A Case of Lung Cancer with Myelodysplastic Syndrome.

Accession number;01A0366178
Title;A Case of Lung Cancer with Myelodysplastic Syndrome.
Author; ISHIBASHI HIRONORI (Tokyoishidai Daigakuin Shimpaikinogeka) AKAMATSU HIDEKI (Tokyoishidai Daigakuin Shimpaikinogeka) SUNAMORI MAKOTO (Tokyoishidai Daigakuin Shimpaikinogeka)
Journal Title;Lung Cancer
Journal Code:Y0006A
ISSN:0386-9628
VOL.41;NO.1;PAGE.79-82(2001)
Figure&Table&Reference;FIG.3, REF.14
Pub. Country;Japan
Language;Japanese
Abstract;Background: Myelodysplastic syndrome (MDS), defined as a preleukemic clonal abnormality of hematopoietic stem cells, is found frequently concomitant with non-hematologic malignancy. Cases of MDS developing secondary to chemotherapy for lung cancer are often reported, but lung cancer concomitant with primary MDS is rare. Case: MDS was diagnosed by bone marrow examination in a 77-year-old woman with anemia and a low white blood cell count. At the same time, chest roentgenogram showed a tumor in the right lower lobe. The tumor was diagnosed by CT-guided lung biopsy as stage IA (cT1N0M0) lung adenocarcinoma. Right lower lobectomy and mediastinal-hilar lymph node dissection were carried out without any complication. Histologic examination of surgical specimens showed metastasis of a small nodule near the tumor and mediastinal lymph nodes (pT3N2M0, stage IIIB). Adjuvant therapy was avoided because of her age and possible complications of chemotherapy. This patient is still alive one year after surgery. Conclusion: Resected lung cancer with primary MDS is extremely rare, and this case is the fifth report in the literature. (author abst.)