Mexoryl XL: A new UV protective agent.

Accession number;04A0360702
Title;Mexoryl XL: A new UV protective agent.
Author;FORESTIER S(L'oreal)   ORTIZ S(Nihonrorearu Kenkaise)   JITSUKAWA SETSUKO(Nihonrorearu Kenkaise)   
Journal Title;Fragr J
Journal Code:G0987B
ISSN:0288-9803
VOL.32;NO.4;PAGE.59-64(2004)
Figure&Table&Reference;FIG.11, REF.10
Pub. Country;Japan
Language;Japanese
Abstract;Mexoryl XL (a hydroxyphenyl benzotriazole derivative) is a new UV protective agent developed by L'Oreal. The molecule is safe and stable, and absorbs UVB as well as UVA. This UV absorber exerts UV protection by converting the absorbed light energy into thermal one via its keto-enol tautomerism. Mexoryl XL increases its UV protection efficiency (PFA and SPF) when it is used with Mexoryl SX, another UV protective agent (UVA specific absorber). A photo-protective formulation with UV protective agents of different absorbance specificity (Mexoryl XL, Mexoryl SX, octocrylene and avobenzone) was found to be effective for preventing photo-induced skin problems, such as polymorphous light eruption and photosensitive lupus erythmatosus. Mexoryl XL was approved by the Ministry of Health, Labor and Walfare in December 2002 and the first product "Anthelios XL" has been launched on the Japanese market since February 2003. (author abst.)