| Accession number;03A0015802 |
| Title;Treatment of Skin Defects and Skin Ulcers with bFGF Preparation. |
| Author;OGINO AKIHIRO(Tohodai I Sakurabyoin Keiseigeka) ONISHI KIYOSHI(Tohodai I Sakurabyoin Keiseigeka) YOSHIDA HIROKO(Tohodai I Sakurabyoin Keiseigeka) MARUYAMA YU(Tohodai I Keiseigeka) |
Journal Title;Japanese Pharmacology & Therapeutics
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Journal Code:Z0947A
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ISSN:0386-3603
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VOL.30;NO.11;PAGE.943-947(2002)
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| Figure&Table&Reference;FIG.9, TBL.1, REF.16 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;On 11 patients with skin defect and refractory ulcer, treatment was conducted using bFGF preparations. Good granulation, epithelialization and reduction of ulcer were observed in all patients by once-daily spraying of this product after washing the topical region. This preparation is a drug developed aiming at the basic fibroblast-proliferating factor playing an important role in the wound healing process in the body and expecting the therapeutic effects on refractory skin ulcer. Although there are some restrictions including the tropical conditions such as infection and adherence of necrosed tissues and careful administration to the patients with a past history of malignant tumor, its good therapeutic effects were expected in the patients ineffective with other drugs, and this product was evaluated to be useful from the viewpoint of QOL, such as shortening of treatment period, reduction of cost and low invasion. (author abst.) |
