Adenocarcinoma with Signet Ring Cells of the Axilla: Two Case Reports and Review of the Literature.

Accession number;99A0539253
Title;Adenocarcinoma with Signet Ring Cells of the Axilla: Two Case Reports and Review of the Literature.
Author;KUNO Y(Nagoya City Univ. Medical School, Nagoya, Jpn)   TSUJI T(Nagoya City Univ. Medical School, Nagoya, Jpn)   YAMAMOTO K(Nagoya City Johoku Hospital, Nagoya, Jpn)   
Journal Title;J Dermatol
Journal Code:Z0757A
ISSN:0385-2407
VOL.26;NO.6;PAGE.390-395(1999)
Figure&Table&Reference;FIG.6, TBL.1, REF.16
Pub. Country;Japan
Language;English
Abstract;Adenocarcinoma with signet ring cells (ASRC) is a rare skin neoplasm whose histology shows a solid tumor intermingled with signet ring cells in variable numbers. There have been only ten reported cases. All were elderly males affected on the eyelids except for a single case in the axilla. Two new patients with ASRC of the axilla are described. In both of them, immunohistochemical studies revealed neoplastic cells that had differentiated toward apocrine glands. These are the second and third reported cases of ASRC in the axilla, one of them is the first ASRC case in a female. It seemed that the apocrine sweat gland or aberrant breast tissue in the axilla were possible origins of these tumors. (author abst.)
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