| Accession number;03A0692202 |
| Title;A New Dermatological Availability of the Flavonoid Fraction from Licorice Roots-Effect on Acne- |
| Author;KAMBARA TOSHIMITSU(Maruzenseiyaku Sokenmaruzenseiyaku Soken) ZHOU Y(Maruzenseiyaku Sokenmaruzenseiyaku Soken) KAWASHIMA YOSHIHITO(Maruzenseiyaku Sokenmaruzenseiyaku Soken) KISHIDA NAOKO(Maruzenseiyaku Sokenmaruzenseiyaku Soken) MIZUTANI KENJI(Maruzenseiyaku Sokenmaruzenseiyaku Soken) IKEDA TAKAO(Maruzenseiyaku Sokenmaruzenseiyaku Soken) KAMEYAMA KOICHIRO(Aoyamahifukakurinikku) |
Journal Title;Journal of SCCJ
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Journal Code:S0078A
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ISSN:0387-5253
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VOL.37;NO.3;PAGE.179-186(2003)
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| Figure&Table&Reference;FIG.1, TBL.7, REF.12 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;In the course of our studies on the further application of licorice as a cosmetic ingredient, we studied a new dermatological availability in the licorice extract containing licochalcone-A as a main principle, Polyol Soluble Licorice Extract P-U, prepared from the roots of Glycyrrhiza inflata Batalin. As a result, this extract showed several activities such as inhibitory actions of testosterone 5.ALPHA.-reductase, lipase and phospholipase A2, as well as androgen receptor antagonist, antimicrobial and SOD-like actions, which relate to skin care, especially the suppression of acne formation and development. On basis of this evidence, a trial of Polyol Soluble Licorice Extract P-U with acne patients was carried out and the efficacy was demonstrated clinically. (author abst.) |
