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Annual Report of the Pharmacopsychiatry Research Foundation
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Annual Report of the Pharmacopsychiatry Research Foundation
- Pharmacological differences in exocytosis mechanisms between dopamine, serotonin and glutamate in rat prefrontal cortex.
- Study on the involvement of binding factors with tau protein in its polymerization for the treatment of neurodegenerative dementia.
- Polymorphism analysis on the vgf gene in neuropsychiatric diseases.
- Methamphetamine-induced gene expression in the brains of developing rats and behavioral sensitization.
- Effects of Cys23Ser in 5-HT2C receptor gene on the receptor function and the association between Cys23Ser and mental disorders.
- The induction of ADRG#34 after chromic antidepressant treatment and repeated electroconvlusive treatment in rat brain.
- The investigation of the bHLH transcription factor changed by mood stabilizer.
- Candidate gene approach at the susceptible region of chromosome 21q22.3 for bipolar disorder. A novel putative Ca2+ channel protein TRPC7.
- Effects of lithium and valproate on calcium homeostasis. Relevant to the pathophysiology of bipolar disorder.
- The Longitudinal Study of Neuroendocrine and Brain Metabolic Dysfunction in Depression. DEX/CRH and [18F] FDG-PET.
- [11C](+)McN5652 binding in patients with mood disorders.
- Applicability of antipsychotic monopharmacy and dose reduction for patients with chronic schizophrenia.
- Impact of atypical antipsychotics on quality of life in patients with schizophrenia.
- Magnetic resonance spectroscopy of drug-induced extrapyramidal disorders.
- Genetic association between cytochrome P-450 2D6 polymorphism and risperidone plasma concentration.
- Effect of risperidone on methamphetamine psychosis.
- Memantine, but not bromocriptine, prevents the development of hyperthermia in an animal model of the serotonin syndrome.
- Regulation of dopamine D2 receptor-mediated endocytosis by Arc-binding protein endophilin.
- Protective Roles of Antioxidative Reagents on 6-Hydroxydopamine-Induced Apoptotic Neuronal Cell Death.
- Comprehensive database of gene expression in the animal model of acute psychotic state.
- Effects of the adenosine A1 receptor agonist N6-cyclopentyladenosine on phencyclidine-induced expression of immediate-early genes in the rat brain.
- Effect of Diazepam, Risperidon, Fluvoxzmine on phencyclidine-induced social behavior deficit in mice.
- The distribution of serotonin transpoter immunoreactivity in the hippocampal formation of schizophrenic brain.
- Mechanism of action of atypical antipsychotic drugs. A possible involvement of the interaction of glutamate and serotonergic systems in the medial prefrontal cortex.
- IS Pro15Ser Polymorphism Able to Affect the Signal Transduction of 5-HT5A Receptor?
- Are the endocannabinoids responsible for schizophrenia, especially the negative symptoms? A preclinical approach.
- Study on the molecular mechanism of D-serine metabolism and its application for the development of novel anti-schizophrenic drugs.
- The mechanism of intracytoplasmic aggregation of tau protein in neurodegenerative diseases.
- Free radical scavenging ability of laminin.
- The gene encoding a newly discovered protein, chorein, is mutated in chorea-acanthocytosis.
- Effect of methylphenidate on brain function in children with attention deficit hyperactivity disorder.
- Molecular genetics of opioid analgesia and reward.
- The exploration of genes related to depression using an animal model.
- Cyclic AMP-responsive element binding protein in the postmortem frontal cortex of depressed patients and controls.
- Association Study between a Functional Monoamine Oxidase A Gene Polymorphism and Completed Suicides.
- The impact of CYP2D*5 allele on haloperidol metabolism in a Japanese psychiatric population.
- Pharmacokinetics and pharmacogenetics of tricyclic antidepressant in advanced cancer patients.
- Anxiogenic Effect of Corticotropin-Releasing Factor 2 Receptor Antisense Oligonucleotides Infused into Rat Brain.
- Effects of corticosterone on firing activity of hippocampus CA1 pyramidal neurons.
- Failure in stress adaptation in the patients with depression. Focused on sensory gating system.
- Functional analysis of a novel clock gene Bmal2.
- Association of nuclecotide polymorphisms in human clock-relevant genes with circadin rhythm sleep disoraders.
- An immunohistochemical study on the brain mechanism of REM-sleep regulation.
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