| Accession number;02A0292803 |
| Title;Clinical Utility of ABCL(Agalicus Mushroom Extract) Treatment for C-Type Hepatitis. |
| Author;INUZUKA HAYATO(Choseibyoin) YOSHIDA TADAYOSHI(Gunma Univ., Sch. of Med.) |
Journal Title;Japanese Pharmacology & Therapeutics
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Journal Code:Z0947A
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ISSN:0386-3603
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VOL.30;NO.2;PAGE.103-107(2002)
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| Figure&Table&Reference;FIG.2, TBL.1, REF.9 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;The aims of present study are to investigate the clinical effects and safety evaluation on human volunteers with elevated .GAMMA.-GTP activity for Agaricus Blazei Condensed Liquid(Agaricus Mushroom Extract; ABCL). Agaricus extracts have various physiological active substances such as .BETA.-glucan protein complex, and various other polysaccharides. Specially, .BETA.-glucan activates cellular immunological system of macrophages and/or lymphocytes and stimulates secretion of various cytokines. A total of 20 patients(50% of men) with chronic C-type hepatites received the ABCL orally twice a day for 8 weeks. Clinical decreasing effect for serum .GAMMA.-GTP activity was found in 80% of the patients in both sexes. The toxicological findings and other side effects were not observed at all. From these results, it is considered that the ABCL is useful for patients with light hepatopathy such as C-type hepatitis. (author abst.) |
