Susceptibility of Bordetella bronchiseptica Strains to Ofloxacin and 15 Commonly Used Antimicrobial Agents.

Accession number;01A0400200
Title;Susceptibility of Bordetella bronchiseptica Strains to Ofloxacin and 15 Commonly Used Antimicrobial Agents.
Author;HIGASHIDE YOSHIHIRO(Nippon Vet. and Anim. Sci. Univ.)   YOSHIDA TAKAHARU(Nippon Vet. and Anim. Sci. Univ.)   TAKAHASHI ISAMU(Nippon Vet. and Anim. Sci. Univ.)   SHIMIZU YUKI(Nippon Vet. and Anim. Sci. Univ.)   SAWADA TAKUO(Nippon Vet. and Anim. Sci. Univ.)   
Journal Title;Bulletin of Nippon Veterinary and Animal Science University
Journal Code:S0144B
ISSN:0373-8361
VOL.;NO.49;PAGE.22-26(2000)
Figure&Table&Reference;TBL.2, REF.15
Pub. Country;Japan
Language;Japanese
Abstract;Susceptibility of Bordetella bronchiseptica strains to ofloxacin(OFLX) and 15 commonly used antimicrobial agents was compared by median minimum inhibitory concentrations (MIC50S). As the results, these bacterial strains were highly susceptible to OFLX (1.56.MU.g/ml) similarly to doxycycline and tetracycline of commonly used antimicrobial agents. MIC50 of norfloxacin, oxolinic acid and kanamycin was 6.25.MU.g/ml, respectively and that of chloramphenicol was 12.5.MU.g/ml. On the other hand, susceptibility of the strains to the other antimicrobial agents of streptomycin, thiamphenicol, nalidixic acid and ampicillin was low with 50, 50, 50 and 100.MU.g/ml, respectively. Lowest susceptibility of the strains was shown to tylosin, spectinomycin, tiamulin and sulfadimethoxine with 200 or above 400.MU.g/ml. Although most (84.0%) of the strains were resistant to 1 to 4 of these antimicrobial agents, all of them were highly susceptible to OFLX. (author abst.)