| Accession number;01A1079433 |
| Title;Correlation between Blue Chromatic Macular Sensitivity and Optic Disc Change in Early Glaucoma Patients. |
| Author;YAMAZAKI YOSHIO(Nihondai I Ganka) TANAKA CHIZURU(Nihondai I Ganka) HAYAMIZU FUKUKO(Nihondai I Ganka) MIZUKI KENJI(Nihondai I Ganka) |
Journal Title;Journal of Japanese Ophthalmological Society
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Journal Code:Z0666A
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ISSN:0029-0203
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VOL.105;NO.11;PAGE.776-780(2001)
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| Figure&Table&Reference;TBL.3, REF.22 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Purpose: To investigate the relationship between morphological changes of the optic nerve head (ONH) and macular sensitivity(MS) determined with blue-on-yellow (B on Y) and white on white (W on W) perimetry in normal subjects and patients with glaucoma. Methods: One randomly chosen eye was evaluated in each of 28 normal subjects, 23 patients with ocular hypertension (OH), and 23 patients with early primary open-angle glaucoma (POAG). Mean values for MS by B on Y and W on W perimetry were obtained with the macular program using a modified Humphrey Field Analyzer(HFA). The Heidelberg Retina Tomograph (HRT) with software version 2.01 was used to evaluate the topographic parameters of temporal sector in ONH. Results: There was no significant difference in temporal topographic parameters of ONH among the three clinical groups. Mean values for MS of B on Y and W on W perimetry in early POAG were significantly lower than in normal subjects and OH. Mean values for MS of W on W perimetry showed no significant correlation with ONH parameters of the temporal sector. In early POAG, mean values for MS of B on Y perimetry significantly correlated with cup area, cup/disc area ratio, cup volume, and rim volume in the temporal sector of ONH. Conclusion: The measurement of mean MS of B on Y might be able to detect the glaucomatous optic nerve damage due to increased intraocular pressure prior to the morphological changes of ONH in early stages of glaucoma. (author abst.) |
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