RECONSTRUCTION OF THE MANDIBLE USING BIORESORBABLE POLY[L-LACTIDE]MESH AND AUTOGENIC PARTICULATE CANCELLOUS BONE AND MARROW AND APPLICATION OF DENTAL IMPLANT

Accession number;04A0146649
Title;RECONSTRUCTION OF THE MANDIBLE USING BIORESORBABLE POLY[L-LACTIDE]MESH AND AUTOGENIC PARTICULATE CANCELLOUS BONE AND MARROW AND APPLICATION OF DENTAL IMPLANT
Author; KINOSHITA YUKIHIKO (Kanagawa Dental Coll., JPN) YOKOYA SHIGETOSHI (Kanagawa Dental Coll., JPN) MIZUTANI NARITAKA (Kanagawa Dental Coll., JPN) AMAGASA TERUO (Tokyo Medical and Dental Univ., Faculty of Dentistry) KUDO KEIGO (Iwate Medical Univ., School of Dentistry, JPN) NAGAYAMA MASARU (Univ. of Tokushima, Sch. of Dent.) OKABE SADAO (Saitamaganse Kokugeka) TOTSUKA YASUNORI (Hokkaido Univ., Sch. of Dent.) FURUTA ISAO (Toyama Med. and Pharm. Univ.)
Journal Title;Head and Neck Cancer
Journal Code:Y0503A
ISSN:0911-4335
VOL.26;NO.3;PAGE.525-530(2000)
Figure&Table&Reference;FIG.4, TBL.2, REF.20
Pub. Country;Japan
Language;Japanese
Abstract;The purpose of this study was to clarify evaluation of reconstruction of the mandible with poly-[L-Lactide] (PLLA) mesh and transplantation of autogenic particulate cancellous bone and marrow (PCBM), and to pursue the possibility of dental implantation in the regenerated bone. We studied 41 patients (19 with malignant tumors, and 22 with benign lesions) treated at seven hospitals between 1995 and 1998, on whom mandiblectomies had been performed. Sixteen cases were treated with marginal mandiblectomy, 23 with segmental resection of the mandible, and 2 with hemi-mandiblectomy. Twenty-three cases were given simultaneous reconstruction, and the other 18 received reconstruction one year or more after the first mandiblectomy. As the results, 19 (46.3%) of the 41 cases were evaluated as excellent, 13 (31.7%) as good, and 9 (22.2%) as poor. In 6 of the cases evaluated as poor, local infections were noted, and of these, the mandibule and soft tissue were simultaneously reconstructed in 4 cases. With the only exception of these cases, the success rate for the reconstruction was 86.5 percent. In five years, the longest period of observation, no abnormalities originating in the PLLA mesh were seen. Furthermore, dental implantations were performed in the reconstructed mandible, and good osseointegration was recognized. In conclusion, it is suggested that a combination of PLLA mesh and PCBM is useful in mandibular reconstruction and dental implantation in the regenerated bone. (author abst.)