Five Suspected Cases of Nonautoimmune Fulminant Type 1 Diabetes Mellitus.
| Accession number;01A0530500 |
| Title;Five Suspected Cases of Nonautoimmune Fulminant Type 1 Diabetes Mellitus. |
| Author;SHIMIZU IKKI(Ehimekenchuobyoin Naika) FUJII YASUHISA(Ehimekenchuobyoin Naika) KONOUE ETSUSHI(Nisseki Matsuyamasekijujibyoin Naika) KONDO SHIORI(Nisseki Matsuyamasekijujibyoin Naika) ITANI OSAMU(Ehimedai Rinshokensaigaku(tonyobyonaika)) TAKEDA HARUYO(Ehimedai Rinshokensaigaku(tonyobyonaika)) HASEGAWA MASAAKI(Ehimedai Rinshokensaigaku(tonyobyonaika)) ONUMA HIROSHI(Ehimedai Rinshokensaigaku(tonyobyonaika)) MAKINO HIDEICHI(Ehimedai Rinshokensaigaku(tonyobyonaika)) |
Journal Title;Journal of the Japan Diabetic Society
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Journal Code:Z0279B
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ISSN:0021-437X
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VOL.44;NO.4;PAGE.315-322(2001)
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| Figure&Table&Reference;TBL.4, REF.31 |
| Pub. Country;Japan |
| Language;Japanese |
| Abstract;Imagawa et al. defined rapid-onset type 1 diabetes with pancreatic exocrine dysfunction as nonautoimmune fulminant type 1 diabetes mellitus based on clinical and histological studies. We studied 5 patients suspected of nonautoimmune fulminant type 1 diabetes mellitus. They did not have antibodies against glutamic acid decarboxylase, IA-2, thyroid, gastric wall, adrenal cortex, or pituitary. Of the 5 patients, 4 were women, in whom 3, the onset of nonautoimmune fulminant type 1 diabetes mellitus was associated with pregnancy or delivery. Three of the 5 patients had HLA DRB 1*0405, DQB 1*0401, as haplotype susceptible to type 1 diabetes in Japanese. Another patient had both susceptible and protective haplotypes, but the other had none of these. We suggest nonautoimmune fulminant type 1 diabetes mellitus may be related to pregnancy or the HLA DRB 1*0405, DQB 1*0401 haplotype. (author abst.) |
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