Senile Changes in the Brain of a Masked Palm Civet, Paguma larvata.
| Accession number;01A0400197 |
| Title;Senile Changes in the Brain of a Masked Palm Civet, Paguma larvata. |
| Author;KAMIYA S(Nippon Veterinary And Animal Sci. Univ., Tokyo) HORI H(Nogeyama Zoological Gardens Of Yokohama, Yokohama, Jpn) YAMAMOTO Y(Nogeyama Zoological Gardens Of Yokohama, Yokohama, Jpn) TAKEDA H(Nogeyama Zoological Gardens Of Yokohama, Yokohama, Jpn) MIYAUCHI E(Nogeyama Zoological Gardens Of Yokohama, Yokohama, Jpn) TAKAISHI J(Nippon Veterinary And Animal Sci. Univ., Tokyo) YAMAGAMI T(Nippon Veterinary And Animal Sci. Univ., Tokyo) YAMANO S(Nippon Veterinary And Animal Sci. Univ., Tokyo) |
Journal Title;Bulletin of Nippon Veterinary and Animal Science University
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Journal Code:S0144B
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ISSN:0373-8361
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VOL.;NO.49;PAGE.1-4(2000)
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| Figure&Table&Reference;FIG.4, REF.13 |
| Pub. Country;Japan |
| Language;English |
| Abstract;The brain of a 28-year-old male masked palm civet, Paguma larvata, without neurological signs was examined by light microscopy and histochemistry. The amyloid-.BETA.-protein immunostaining revealed that many senile plaques were disseminated throughout the cerebral cortex. A large number of polyglucosan bodies(PGB) were found throughout the brain, especially in the cerebellar cortex. PGB were round, basophilic and PAS-positive structures. They were situated free in the neuropil. Civet PGB were immunoreactive for a monoclonal antibody to human polyglucosan. A list of other changes includes amyloid angiopathy, an accumulation of lipofuscin, axonal spheroids, fibrous thickening of leptomeninges, and perivascular accumulation of lipid-laden cells. However, Alzheimer's neurofibrillary tangles could not be found. (author abst.) |
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