Effects of Consumption of a Milk Fermented by the Probiotic Strain Bifidobacterium animalis DN-173010 on Colonic Transit Times in Healthy Humans.

Accession number;01A0811646
Title;Effects of Consumption of a Milk Fermented by the Probiotic Strain Bifidobacterium animalis DN-173010 on Colonic Transit Times in Healthy Humans.
Author;BOUVIER M(Chru-hopital Nord-13326 Marseille, Fra)   MEANCE S(Danone Vitapole, Fra)   BOULEY C(Danone Vitapole, Fra)   BERTA J-L(Danone Vitapole, Fra)   GRIMAUD J-C(Chru-hopital Nord-13326 Marseille, Fra)   
Journal Title;Biosci Microflora
Journal Code:X0537A
ISSN:1342-1441
VOL.20;NO.2;PAGE.43-48(2001)
Figure&Table&Reference;FIG.2, TBL.2, REF.30
Pub. Country;Japan
Language;English
Abstract;Objectives: The aim of our study was to ascertain whether the specific Bifidobacterium animalis DN-173010 fermented milk could modulate colonic transit time in humans. Bifidobacteria are a major component of the gut microflora and may interact with gut transit. Methods: The trial compared in a parallel double blind study in seventy two healthy volunteers the effect of a Bifidobacterium animalis fermented milk containing 2.6*108CFU/g living bifidobacteria versus heat-treated Bifidobacterium fermented milk on colonic transit times. The main marker was the total colonic transit time(CTT) measured with radio-opaque pellets. Segmental colonic transit times were also calculated. Results: A 11-day-consumption of this Bifidobacterium animalis DN-173 010 fermented milk significantly reduced the total CTT (-20.6%) comparatively to the initial CTT and to the control group where no significant change were recorded. The effect was more pronounced in women than in men. Conclusion: Our study demonstrated that the consumption of the fermented milk containing living Bifidobacterium animalis DN-173 010 was able to improve CTT in humans. (author abst.)