Complete Remission of Hypereosinophilic Syndrome after Interferon-.ALPHA. Therapy. Report of a Case and Literature Review.

Accession number;00A0259764
Title;Complete Remission of Hypereosinophilic Syndrome after Interferon-.ALPHA. Therapy. Report of a Case and Literature Review.
Author;YOON T-Y(Chungbuk National Univ., Chungbuk, Kor)   AHN G-B(Chungbuk National Univ., Chungbuk, Kor)   CHANG S-H(Chungbuk National Univ., Chungbuk, Kor)   
Journal Title;J Dermatol
Journal Code:Z0757A
ISSN:0385-2407
VOL.27;NO.2;PAGE.110-115(2000)
Figure&Table&Reference;FIG.3, TBL.1, REF.34
Pub. Country;Japan
Language;English
Abstract;Hypereosinophilic syndrome (HES) is a multisystem disease with a significant mortality rate. It is characterized by peripheral blood eosinophilia and infiltration of eosinophils into many organs including skin. We describe a patient with cutaneous, pulmonary, and gastric symptoms of HES. He was first treated with systemic and topical corticosteroids, antihistamines, and photochemotherapy. Therapy was switched to interferon-.ALPHA., because we had to consider side effects of corticosteroids and no significant improvement had been achieved. During the period of usage of interferon-.ALPHA. for 50 weeks, his symptoms of HES nearly cleared. There has been no recurrence in the eight months since the discontinuation of interferon-.ALPHA. therapy. (author abst.)
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