Inhibitory Effect of a Formulation Containing 0.5% Magnolignan (5,5'-dipropyl-biphenyl-2,2'-diol) on UV-induced Skin Pigmentation
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Accession number;06A0504975
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| Title;Inhibitory Effect of a Formulation Containing 0.5% Magnolignan (5,5'-dipropyl-biphenyl-2,2'-diol) on UV-induced Skin Pigmentation |
| Author;
TAKEDA KATSUYUKI
(Univ. of Tokushima)
YOKOTA TOMOHIRO
(Kanebokeshohin)
IKEMOTO TAKESHI
(Kanebokeshohin)
KAKISHIMA HIROSHI
(Kanebokeshohin)
MATSUO TOORU
(Kanebokeshohin)
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Journal Title;Nishinihon Journal of Dermatology
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Journal Code:G0894B
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ISSN:0386-9784
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VOL.68;NO.3;PAGE.288-292(2006)
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| Figure&Table&Reference;FIG.3, TBL.4, REF.12 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;A double-blind test was performed on human subjects to determine the efficacy of formulations containing 0.5% Magnolignan (5,5'-dipropyl-biphenyl-2,2'-diol) for treatment of UV-induced pigmentation. Two adjacent test areas were selected on the inside of the upper arm of 43 subjects. A significant difference in the pigmentation score was observed after 3 weeks of application of a formulation containing 0.5% Magnolignan in comparison with a placebo. Furthermore, the improvement in .DELTA.L values were significantly different after 3 weeks compared with the placebo. No unfavorable skin reaction such as irritation, etc., was observed during the test period. In conclusion, the formulation containing 0.5% Magnolignan was found to be safe and effective for topical application in treating UV-induced pigmentation. These data indicate that Magnolignan is an effective whitening ingredient that can be used in cosmetics. (author abst.) |
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