The Use of Rectal Misoprostol as Active Pharmacological Management of the Third Stage of Labor.

Accession number;99A0894036
Title;The Use of Rectal Misoprostol as Active Pharmacological Management of the Third Stage of Labor.
Author;DIAB K M(Ain Shams Univ., Cairo, Egy)   RAMY A R(Ain Shams Univ., Cairo, Egy)   YEHIA M A(Ain Shams Univ., Cairo, Egy)   
Journal Title;J Obstet Gynaecol Res
Journal Code:Y0696A
ISSN:1341-8076
VOL.25;NO.5;PAGE.327-332(1999)
Figure&Table&Reference;TBL.4, REF.25
Pub. Country;Japan
Language;English
Abstract;Objective: To compare the effectiveness of rectal Misoprostol versus combined intramuscular oxytocin and ergometrine (O-E) in the management of the third stage of labor. Methods: Low-risk women in 3rd stage of labor were allocated to receive either rectal Misoprostol [200 ug (n = 25), 400 ug (n = 45)] or 5-units oxytocin and 0.2 mg ergometrine intramuscularly (n = 75). Clinical and hematological parameters were compared using t and chi-square tests. Results: Both groups were well matched and had similar duration of the 3rd-stage of labor. Misoprostol users had lower 3rd-stage estimated blood loss and needed less further ecbolics compared to O-E group. Postpartum Hb and Hct levels were significantly lower in O-E group than Misoprostol group. Postpartum hypertension occurred more in O-E group. Subjects in Misoprostol group had more shivering. Subjects receiving 200 ug and 400 ug Misoprostol had similar outcome variables. Conclusion: Rectal Misoprostol may be used safely in the management of the third stage of labor. (author abst.)
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