.
- The structure and orientation of domain IV S6 of sodium channel.
- The functional role of motif YIPP with the intracellular carboxyl tail in angiotensin II-binding of human AT1 receptor.
- Binding and functional affinity of ketanserin, sarpogrelate and M-1 in human recombinant alpha-1 adrenoceptor subtypes.
- A direct measurement of the liquid junction potential between a 3M KCl electrode and a physiological solution.
- Evaluation of the functional role of muscarinic K+ channels in the parasympathetic regulation of the sinus rhythm.
- Analysis of the negative chronotropic action of efonidipine in rabbit sinoatrial node cells.
- Modulation of the effects of quinidine on HERG channel by extracellular potassium ion.
- Dual actions of mibefradil on the volume-sensitive chloride current in cultured human aortic endothelial cells.
- A structural basis for receptor-operated Ca2+ permeable cation channels revealed by chimaeric TRP channels.
- Actions of a novel ATP-sensitive K+ channel opener ZD6169 on voltage-dependent Ca2+ currents in pig urethral smooth muscle.
- Functional study of rat TRP4a protein expressed in HEK-293 cells.
- Modulation by mibefradil of the histamine induced Ca2+ entry in human aortic endothelial cells.
- Structure-activity relationship and molecular modeling analysis of nantenine derivatives, a novel series of potent .ALPHA.1-adrenergic receptor antagonist.
- Dual action of ZD6169, a novel K+ channel opener, on ATP-sensitive K+ channels in pig urethral myocytes.
- cDNA cloning of rat Transient receptor potential-5 (TRP-5) expressed on RBL-2H3 cells.
- Responses of low pH and NO on nicorandil activated IKATP in guinea-pig ventricular myocytes.
- Heteromeric association between adenosine and ATP receptors creates a novel purinergic receptor.
- Inhibitory effect of ferrous ions on increase in intracellular Ca2+ induced by activation of the NMDA receptor channels.
- Presynaptic D2-like receptors selectively block N-type Ca2+ channels to inhibit GABAergic transmission onto rat striatal cholinergic interneurones.
- Extracellular ATP triggers p38 mitogen-activated protein kinase-dependent IL-6 release in mouse microglial cell line, MG-5.
- Characterization of P2Y receptors in cultured rat dorsal root ganglion neurons.
- Effects of extracellular anions on ATP-induced increases in intracellular Ca2+ in NG108-15 and PC12 cells.
- Construction of EGFP-connected P2X2 receptor and its expression.
- Microphysiometric analysis of P2Y-purinoceptor-mediated extracellular acidification in CHO cells.
- Ex vivo binding characteristics of thyrotropin-releasing hormone (TRH) analogues to TRH receptors in rat brain and their pharmacokinetics.
- Nitrooxy alkyl apovincaminate activates K+ currents in rat neocortical neurons.
- The role of GABAA receptors in the antibiotic-induced convulsion.
- 5-HT receptor subtypes on a single GABAergic bouton projecting to the hippocampal CA1 neuron.
- Function of GABAA receptor on intracellular chloride concentration in rat parotid acinar cells.
- mRNA expression of chloride channels (CIC-2,3,4- and 5) in human immune cells.
- Tryptophan scanning mutagenesis in TM2 of the GABA receptor .ALPHA. subunit: effects on channel gating and regulation by ethanol.
- Specific potentiation of .ALPHA.1B (N-type) Ca2+ channel current by a potential antidementia drug, FK960.
- Inhibition by neuroprotective drug NS-7 of voltage-dependent sodium channels: Short- and long-term differential effects.
- Promoter usage of mouse mu opioid receptor gene expression.
- P2Y receptor subtype linked to activation of protein kinase A in bovine adrenocortical cells.
- Functional molecule of ATP-sensitive potassium channel in urinary bladder smooth muscle: Analysis using Kir6.2-knockout mice.
- Disappeared PGE2 induced natriuresis in EP1 receptor gene deficient and specific EP1 receptor antagonist, ONO-8713, treated mice.
- Induction of aquaporin 4 protein in rat otitis media with effusion model.
- Characterization and Purification of novel prazosin binding site in human kidney.
- The N-terminal region of parchorin, a water-secreting cell specific protein, plays a critical role in regulation of its intracellular localization.
- Carboxyl terminus of AQP4 is responsible for its basolateral localization in epithelium.
- Enhanced Ca2+ influx with mossy fiber stimulation in hippocampal CA3 neurons of spontaneously epileptic rats(SER).
- Molecular identification of aquaporin family with ion channel function.
- .ALPHA.-Ryanodine receptor is selectively suppressed in Ca2+-induced Ca2+ release activity in frog skeletal muscle sarcoplasmic reticulum.
- Petrosynol, a novel marine product, is an inhibitor of L-type calcium channel.
- Distinct properties of human .ALPHA.1B(Cay2.2) Ca2+ channel variants lacking II-III linker.
- Antinociceptive action of cilnidipine and amlodipine blocking N-type calcium channels at the primary afferent neurons in mice.
- Effects of cilnidipine on central and peripheral N-type Ca2+ channels expressed in BHK cells.
- Hypotensive effect of Taurine in the salt-sensitive blood pressure increase in the voltage-dependent calcium channel beta3 deficient mouse.
- Chronic exposure of neurons to nicotine induces up-regulation of L-type voltage-dependent Ca2+ channel(VDCC).
- Hyperreactivity of contractile response to carbachol in gastric smooth muscle from type-1 and type-2 diabetic rats.
- The potential regulation of L-type calcium channel by APP family members through the interaction with carboxy terminus of .ALPHA.1c subunit.
- Inhibitory effects of GABA receptor ligands on salivary secretion.
- An automated apparatus for microinjecting genes into Xenopus oocytes.
- Functional importance of .ALPHA.-2 region in Na+/Ca+ exchanger.
- Intramolecular localization of amino acid residues influencing sensitivity to Ni2+ in Na+/Ca2+ exchanger.
- Inhibitory mechanism of amiodarone on Na+/Ca2+ exchange current in CCL39 fibroblast cells.
- Identification of amino acid residues influencing sensitivity to selective inhibitor KB-R7943 in Na+/Ca2+ exchanger.
- Homology modeling of SUR-NBD2 to reveal the mechanism of ADP-dependent KATP channel activity.
- Identification of minimum heme binding domain of soluble guanylyl cyclase and implication for structure of heme packet Identification of minimum heme binding domain of soluble guanylyl cyclase and implications for structure of heme pocket.
- Involvement of Phosphoinositide-Ca2+ Signaling in Osteoclast Differentiation.
- Evidence for little contribution of store-operated Ca2+ channels to Ca2+ entry in cultured bovine adrenal chromaffin cells in response to endothelin-1.
- Characterization of nicotinic acetylcholie receptor involved in (-)-nicotine-induced release of noradrenaline from the isolated rat stomach.
- Role of heat shock protein 90 in the biosynthesis of insulin receptor in adrenal chromaffin cells.
- Expression of kainate receptor in rat adenohypophysis but not in neurohypophysis.
- Properties of ginseng saponin ginsenoside-Rg3 inhibition of catecholamine secretion in bovine adrenal chromaffin cells.
- Phosphorylation of MAP kinase and CREB by nicotine in PC12 cells.
- N-Acetyl-L-Aspartate induced activation of rat acutely dissociated hippocampal neurons via metabotropic glutamate receptors.
- Changes in metabotropic glutamate receptor expression in the basal ganglia of MPTP-treated monkeys.
- Blood pressure, contraction of vascular smooth muscle and feeding behavior of NPY-Y1 receptor knock-out mice.
- Inhibitory effects of psychotropic drugs on salivary secretion.
- Phencyclidine reduces hyperpolarization-activated inward currents (Ih) in hippocampal CA1 pyramidal cells.
- Regulation of Neuropeptide Y receptor gene in the fasting mouse brain.
- H1-Histamine receptor-mediated response in 1321N1 human astrocytoma cells transfected with G .ALPHA..
- Effects of PSD-95 on Src-mediated potentiation of NMDA receptor.
- Differential distribution of inwardly rectifying K+ channels, Kir4.1 and Kir7.1, in retinal pigment epithelial cells.
- High expression of the SK3 channel in the gastrointestinal tract.
- Characterization of the Antiserotonergic activity of rutaecarpine in rat stomach fundus.
- Molecular cloning and tissue distribution of the splice variants of type 2 K+ channel-interacting protein (KChIP2).
- Blockade by nicardipine of the current through Shal-type K+ channels(Kv4.2, Kv4.3L) expressed in HEK293 cells.
- Potentiating effects of PEPA (4-[2-(phenylsulfonylamino)ethylthio]-2,6-difluoro-phenoxyacetamide) on AMPA type of glutamate receptor in rat microglia.
- Functional and Molecular Identification of Voltage-Dependent K+ Channels in Antrum and Fundus Smooth Muscle Cells of the Rat Stomach.
- The kinetic properties of IP3 receptor in permeabilized Purkinje neurons.
- Evaluation of BK channel modulators using a voltage-sensitive fluorescence dye in HEK293 cells.
- Co-expression of large-conductance Ca2+-activated K+ channel and ryanodine receptor type-2 in HEK293 cells.
- The inhibitory effects of 20-hydroxyecdysone, a neurosteroid, on glutamate receptor subtypes in cultured rat retinal ganglion cells: A whole-cell patch clamp study.
- Molecular identification of NAD+- and arachidonic acid-activated Ca2+-permeable channels responsible for Ca2+ influx induced by reactive oxygen species.
- Protease-activated receptor-2(PAR-2)-related peptides trigger tear secretion in the rat: Possible involvement of different mechanisms from PAR-2.
- Dependence on c-Src and Rho family small GPTases in a pathway coupling the a1B-adrenergic receptor to mitogen-activated protein kinase kinase 4.
- Interference of propofol on the Gi/o and Gs protein coupled receptors.
- Involvement of two distinct G-proteins in P2Y receptor-mediated regulation of nifedipine-insensitive Ca2+ currents (NICa) in guinea-pig mesenteric arteriole.
- RGS4 protein confers agonist-dependent relaxation gating to a G protein-gated K+ channel.
- Comparative effects of an inverse agonist prazosin and chemical denervation with reserpine on .ALPHA.1-adrenoceptor in rats.
- Agonist-mediated regulation of the agonist affinity for Gq protein-coupled histamine H1 receptors in human U373 MG astrocytoma cells.
- Analytical approach for effects of RGS protein on G protein-gated potassium channel.
- Systematic search for G protein-coupled receptor genes from human genome database.
- Stimulation of DNA synthesis and proliferation by prostaglandins in primary cultures of adult rat hepatocytes.
- Genetic interaction between calcineurin and myosin.
- Molecular genetic analysis of its4+ gene, which shares an essential function with calcineurin.
- Decrease in Ca2+-ATPase activity in the plasma membranes of rat brain with aging: Involvement of aging-induced brain calcium.
- DNA microarray analysis of gene expression profile in guinea pig eosinophils.
- Growth inhibitory effect of Streptococcal antitumor glycoprotein(SAGP) on human epidermoid carcinoma A431 cells: Involvement of dephosphorylation of epidermal growth factor receptor.
- Molecular interaction of Protein Kinase C.GAMMA. with Diacylglycerol Kinase .GAMMA..
- LAR class PTPases modulate Sema3A-induced growth cone collapse signaling.
- Molecular Cloning, Expression, and Characterization of Novel Calcium/calmodulin-dependent Protein Kinase from a Lower Eukaryote, Physarum polycephalum.
- Stimulation of high-affinity GTPase activity through group II metabotropic glutamate receptors in rat hippocampal and striatal membranes.
- Neuroprotection of estrogen is mediated both through a nuclear estrogen receptor-dependent pathway and through another pathway via extracellular signal-regulated kinase in the rat hippocampus.
- Basic fibroblast growth factor(bFGF) stimulates vascular endothelial growth factor(VEGF) release in osteoblasts: Divergent regulation by p42/p44 mitogen-activated protein kinase(MAPK) and p38 MAPK.
- Studies of histamine H1 receptor down-regulation using mutant receptors lacking putative phosphorylation sites.
- Thrombin activates mitogen-activated protein kinases via transactivation of epidermal growth factor receptor in rat A10 vascular smooth muscle cells.
- Identification of ecto-AMP phosphohydrolase which mediates the P1 antagonist-sensitive ATP response in NG108-15 cells.
- Stimulation of .BETA.3-adrenoceptor causes p38 MAPK phosphorylation in 3T3-L1 adipocytes via cholera toxin-sensitive but not pertussis toxin-sensitive G-proteins.
- The repeated administration of methamphetamine caused an increase of .ALPHA.-adrenergic receptor in mouse brain.
- Diverse Effects of Forskolin and Isoproterenol on the Extracellular Acidification Rate in C6 Glioma Cells as Assessed with a Cytosensor Microphysiometer.
- Role of amiloride-sensitive and voltage-dependent Na+-channel during T cell activation.
- Evidence that secretory granules do not function as intracellular Ca2+ stores in rat parotid acinar cells.
- Different responses of Ca2+ signaling to muscarinic and purinergic receptor activation in acini and ducts of exocrine gland by high speed laser confocal microscopy.
- Intracellular cesium ion potentiates Ca2+ transients induced by depolarization in guinea pig vas deferens smooth muscle cells.
- Muscarinic receptor activation promotes association of tubulin and GRK2 to the plasma membrane in NG108-15 cells.
- Cytochalasin D enhances Fc .EPSILON. RI-induced degranulation by preventing F-actin polymerization in RBL2H3 mast cells.
- Molecular decoding mechanism of Ca2+ oscillation by NFAT.
- Mitochondrial Ca2+ images during depolarization in guinea-pig urinary bladder smooth muscle cells.
- Altered signal transduction through the muscarinic acetylcholine receptor in the hippocampal slices of ischemic rats.
- Inhibition of glutamate release by Rose Bengal, a novel inhibitor of glutamate uptake into synaptic vesicles.
- The involvement of the activation of Ca2+/CaM-regulated enzymes in methacholine-induced amylase secretion in rat parotid glands.
- Role of Akt/protein kinase B activity in induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus.
- Neuroprotective effects of sodium orthovanadate on delayed neuronal death following transient forebrain ischemia through Akt activation.
- Inhibition of ecto-5'-nucleotidase by sodium nitroprusside in C6 glioma cells.
- Manganese superoxide dismutase is an endoplasmic reticulum stress-inducible protein.
- Prevention of peroxynitrite-induced cell death by IGF-1.
- Study of benzodiazepine-induced inhibition of salivary secretion: Effect of chloride on phospholipase C activity in rat parotid glands.
- Involvement of nitric oxide in development of tactile allodynia in the inferior alveolar nerve-ligated rats.
- The essential roles of G .ALPHA.12 and G .ALPHA.13 in endothelin-1-induced activation of MAP kinase leading to hypertrophy.
- Involvement of synapsin I in insulin secretion from insulinoma MIN6 cells.
- Difference in the mechanism to relax porcine coronary artery between isosorbide dinitrate and isoproterenol.
- Regulation of hormone synthesis by cAMP in GH3 cells.
- Essential role of p38 mitogen-activated protein kinase in contact hypersensitivity.
- Phosphorylation of RGS5 protein by protein kinase C.
- Regulation of pituitary hormone gene expression by mitogen-activated protein kinase stimulated with thyrotropin-releasing hormone in GH3 cells.
- Bipasic nuclear translocation of NF-.KAPPA.B induced by interleukin 1 may be regulated via distinct pathways.
- Different mechanisms responsible for collagen-induced activation of human and bovine platelets.
- Clathrin-Box in G Protein-coupled Receptor Kinase 2.
- Translocation of protein kinase C .ALPHA. and .BETA. II isoforms in response to ammonia exposure.
- Amperometric detection and characterization of exocytotic events in single adrenal chromaffin cells.
- Fluvoxamine-induced changes in synaptic efficacy in the cortico-limbic systems in rats.
- Alternation of glycogen metabolism in PRIP KO mice.
- Real time measurement of Ca2+-stimulated inositol 1,4,5-trisphosphate production in cerebellar Purkinje neurons.
- Hydrogen peroxide stimulates big mitogen-activated protein kinase 1 (BMK1) via Src tyrosine kinase in PC12 cells.
- Purification and some properties of the activation of membrane-bound guanylate cyclase, SAT-GC of rat lung.
- Effects of JAK3 inhibitor II on mast cell activation induced by the antigen and thapsigargin.
- Preventive effects by troglitazone on diabetic nephropathy and atherosclerosis in KK and KK/Ay mice feeding with high fructose diets.
- Involvement of IL-6 receptor(R) in the regulation of plasma fibrinogen levels in Triton WR-1339 induced hyperlipidemic rats.
- Effects of Kaihaku and rice vinegar on hyperlipidemia induced by a high-sucrose, cholesterol diet in rats.
- Redox dynamics of .ALPHA.-tocopherol in plasma and erythrocyte membrane of streptozotocin-induced diabetic rats.
- Evaluation of antioxidant action of medicinal herb, Peucedanum japonicum from Okinawa Islands.
- Distribution of mRNA for histamine N-methyltransferase in the guinea pig brain.
- Cancer chemopreventive activity of 4-phenylcoumarins on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
- Reliability of human liver surgical waste donated from cancer patients for the study of drug metabolism.
- Role of chymase in bleomycin-induced pulmonary fibrosis in hamsters.
- Effects of ebselen on hepatic drug-metabolizing enzymes in rats with deoxycholic acid (DCA)-induced liver injury.
- Effects of chronic ethanol in streptozotocin-induced diabetes millitus mice.
- Spatio-temporal analysis of raised intracellular calcium induced by glutamate and of its role in neuronal cell death.
- Histamine metabolism in mouse brain.
- Inhibitory action of h2 and acidic isoforms of calponin on actin-activated myosin Mg2+-ATPase activity.
- Involvement of histone phosphorylation in apoptosis of human astrocytes after exposure to saline solution.
- Comparative studies of monoamine oxidase in rat and guinea pig cerebellum.
- Measurement of solubilized membrane-protein, using bicinchoninic acid(BCA): A device for elimination of interfering substances.
- Molecular mechanism of the suppression of ornthine decarboxylase induction during lung tumorigenic process by vitamin E ether derivative.
- Induction of P-glycoprotein, GST-p and CYP1A2 by Atrazine in rat liver.
- Inhibitory effects of antituberculosis drugs on cytochrome P450 activities.
- Effects of extract of Ginkgo biloba leaves and its terpene constituents on phase II enzyme activities in mouse liver.
- The expression of CYP3A4 mRNA estimated by RT-PCR using radio-labeled primer correlates with CYP3A4 activity and protein level in human liver.
- Effect of cytochrome P450 induction and antioxidants on microsomal glutathione S-transferase of rats.
- Induction of early response gene expression by the retinoid AHPN in human lung carcinoma cells.
- Elevation of steroid 5.ALPHA.-reductase mRNA levels in rat cerebellum by toluene inhalation: Possible relation to GFAP expression.
- Propofol fluidizes model membranes at clinically relevant concentrations and interacts with acetaldehyde condensation products on membrane fluidity.
- Characterization of Pur .ALPHA. protein in brain.
- Heat shock protein 90 inhibitors induce the transient nuclear translocation of dioxin receptor(AhR).
- Translocation and activation of .DELTA.-PKC by the ceramide generation in the interferon-.GAMMA. signaling pathway.
- Elevation of V-1 protein in adrenergic tissues and formation of stomach ulcer in water-restrained rats.
- Analysis of glucose-stimulated insulin secretion in transgenic mice overexpressing PACAP in pancreas and PACAP deficient mice.
- Transport of hibernation-specific protein(HP) through blood-cerebrospinal fluid barrier in rats.
- Study of staurosporine-induced apoptosis in myofibroblasts.
- Binding of SUMO-1 to caspase-2 and its possible cellular/nuclear functions.
- Molecular Mechanisms in Effect of Taurine on Hypoxia-induced Vascular Remodeling.
- Diacylglycerol kinase .ALPHA. and .GAMMA.(DGK .ALPHA. and .GAMMA.) induce neurite-like processes in neuroblastoma cell lines.
- Role of the Prostaglandin E Receptor Subtype EP3 in Angiogenesis in vivo.
- Upregulation of anti-adhesive protein SPARC in mouse hippocampus after kainic acid administration.
- cDNA Cloning of the Immunologically Cross-reactive Substance to Anti-vertotoxin Antibodies from Rat Central Nerves.
- Leptin activates neuropeptide Y gene promoter with STAT3.
- Transgene expression other than target organ in gene therapy.
- Gene manipulation at the early developmental stage by Cre recombinase inserted into the mouse telencephalin gene locus.
- Distribution and localization of translin/trax complex in the nervous system.
- Effect of antioxidants on the activation of hypoxia inducible factor 1.
- Cloning and promoter analysis of 5'-flanking region of cathepsin E gene.
- Construction of advanced One-Step Tet vector.
- Cerebellar Purkinje cell specific and inducible gene recombination system in the Mouse.
- Effect of intracellular histamine on the gene expression profile in mouse bone marrow-derived mast cells.
- Generation of HDC-KO mice and their elimination of E. coli from the peritoneal cavity.
- In vivo cleavage activity of a ribozyme directed against aldose reductase.
- Involvement of Amida in meiosis of spermatogenesis and the phosphorylation by Cdc2 kinase affecting its DNA-binding activity.
- Down-regulation of cardiac aldose reductase expression in streptozotocin-induced diabetic mice.
- Characterization of the novel aldose reductase-related protein in human testis.
- Involvement of gicerin in the formation of microvilli.
- Introduction of dominant negative subunits confirms constraint of subunit composition of the expressed Kv channel by multimerization of the cDNA.
- Characterization of diverse mouse melanoma cell lines by their malignancy using experimental metastatic model.
- GFP-based analysis of the effect of the novel isoform of p27Kip1 on the cell cycle progression.
- The localization of Arc in the nucleus of HEK293T cells.
- Muscle degeneration in caveolin-3-deficient mice.
- Molecular cloning and expression analysis of a novel splice variant of rat sGC .BETA.2 subunit.
- Cloning of mouse Sir genes with homology to the yeast Sir family.
- Identification of a cDNA encoding human homolog of Sec16 protein.
- The transcriptional upregulation of p27Kip1 by the formation of cell-cell contact in the vascular endothelial cells.
- Involvement of neuropeptides in the allergic nasal obstruction in guinea pigs.
- The effects of NK5807, a novel NK2 receptor antagonist, on animal model of asthma.
- Pharmacological studies on the respiratory tract. (Rept. 234). Comparison of the expression of RhoA between bronchial and tracheal smooth muscles of antigen-induced airway hyperresponsive rats.
- Pharmacological studies on the respiratory tract. (Rept. 235). Effect of Y-27632 on acetylcholine-induced Ca2+sensitization of intrapulmonary bronchial smooth muscle of antigen-induced airway hyperresponsive rats.
- Pharmacological studies on the respiratory tract. (Rept. 236). Vasoreactivities of rat isolated nasal mucosa to agonists: Comparison with those of guinea-pig one.
- Induction of Late Asthmatic Response in BN Rats Following Repeated Inhalation Exposure to OVA.
- YM976, a novel phosphodiesterase(PDE) type 4 inhibitor, relaxes bovine tracheal smooth muscle and increases tissue cAMP content.
- Identification of cough response in mice.
- AE-3763, a Novel Inhibitor of Human Neutrophil Elastase. (1). Biochemical and Pharmacological Properties of AE-3763.
- AE-3763, A Novel Inhibitor of Human Neutrophil Elastase. (2). Effects of AE-3763 on Acute Organ Failure Models.
- Protease activated receptor-2(PAR-2) mediated increased in intracellular calcium level in guinea pig tracheal epithelial cells.
- NK5807, a novel non-peptide antagonist of tachykinin NK2 receptor.
- Roles of epithelium H2O2-induced inhibition of acetylcholine-contraction in rabbit intrapulmonary bronchiole.
- cDNA cloning of leukotriene C4 synthase in rat basophilic leukemia-1 cells.
- Contribution of anaphylatoxin C5a to the late airway response induced by repeated antigen inhalation in the allergic rats.
- Role of nitric oxide in the central nervous system on the development of neurogenic pulmonary edema in rats.
- Lidocaine potentiates ANP-induced relaxation of bovine tracheal smooth muscle.
- Ibudilast potentiates cGMP-mediated relaxation of bovine tracheal smooth muscle.
- Studies on intracellular mechanism of bradykinin (BK)-induced inhibition of the M current in the para-tracheal ganglion (PTG) neuron of rats.
- Mechanisms underlying H2O2-induced modulation of mechanical responses induced by acetylcholine in rabbit airway smooth muscles.
- Inhibition of renal glucose reabsorption by a novel SGLT inhibitor, T-1095A and its prodrug, T-1095 in dogs.
- Indoxyl sulfate (IS) induces renal proximal tubular cell damage via organic anion transporter 1 (OAT1).
- Evaluation of organic anion transport inhibitors using cells stably expressing human organic anion transporters.
- Structural and functional changes in kidney in drug (STZ)-induced diabetic rats and spontaneous NIDDM GK rats.
- Effect of Uricosuric Agents on Uric Acid Transport Through Human Organic Anion Transporter 4.
- Renal effects of IRL1620 in anesthetized rabbits.
- Changes in vascular response to various vasoconstrictors in rats with chronic renal failure.
- Effect of PKC and MEK1/2 inhibitors on cephaloridine-induced injury in rat renal cortical slices.
- Attenuation of ischemica/reperfusion-induced renal injury in Na+/Ca2+exchanger-knockout mice.
- Implication of reactive oxygen species and intracellular calcium in cisplatin-induced injury in tubules isolated from the rat kidney.
- Role of endothelin ETB receptor in the pathogenesis of ischemic acute renal failure.
- Effects of gender and estradiol treatment on ischemic acute renal failure in rats.
- Effect of angiotensin II type 1 receptor antagonist at the progressive phase of diabetic nephropathy in rats.
- Effects of anti-fibrotic drug and ACE inhibitor on renal function in type II diabetic db/db mice.
- Necessity of calcium in the early increase in renal kallikrein secretion by potassium.
- Role of renin-angiotensin system in progression of glomerulonephritis.
- Comparison of the inhibitory effect of magnesium supplement and angiotensin converting enzyme inhibitor on chronic cyclosporine A nephrotoxicity in rats.
- Localization of intrarenal angiotensin-converting enzyme(ACE) is different in species.
- A stimulatory effect of potassium ions and ATP sensitive potassium channel blocker on kallikrein secretion from dissected connecting tubles in Sprague Dawley rats.
- Characterization of OPC-51803, a novel non-peptide vasopressin V-receptor agonist, in dogs.
- Analysis of the pressure-natriuresis curve in hypertesive model rats.
- Inhibitory action of butein on intercellular adhesion molecule-1(ICAM-1) expression in PMA-treated human umbilical vein endothelial cell(HUVEC) and its inhibitory mechanisms.
- Involvement of immunoproteasome in disposal of aggregated protein in glomeruli.
- Inhibitory effect of PGE2 on fibronectin(FN) accumulation in glomeruli.
- Analysis of chaperoning activity of Osp94, a hyperosmotic stress sensitive gene.
- Altered expression of purinoceptors and ectonucleotidases genes in the diabetic cardiovascular system.
- Effect of aldose redactase inhibitor, AS-3201 on decreased nerve conduction velocity in diabetic rats.
- Change in neuropeptide Y gene expression by thyroid hormone.
- Effect of low molecular weight chitosan on nephropathy in low dose streptozotocin-induced progressive diabetic mice.
- .BETA.3-adrenergic agonist(BRL37344) suppresses the increased adipose tissue expression of tumor necrosis factor-.ALPHA. in monosodium-L-glutamate-obese mice.
- Influence on proliferation and VEGF production of cultured fibroblasts maintained at long term hyperglycemic condition.
- Effects of dipeptidyl peptidase IV inhibitor, NVP-DPP728 on the glucose tolerance in rats fed a high-fat diet.
- Effect of KAD-1229 on post-prandial hyperglycemia after oral meal load in STZ-induced diabetic rats.
- Spatiotemporal expression of stathmin in the uterus during the peri-implantation period in rats.
- Effects of cyclooxygenase inhibitors on the formation of corpus luteum in rat ovary.
- Effect of low molecular weight chitosan on the progression of diabetes mellitus in KK-Ay mice.
- Toxicological effects of Di-(2-ethylhexyl) Phthalate on hypothalamus-pituitary-gonadal axis in adult female rats.
- Glucose promotes intracellular redistribution of the insulin granules in the pancreatic beta-cell.
- Effect of dantrolene on steroidogenesis in rat, bovine and hamster adrenocortical cells.
- Growth hormone and growth hormone receptor expressions in human immune cells.
- Inhibition of calcium channel current by .KAPPA.-opioid agonist, U50488H, in cultured porcine adrenal chromaffin cells.
- Role of nuclear heat shock protein 90(HSP90) on glucocorticoid-mediated nucleocytoplasmic shuttling and transcription of glucocorticoid receptor(GR).
- Adrenocorticotropic hormone causes Ca2+ influx and cortisol production in zona fasciculata cells.
- Analysis of local denervation induced by accelerated heavy ion irradiation with 125I-metaiodobenzylguanidine(MIBG).
- Effect of papaverine on acetylcholine-induced catecholamine secretion from cultured bovine adrenal chromaffin cells.
- Effects of cannabinoids on norepinephrine release from the rat cardiac sympathetic nerve.
- Possibility that the presynaptic adrenergic .ALPHA. 1 receptor regulate norepinephrine release in male rat urethra.
- Impaired cyclic GMP production in corpus cavernosum of hyperglycemic rabbits and its versal by aldose reductase inhibitor.
- Involvement of mitogen-activated protein kinases in catecholamine synthesis stimulated by leptin in cultured bovine adrenal medullary cells.
- Decreased expression of V-1, a catecholamine biosynthesis-promoting ankyrin repeat protein in bovine adrenal chromaffin cells in culture.
- Estrogenic alkylphenols induce the inhibtion of catecholamine secretion.
- Systemic effects of the peripheral disturbance of the trigeminal system in guinea pigs.
- In vivo muscarinic antagonistic activity of (2R)-N-[1-(6-aminopyridin-2-ylmethyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide, a novel muscarinic M3 receptor antagonist with M2-sparing antagonistic activity in dogs.
- Effects of drugs acting on the central nervous system on bladder hyperactivity induced by clonidine in conscious rats.
- The relationship between aging and sleep apnea in male and female rats.
- Ex vivo binding characteristics of a novel anticholinergic agent, YM-905, to muscarinic receptors in mouse tissues.
- Modification of pilocarpine-induced fluid and protein secretion from rat submandibular gland by selective adrenoceptor antagonists.
- Characteristics of post-tetanic contraction induced by naloxone in isolated guinea pig ileum.
- Involvement of nitric oxide in spontaneous itch-scratch behavior of mouse with cutaneous barrier disruption.
- Nociception and allodynia/hyperalgesia induced by intrathecal administration of fenvalerate.
- Itch-associated facial scratching and antinociception induced by intracisternal morphine-6.BETA.-glucuronide in mice: Comparison with morphine.
- Phosphoramidon potentiates the antinociceptive effect of intracerebroventricularly administered dynorphin A.
- A tetrapeptide of dermorphin analogue produces an extremely potent antinociceptive effect in mice.
- The role of spinal nitric oxide in nociceptive behavior evoked by high dose intrathecal morphine in rats.
- Effect of carbamazepine on fenvalerate-induced nociceptive responses in mice.
- Effect of isoflurane on Mongolian gerbils.
- Developmental changes in the inhibitory effect of morphine 6-glucuronide on tail-flick response of rats.
- Characterization of the protease-activated receptor-2-mediated pain modulation.
- Metabolism of endomorphin-2 by synaptic membranes of mouse brain.
- Studies on drug dependence(Rept. 358): Possible involvement of MOR1B, a .MU.-opioid receptor splicing variant-derived protein, in the antinociceptive action induced by .MU.-opioid receptor agonists.
- Effects of nociceptin and its related peptides on capsaicin-induced desensitization.
- Carrageenan-induced experssion of prepronociceptin mRNA in VR1-positive neurons in rat dorsal root ganglia.
- The spinal antinociceptive effect of FR140423 is mediated through kyotorphin receptors.
- Effects of three peptidase inhibitors on antinociceptive action of [Met5]-Enkephalin-Arg6-Phe7 in rats.
- Presence of nociceptin receptors in rabbit sphincter muscle iris: Comparison with receptors in mouse vas deferens.
- Effects of somatic and visceral noxious stimuli on the expression of c-fos mRNA and extracellular glutamate level in amygdala.
- Antinociceptive effect of intracerebroventricular P2-purinoceptor agonists in rats: Involvements of .BETA.2-adrenergic and .MU.-opioid receptors.
- Involvement of brain monoamine receptors in analgesic effect of antidepressants.
- Influence of Chemical Denervation of Descending Monoaminergic Inhibitory Pathways on Analgesic Effect of Neurotropin in SART-stressed Rats.
- The involvement of muscarinic acetylcholine receptors in clonidine-induced analgesia in the spinal cord of rats.
- The responses to noxious stimuli in mice lacking .ALPHA. 1D-adrenergic receptors.
- Analgesic methods to elucidate the tonic physiological pain: Usability of ovariectomized(OVA) and streptozotocin(STZ)-diabetic rat.
- Effect of mexiletine on substance P release and extravasation evoked by noxious heat stimulation of the rat hind instep.
- Subcutaneous, intrathecal and intracerebroventricular administration of morphine significantly increased analgesia in histamine H1 receptor knockout mice.
- In vitro and ex vivo effects of J-113397(a selective antagonist of nociceptin receptor) on specific [3H]nociceptin binding in rat brain and spinal cord.
- Peripheral and spinal mechanisms of .ALPHA.,.BETA.-methylene ATP-induced mechanical allodynia in rats.
- Reduction of acute herpetic pain in mice lacking prostaglandin EP3 receptors.
- Effects of gabapentin on neurogenic and inflammatory nociception in mice.
- Changes in spinal neurotransmissions in a rat experimental model for chronic neuropathic hyperalgesia.
- Role of nitric oxide in the pathogenesis of nociceptive threshold changes in streptozotocin-induced diabetic mice.
- Effects of nociceptin and [Nphe1]nociceptin(1-13)-NH2 on mechanical allodynia induced by nerve constriction injury in the rat.
- Effect of 5-HT2A receptor antagonists on hyperalgesia in neuropathic pain model rat.
- Lack of the development of antinociceptive tolerance to morphine and U-50, 488H in neuropathic pain model mice following a partial sciatic nerve ligation.
- Effects of Naltrexone on Excitation of Dopa minergic Neurons Induced by Acute Ethanol Administration.
- Suppressive Effects of Trihexyphenidyl on Methamphetamine-Induced Dopamine Release in Mouse Nucleus Accumbens.
- Effects of the acute administration of methamphetamine on the amino acid contents in the brain of the histidine decarboxylase gene knockout mice.
- Behavioral effects of morphine and methamphetamine in mice lacking NMDA receptor .EPSILON. 1 subunit.
- Role of protein kinase C in the inhibition of tolerance development to morphine analgesia in the presense of chronic pain.
- Changes in G protein-activated inwardly rectifying potassium channel proteins levels in morphine-dependent mice.
- Role of corticotropin-releasing factor receptor-1 in morphine-induced hyperlocomotion.
- Studies on drug dependence(Rept. 359): Pharmacogenetic analysis of morphine-induced rewarding effect and physical dependence in the SMXA recombinant inbred of mice.
- The gene expression of kappa opioid receptor in the brain of butorphanol-dependent and withdrawn rat.
- A role of tumor necrosis factor-.ALPHA.(TNF-.ALPHA.) in behavioral effects of methamphetamine.
- Alternation of G-protein activity by repeated morphine treatment in the presence of chronic pain.
- Inhibition of morphine tolerance and dependence by MS-153, a glutamate transporter activator.
- The protective effect of .ALPHA.-tocopherol transfer protein on presenilin-related cell death in PC12 cells.
- Prolonged exposure to low concentration of beta-amyloid protein makes neurons vulnerable to excitotoxic damage.
- Protective effect of memantine against beta amyloid plus glutamate-induced neurotoxicity in cultured rat cerebral cortical neurons.
- Phosphatidylinositol 4-kinase: Decreased expression in the rat hippocampus after brain ischemia.
- Regulation of NMDA-induced current and cell death by neurosteroids in cultured cortical neurons.
- Involvement of nitric oxide overproduction and inflammation in amyloid .BETA.-peptide-induced brain dysfunction.
- Reduction of Neprilysin(Neutral Endope-ptidase 24.11) Activity in Brain Contributes to Deposition of Alzheimer's Amyloid-.BETA. Peptide.
- Humanin, a novel gene encoding 24 amino acid polypeptide inhibits cell death by Alzheimer's disease-related insults.
- Role of ERK in protection by glia-derived factors against amyloid .BETA.-induced neuronal death.
- Neural substrates for nausea using conditioned taste aversion technique in Suncus murinus.
- Effects of nicotine on hippocampal neurons.
- Bradykinin stimulates phosphorylation of synapsin I in PC12 cells.
- Nitric oxide produced by inducible nitric oxide synthase is involved in the mechanism of late ischemic preconditioning in rat retinal neurons.
- The effect of estrogen and the related compounds on CA3-mossy fiber synapses.
- Second messenger system in 5-HT4 receptor-mediated depolarization in hippocampal CA1 neurons.
- SUN N8075, a novel neuroprotectant possessing dual blocking actions on Na+ and T-type Ca2+ channels with antioxidant properties.
- PB-2, an extract of lichen, enhances the hippocampal long-term potentiation in anesthetized rat in vivo.
- Paraquat Taken up into Striatal Cells Induced Transit Glutamate Efflux Followed by the Long-Term Dopamine Overflow.
- Neuroprotective effect of a central type prostacyclin receptor ligand in a rat model of focal cerebral ischemia.
- Chronic model of rat focal ischemia.
- Involvement of central 5-HT4 receptors in cholinergic function associated with cognitive processes.
- Centrally administered SIN-1, an NO donor, elevates the release of noradrenaline in the hypothalamic PVN and the plasma levels of corticosterone in rats.
- Brain inducible nitric oxide synthase is involved in interleukin-1.BETA.-induced central activation of sympathetic outflow in rats.
- 5-HT1A receptor-mediated inhibition by tandospirone of medial vestibular nucleus(MVN) neurons receiving otolith inputs.
- Measurement of cerebral blood flow by Transcranial Doppler ultrasonography(TCD). Experimental study on thromboembolic stroke in cynomolgus monkeys.
- Binding characteristics of selective serotonin reuptake inhibitors on brain serotonin transporter after the oral administration.
- The NMDA receptor glycine-binding site antagonist, SM-31900, reduces cerebral infarct volume in SHRs subjected to permanent middle cerebral artery occlusion.
- Action Profile of Clobazam on Two Types of Seizures in Ihara Epileptic Rats(IERs).
- Atypical antipsychotic properties of NRA0562.
- Neuropharmacological properties of novel group II mGluR agonists, MGS0008 and MGS0028.
- Identification of a novel gene decreased after chronic electroconvulsive treatment in rat frontal cortex.
- Effect of adrenocorticotropic hormone(ACTH) on serotonin release in the rat hippocampus from aspects of depression.
- The effect of SUN N8075, a novel neuroprotectant, on functional impairments in rats subjected to transient middle cerebral artery occlusion.
- Rho-associated kinase phosphorylates MARCKS in human neuronal cells.
- Glial activation in the experimental prion disease affected mouse brain.
- Effect of T-588 on mitochondrial function and cell death of cultured astrocytes.
- PrP fragment 106-126 is toxic to brain endothelial cells and inhibits efflux pumps at the blood-brain barrier.
- In vitro effects of pentosan polysulphate on the blood-brain barrier under physiological and pathological conditions.
- Effect of microglia on cell death of PC12 cells induced by NGF withdrawal.
- Cyclic AMP activates P-glycoprotein and MRP-1 efflux pumps at the blood-brain barrier.
- Effects of LPS and cytokines on mitochondrial activity in microglia.
- Effect of ET-1 on gene expression of ET-1 and neurotrophic factors in cultured rat astrocytes.
- Two Distinct Intracellular Pathways of Glycine Release in Rat Spinal Interneurons.
- The effect of gabapentin on the mono- and polysynaptic spinal reflexes in rats.
- Effect of nociceptin/orphanin FQ on the entrainment function of the suprachiasmatic nucleus in rats.
- Pathologically and pharmacologically induced tolerance to ischemia in rat hippocampal slice preparations.
- Development of a novel intracellular calcium measurement system with microtiterplate.
- c-fos expression in rat area postrema and nucleus tractus solitarius: Involvement in drug-induced emesis.
- Are glycine receptors involved in micturition reflex?
- Action of Brotizolam on Circadian and Light-induced Per1 and Per2 Expression in the Hamster Suprachiasmatic Nucleus.
- Pentylenetetrazol kindling modulates the regional expression of c-Fos-related proteins in the mice brain.
- Aconitine facilitates spontaneous GABA release from presynaptic nerve terminals projecting to ventromedial hypothalamic neurons of the rat.
- Role of a Na+/H+ exchanger on glutamate induced morphological changes in rat cultured cortical neurons.
- Differential expression of a novel Rho-kinase like gene after chronic antidepressant treatment revealed by ADRG-microarray.
- The effect of pentylenetetrazole(PTZ) on the release of glutamate and GABA in the rat brain.
- Differential pharmacological properties of presynaptic and somatodendritic P2X receptors in the nucleus tractus solitar ii of the rat.
- [3H]Spermidine uptake by cultured astrocytes from rat cerebral cortex.
- Modulation of Multisynaptic Transmission in the Native Hippocampus Network by Extracellular ATP.
- ATP inhibition of Glutamate Release and Nitric Oxide Production in Cultured Microglia Stimulated by Lipopolysaccharide.
- Effect of B6 vitamers on .ALPHA. .BETA.-methylene ATP binding in mouse crude synaptic membranes.
- Hypersensitivity to dopamine of dopaminrgic receptors of nucleus accumbens neurons following repeated treatment with methamphetamine: A slice patch-clamp study.
- The recovery of motor function and dopaminergic parameters in mouse model of Parkinson's disease.
- Nicotinic transmission mediated by nicotinic receptors bearing alpha4 subunit in dopaminergic neurons of sustantia nigra.
- L-dopa butyl ester exerts anti-Parkinsonism effect and increases L-dopa content in the striatum in a manner similar to that of L-dopa in the rat.
- Administration of muscimol into the nucleus accumbens shell disinhibits both mesolimbic dopaminergic and hypothalamic orexin neurons.
- Release of 5-hydroxytryptamine from the medial vestibular nucleus in rats.
- The release of acetylcholine in the striatum increased on the treatment of levodopa through the activation of dopamine D1 receptors.
- The electrophysiolgical analysis of orexin neurons.
- Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy, Hypophagia and Obesity.
- Developmental changes in Cl--ATPase activity in rat brain.
- Effect of a Na+/H+ exchanger inhibitor, SM-20220, on ischemic brain damage and edema in the rat thrombotic middle cerebral artery occlusion model.
- Cellular and subcellular localization of Cl- pump 55kDa subunit in the rat brain.
- Reduced neuroprotective efficacy of an NMDA receptor antagonist in aged rats compared with young rats: Studies in a rat model of thrombotic middle cerebral artery occlusion.
- Effects of clobazam, a novel antiepileptic drug, on abnormal excitability of CA3 pyramidal neurons in spontaneously epileptic rats(SER).
- Abnormal excitability of hippocampal CA1 and CA3 neurons in Spontaneously Epileptic Rats(SER).
- Role of extracellular signal-regulated protein kinase(ERK) in LPS-induced decrease of [3H]-thymidine incorporation in microglia.
- Functional roles of histamine neurons in acute and chronic stresses.
- Protective effects of pamiteplase, a modified tissue-type plasminogen activator in a rat thromboembolic stroke model.
- Biochemical mechanism in neuroprotective properties of immunophilin ligands.
- Antidepressant activity of non-peptide corticotoropin-releasing factor receptor subtype 1 antagonist CRA 1000.
- The suppression of brain/serum ratio after systemic morphine by L-type Ca2+ channel blockers in mice.
- Antisense oligonucleotides to c-fos reduce the seizure susceptibility after ethacrynic acid(EA)-induced seizures in mice.
- Effect of zinc ion on the uptake and metabolism of L-histidine in rat blood-brain barrier.
- The Rational Drug Design and Antitussive Effects of a Novel Opioid .DELTA.-Receptor Antagonist TRK-851.
- Mechanisms underlying hypothermia induced by intracerebroventricular injections of bombesin.
- Methylphenidate improves short-term memory deficit and hyperactivity in stroke-prone spontaneously hypertensive rats.
- Effects of desipramine and Lithium carbonate on the forced swimming test and 5-HT2 receptor mediated wet-dog shakes in ACTH-treated rats.
- Effect of astaxanthin on daily rhythm of locomotor activity in rats.
- Effect of fluvoxamine on the anxiolytic and adverse effects of benzodiazepines.
- A quantitative method to determine the pica behavior in mice.
- Effects of essential oil aromatics in conflict behavior in rats.
- Corn oil-induced conditioned place preference, and dopaminergic and opioidergic mediation.
- Combined effects of nicotine and L-DOPA on parkinsonian syndrome in MPTP-treated crab-eating monkeys and common marmosets.
- Nicotine blocks apomorphine-induced climbing behavior in mice; Involvements of .ALPHA.7-nicotinic and NMDA receptors.
- Nicotine blocks apomorphine-induced disruption of prepulse inhibition in rats; Involvements of .ALPHA.-nicotinic receptors.
- Effects of cigarette smoke on cell size and succinate dehydrogenase activity of fibers in the extensor digitorum longus and soleus muscles in spontaneously hypertensive rats.
- Inhibitory effects of TRK-820 on systemic skin scratching induced by intravenous morphine in rhesus monkeys.
- Role of AMPA and NMDA receptors in the nucleus accumbens in the production of rat turning behaviour.
- Endogenous allopregnanolone physiologically regulates the GABAA receptor function in the mouse brain.
- Involvement of the dorsal midbrain in aggressive behaviors induced by ventromedial hypothalamus-lesion in rats.
- Effects of centrally-acting drugs on tail-swing behavior in mice.
- Anti-aggressive effect of MKC-242, a 5-HTIA receptor agonist, in socially isolated mice: Possible involvement of dopamine neurons.
- Withdrawal from Repeated and Chronic Morphine Administration Cause Differential Changes in Immobility in Rat Forced Swimming Test.
- Role of GABAA receptors in the retrorubral field in the production of rats jaw movements.
- Implication of nitric oxide-dependent pathway in anxiety disorders after stroke.
- Behavioural and neurochemical characterisations of spontaneously hypertensive rats.
- Antitussive effect of WIN 55212-2, a cannabinoid receptor agonist.
- Effect of nilvadipine, L-type Ca2+-channel blocker, on repeated cerebral ischemia-induced imparment of spatial cognition in rat.
- Characteristics of learning and memory impairment after transient middle cerebral artery occlusion in ddY mice.
- Effects of hypothermia and hyperthermia on learning and memory impairment following neonatal hypoxic-ischemic insult in rats.
- Behavioral suppression induced by .DELTA.8-THC is due to signaling via prostanoid EP3 receptor.
- Effect of magnesium administration on the enhancement of dopamine-dependent brain function elicited by calcium.
- Identification of a novel anti-depressive substance extracted from Perillae Herba.
- A possible involvement of the chorda tympani in the activation of the histaminergic system by leptin.
- Intrathecal histamine elicits a scratching, biting and licking behavior in mice.
- Neuropharmacological Properties of TAK-375, a Novel Melatonin ML, Receptor Agonist.
- Effects of TAK-375, a Novel Melatonin receptor agonist, on Sleep in Freely Moving Monkeys at Nighttime.
- Sleep-Promoting Action and Pharmacological Effects of TAK-375, a Novel ML1-Selective Melatonin Receptor Agonist, in Experimental Animals.
- Impairment of biosynthesis of catecholamines and serotonin in tetrahydrobiopterin-deficient mice.
- Potentiation of neurotransmitter release from rat nucleus accumbens by reactive blue 2 and cibacron blue 3GA.
- Isatin, an endogenous MAO inhibitor, increased in DA levels a rat model for Parkinson's disease.
- Effects of L-3,4-dihydroxyphenylalnine(L-DOPA) on Caenorhabditis elegans Behavior, and Isolation and Characterization of L-DOPA Response abnormal Mutants.
- ESR study on free radical scavenging and/or generating activity of dopamine-4-O-sulfate.
- Effects of NGF on the transcriptional regulation of rat norepinephrine transporter gene.
- Involvement of PRIP1 in GABAA signaling.
- Distribution of the high-affinity choline transporter in the central nervous system of the rat.
- Role of metabotropic glutamate receptors on the release of acetylcholine in the rat striatum. An in vivo microdialysis study.
- Effects of morphine on spontaneous population spikes recorded with multi-electrode dishes in cultured rat hippocampal slices.
- Role of nitric oxide in sympathetic neurotransmission in the rat kidney.
- A new strategy in search for specific dopamine D receptor agonists and antagonists.
- The mechanism of emesis mediated by tachykinin NK-1 receptors in ferrets.
- Mechanisms underlying release of calcitonin gene-related peptide(CGRP) induced by perivascular nerve stimulation in rat mesenteric resistance arteries.
- Neuropeptide Y-induced contraction differs between large and small coronary arteries in porcine.
- Effects of arginine vasopressin and related compounds on regional cerebral blood flow in spontaneously hypertensive rats.
- Chronic Carbamazepine Down Regulated Calcineurin and Increased Phosphorylation of GAP-43 and Marcks.
- Improved learning and memory in the basal forebrain lesioned rats with chronic administration of (-)-nicotine.
- Selective change in Ca2+/CaM-sensitive adenylyl cyclase after microsphere embolism in rats.
- Interaction between cholinergic and GABAergic neurotransmission on passive avoidance learning in rats.
- Adenoviral-driven gene expression of leukemia inhibitory factor in the medial septum/diagonal band impaires spatial learning in mice.
- Synergistic effect of forskolin and adenosine A1 receptor antagonist on synaptic transmission in the rat hippocampal slices.
- Paeoniflorin reverses adenosine-induced inhibition of long-term potentiation in rat hippocampal CA1 region.
- Arcadlin colocalizes and interacts with N-cadherin at activated synapse.
- Effect of morphine on synaptic transmission and synaptic plasticity in the rat hippocampal slices.
- Involvement of muscarinic receptor on the impairment of avoidance learning in mice fed a thiamine-deficient diet.
- The neuronal mechanism of enhancement of learning and memory in the nociceptin receptor knockout mice.
- Involvement of k-opioid receptor on memory function using antisense oligodeoxynucleotides for KOR-1.
- Involvement of endogenous cannabinoid ligands on .DELTA.9-tetrahydrocannabinol-induced impairment of spatial cognition.
- Endogenous GLP-1 exacerbates .BETA.-amyloid protein-induced impairment of LTP through cAMP-independent mechanism in the rat CA1.
- A Study on the Mechanism for Ameliorating Effect of Novel NC-1900 on Passive Aboidance Behavior.
- Mechanism of MK-801-induced animal model for early Alzheimer's disease: Detection of acetylcholine release in rat cortex with in vivo microdialysis.
- Characteristics of brain dysfunction following bilateral coinjection of .BETA.-amyloid peptides and ibotenate into the hippocampus.
- Effect of Kami-untan-to(KUT) on learning and memory impairment induced by thiamine deficient feeding in mice.
- Involvement of the cholinergic system on the impairment of avoidance learning in mice fed a magnesium deficient diet.
- Effects of scopolamine injections on the Sidman-type avoidance learning in rats.
- Effect of systemic treatment with MK-801, an early stage model of Alzheimer's disease, on CCK neurons in rat brain regions.
- Influence of histidine-deficient diets on radial maze performance in rats.
- Regulation of cell adhesion and neurite outgrowth by integrin-linked kinase in N1E-115 cells.
- A sarcoglycan complex in the peripheral nervous system.
- Endothelin induces tyrosine phosphorylation of connexin 43 and reduces gap junctional communication in rat cultured astrocytes.
- Differentiation of neural stem cells into smooth muscle cells.
- Altered monoaminergic functions in mice lacking neuropeptide PACAP.
- Effect of troglitazone on neuronal death.
- Comparative analysis of immunohistochemical distributions of tyrosine hydroxylase, calmodulin and calcium/calmodulin-dependent protein kinase II in the rat brain.
- Structure and function of F-actin bundles formed by fascin.
- Involvement of Cyclin-dependent Kinase 5 in Semaphorin-3A Signaling.
- Effect of green tea on oxygen-induced retinal neovascularization in the neonatal rat.
- Role of Endothelin in ischemia-related neuronal death.
- Brain-derived neurotrophic factor regulates the GABAergic synapse formation in cultured hippocampal neurons.
- cAMP-dependent protein kinase A signaling pathway is required for a target-specific axon guidance of hippocampal mossy fibers.
- Alterations in emotional behaviors and brain serotonergic nervous system in streptozotocin-induced diabetic rats.
- Increased extracellular acetylcholine in the rat frontal cortex during the performing of a conditioning task.
- Pharmacological characterization of 5-HT receptors involved in fluvoxamine-mediated synaptic transmission in the rat hippocampal CA1 and CA3 fields.
- Changes in the brain function in the new aging model, klotho gene mutant mice.
- Roles of voltage-gated Ca2+ channels in neurite-derived necrosis of mouse dorsal root ganglion neurons.
- Effect of S-allyl-L-cysteine on amyloid .BETA.-peptide-induced neuronal cell death in cultured rat hippocampal and cerebellar granule neurons.
- Phagocytosis of apoptotic cells drives microglia to produce prostaglandin E2.
- Endothelin Reduces the Expression of Glial NA+-Dependent L-Glutamate Transporter in cAMP-Stimulated Astrocytes in Vitro.
- .BETA.-amyloid 25-35 neurotoxicity is mediated by both caspase-8 and caspase-9 but not by caspase-3 in PC12 cells.
- Heat stress attenuates reperfusion-induced delayed apoptosis of cultured rat astrocytes.
- Amyloid .BETA. protein activates the p44/42 mitogen-activated protein kinase cascade in cultured rat cortical astrocytes.
- Identification of the extraneuronal monoamine transporter in human astrocytes.
- Characterization and possible functions of cathepsin H expressed in activated microglia.
- Increase in production of glial cell line-derived neurotrophic factor by concanamycin A.
- Mechanisms of estrogen-induced IGF-1 mRNA expression in hippocampal neurons.
- Effects of estrogen on neuronal cell death in several models of primary cultured cerebellar granule cells.
- Involvement of nitric oxide in some pharmacological actions of nerve growth factor on sensory neurons.
- Expression of neurotrophic factors in chronic constrictive injury model.
- Scabronines promote the synthesis of neurotrophic factors accompanied by the activation of protein kinase C .XI. in 1321N1 human astrocytoma cells.
- Kanokodiol, an enhancer of nerve growth factor action from Valeriana fauriei in PC12D cells.
- Enhancement of action of neuritogenic substances by picrosides I and II from Picrorhiza scrophulari iflora in PC12D cells.
- NGF induces neurite outgrowth via a decrease in phosphorylation of myosin light chain in PC12 cells.
- Effects of endogenous GLP-1 on neurite elongation in rat primary cultured hippocampal neurons.
- Activation of Nuclear Ca2+/Calmodulin-Dependent Protein kinase II and Expression of BDNF by dopamine D2 receptor.
- Molecular mechanism involved in cell death of cultured microglial cells.
- Role of endogenous cellular PACAP in glutamate-induced gene expression and cell death of cultured neurons.
- Structure-activity relationship of arylethanolamine and aryloxypropanolamine drugs at .BETA.3-adrenoceptor on the guinea pig gastric fundus.
- .ALPHA.1-Adrenoceptor subtypes and effects of bus-pirone in the mouse thoracic aorta.
- Inhibitory effect of 2-aminoethoxydiphenyl borate(2-APB) on contractile response to acetylcholine of muscularis mucosae isolated from the guinea-pig esophagus.
- Further characterization of .BETA.3-adrenoceptors in the guinea pig gastric fundus: Stereoselectivity and .BETA.-adrenoceptor alkylating.
- Isoproterenol-induced relaxation in gastric smooth muscle of SHRSP.
- Role of BK channel in the rhythmic contraction of urinary bladder smooth muscle isolated from guinea-pig.
- Reduced relaxant responses to cyclic GMP-K+ channel pathway in guinea-pig aorta contracted with a thromboxane A2 mimetic, U46619.
- Age-Related Changes in the Reactivity in the Rat Intestine to Cholinoceptor Agonists.
- Inhibitory effects of procaine and related compounds on ACh-induced contraction in guinea-pig ileal longitudinal muscle.
- Distribution of oxytocin receptors in the porcine myometrium.
- Involvement of accumulated endogenous NOS inhibitors and decreased NOS activity in the impaired neurogenic relaxation of the rabbit proximal urethra with ischemia.
- Roles of ryanodine-sensitive Ca2+ release in mouse gastric smooth muscle function.
- Stage specific regulation of myometrial contractile response by different P2 receptor subtypes in the rat uterus during the course of pregnancy.
- Contractile activities of vascular smooth muscle cells of which myosin light chain kinase was down-regulated.
- Effect of H2O2 on membrane potentials and mechanical activities in rabbit intrapulmonary bronchiole.
- Characterization of endothelin-1(ET-1) receptors in human Fallopian tube.
- Expression of Subfragment 1 of Physarum myosin.
- Tachykinin receptors responsible for the contraction of the rabbit corpus cavernosum.
- Mechanism of the trypsin-induced contraction in the rat myometrium.
- In vitro characterization of prostanoid receptors in the nonpregnant porcine myometrium.
- Effects of adenosine- and P2-receptor antagonists on the penile tumescence in the anesthetized dogs.
- Pharmacological profile of T-0156, a newly synthetized phosphodiesterase type 5 inhibitor, in anesthetized dogs.
- A beneficial effect of leukotriene D4 on ileal muscle contraction through M3 muscarinic receptor in guinea-pig.
- Differential effect of phorbol ester on cytosolic Ca2+ level and contraction in human and rat myometria.
- Effect of FR226807, a selective phosphodiesterase 5 inhibitor, on the attenuated responsiveness of the corpus cavernosum in middle-aged and streptozotocin-induced diabetic rats.
- A model for measurement of penile erectile response to drugs in conscious rats.
- Effects of a membrane permeable inhibitor of IP3 receptor, xestospongin C, on smooth muscle cells.
- Possible contribution of NO production by iNOS in endotoxin-induced ocular inflammation to the regulation of muscle tone of rat iris sphincter.
- Effect of 2,5-dimethylpyrazine obtained from adrenal gland on uterine contraction of female rats.
- Mechanisms of vanadate-induced contraction in ileal longitudinal smooth muscle of guinea-pig.
- New Regulatory Mechanism of Smooth Muscle Contraction: Examination of Phosphorylated Myosin Light Chain Kinase.
- Reconstitution of spontaneous tone mediated by calcium influx in three-dimensionally cultured smooth muscle cells of basilar artery.
- Agonist-induced contraction of reconstituted fiber of cultured smooth muscle cells derived from rat middle cerebral artery.
- Reconstitution of rhythmic contractions in three-dimensionally cultured gastric smooth muscle cells after co-culture with c-kit positive interstitial cells.
- Effects of H2O-extract of oriental medicinal plant Leonuri herba on phenylephrine-induced contraction in the isolated rat aorta.
- Hypoxia-induced mirror-image alteration in levels of V-1 protein and myosin in the guinea pig taenia caeci.
- Adenovirus-mediated over-expression of Rho induces spontaneous tone mediated by extracellular calcium in three-dimensionally cultured smooth muscle cells of basilar artery.
- Nitric oxide(NO) induces[45Ca2+] influx via L-type voltage-dependent Ca2+ channels(VDCCs) activation in bladder smooth muscle cells.
- Histamine H2-receptor antagonists raises bioavailability of acetaminophen by inhibiting the first-pass glucuronidation in human.
- Evaluations of sedation induced by antihistamines: The comparative study between ebastine and d-chlorpheniramine using positron emission tomography(PET).
- Comparative pharmacokinetics of antiarrhythmics by single or repeated administration in the pregnant rabitts and fetuses.
- Effects of furanocoumarin derivatives in grapefruit juice on nifedipine pharmacokinetics in rats.
- Highly enhanced disruption of blood-brain barrier permeability by repeated intracisternal administration of ET-1 in dogs.
- A human PET study revealed orally administrated d-chlorpheniramine significantly changed the brain activity during visual discrimination task.
- Impact of drug absorption on chronopharmacokinetics. A study using an electrogastrography.
- Levodopa/benserazide tablets showed higher bioavailability of levodopa than levodopa/carbidopa tablets.
1
- The Biological Role of Non-neuronal Acetylcholine in Plants and Humans.
- An Independent Non-neuronal Cholinergic System in Lymphocytes.
- Roles of Muscarinic Acetylcholine Receptors in Interleukin-2 Synthesis in Lymphocytes.
- Non-neuronal Neurotransmitters and Neurotrophic Factors in Amniotic Epithelial Cells: Expression and Function in Humans and Monkey.
- The Non-neuronal Cholinergic System in the Endothelium: Evidence and Possible Pathobiological Significance.
- The Role of Oxygen-Derived Free Radicals in Augmented Relaxations to Levcromakalim in the Aorta From Hypertensive Rats.
- (.+-.)-Pindolol Acts as a Partial Agonist at Atypical .BETA.-Adrenoceptors in the Guinea Pig Duodenum.
- Characterization of Prejunctional Purinoceptors Inhibiting Noradrenaline Release in Rat Mesenteric Arteries.
- Mechanisms Underlying the Induction of Vasorelaxation in Rat Thoracic Aorta by Sanguinarine.
- Modulation by Cyclic AMP and Phorbol Myristate Acetate of Cephaloridine-Induced Injury in Rat Renal Cortical Slices.
- Existence of Retinoic Acid-Receptor-Independent Retinoid X-Receptor-Dependent Pathway in Myeloid Cell Function.
- Possible Involvement of 5-HT4 Receptors, in Addition to 5-HT3 Receptors, in the Emesis Induced by High-Dose Cisplatin in Suncus murinus.
- Species- and Temperature-Dependency of the Decrease in Myofilament Ca2+ Sensitivity Induced by .BETA.-Adrenergic Stimulation.
- Suppression of Gingival Inflammation Induced Porphyromonas gingivalis in Rats by Leupeptin.
- The Role of Nitrergic System in Lidocaine-Induced Convulsion in the Mouse.
- Inhibition of Concanavalin A-Induced Mice Hepatitis by Coumarin Derivatives.
- The Mechanism of Maitotoxin-Induced Elevation of the Cytosolic Free Calcium Level in Rat Cerebrocortical Synaptosomes.
- Rhein, an Active Metabolite of Diacerein, Suppresses the Interleukin-1.ALPHA.-Induced Proteoglycan Degradation in Cultured Rabbit Articular Chondrocytes.
- Guinea Pig Histamine N-Methyltransferase: cDNA Cloning and mRNA Distribution.
- Is Compensatory Vasoconstrictor Tone in the Hindquarter Vascular Region Induced by Hemorrhage in Conscious Spontaneously Hypertensive Rats?
- Effect of Prolonged Nitric Oxide Synthesis Inhibition on Plasma Fibrinogen Concentration in Rats.
2
- Characterization and Application of a Gastric Surface Mucous Cell Line GSM06 Established From Temperature-Sensitive Simian Virus 40 Large T-Antigen Transgenic Mice.
- Nitrooxy Alkyl Apovincaminate Activates K+ Currents in Rat Neocortical Neurons.
- Nitric Oxide Donating Compounds Inhibit HCl-Induced Gastric Mucosal Lesions Mainly via Prostaglandin.
- Involvement of Prostaglandin E2 in Clearance of Aggregated Protein via Protein Kinase A in Glomeruli.
- Regulation of Endothelial Nitric Oxide Synthase and Endothelin-1 Expression by Fluvastatin in Human Vascular Endothelial Cells.
- Effects of Chondroitin Sulfate on Colitis Induced by Dextran Sulfate Sodium in Rats.
- Beta1-Adrenergic Agonist Is a Potent Stimulator of Alveolar Fluid Clearance in Hyperoxic Rat Lungs.
- Interactions of Ligands at Angiotensin II-Receptors and Imidazoline Receptors.
- The Anti-inflammatory Effect of FR188582, a Highly Selective Inhibitor of Cyclooxygenase-2, With an Ulcerogenic Sparing Effect in Rats.
- Hemodynamic Effects of Synephrine Treatment in Portal Hypertensive Rats.
- Anxiety-Like Behavior in Elevated Plus-Maze Tests in Repeatedly Cold-Stressed Mice.
- Disturbance of Circadian Rhythm in Heart Rate, Blood Pressure and Locomotive Activity at the Stroke-Onset in Malignant Stroke-Prone Spontaneously Hypertensive Rats.
- Short Term Hypercholesterolemia Alters NG-Nitro-L-arginine- and Indomethacin-Resistant Endothelium-Dependent Relaxation by Acetylcholine in Rabbit Renal Artery.
3
- (1S,2R)-1-Pheny1-2-[(S)-1-aminopropy1]-N,N-diethylcyclopropane-carboxamide (PPDC), a New Class of NMDA-Receptor Antagonist: Molecular Design by a Novel Conformational Restriction Strategy.
- Molecular Mechanisms for .ALPHA.2-Adrenoceptor-Mediated Regulation of Synoviocyte Populations.
- Protective Effect of Ninjin-yoei-to on Damage to Isolated Hepatocytes Following Transient Exposure to tert-Butyl Hydroperoxide.
- Vasorelaxant Effects of Pramanicin, an Anti-fungal Agent: Selective Action on Endothelial Cells.
- The Influence of Phosphodiesterase Inhibitor, Rolipram, on Hemodynamics in Lipopolysaccharide-Treated Rats.
- Role of Mast Cells in Antigen-Induced Airway Inflammation and Bronchial Hyperresponsiveness in Rats.
- State-Dependent Inhibition of L-type Ca2+ in A7r5 Cells by Cilnidipine and Its Derivatives.
- Na+/H+ Exchange Inhibitor SM-20220 Improves Endothelial Dysfunction Induced by Ischemia-Reperfusion.
- Phosphate Stimulates Differentiation and Mineralization of the Chondroprogenitor Clone ATDC5.
- TRK-820, a Selective .KAPPA.-Opioid Agonist, Produces Potent Antinociception in Cynomolgus Monkeys.
- The Properties of Carbachol-Activated Nonselective Cation Channels at the Single Channel Level in Guinea Pig Gastric Myocytes.
- Comparative Study on the Vasorelaxant Effects of Three Harmala Alkaloids In Vitro.
- Involvement of Tyrosine Hydroxylase Upregulation in Cyclosporine-Induced Hypertension.
- Blood Pressure and Heart Rate Are Increased by AF-DX 116, a Selective M2 Antagonist, in Autonomic Imbalanced and Hypotensive Rats Caused by Repeated Cold Stress.
- Presence of Aldose Reductase Inhibitors in Tea Leaves.
- Comparison of Noradrenergic and Serotonergic Antidepressants in Reducing Immobility Time in the Tail Suspension Test.
- Utilization of Telemetry System to Assess the Cardiovascular Profile of AH-1058, a New Cardioselective Ca2+ Channel Blocker,in Conscious Dogs.
- Antinociceptive Effect of Vitamin K2 (Menatetrenone) in Diabetic Mice.
4
- Molecular Pharmacology of T-type Ca2+ Channels.
- Chloride Channels and Their Functional Roles in Smooth Muscle Tone in the Vasculature.
- Role of Reduced Glutathione and Nitric Oxide in the Black Tea Extract-Mediated Protection Against Ulcerogen-Induced Changes in Motility and Gastric Emptying in Rats.
- Angiotensin-Converting Enzyme Inhibitors and AT1-Receptor Antagonist Restore Nitric Oxide Synthase (NOS) Activity and Neuronal NOS Expression in the Adrenal Glands of Spontaneously Hypertensive Rats.
- Blocking Effect of Bepridil on Na+/Ca2+ Exchange Current in Guinea Pig Cardiac Ventricular Myocytes.
- Extracellular ATP Potentiates Steroidogenic Effect of Adrenocorticotropic Hormone in Bovine Adrenocortical Fasciculata Cells.
- Imaging of Ca2+ Release by Caffeine and 9-Methyl-7-bromoeudistomin D and the Associated Activation of Large Conductance Ca2+-Dependent K+ Channels in Urinary Bladder Smooth Muscle Cells of the Guinea Pig.
- Gentamicin Decreases the Abundance of Aquaporin Water Channels in Rat Kidney.
- Inhibitory Potential of Herbal Medicines on Human Cytochrome P450-Mediated Oxidation: Properties of Umbelliferous or Citrus Crude Drugs and Their Relative Prescriptions.
- Comparison of Cedar Pollen-Induced Allergic Rhinitis in Passively and Actively Sensitized Guinea Pigs.
- Involvement of Angiotensin II in Progression of Renal Injury in Rats With Genetic Non-insulin-Dependent Diabetes Mellitus (Wistar Fatty Rats).
- Pharmacological Properties of R-755, a Novel Acyl-CoA: Cholesterol Acyltransferase Inhibitor, in Cholesterol-Fed Rats, Hamsters and Rabbits.
- Altered Susceptibility to Ischemia-Reperfusion Injury in Isolated-Perfused Hearts of Short-Term Diabetic Rats Associated With Changes in Non-enzymatic Antioxidants.
- D-Galactose-Specific Sea Urchin Lectin Sugar-Specifically Inhibited Histamine Release Induced by Datura stramonium Agglutinin: Differences Between Sugar-Specific Effects of Sea Urchin Lectin and Those of D-Galactose- or L-Fucose-Specific Plant Lectins.
- Effects of Olopatadine Hydrochloride on the Increase of Histamine and Peptide-Leukotrienes Concentrations in Nasal Lavage Fluid Following the Antigen-Antibody Reaction in Actively Sensitized Guinea Pigs.
Supplement 1
86
- Synaptic and Non-synaptic AMPA Receptors Permeable to Calcium.
- Modulation of Hippocampal Long-Term Potentiation by the Amygdala: A Synaptic Mechanism Linking Emotion and Memory.
- Electrophysiologic Effects of an Antiarrhythmic Agent, Bidisomide, on Sodium Current in Isolated Rat Ventricular Myocytes: Comparison With Mexiletine and Disopyramide.
- Mechanism of Atropine-Resistant Contraction Induced by Dai-kenchu-to in Guinea Pig Ileum.
- Do Mucosal Mast Cells Contribute to the Immediate Asthma Response?
- Modification of the Effects of Benzodiazepines on the Exploratory Behaviors of Mice on a Hole-Board by Diabetes.
- VUF-K-8788, a Periphery-Selective Histamine H1 Antagonist With Anti-pruritic Activities.
- Localization of Metallothionein (MT) and Expression of MT Isoforms Induced by Cadmium in Rat Dental Pulp.
- In Vivo Assessment of the Regulatory Mechanism of Cholinergic Neuronal Activity Associated With Motility in Dog Small Intestine.
- Comparison of the Angiotensin II Type 1-Receptor Antagonist YM358 and the Angiotensin-Converting Enzyme Inhibitor Enalapril in Rats With Cardiac Volume Overload.
- Incadronate and Etidronate Accelerate Phosphate-Primed Mineralization of MC4 Cells via ERK1/2-Cbfal Signaling Pathway in a Ras-Independent Manner: Further Involvement of Mevalonate-Pathway Blocade for Incadronate.
- Roles of Mast Cells and Histamine in Mosquito Bite-Induced Allergic Itch-Associated Responses in Mice.
- Ca2+-Images of Smooth Muscle Cells and Endothelial Cells in One Confocal Plane in Femoral Artery Segments of the Rat.
- Slowing Na+ Channel Inactivation Prolongs QT Interval and Aggravates Adrenaline-Induced Arrhythmias.
- NTE-122, an Acyl-CoA: Cholesterol Acyltransferase Inhibitor, Prevents the Progression of Atherogenesis in Cholesterol-Fed Rabbits.
- An Orally Active Chymase Inhibitor, BCEAB, Suppresses Heart Chymase Activity in the Hamster.
- Postprandial Hyperlipidemia in Zucker Diabetic Fatty fa/fa Rats, an Animal Model of Type II Diabetes, and Its Amelioration by Acyl-CoA: Cholesterol Acyltransferase Inhibition.
- Suppressive Effect of Tranilast on Interleukin-5 Prolonged Eosinophils Survival via Apoptosis.
- Method for Recording Spinal Reflexes in Mice: Effects of Thyrotropin-Releasing Hormone, DOI, Tolperisone and Baclofen on Monosynaptic Spinal Reflex Potentials.
2
- Estrogen and Cerebrovascular Physiology and Pathophysiology.
- Adrenomedullin Inhibits the Pressor Effects and Decrease in Renal Blood Flow Induced by Norepinephrine or Angiotensin II in Anesthetized Rats.
- Effect of TAK-637, a Tachykinin NK1-Receptor Antagonist, on Lower Urinary Tract Function in Cats.
- Markedly Increased Nasal Blockage by Intranasal Leukotriene D4 in an Experimental Allergic Rhinitis Model: Contribution of Dilated Mucosal Blood Vessels.
- Long Term Effects of Toki-shakuyaku-san on Brain Dopamine and Nerve Growth Factor in Olfactory-Bulb-Lesioned Mice.
- Affinity of Serotonin Receptor Antagonists and Agonists to Recombinant and Native .ALPHA.1-Adrenoceptor Subtypes.
- Involvement of Neuropeptides in the Allergic Nasal Obstruction in Guinea Pigs.
- Possible Roles of Cardiac Chymase After Myocardial Infarction in Hamster Hearts.
- Enhancement of Phenylephrine-Induced Contraction in the Isolated Rat Aorta With Endothelium by H2O-Extract From an Oriental Medicinal Plant Leonuri herba.
- Structure-Activity Relationships of Triterpenoid Derivatives Extracted From Gymnema inodorum Leaves on Glucose Absorption.
- NO-Flurbiprofen Attenuates Excitotoxin-Induced Brain Inflammation, and Releases Nitric Oxide in the Brain.
- Involvement of Nitric Oxide and Vasoactive Intestinal Peptide in the Nonadrenergic-Noncholinergic Relaxation of the Porcine Retractor Penis Muscle.
- GTP.GAMMA.S-Induced Ca2+ Activated Cl- Currents: Its Stable Induction by Gq.ALPHA. Overexpression in Xenopus Oocytes.
- Dominant Anti-vagal Effect of Pentobarbital on Cardiac Responses to Intracardiac Autonomic Nerve Stimulation in the Dog.
- Diltiazem Ameliorates Contractile Dysfunction Without Shortening of Action Potential Duration in Ischemic Heart of Anesthetized Dogs.
- Effects of Adenosine A1- and A2A-Receptor Agonists on Enhancement of Dopamine Release From the Striatum in Methamphetamine-Sensitized Rats.
- Inhibitory Effect of Olopatadine Hydrochloride on the Sneezing Response Induced by Intranasal Capsaicin Challenge in Guinea Pigs.
- Endothelium-Dependent Relaxation in Response to Low Concentrations of Bradykinin Is Enhanced by Phosphoramidon, Bosentan and BQ-123 in Bovine Coronary Arteries In Vitro.
3
- Adenosine, Oxidative Stress and Cytoprotection.
- Current Perspective. Drugs for the Treatment of Allergic Diseases.
- Effects of YM905, a Novel Muscarinic M3-Receptor Antagonist, on Experimental Models of Bowel Dysfunction In Vivo.
- Effects of Fluvastatin and Its Major Metabolites on Low-Density Lipoprotein Oxidation and Cholesterol Esterification in Macrophages.
- Effects of L-Arginine on Penicillin-Induced Epileptiform Activity in Rats.
- Mechanism of 7, 12-Dimethylbenz[a]anthracene-Induced Immunotoxicity: Role of Metabolic Activation at the Target Organ.
- Contribution of Chloride Channel Activation to the Elevated Muscular Tone of the Pulmonary Artery in Monocrotaline-Induced Pulmonary Hypertensive Rats.
- Involvement of GABAergic Systems in Manifestation of Pharmacological Activity of Desipramine.
- Hormonal Effects of Z-350, Possessing Steroid 5.ALPHA.-Reductase Inhibitory and .ALPHA.1-Adrenoceptor Antagonistic Actions, in the Rat.
- Protective Effect of Neurotropin Against Lipopolysaccharide-Induced Hypotension and Lethality Linked to Suppression of Inducible Nitric Oxide Synthase Induction.
- Nociception and Allodynia/Hyperalgesia Induced by Intrathecal Administration of Fenvalerate.
- Usefulness and Limitation of DiBAC4(3), a Voltage-Sensitive Fluorescent Dye, for the Measurement of Membrane Potentials Regulated by Recombinant Large Conductance Ca2+ -Activated K+ Channels in HEK293 Cells.
- Transient Prevention of Ethanol-Induced Gastric Lesion by Capsaicin Due to Release of Endogenous Calcitonin Gene-Related Peptide in Rats.
- Time-Dependent Apoptotic Development and Pro-apoptotic Genes. Expression in Rat Heart After Myocardial Infarction.
- Effects of HSP-117, a Novel Tachykinin NK1-Receptor Antagonist, on Cisplatin-Induced Pica as a New Evaluation of Delayed Emesis in Rats.
- Effects of .BETA.-Casomorphins on Neuronal Survival in Culture of Embryonic Chick Dorsal Root Ganglion Neurons.
- Opposite Effects of Calcium and Magnesium on the Central Blood Pressure Regulation in the Spontaneously Hypertensive Rats.
4
- Identifying Endothelium-Derived Hyperpolarizing Factor: Recent Approaches to Assay the Role of Epoxyeicosatrienoic Acids.
- Strategy for Modulation of Central Dopamine Transmission Based on the Partial Agonist Concept in Schizophrenia Therapy.
- Possible Involvement of Calcium-Calmodulin Pathways in the Positive Chronotropic Response to Angiotensin II on the Canine Cardiac Sympathetic Ganglia.
- Mechanism of a Nitric Oxide Donor NOR 1-Induced Relaxation in Longitudinal Muscle of Rat Proximal Colon.
- Changes of Tissue Factor-Dependent Coagulant Activity Mediated by Adhesion Between Polymorphonuclear Leukocytes and Endothelial Cells.
- Transactivation of Core Binding Factor .ALPHA.1 as a Basic Mechanism to Trigger Parathyroid Hormone-Induced Osteogenesis.
- Effect of 1DMe, a Neuropeptide FF Analog, on Acetylcholine Release From Myenteric Plexus of Guinea Pig Ileum.
- Involvement of .BETA.2-Adrenergic and .MU.-Opioid Receptors in Antinociception Produced by Intracerebroventricular Administration of .ALPHA.,.BETA.-Methylene-ATP.
- Excitation of Rat Striatal Large Neurons by Dopamine and/or Glutamate Released From Nerve Terminals via Presynaptic Nicotinic Receptor (.ALPHA.4.BETA.2 Type) Stimulation.
- Effects of Dehydroepiandrosterone on Oleic Acid Formation in the Liver of Rats, Mice and Guinea Pigs.
- Age-Related Decrease in Calcitonin Gene-Related Peptide mRNA in the Dorsal Root Ganglia of Spontaneously Hypertensive Rats.
- Effects of Histidine on Working Memory Deficits Induced by the 5-HT1A-Receptor Agonist 8-OH-DPAT.
1
87
- Potassium Channels of Glial Cells: Distribution and Function.
- .BETA.-Adrenoceptors: Three-Dimensional Structures and Binding Sites for Ligands.
- Gastric Acid Secretion by Central Injection of Dynorphin A-(1-17), an Endogenous Ligand of .KAPPA.-Opioid Receptor, in Urethane-Anesthetized Rats.
- In Vivo Antiarrhythmic Profile of AP-792 Assessed in Different Canine Arrhythmia Models.
- Effects of Antimuscarinic Drugs on Both Urinary Frequency and Cognitive Impairment in Conscious, Nonrestrained Rats.
- Antiischemic Properties of Fasudil in Experimental Models of Vasospastic Angina.
- The Upregulation by Peplomycin of Signal Transduction in Human Cells.
- Carboxy-PTIO Increases the Tetrahydrobiopterin Level in Mouse Brain Microvascular Endothelial Cells.
- Antioxidative Activity of Natural Isorhapontigenin.
- Effects of Phytoestrogens on Acetylcholine- and Isoprenaline-Induced Vasodilation in Rat Aorta.
- Acute Electropharmacological Effects of Intravenously Administered Amiodarone Assessed in the In Vivo Canine Model.
- Effects of Nipradilol, a Nitric Oxide-Releasing .BETA.-Adrenoceptor Blocking Agent, on Phosphoenolpyruvate Carboxykinase Gene Transcription in a Rat Hepatoma Cell Line.
- Dosing Time-Dependent Effect of Trandolapril on the Prevention of Cardiac Hypertrophy in Rats With Aortic Banding.
- Inhibition of Expression of Ornithine Decarboxylase by c-myc Antisense Oligonucleotide at the Promotion Stage of Lung Tumorigenesis in Mice.
- 2-Arachidonoylglycerol and Anandamide Oppositely Modulate Norepinephrine Release from the Rat Heart Sympathetic Nerves.
2
- Brain Drug Targeting and Gene Technologies.
- Neurobiology of the Edg2 Lysophosphatidic Acid Receptor.
- Protective Effect of FR183998, a Na+/H+ Exchange Inhibitor, Against Postischemic Injury After Normothermic and Prolonged Hypothermic Ischemia in Isolated Perfused Rat Hearts.
- Lowered Susceptibility of Muscarinic Receptor Involved in Salivary Secretion of Streptozotocin-Induced Diabetic Rats.
- Inhibition by Clonidine of the Carbachol-Induced Tension Development and Nonselective Cationic Current in Guinea Pig Ileal Myocytes.
- Role of Adenosine in Renal Protection Induced by a Brief Episode of Ischemic Preconditioning in Rats.
- Effect of .BETA.-Hydroxybutyrate, a Cerebral Function Improving Agent, on Cerebral Hypoxia, Anoxia and Ischemia in Mice and Rats.
- Efficacy of the Inflammatory Cell Infiltration Inhibitor IS-741 on Colitis Induced by Dextran Sulfate Sodium in the Rat.
- Acidosis Inhibits Gallbladder Contraction Mediated by Protein Kinase C Activation.
- Beneficial Effect of .ALPHA.-Tocopherol in Renal Ischemia-Reperfusion in Rats.
- Effects of Olopatadine Hydrochloride on the Cutaneous Vascular Hyperpermeability and the Scratching Behavior Induced by Poly-L-Arginine in Rats.
3
- Physiological and Pharmacological Role of Lysophosphatidic Acid as Modulator in Mechanotransduction.
- Hepatoprotective Drugs for the Treatment of Virus-Induced Chronic Hepatitis: From Hypercarcinogenic State to Hypocarcinogenic State.
- Adenylate Cyclase/Protein Kinase A Signaling Pathway Enhances Angiogenesis Through Induction of Vascular Endothelial Growth Factor In Vivo.
- Assessment of Affinity and Dissociation Ability of a Newly Synthesized 5-HT2 Antagonist, AT-1015: Comparison With Other 5-HT2 Antagonists.
- Deterioration of Spatial Learning Performances in Lipopolysaccharide-Treated Mice.
- Activation of a Potassium Conductance by Extracellular Alkaline pH in Oocytes of Xenopus laevis.
- Effects of Calcium Antagonists on the Nitrergic Nerve Function in Canine Corpus Cavernosum.
- A Novel Analgesic Compound OT-7100 Attenuates Nociceptive Responses in Animal Models of Inflammatory and Neuropathic Hyperalgesia: A Possible Involvement of Adenosinergic Anti-nociception.
- The Influence of the Protein Kinase A System in Differentiation of HL-60-Eo Cells to Eosinophils Induced by Histamine.
- A Comparative Study of the Fluoroquinolone Antibacterial Agents on the Action Potential Duration in Guinea Pig Ventricular Myocardia.
- Activation of Background Membrane Conductance by the Tyrosine Kinase Inhibitor Tyrphostin A23 and Its Inactive Analog Tyrphostin A1 in Guinea Pig Ventricular Myocytes.
- Ameliorative Effects of Azaindolizinone Derivative ZSET845 on Scopolamine-Induced Deficits in Passive Avoidance and Radial-Arm Maze Learning in the Rat.
4
- Dissecting Receptor-Mediated Ca2+ Influx Pathways: TRP Channels and Their Native Counterparts.
- Absence of Endothelium in Invertebrate Blood Vessels: Significance of Endothelium and Sympathetic Nerve/Medial Smooth Muscle in the Vertebrate Vascular System.
- Spinorphin, an Endogenous Inhibitor of Enkephalin-Degrading Enzymes, Potentiates Leu-Enkephalin-Induced Anti-allodynic and Antinociceptive Effects in Mice.
- Involvement of Potassium Channels in Spinal Antinociceptions Induced by Fentanyl, Clonidine and Bethanechol in Rats.
- Role of Dopaminergic System in Core Part of Nucleus Accumbens in Hyperlocomotion and Rearing Induced by MK-801 in Rats: A Behavioral and In Vivo Microdialysis Study.
- Protective Effect of Salvia miltiorrhiza on Angiotensin II-Induced Hypertrophic Responses in Neonatal Rat Cardiac Cells.
- Characteristics of Learning and Memory Impairment Induced by .DELTA.9-Tetrahydrocannabinol in Rats.
- Origin of Ca2+ for Carbachol-Induced Contraction in Longitudinal Muscle of the Proximal Colon of Rats.
- A Potential Role of Bradykinin in Angiogenesis and Growth of S-180 Mouse Tumors.
- Addition of Maitake D-fraction Reduces the Effective Dosage of Vancomycin for the Treatment of Listeria-Infected Mice.
- Effects of a .KAPPA.-Receptor Agonist U-50488 on Bulbar Respiratory Neurons and Its Antagonistic Action Against the .MU. Receptor-Induced Respiratory Depression in Decerebrate Cats.
- Protective Effects of Puerariae flos Against Ethanol-Induced Apoptosis on Human Neuroblastoma Cell Line SK-N-MC.
- NMDA Receptors in the Spinal Cord Exert Excitatory Influences on Spinal Motor Output in Rats.
1
| Copyright (c) 2006-2007 Japan Science and Technology Agency. All Rights Reserved. | |
