Skill to use codeine phosphate in cancer pain patients

Accession number;06A0389877
Title;Skill to use codeine phosphate in cancer pain patients
Author;SUZUKI TAKAHIRO(Toukyourinkaibyouin)   
Journal Title;Pain Clinic
Journal Code:G0739B
ISSN:0388-4171
VOL.27;NO.;PAGE.S55-S58(2006)
Figure&Table&Reference;FIG.2, TBL.1, REF.10
Pub. Country;Japan
Language;Japanese
Abstract;Codeine phosphate belongs to the weak opioid analgesics of the WHO treatment model for cancer pain. About 35% of cancer patients can enjoy pain relief by step 2 treatment of which codeine phosphate plays a central role. The method causes less side-effects than morphine. Prescription of 80 to 120 mg of codeine phosphate is given each day at the beginning, and the amount can be increased up to 300 mg. Concomitant use of acetaminophen can enhance its analgesic effect. Codeine phosphate still can cause a variety of side-effects such as nausea, vomition, constipation, drowsiness, dry mouth, pruritus, and anuresis. Slow-release fentanyl patches can replace codeine phosphate when a large amount of codeine phosphate is necessary to contain pain.